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Items: 1 to 50 of 429

1.

The applicability and utility of immunohistochemical biomarkers in bladder pathology.

Akgul M, MacLennan GT, Cheng L.

Hum Pathol. 2020 Feb 6. pii: S0046-8177(20)30017-4. doi: 10.1016/j.humpath.2020.01.004. [Epub ahead of print]

PMID:
32035992
2.

Baseline characteristics of participants in the Treatment of Advanced Glaucoma Study (TAGS): A multicentre randomised controlled trial.

King AJ, Hudson J, Fernie G, Burr J, Azuara-Blanco A, Sparrow J, Barton K, Garway-Heath DF, Kernohan A, MaClennan G; TAGS research group.

Am J Ophthalmol. 2020 Jan 29. pii: S0002-9394(20)30035-0. doi: 10.1016/j.ajo.2020.01.026. [Epub ahead of print]

PMID:
32006484
3.

Early Signs Monitoring to Prevent Relapse in Psychosis and Promote Well-Being, Engagement, and Recovery: Protocol for a Feasibility Cluster Randomized Controlled Trial Harnessing Mobile Phone Technology Blended With Peer Support.

Gumley A, Bradstreet S, Ainsworth J, Allan S, Alvarez-Jimenez M, Beattie L, Bell I, Birchwood M, Briggs A, Bucci S, Castagnini E, Clark A, Cotton SM, Engel L, French P, Lederman R, Lewis S, Machin M, MacLennan G, Matrunola C, McLeod H, McMeekin N, Mihalopoulos C, Morton E, Norrie J, Reilly F, Schwannauer M, Singh SP, Smith L, Sundram S, Thomson D, Thompson A, Whitehill H, Wilson-Kay A, Williams C, Yung A, Farhall J, Gleeson J.

JMIR Res Protoc. 2020 Jan 9;9(1):e15058. doi: 10.2196/15058.

4.

Intraductal carcinoma of the prostate is an aggressive form of invasive carcinoma and should be graded.

Samaratunga H, Delahunt B, Egevad L, Srigley JR, Billis A, Bostwick DG, Camparo P, Cheng L, Clouston D, Denham J, Furusato B, Hartmann A, Jufe L, Kench J, Kenwright DN, Kristiansen G, Leite KRM, MacLennan GT, Merrimen J, Moch H, Oxley J, Pan CC, Paner G, Ro J, Sesterhenn IAM, Shanks J, Thunders M, Tsuzuki T, Wheeler T, Yaxley JW, Varma M.

Pathology. 2020 Feb;52(2):192-196. doi: 10.1016/j.pathol.2019.11.001. Epub 2019 Dec 14. Review.

PMID:
31843189
5.

ELECtric Tibial nerve stimulation to Reduce Incontinence in Care homes: protocol for the ELECTRIC randomised trial.

Booth J, Aucott L, Cotton S, Goodman C, Hagen S, Harari D, Lawrence M, Lowndes A, Macaulay L, MacLennan G, Mason H, McClurg D, Norrie J, Norton C, O'Dolan C, Skelton DA, Surr C, Treweek S.

Trials. 2019 Dec 16;20(1):723. doi: 10.1186/s13063-019-3723-7.

6.

Photodynamic Therapy Is an Effective Adjuvant Therapy for Image-Guided Surgery in Prostate Cancer.

Wang X, Ramamurthy G, Shirke AA, Walker E, Mangadlao J, Wang Z, Wang Y, Shan L, Schluchter MD, Dong Z, Brady-Kalnay SM, Walker NK, Gargesha M, MacLennan G, Luo D, Sun R, Scott B, Roy D, Li J, Basilion JP.

Cancer Res. 2020 Jan 15;80(2):156-162. doi: 10.1158/0008-5472.CAN-19-0201. Epub 2019 Nov 12.

PMID:
31719100
7.

Practical help for specifying the target difference in sample size calculations for RCTs: the DELTA2 five-stage study, including a workshop.

Cook JA, Julious SA, Sones W, Hampson LV, Hewitt C, Berlin JA, Ashby D, Emsley R, Fergusson DA, Walters SJ, Wilson EC, MacLennan G, Stallard N, Rothwell JC, Bland M, Brown L, Ramsay CR, Cook A, Armstrong D, Altman D, Vale LD.

Health Technol Assess. 2019 Oct;23(60):1-88. doi: 10.3310/hta23600.

