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Innate antimicrobial immunity in the skin: A protective barrier against bacteria, viruses, and fungi.

Coates M, Blanchard S, MacLeod AS.

PLoS Pathog. 2018 Dec 6;14(12):e1007353. doi: 10.1371/journal.ppat.1007353. eCollection 2018 Dec. No abstract available.


Technologies of Exposure: Videoconferenced Distributed Medical Education as a Sociomaterial Practice.

MacLeod A, Cameron P, Kits O, Tummons J.

Acad Med. 2018 Nov 21. doi: 10.1097/ACM.0000000000002536. [Epub ahead of print]


STAT3 antisense oligonucleotide AZD9150 in a subset of patients with heavily pretreated lymphoma: results of a phase 1b trial.

Reilley MJ, McCoon P, Cook C, Lyne P, Kurzrock R, Kim Y, Woessner R, Younes A, Nemunaitis J, Fowler N, Curran M, Liu Q, Zhou T, Schmidt J, Jo M, Lee SJ, Yamashita M, Hughes SG, Fayad L, Piha-Paul S, Nadella MVP, Xiao X, Hsu J, Revenko A, Monia BP, MacLeod AR, Hong DS.

J Immunother Cancer. 2018 Nov 16;6(1):119. doi: 10.1186/s40425-018-0436-5.


Is greenery associated with mental health among residents of aged care facilities? A systematic search and narrative review.

Carver A, Lorenzon A, Veitch J, Macleod A, Sugiyama T.

Aging Ment Health. 2018 Nov 15:1-7. doi: 10.1080/13607863.2018.1516193. [Epub ahead of print]


Perivascular dendritic cells elicit anaphylaxis by relaying allergens to mast cells via microvesicles.

Choi HW, Suwanpradid J, Kim IH, Staats HF, Haniffa M, MacLeod AS, Abraham SN.

Science. 2018 Nov 9;362(6415). pii: eaao0666. doi: 10.1126/science.aao0666.


Biased agonists of the chemokine receptor CXCR3 differentially control chemotaxis and inflammation.

Smith JS, Nicholson LT, Suwanpradid J, Glenn RA, Knape NM, Alagesan P, Gundry JN, Wehrman TS, Atwater AR, Gunn MD, MacLeod AS, Rajagopal S.

Sci Signal. 2018 Nov 6;11(555). pii: eaaq1075. doi: 10.1126/scisignal.aaq1075.


Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer's disease.

Baker SK, Chen ZL, Norris EH, Revenko AS, MacLeod AR, Strickland S.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9687-E9696. doi: 10.1073/pnas.1811172115. Epub 2018 Sep 25.


Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells.

Shastri A, Choudhary G, Teixeira M, Gordon-Mitchell S, Ramachandra N, Bernard L, Bhattacharyya S, Lopez R, Pradhan K, Giricz O, Ravipati G, Wong LF, Cole S, Bhagat TD, Feld J, Dhar Y, Bartenstein M, Thiruthuvanathan VJ, Wickrema A, Ye BH, Frank DA, Pellagatti A, Boultwood J, Zhou T, Kim Y, MacLeod AR, Epling-Burnette PK, Ye M, McCoon P, Woessner R, Steidl U, Will B, Verma A.

J Clin Invest. 2018 Dec 3;128(12):5479-5488. doi: 10.1172/JCI120156. Epub 2018 Nov 5.


Working adults' well-being: An online self-help goal-based intervention.

Oliver JJ, MacLeod AK.

J Occup Organ Psychol. 2018 Sep;91(3):665-680. doi: 10.1111/joop.12212. Epub 2018 Mar 23.


Epigenetic Reprogramming with Antisense Oligonucleotides Enhances the Effectiveness of Androgen Receptor Inhibition in Castration-Resistant Prostate Cancer.

Xiao L, Tien JC, Vo J, Tan M, Parolia A, Zhang Y, Wang L, Qiao Y, Shukla S, Wang X, Zheng H, Su F, Jing X, Luo E, Delekta A, Juckette KM, Xu A, Cao X, Alva AS, Kim Y, MacLeod AR, Chinnaiyan AM.

Cancer Res. 2018 Oct 15;78(20):5731-5740. doi: 10.1158/0008-5472.CAN-18-0941. Epub 2018 Aug 22.


Author response: Early weight loss in parkinsonism predicts poor outcomes: Evidence from an incident cohort study.

Macleod AD, Myint PK, Counsell CE.

Neurology. 2018 Aug 7;91(6):287. doi: 10.1212/WNL.0000000000005937. No abstract available.


How Well Do Measurement Scales Reflect the Actual Experience of Sexuality in Mid-Life and Beyond?

Macleod A, McCabe MP.

