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Items: 1 to 50 of 61

1.

Evaluating Augmented Depression Therapy (ADepT): study protocol for a pilot randomised controlled trial.

Dunn BD, Widnall E, Reed N, Taylor R, Owens C, Spencer A, Kraag G, Kok G, Geschwind N, Wright K, Moberly NJ, Moulds ML, MacLeod AK, Handley R, Richards D, Campbell J, Kuyken W.

Pilot Feasibility Stud. 2019 Apr 27;5:63. doi: 10.1186/s40814-019-0438-1. eCollection 2019.

2.

An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials.

Henderson CJ, Kapelyukh Y, Scheer N, Rode A, McLaren AW, MacLeod AK, Lin D, Wright J, Stanley LA, Wolf CR.

Drug Metab Dispos. 2019 Jun;47(6):601-615. doi: 10.1124/dmd.119.086397. Epub 2019 Mar 25.

3.

Working adults' well-being: An online self-help goal-based intervention.

Oliver JJ, MacLeod AK.

J Occup Organ Psychol. 2018 Sep;91(3):665-680. doi: 10.1111/joop.12212. Epub 2018 Mar 23.

4.

Metabolism of deltamethrin and cis- and trans-permethrin by human expressed cytochrome P450 and carboxylesterase enzymes.

Hedges L, Brown S, MacLeod AK, Vardy A, Doyle E, Song G, Moreau M, Yoon M, Osimitz TG, Lake BG.

Xenobiotica. 2019 May;49(5):521-527. doi: 10.1080/00498254.2018.1474283. Epub 2018 Jun 4.

PMID:
29779438
5.

Identification of Novel Pathways of Osimertinib Disposition and Potential Implications for the Outcome of Lung Cancer Therapy.

MacLeod AK, Lin, Huang JT, McLaughlin LA, Henderson CJ, Wolf CR.

Clin Cancer Res. 2018 May 1;24(9):2138-2147. doi: 10.1158/1078-0432.CCR-17-3555. Epub 2018 Feb 6.

6.

Xenobiotic CAR Activators Induce Dlk1-Dio3 Locus Noncoding RNA Expression in Mouse Liver.

Pouché L, Vitobello A, Römer M, Glogovac M, MacLeod AK, Ellinger-Ziegelbauer H, Westphal M, Dubost V, Stiehl DP, Dumotier B, Fekete A, Moulin P, Zell A, Schwarz M, Moreno R, Huang JTJ, Elcombe CR, Henderson CJ, Roland Wolf C, Moggs JG, Terranova R.

Toxicol Sci. 2017 Aug 1;158(2):367-378. doi: 10.1093/toxsci/kfx104.

PMID:
28541575
7.

Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer.

MacLeod AK, Acosta-Jimenez L, Coates PJ, McMahon M, Carey FA, Honda T, Hayes JD, Henderson CJ, Wolf CR.

Br J Cancer. 2017 Aug 22;117(5):e1. doi: 10.1038/bjc.2017.80. Epub 2017 Mar 21.

8.

Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer.

MacLeod AK, Acosta-Jimenez L, Coates PJ, McMahon M, Carey FA, Honda T, Henderson CJ, Wolf CR.

Br J Cancer. 2016 Dec 6;115(12):1530-1539. doi: 10.1038/bjc.2016.363. Epub 2016 Nov 8. Erratum in: Br J Cancer. 2017 Aug 22;117(5):e1.

9.

Application of Mice Humanized for CYP2D6 to the Study of Tamoxifen Metabolism and Drug-Drug Interaction with Antidepressants.

MacLeod AK, McLaughlin LA, Henderson CJ, Wolf CR.

Drug Metab Dispos. 2017 Jan;45(1):17-22. Epub 2016 Oct 18.

10.

Well-being in Chronic Fatigue Syndrome: Relationship to Symptoms and Psychological Distress.

Jackson H, MacLeod AK.

Clin Psychol Psychother. 2017 Jul;24(4):859-869. doi: 10.1002/cpp.2051. Epub 2016 Oct 13.

PMID:
27739228
11.

Biofouling community composition across a range of environmental conditions and geographical locations suitable for floating marine renewable energy generation.