8.

Five decades of urologic pathology: the accelerating expansion of knowledge in renal cell neoplasia.

MacLennan GT, Cheng L.

Hum Pathol. 2020 Jan;95:24-45. doi: 10.1016/j.humpath.2019.09.009. Epub 2019 Oct 23.

PMID:
31655169
9.

Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial.

Cooper K, Breeman S, Scott NW, Scotland G, Clark J, Hawe J, Hawthorn R, Phillips K, MacLennan G, Wileman S, McCormack K, Hernández R, Norrie J, Bhattacharya S; HEALTH Study Group.

Lancet. 2019 Oct 19;394(10207):1425-1436. doi: 10.1016/S0140-6736(19)31790-8. Epub 2019 Sep 12. Erratum in: Lancet. 2019 Oct 19;394(10207):e32.

10.

Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins.

Brittenden J, Cooper D, Dimitrova M, Scotland G, Cotton SC, Elders A, MacLennan G, Ramsay CR, Norrie J, Burr JM, Campbell B, Bachoo P, Chetter I, Gough M, Earnshaw J, Lees T, Scott J, Baker SA, Tassie E, Francis J, Campbell MK.

N Engl J Med. 2019 Sep 5;381(10):912-922. doi: 10.1056/NEJMoa1805186.

PMID:
31483962
11.

Photodynamic versus white light-guided treatment of non-muscle invasive bladder cancer: a study protocol for a randomised trial of clinical and cost-effectiveness.

Tandogdu Z, Lewis R, Duncan A, Penegar S, McDonald A, Vale L, Shen J, Kelly JD, Pickard R, N Dow J, Ramsay C, Mostafid H, Mariappan P, Nabi G, Creswell J, Lazarowicz H, McGrath J, Taylor E, Clark E, Maclennan G, Norrie J, Hall E, Heer R; PHOTO Trial Management Group.

BMJ Open. 2019 Sep 3;9(9):e022268. doi: 10.1136/bmjopen-2018-022268.

12.

The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial.

Beard DJ, Davies LJ, Cook JA, MacLennan G, Price A, Kent S, Hudson J, Carr A, Leal J, Campbell H, Fitzpatrick R, Arden N, Murray D, Campbell MK; TOPKAT Study Group.

Lancet. 2019 Aug 31;394(10200):746-756. doi: 10.1016/S0140-6736(19)31281-4. Epub 2019 Jul 17.

13.

Effect of hands-on interprofessional simulation training for local emergencies in Scotland: the THISTLE stepped-wedge design randomised controlled trial.

Lenguerrand E, Winter C, Siassakos D, MacLennan G, Innes K, Lynch P, Cameron A, Crofts J, McDonald A, McCormack K, Forrest M, Norrie J, Bhattacharya S, Draycott T.

BMJ Qual Saf. 2020 Feb;29(2):122-134. doi: 10.1136/bmjqs-2018-008625. Epub 2019 Jul 13.

14.

Controversial issues in Gleason and International Society of Urological Pathology (ISUP) prostate cancer grading: proposed recommendations for international implementation.

Srigley JR, Delahunt B, Samaratunga H, Billis A, Cheng L, Clouston D, Evans A, Furusato B, Kench J, Leite K, MacLennan G, Moch H, Pan CC, Rioux-Leclercq N, Ro J, Shanks J, Shen S, Tsuzuki T, Varma M, Wheeler T, Yaxley J, Egevad L.

Pathology. 2019 Aug;51(5):463-473. doi: 10.1016/j.pathol.2019.05.001. Epub 2019 Jul 3. Review.

PMID:
31279442
15.

Study protocol for a randomised controlled trial of CBT vs antipsychotics vs both in 14-18-year-olds: Managing Adolescent first episode Psychosis: a feasibility study (MAPS).

Pyle M, Broome MR, Joyce E, MacLennan G, Norrie J, Freeman D, Fowler D, Haddad PM, Shiers D, Hollis C, Smith J, Liew A, Byrne RE, French P, Peters S, Hudson J, Davies L, Emsley R, Yung A, Birchwood M, Longden E, Morrison AP.

Trials. 2019 Jul 4;20(1):395. doi: 10.1186/s13063-019-3506-1.

16.

Surgical interventions for women with stress urinary incontinence: systematic review and network meta-analysis of randomised controlled trials.