Sex Med Rev. 2018 Jul 26. pii: S2050-0521(18)30057-X. doi: 10.1016/j.sxmr.2018.04.004. [Epub ahead of print]


Neutrophils cause obstruction of eyelid sebaceous glands in inflammatory eye disease in mice.

Reyes NJ, Yu C, Mathew R, Kunnen CM, Kalnitsky J, Redfern RL, Leonardi A, Perez VL, MacLeod AS, Gupta PK, Saban DR.

Sci Transl Med. 2018 Jul 25;10(451). pii: eaas9164. doi: 10.1126/scitranslmed.aas9164.


Pre-operative planning for fracture fixation using locking plates: device configuration and other considerations.

MacLeod AR, Pankaj P.

Injury. 2018 Jun;49 Suppl 1:S12-S18. doi: 10.1016/S0020-1383(18)30296-1.


Age-related selection bias in Parkinson's disease research: are we recruiting the right participants?

Macleod AD, Henery R, Nwajiugo PC, Scott NW, Caslake R, Counsell CE.

Parkinsonism Relat Disord. 2018 Oct;55:128-133. doi: 10.1016/j.parkreldis.2018.05.027. Epub 2018 May 31.


Differences in pathogenicity and virulence of Trypanosoma brucei gambiense field isolates in experimentally infected Balb/C mice.

Kaboré J, Camara O, Koffi M, Sanou D, Ilboudo H, Sakandé H, Camara M, De Meeûs T, Ravel S, Belem AMG, MacLeod A, Bucheton B, Jamonneau V, Thévenon S.

Infect Genet Evol. 2018 Sep;63:269-276. doi: 10.1016/j.meegid.2018.05.018. Epub 2018 May 25.


Association of glucocerebrosidase polymorphisms and mutations with dementia in incident Parkinson's disease.

Lunde KA, Chung J, Dalen I, Pedersen KF, Linder J, Domellöf ME, Elgh E, Macleod AD, Tzoulis C, Larsen JP, Tysnes OB, Forsgren L, Counsell CE, Alves G, Maple-Grødem J.

Alzheimers Dement. 2018 Oct;14(10):1293-1301. doi: 10.1016/j.jalz.2018.04.006. Epub 2018 May 21.


Metabolism of deltamethrin and cis- and trans-permethrin by human expressed cytochrome P450 and carboxylesterase enzymes.

Hedges L, Brown S, MacLeod AK, Vardy A, Doyle E, Song G, Moreau M, Yoon M, Osimitz TG, Lake BG.

Xenobiotica. 2018 Jun 4:1-7. doi: 10.1080/00498254.2018.1474283. [Epub ahead of print]


Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei.

Steketee PC, Vincent IM, Achcar F, Giordani F, Kim DH, Creek DJ, Freund Y, Jacobs R, Rattigan K, Horn D, Field MC, MacLeod A, Barrett MP.

PLoS Negl Trop Dis. 2018 May 14;12(5):e0006450. doi: 10.1371/journal.pntd.0006450. eCollection 2018 May.


T Cells Expressing the Chemokine Receptor CXCR3 Localize to Positive Patch Test Reaction Sites.

Smith JS, Suwanpradid J, MacLeod AS, Atwater AR.

Dermatitis. 2018 Jul/Aug;29(4):228-229. doi: 10.1097/DER.0000000000000367. No abstract available.


A Jacksonian approach to BPSD.

Macleod ADS.

Int J Geriatr Psychiatry. 2018 May;33(5):797-798. doi: 10.1002/gps.4825. No abstract available.


The resilience of postglacial hunter-gatherers to abrupt climate change.

Blockley S, Candy I, Matthews I, Langdon P, Langdon C, Palmer A, Lincoln P, Abrook A, Taylor B, Conneller C, Bayliss A, MacLeod A, Deeprose L, Darvill C, Kearney R, Beavan N, Staff R, Bamforth M, Taylor M, Milner N.

Nat Ecol Evol. 2018 May;2(5):810-818. doi: 10.1038/s41559-018-0508-4. Epub 2018 Mar 26.


Trabeculectomy training in England: are we safe at training? Two year surgical outcomes.

Walkden A, Huxtable J, Senior M, Lee H, Naylor S, Turner S, Ivanova K, Koppens J, Todd B, Macleod A, Sii F, Anand N, Shah P, King A, Broadway DC, Kirwan JF, McNaught A, Bhan-Bhargava A.

Eye (Lond). 2018 Jul;32(7):1253-1258. doi: 10.1038/s41433-018-0059-6. Epub 2018 Mar 12.


Innate Antiviral Immunity in the Skin.

Handfield C, Kwock J, MacLeod AS.

Trends Immunol. 2018 Apr;39(4):328-340. doi: 10.1016/ Epub 2018 Mar 8. Review.


Erysipelothrix rhusiopathiae serotype 15 associated with recurring pig erysipelas outbreaks.

Gerber PF, MacLeod A, Opriessnig T.