Macleod AK, Stanley MS, Day JG, Cook EJ.

Biofouling. 2016;32(3):261-76. doi: 10.1080/08927014.2015.1136822.

PMID:
26900732
12.

Future-directed thinking in first-episode psychosis.

Goodby E, MacLeod AK.

Br J Clin Psychol. 2016 Jun;55(2):93-106. doi: 10.1111/bjc.12096. Epub 2015 Oct 29.

PMID:
26514944
13.

Activation status of the pregnane X receptor influences vemurafenib availability in humanized mouse models.

MacLeod AK, McLaughlin LA, Henderson CJ, Wolf CR.

Cancer Res. 2015 Nov 1;75(21):4573-81. doi: 10.1158/0008-5472.CAN-15-1454. Epub 2015 Sep 11.

14.

Cytokine gene polymorphisms in obstructive sleep apnoea/hypopnoea syndrome.

Bielicki P, MacLeod AK, Douglas NJ, Riha RL.

Sleep Med. 2015 Jun;16(6):792-5. doi: 10.1016/j.sleep.2015.01.006. Epub 2015 Apr 7.

PMID:
25953302
15.

An enhanced in vivo stable isotope labeling by amino acids in cell culture (SILAC) model for quantification of drug metabolism enzymes.

MacLeod AK, Fallon PG, Sharp S, Henderson CJ, Wolf CR, Huang JT.

Mol Cell Proteomics. 2015 Mar;14(3):750-60. doi: 10.1074/mcp.M114.043661. Epub 2015 Jan 5.

16.

HDAC inhibitors increase NRF2-signaling in tumour cells and blunt the efficacy of co-adminstered cytotoxic agents.

McMahon M, Campbell KH, MacLeod AK, McLaughlin LA, Henderson CJ, Wolf CR.

PLoS One. 2014 Nov 26;9(11):e114055. doi: 10.1371/journal.pone.0114055. eCollection 2014.

17.

Psychological Well-Being and Anticipated Positive Personal Events: Their Relationship to Depression.

Edmondson OJ, MacLeod AK.

Clin Psychol Psychother. 2015 Sep-Oct;22(5):418-25. doi: 10.1002/cpp.1911. Epub 2014 Jul 7.

PMID:
25044547
18.

Deletion of 30 murine cytochrome p450 genes results in viable mice with compromised drug metabolism.

Scheer N, McLaughlin LA, Rode A, Macleod AK, Henderson CJ, Wolf CR.

Drug Metab Dispos. 2014 Jun;42(6):1022-30. doi: 10.1124/dmd.114.057885. Epub 2014 Mar 26.

PMID:
24671958
19.

A brief goal-setting and planning intervention to improve well-being for people with psychiatric disorders.

Farquharson L, MacLeod AK.

Psychother Psychosom. 2014;83(2):122-4. doi: 10.1159/000356332. Epub 2014 Jan 22. No abstract available.

PMID:
24457329
20.

A targeted in vivo SILAC approach for quantification of drug metabolism enzymes: regulation by the constitutive androstane receptor.

Macleod AK, Zang T, Riches Z, Henderson CJ, Wolf CR, Huang JT.

J Proteome Res. 2014 Feb 7;13(2):866-74. doi: 10.1021/pr400897t. Epub 2013 Dec 12.

21.

Underlying motivation in the approach and avoidance goals of depressed and non-depressed individuals.

Sherratt KA, MacLeod AK.

Cogn Emot. 2013;27(8):1432-40. doi: 10.1080/02699931.2013.786680. Epub 2013 Apr 29.

PMID:
23627339
22.

Genetic copy number variation and general cognitive ability.

MacLeod AK, Davies G, Payton A, Tenesa A, Harris SE, Liewald D, Ke X, Luciano M, Lopez LM, Gow AJ, Corley J, Redmond P, McNeill G, Pickles A, Ollier W, Horan M, Starr JM, Pendleton N, Thomson PA, Porteous DJ, Deary IJ.

PLoS One. 2012;7(12):e37385. doi: 10.1371/journal.pone.0037385. Epub 2012 Dec 26.

23.

A self-help, positive goal-focused intervention to increase well-being in people with depression.