Imamura M, Hudson J, Wallace SA, MacLennan G, Shimonovich M, Omar MI, Javanbakht M, Moloney E, Becker F, Ternent L, Montgomery I, Mackie P, Saraswat L, Monga A, Vale L, Craig D, Brazzelli M.

BMJ. 2019 Jun 5;365:l1842. doi: 10.1136/bmj.l1842.

17.

Supporting Harm Reduction through Peer Support (SHARPS): testing the feasibility and acceptability of a peer-delivered, relational intervention for people with problem substance use who are homeless, to improve health outcomes, quality of life and social functioning and reduce harms: study protocol.

Parkes T, Matheson C, Carver H, Budd J, Liddell D, Wallace J, Pauly B, Fotopoulou M, Burley A, Anderson I, MacLennan G, Foster R.

Pilot Feasibility Stud. 2019 Apr 29;5:64. doi: 10.1186/s40814-019-0447-0. eCollection 2019.

18.

Distinct mutational landscape of inverted urothelial papilloma.

Akgul M, MacLennan GT, Cheng L.

J Pathol. 2019 Sep;249(1):3-5. doi: 10.1002/path.5307. Epub 2019 Jul 2.

PMID:
31119740
19.

Is trigonitis a neglected, imprecise, misunderstood, or forgotten diagnosis?

Sadeghi Z, MacLennan G, Childs SJ, Zimmern PE.

Low Urin Tract Symptoms. 2019 Sep;11(4):182-188. doi: 10.1111/luts.12264. Epub 2019 Apr 15. Review.

PMID:
30989795
20.

Differentially Expressed Genes and Molecular Pathways in an Autochthonous Mouse Prostate Cancer Model.

Verma S, Shukla S, Pandey M, MacLennan GT, Gupta S.

Front Genet. 2019 Mar 26;10:235. doi: 10.3389/fgene.2019.00235. eCollection 2019.

21.

Surgical treatments for women with stress urinary incontinence: the ESTER systematic review and economic evaluation.

Brazzelli M, Javanbakht M, Imamura M, Hudson J, Moloney E, Becker F, Wallace S, Omar MI, Shimonovich M, MacLennan G, Ternent L, Vale L, Montgomery I, Mackie P, Saraswat L, Monga A, Craig D.

Health Technol Assess. 2019 Mar;23(14):1-306. doi: 10.3310/hta23140.

22.

Cognitive-behavioural therapy for clozapine-resistant schizophrenia: the FOCUS RCT.

Morrison AP, Pyle M, Gumley A, Schwannauer M, Turkington D, MacLennan G, Norrie J, Hudson J, Bowe S, French P, Hutton P, Byrne R, Syrett S, Dudley R, McLeod HJ, Griffiths H, Barnes TR, Davies L, Shields G, Buck D, Tully S, Kingdon D.

Health Technol Assess. 2019 Feb;23(7):1-144. doi: 10.3310/hta23070.

23.

Protocol for a multicentre randomised controlled parallel-group trial to compare the effectiveness of remotely delivered cognitive-behavioural and graded exercise interventions with usual care alone to lessen the impact of fatigue in inflammatory rheumatic diseases (LIFT).

Martin KR, Bachmair EM, Aucott L, Dures E, Emsley R, Gray SR, Hewlett S, Kumar V, Lovell K, Macfarlane GJ, MacLennan G, McNamee P, Norrie J, Paul L, Ralston S, Siebert S, Wearden A, White PD, Basu N.

BMJ Open. 2019 Jan 30;9(1):e026793. doi: 10.1136/bmjopen-2018-026793.

24.

Whole mount histopathological correlation with prostate MRI in Grade I and II prostatectomy patients.

Wang M, Janaki N, Buzzy C, Bukavina L, Mahran A, Mishra K, MacLennan G, Ponsky L.

Int Urol Nephrol. 2019 Mar;51(3):425-434. doi: 10.1007/s11255-019-02083-8. Epub 2019 Jan 22.

PMID:
30671889
25.

DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial.

Cook JA, Julious SA, Sones W, Hampson LV, Hewitt C, Berlin JA, Ashby D, Emsley R, Fergusson DA, Walters SJ, Wilson ECF, MacLennan G, Stallard N, Rothwell JC, Bland M, Brown L, Ramsay CR, Cook A, Armstrong D, Altman D, Vale LD.

BMJ. 2018 Nov 5;363:k3750. doi: 10.1136/bmj.k3750. No abstract available.