Vet Rec. 2018 Jun 2;182(22):635. doi: 10.1136/vr.104421. Epub 2018 Mar 8. No abstract available.


Abrupt treatments of hysteria during World War I, 1914-18.

Macleod AS.

Hist Psychiatry. 2018 Jun;29(2):187-198. doi: 10.1177/0957154X18757338. Epub 2018 Feb 26.


No evidence for association between APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations.

Kimuda MP, Noyes H, Mulindwa J, Enyaru J, Alibu VP, Sidibe I, Mumba Ngoyi D, Hertz-Fowler C, MacLeod A, Tastan Bishop Ö, Matovu E; TrypanoGEN Research Group as members of The H3Africa Consortium.

PLoS Negl Trop Dis. 2018 Feb 22;12(2):e0006300. doi: 10.1371/journal.pntd.0006300. eCollection 2018 Feb.


Identification of Novel Pathways of Osimertinib Disposition and Potential Implications for the Outcome of Lung Cancer Therapy.

MacLeod AK, Lin, Huang JT, McLaughlin LA, Henderson CJ, Wolf CR.

Clin Cancer Res. 2018 May 1;24(9):2138-2147. doi: 10.1158/1078-0432.CCR-17-3555. Epub 2018 Feb 6.


Evaluation of SNAP cPL, Spec cPL, VetScan cPL Rapid Test, and Precision PSL Assays for the Diagnosis of Clinical Pancreatitis in Dogs.

Cridge H, MacLeod AG, Pachtinger GE, Mackin AJ, Sullivant AM, Thomason JM, Archer TM, Lunsford KV, Rosenthal K, Wills RW.

J Vet Intern Med. 2018 Mar;32(2):658-664. doi: 10.1111/jvim.15039. Epub 2018 Feb 9.


Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination?

Informal Expert Group on Gambiense HAT Reservoirs, Büscher P, Bart JM, Boelaert M, Bucheton B, Cecchi G, Chitnis N, Courtin D, Figueiredo LM, Franco JR, Grébaut P, Hasker E, Ilboudo H, Jamonneau V, Koffi M, Lejon V, MacLeod A, Masumu J, Matovu E, Mattioli R, Noyes H, Picado A, Rock KS, Rotureau B, Simo G, Thévenon S, Trindade S, Truc P, Van Reet N.

Trends Parasitol. 2018 Mar;34(3):197-207. doi: 10.1016/ Epub 2018 Jan 23. Review.


Untangling chronic pain and post-concussion symptoms: the significance of depression.

Snell DL, Martin R, Macleod AD, Surgenor LJ, Siegert RJ, Hay-Smith EJC, Melzer T, Hooper GJ, Anderson T.

Brain Inj. 2018;32(5):583-592. doi: 10.1080/02699052.2018.1432894. Epub 2018 Feb 1.


Twelve tips for medical students to establish a collaborative flashcard project.

Hart-Matyas M, Taylor A, Lee HJ, Maclean MA, Hui A, Macleod A.

Med Teach. 2018 Jan 29:1-5. doi: 10.1080/0142159X.2018.1426843. [Epub ahead of print]


Experimental and numerical investigation into the influence of loading conditions in biomechanical testing of locking plate fracture fixation devices.

MacLeod A, Simpson AHRW, Pankaj P.

Bone Joint Res. 2018 Jan;7(1):111-120. doi: 10.1302/2046-3758.71.BJR-2017-0074.R2.


Modelling vocabulary development among multilingual children prior to and following the transition to school entry.

MacLeod AAN, Castellanos-Ryan N, Parent S, Jacques S, Séguin JR.

Int J Biling Educ Biling. 2018;2017:1-20. doi: 10.1080/13670050.2016.1269718. Epub 2017 Jan 3.


Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1.

Currier RB, Cooper A, Burrell-Saward H, MacLeod A, Alsford S.

PLoS Pathog. 2018 Jan 18;14(1):e1006855. doi: 10.1371/journal.ppat.1006855. eCollection 2018 Jan.


I just can't please them all and stay sane: Adult child caregivers' experiences of family dynamics in care-giving for a parent with dementia in Australia.

Tatangelo G, McCabe M, Macleod A, Konis A.

Health Soc Care Community. 2018 May;26(3):e370-e377. doi: 10.1111/hsc.12534. Epub 2018 Jan 11.


Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells.

Lee P, Gund R, Dutta A, Pincha N, Rana I, Ghosh S, Witherden D, Kandyba E, MacLeod A, Kobielak K, Havran WL, Jamora C.

Elife. 2017 Dec 4;6. pii: e28875. doi: 10.7554/eLife.28875.


Early weight loss in parkinsonism predicts poor outcomes: Evidence from an incident cohort study.

Cumming K, Macleod AD, Myint PK, Counsell CE.

