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Items: 6


Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors.

Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee HY, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ.

Sci Transl Med. 2017 Feb 8;9(376). pii: eaah5645. doi: 10.1126/scitranslmed.aah5645.


Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multicase Diamond-Blackfan anemia families.

Mirabello L, Macari ER, Jessop L, Ellis SR, Myers T, Giri N, Taylor AM, McGrath KE, Humphries JM, Ballew BJ, Yeager M, Boland JF, He J, Hicks BD, Burdett L, Alter BP, Zon L, Savage SA.

Blood. 2014 Jul 3;124(1):24-32. doi: 10.1182/blood-2013-11-540278. Epub 2014 May 14.


Simvastatin and t-butylhydroquinone suppress KLF1 and BCL11A gene expression and additively increase fetal hemoglobin in primary human erythroid cells.

Macari ER, Schaeffer EK, West RJ, Lowrey CH.

Blood. 2013 Jan 31;121(5):830-9. doi: 10.1182/blood-2012-07-443986. Epub 2012 Dec 6.


Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway.

Macari ER, Lowrey CH.

Blood. 2011 Jun 2;117(22):5987-97. doi: 10.1182/blood-2010-10-314096. Epub 2011 Apr 4.


A cell stress signaling model of fetal hemoglobin induction: what doesn't kill red blood cells may make them stronger.

Mabaera R, West RJ, Conine SJ, Macari ER, Boyd CD, Engman CA, Lowrey CH.

Exp Hematol. 2008 Sep;36(9):1057-72. doi: 10.1016/j.exphem.2008.06.014. Review.


ICP34.5-dependent and -independent activities of salubrinal in herpes simplex virus-1 infected cells.

Bryant KF, Macari ER, Malik N, Boyce M, Yuan J, Coen DM.

Virology. 2008 Sep 30;379(2):197-204. doi: 10.1016/j.virol.2008.06.028. Epub 2008 Aug 6.

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