Coote HM, MacLeod AK.

Clin Psychol Psychother. 2012 Jul-Aug;19(4):305-15. doi: 10.1002/cpp.1797. Epub 2012 May 21.

PMID:
22610936
24.

Well-being, positivity and mental health: an introduction to the special issue.

MacLeod AK.

Clin Psychol Psychother. 2012 Jul-Aug;19(4):279-82. doi: 10.1002/cpp.1794. Epub 2012 May 16.

PMID:
22589138
25.

Painful engagement in deliberate self-harm: The role of conditional goal setting.

Danchin CL, MacLeod AK, Tata P.

Behav Res Ther. 2010 Sep;48(9):915-20. doi: 10.1016/j.brat.2010.05.022. Epub 2010 May 27.

PMID:
20674599
26.

Genome-wide association study identifies five loci associated with lung function.

Repapi E, Sayers I, Wain LV, Burton PR, Johnson T, Obeidat M, Zhao JH, Ramasamy A, Zhai G, Vitart V, Huffman JE, Igl W, Albrecht E, Deloukas P, Henderson J, Granell R, McArdle WL, Rudnicka AR; Wellcome Trust Case Control Consortium, Barroso I, Loos RJ, Wareham NJ, Mustelin L, Rantanen T, Surakka I, Imboden M, Wichmann HE, Grkovic I, Jankovic S, Zgaga L, Hartikainen AL, Peltonen L, Gyllensten U, Johansson A, Zaboli G, Campbell H, Wild SH, Wilson JF, Gläser S, Homuth G, Völzke H, Mangino M, Soranzo N, Spector TD, Polasek O, Rudan I, Wright AF, Heliövaara M, Ripatti S, Pouta A, Naluai AT, Olin AC, Torén K, Cooper MN, James AL, Palmer LJ, Hingorani AD, Wannamethee SG, Whincup PH, Smith GD, Ebrahim S, McKeever TM, Pavord ID, MacLeod AK, Morris AD, Porteous DJ, Cooper C, Dennison E, Shaheen S, Karrasch S, Schnabel E, Schulz H, Grallert H, Bouatia-Naji N, Delplanque J, Froguel P, Blakey JD; NSHD Respiratory Study Team, Britton JR, Morris RW, Holloway JW, Lawlor DA, Hui J, Nyberg F, Jarvelin MR, Jackson C, Kähönen M, Kaprio J, Probst-Hensch NM, Koch B, Hayward C, Evans DM, Elliott P, Strachan DP, Hall IP, Tobin MD.

Nat Genet. 2010 Jan;42(1):36-44. doi: 10.1038/ng.501. Epub 2009 Dec 13.

27.

Expression and localization of rat aldo-keto reductases and induction of the 1B13 and 1D2 isoforms by phenolic antioxidants.

MacLeod AK, Kelly VP, Higgins LG, Kelleher MO, Price SA, Bigley AL, Betton GR, Hayes JD.

Drug Metab Dispos. 2010 Feb;38(2):341-6. doi: 10.1124/dmd.109.030544. Epub 2009 Nov 17.

PMID:
19920056
28.
29.

Some principles and practices of genetic biobanking studies.

Macleod AK, Liewald DC, McGilchrist MM, Morris AD, Kerr SM, Porteous DJ.

Eur Respir J. 2009 Feb;33(2):419-25. doi: 10.1183/09031936.00043508.

30.

Runs of homozygosity in European populations.

McQuillan R, Leutenegger AL, Abdel-Rahman R, Franklin CS, Pericic M, Barac-Lauc L, Smolej-Narancic N, Janicijevic B, Polasek O, Tenesa A, Macleod AK, Farrington SM, Rudan P, Hayward C, Vitart V, Rudan I, Wild SH, Dunlop MG, Wright AF, Campbell H, Wilson JF.

Am J Hum Genet. 2008 Sep;83(3):359-72. doi: 10.1016/j.ajhg.2008.08.007. Epub 2008 Aug 28. Erratum in: Am J Hum Genet. 2008 Nov;83(5):658.

31.

Future-directed thinking and depression in relapsing-remitting multiple sclerosis.

Moore AC, MacLeod AK, Barnes D, Langdon DW.