26.

Contrast-enhanced ultrasound and/or colour duplex ultrasound for surveillance after endovascular abdominal aortic aneurysm repair: a systematic review and economic evaluation.

Brazzelli M, Hernández R, Sharma P, Robertson C, Shimonovich M, MacLennan G, Fraser C, Jamieson R, Vallabhaneni SR.

Health Technol Assess. 2018 Dec;22(72):1-220. doi: 10.3310/hta22720.

27.

Open randomised trial of the (Arabin) pessary to prevent preterm birth in twin pregnancy with health economics and acceptability: STOPPIT-2-a study protocol.

Norman JE, Norrie J, Maclennan G, Cooper D, Whyte S, Cunningham Burley S, Smith JBE, Shennan A, Robson SC, Thornton S, Kilby MD, Marlow N, Stock SJ, Bennett PR, Denton J.

BMJ Open. 2018 Dec 6;8(12):e026430. doi: 10.1136/bmjopen-2018-026430.

28.

Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation.

Avenell A, Robertson C, Skea Z, Jacobsen E, Boyers D, Cooper D, Aceves-Martins M, Retat L, Fraser C, Aveyard P, Stewart F, MacLennan G, Webber L, Corbould E, Xu B, Jaccard A, Boyle B, Duncan E, Shimonovich M, Bruin M.

Health Technol Assess. 2018 Nov;22(68):1-246. doi: 10.3310/hta22680.

29.

DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial.

Cook JA, Julious SA, Sones W, Hampson LV, Hewitt C, Berlin JA, Ashby D, Emsley R, Fergusson DA, Walters SJ, Wilson ECF, Maclennan G, Stallard N, Rothwell JC, Bland M, Brown L, Ramsay CR, Cook A, Armstrong D, Altman D, Vale LD.

Trials. 2018 Nov 5;19(1):606. doi: 10.1186/s13063-018-2884-0.

30.

Diagnostic Accuracy of a Rapid Biparametric MRI Protocol for Detection of Histologically Proven Prostate Cancer.

Obmann VC, Pahwa S, Tabayayong W, Jiang Y, O'Connor G, Dastmalchian S, Lu J, Shah S, Herrmann KA, Paspulati R, MacLennan G, Ponsky L, Abouassaly R, Gulani V.

Urology. 2018 Dec;122:133-138. doi: 10.1016/j.urology.2018.08.032. Epub 2018 Sep 7.

31.

Partial factorial trials: comparing methods for statistical analysis and economic evaluation.

Dakin HA, Gray AM, MacLennan GS, Morris RW, Murray DW.

Trials. 2018 Aug 16;19(1):442. doi: 10.1186/s13063-018-2818-x.

32.

Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial.

Morrison AP, Pyle M, Gumley A, Schwannauer M, Turkington D, MacLennan G, Norrie J, Hudson J, Bowe SE, French P, Byrne R, Syrett S, Dudley R, McLeod HJ, Griffiths H, Barnes TRE, Davies L, Kingdon D; FOCUS trial group.

Lancet Psychiatry. 2018 Aug;5(8):633-643. doi: 10.1016/S2215-0366(18)30184-6. Epub 2018 Jul 11.

33.

TISU: Extracorporeal shockwave lithotripsy, as first treatment option, compared with direct progression to ureteroscopic treatment, for ureteric stones: study protocol for a randomised controlled trial.

McClinton S, Cameron S, Starr K, Thomas R, MacLennan G, McDonald A, Lam T, N'Dow J, Kilonzo M, Pickard R, Anson K, Keeley F, Burgess N, Clark CT, MacLennan S, Norrie J; TISU Study Group.

Trials. 2018 May 22;19(1):286. doi: 10.1186/s13063-018-2652-1.

34.

Evaluating the impact of the genitourinary multidisciplinary tumour board: Should every cancer patient be discussed as standard of care?

Scarberry K, Ponsky L, Cherullo E, Larchian W, Bodner D, Cooney M, Ellis R, Maclennan G, Johnson B, Tabayoyong W, Abouassaly R.

Can Urol Assoc J. 2018 May 14. doi: 10.5489/cuaj.5150. [Epub ahead of print]

35.

Cancer and vitamin D supplementation: a systematic review and meta-analysis.

Goulão B, Stewart F, Ford JA, MacLennan G, Avenell A.