Neurology. 2017 Nov 28;89(22):2254-2261. doi: 10.1212/WNL.0000000000004691. Epub 2017 Oct 27.


A polymorphism in the haptoglobin, haptoglobin related protein locus is associated with risk of human sleeping sickness within Cameroonian populations.

Ofon E, Noyes H, Mulindwa J, Ilboudo H, Simuunza M, Ebo'o V, Njiokou F, Koffi M, Bucheton B, Fogue P, Hertz-Fowler C, MacLeod A, Simo G; TrypanoGEN Research Group, as members of The H3Africa Consortium.

PLoS Negl Trop Dis. 2017 Oct 27;11(10):e0005979. doi: 10.1371/journal.pntd.0005979. eCollection 2017 Oct.


Candidate genes-based investigation of susceptibility to Human African Trypanosomiasis in Côte d'Ivoire.

Ahouty B, Koffi M, Ilboudo H, Simo G, Matovu E, Mulindwa J, Hertz-Fowler C, Bucheton B, Sidibé I, Jamonneau V, MacLeod A, Noyes H, N'Guetta SP; TrypanoGEN Research Group as members of The H3Africa Consortium.

PLoS Negl Trop Dis. 2017 Oct 23;11(10):e0005992. doi: 10.1371/journal.pntd.0005992. eCollection 2017 Oct.


"I just don't focus on my needs." The unmet health needs of partner and offspring caregivers of people with dementia: A qualitative study.

Tatangelo G, McCabe M, Macleod A, You E.

Int J Nurs Stud. 2018 Jan;77:8-14. doi: 10.1016/j.ijnurstu.2017.09.011. Epub 2017 Sep 14.


Development and validation of prognostic survival models in newly diagnosed Parkinson's disease.

Macleod AD, Dalen I, Tysnes OB, Larsen JP, Counsell CE.

Mov Disord. 2018 Jan;33(1):108-116. doi: 10.1002/mds.27177. Epub 2017 Oct 4.


Proliferative Cartilaginous Lesions in the Calcaneal Tendons of huNOG Mice.

MacLeod AM, Treuting PM, Carlson CS.

Toxicol Pathol. 2017 Oct;45(7):952-956. doi: 10.1177/0192623317734822. Epub 2017 Oct 3.


RNA Therapeutics in Oncology: Advances, Challenges, and Future Directions.

MacLeod AR, Crooke ST.

J Clin Pharmacol. 2017 Oct;57 Suppl 10:S43-S59. doi: 10.1002/jcph.957. Review.


Candidate gene polymorphisms study between human African trypanosomiasis clinical phenotypes in Guinea.

Kaboré JW, Ilboudo H, Noyes H, Camara O, Kaboré J, Camara M, Koffi M, Lejon V, Jamonneau V, MacLeod A, Hertz-Fowler C, Belem AMG, Matovu E, Bucheton B, Sidibe I; TrypanoGEN Research Group as members of The H3Africa Consortium.

PLoS Negl Trop Dis. 2017 Aug 21;11(8):e0005833. doi: 10.1371/journal.pntd.0005833. eCollection 2017 Aug.


Was Sigmund Freud's death hastened?

Macleod ADS.

Intern Med J. 2017 Aug;47(8):966-969. doi: 10.1111/imj.13504.


Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity.

Suwanpradid J, Shih M, Pontius L, Yang B, Birukova A, Guttman-Yassky E, Corcoran DL, Que LG, Tighe RM, MacLeod AS.

J Immunol. 2017 Sep 1;199(5):1827-1834. doi: 10.4049/jimmunol.1700739. Epub 2017 Jul 26.


Diversity in fall characteristics hampers effective prevention: the precipitants, the environment, the fall and the injury.

Sanders KM, Lim K, Stuart AL, Macleod A, Scott D, Nicholson GC, Busija L.

Osteoporos Int. 2017 Oct;28(10):3005-3015. doi: 10.1007/s00198-017-4145-6. Epub 2017 Jul 19.


Case of Nigeria-Acquired Human African Trypanosomiasis in United Kingdom, 2016.

Luintel A, Lowe P, Cooper A, MacLeod A, Büscher P, Brooks T, Brown M.

Emerg Infect Dis. 2017 Jul;23(7):1225-1227. doi: 10.3201/eid2307.170695.


Targeting DMPK with Antisense Oligonucleotide Improves Muscle Strength in Myotonic Dystrophy Type 1 Mice.

Jauvin D, Chrétien J, Pandey SK, Martineau L, Revillod L, Bassez G, Lachon A, MacLeod AR, Gourdon G, Wheeler TM, Thornton CA, Bennett CF, Puymirat J.

Mol Ther Nucleic Acids. 2017 Jun 16;7:465-474. doi: 10.1016/j.omtn.2017.05.007. Epub 2017 May 17.

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