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Mitochondrial Proteolysis and Metabolic Control.
Ahola S, Langer T, MacVicar T.
Cold Spring Harb Perspect Biol. 2019 Jul 1;11(7). pii: a033936. doi: 10.1101/cshperspect.a033936. Review.
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ROMO1 is a constituent of the human presequence translocase required for YME1L protease import.
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J Cell Biol. 2019 Feb 4;218(2):598-614. doi: 10.1083/jcb.201806093. Epub 2018 Dec 31.
Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.
Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T.
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Instant Clue: A Software Suite for Interactive Data Visualization and Analysis.
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Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation.
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Elife. 2016 Aug 6;5. pii: e16078. doi: 10.7554/eLife.16078.
OPA1 processing in cell death and disease - the long and short of it.
MacVicar T, Langer T.
J Cell Sci. 2016 Jun 15;129(12):2297-306. doi: 10.1242/jcs.159186. Epub 2016 May 17. Review.
Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells.
MacVicar TD, Mannack LV, Lees RM, Lane JD.
Int J Mol Sci. 2015 Jun 11;16(6):13356-80. doi: 10.3390/ijms160613356.
Impaired OMA1-dependent cleavage of OPA1 and reduced DRP1 fission activity combine to prevent mitophagy in cells that are dependent on oxidative phosphorylation.
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J Cell Sci. 2014 May 15;127(Pt 10):2313-25. doi: 10.1242/jcs.144337. Epub 2014 Mar 14.
Mitophagy.
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A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochondrial import and oxidative stress.
Betin VM, MacVicar TD, Parsons SF, Anstee DJ, Lane JD.
Autophagy. 2012 Apr;8(4):664-76. doi: 10.4161/auto.19227. Epub 2012 Apr 1.
SulA-induced filamentation in Salmonella enterica serovar Typhimurium: effects on SPI-1 expression and epithelial infection.
Humphrey S, Macvicar T, Stevenson A, Roberts M, Humphrey TJ, Jepson MA.
J Appl Microbiol. 2011 Jul;111(1):185-96. doi: 10.1111/j.1365-2672.2011.05022.x. Epub 2011 Apr 21.
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