Br J Health Psychol. 2006 Nov;11(Pt 4):663-75.

PMID:
17032490
32.
33.

Hopelessness and positive and negative future thinking in parasuicide.

MacLeod AK, Tata P, Tyrer P, Schmidt U, Davidson K, Thompson S.

Br J Clin Psychol. 2005 Nov;44(Pt 4):495-504.

PMID:
16368029
34.

Influencing prescribing through effective communication skills.

Young SF, MacLeod AK.

Am J Health Syst Pharm. 2005 Dec 1;62(23):2528-30. No abstract available.

PMID:
16303912
35.

Marker densities and the mapping of ancestral junctions.

MacLeod AK, Haley CS, Woolliams JA, Stam P.

Genet Res. 2005 Feb;85(1):69-79.

PMID:
16089037
36.
37.

Well-being and the anticipation of future positive experiences: The role of income, social networks, and planning ability.

Macleod AK, Conway C.

Cogn Emot. 2005 Mar 1;19(3):357-74. doi: 10.1080/02699930441000247.

PMID:
22686648
38.
39.

Personality disorder and future-directed thinking in parasuicide.

MacLeod AK, Tata P, Tyrer P, Schmidt U, Davidson K, Thompson S; POPMACT Group.

J Pers Disord. 2004 Oct;18(5):459-66.

PMID:
15519956
40.

Drowning your sorrows? Attitudes towards alcohol in UK Jews and Protestants: a thematic analysis.

Loewenthal KM, Lee M, MacLeod AK, Cook S, Goldblatt V.

Int J Soc Psychiatry. 2003 Sep;49(3):204-15.

PMID:
14626363
41.

The suicide beliefs of Jews and Protestants in the UK: how do they differ?

Loewenthal KM, MacLeod AK, Cook S, Lee M, Goldblatt V.

Isr J Psychiatry Relat Sci. 2003;40(3):174-81.

PMID:
14619676
42.

Beliefs about alcohol among UK Jews and Protestants: do they fit the alcohol-depression hypothesis?

Loewenthal KM, MacLeod AK, Cook S, Lee M, Goldblatt V.

Soc Psychiatry Psychiatr Epidemiol. 2003 Mar;38(3):122-7.

PMID:
12616309
43.

Tolerance for depression: are there cultural and gender differences?

Loewenthal KM, Macleod AK, Lee M, Cook S, Goldblatt V.

J Psychiatr Ment Health Nurs. 2002 Dec;9(6):681-8.

PMID:
12472821
44.

Recovery of positive future thinking within a high-risk parasuicide group: results from a pilot randomized controlled trial.

MacLeod AK, Tata P, Evans K, Tyrer P, Schmidt U, Davidson K, Thornton S, Catalan J.

Br J Clin Psychol. 1998 Nov;37(4):371-9.

PMID:
9856290
45.

Right anterior prefrontal cortex activation during semantic monitoring and working memory.

MacLeod AK, Buckner RL, Miezin FM, Petersen SE, Raichle ME.

Neuroimage. 1998 Jan;7(1):41-8.

PMID:
9500832
46.

Attributions about common bodily sensations: their associations with hypochondriasis and anxiety.

MacLeod AK, Haynes C, Sensky T.

Psychol Med. 1998 Jan;28(1):225-8.

PMID:
9483700
47.

Attributions and accessibility of explanations for future events in anxiety and depression.

Byrne A, MacLeod AK.

Br J Clin Psychol. 1997 Nov;36(4):505-20.

PMID:
9403143
48.

Parasuicide, depression and the anticipation of positive and negative future experiences.

MacLeod AK, Pankhania B, Lee M, Mitchell D.

Psychol Med. 1997 Jul;27(4):973-7.

PMID:
9234475
49.

Causal attributions about common somatic sensations among frequent general practice attenders.

Sensky T, MacLeod AK, Rigby MF.

Psychol Med. 1996 May;26(3):641-6.

PMID:
8733222
50.

Anxiety, depression, and the anticipation of future positive and negative experiences.

MacLeod AK, Byrne A.

J Abnorm Psychol. 1996 May;105(2):286-9.

PMID:
8723011

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