Am J Clin Nutr. 2018 Apr 1;107(4):652-663. doi: 10.1093/ajcn/nqx047.

PMID:
29635490
36.

Systematic Techniques to Enhance rEtention in Randomised controlled trials: the STEER study protocol.

Gillies K, Bower P, Elliott J, MacLennan G, Newlands RSN, Ogden M, Treweek SP, Wells M, Witham MD, Young B, Francis JJ.

Trials. 2018 Mar 27;19(1):197. doi: 10.1186/s13063-018-2572-0.

37.

Ser-486/491 phosphorylation and inhibition of AMPKα activity is positively associated with Gleason score, metastasis, and castration-resistance in prostate cancer: A retrospective clinical study.

Babcook MA, Akgul M, Margevicius S, MacLennan GT, Fu P, Abouassaly R, Gupta S.

Prostate. 2018 Jul;78(10):714-723. doi: 10.1002/pros.23515. Epub 2018 Mar 26.

39.

Male synthetic sling versus artificial urinary sphincter trial for men with urodynamic stress incontinence after prostate surgery (MASTER): study protocol for a randomised controlled trial.

Constable L, Cotterill N, Cooper D, Glazener C, Drake MJ, Forrest M, Harding C, Kilonzo M, MacLennan G, McCormack K, McDonald A, Mundy A, Norrie J, Pickard R, Ramsay C, Smith R, Wileman S, Abrams P; (Chief Investigator) for the MASTER Study Group.

Trials. 2018 Feb 21;19(1):131. doi: 10.1186/s13063-018-2501-2.

40.

Chest wall toxicity after hypofractionated proton beam therapy for liver malignancies.

Yeung R, Bowen SR, Chapman TR, MacLennan GT, Apisarnthanarax S.

Pract Radiat Oncol. 2018 Jul - Aug;8(4):287-293. doi: 10.1016/j.prro.2017.12.007. Epub 2017 Dec 24.

PMID:
29452863
41.

Instrumental variable methods for a binary outcome were used to informatively address noncompliance in a randomized trial in surgery.

Cook JA, MacLennan GS, Palmer T, Lois N, Emsley R.

J Clin Epidemiol. 2018 Apr;96:126-132. doi: 10.1016/j.jclinepi.2017.11.011. Epub 2017 Nov 20.

42.

Molecular testing for BRAF mutations to inform melanoma treatment decisions: a move toward precision medicine.

Cheng L, Lopez-Beltran A, Massari F, MacLennan GT, Montironi R.

Mod Pathol. 2018 Jan;31(1):24-38. doi: 10.1038/modpathol.2017.104. Epub 2017 Nov 17. Review.

43.

Effects of weight loss interventions for adults who are obese on mortality, cardiovascular disease, and cancer: systematic review and meta-analysis.

Ma C, Avenell A, Bolland M, Hudson J, Stewart F, Robertson C, Sharma P, Fraser C, MacLennan G.

BMJ. 2017 Nov 14;359:j4849. doi: 10.1136/bmj.j4849. Review.

44.

The split-plot design was useful for evaluating complex, multilevel interventions, but there is need for improvement in its design and report.

Goulão B, MacLennan G, Ramsay C.

J Clin Epidemiol. 2018 Apr;96:120-125. doi: 10.1016/j.jclinepi.2017.10.019. Epub 2017 Nov 4. Review.

PMID:
29113938
45.

Treatment of Advanced Glaucoma Study: a multicentre randomised controlled trial comparing primary medical treatment with primary trabeculectomy for people with newly diagnosed advanced glaucoma-study protocol.

King AJ, Fernie G, Azuara-Blanco A, Burr JM, Garway-Heath T, Sparrow JM, Vale L, Hudson J, MacLennan G, McDonald A, Barton K, Norrie J.

Br J Ophthalmol. 2018 Jul;102(7):922-928. doi: 10.1136/bjophthalmol-2017-310902. Epub 2017 Oct 26.

46.

Influence of chronic inflammation on Bcl-2 and PCNA expression in prostate needle biopsy specimens.

Glover M, Soni S, Ren Q, Maclennan GT, Fu P, Gupta S.

Oncol Lett. 2017 Oct;14(4):3927-3934. doi: 10.3892/ol.2017.6668. Epub 2017 Jul 26.

47.

Bayesian clinical trial designs: Another option for trauma trials?

Jansen JO, Pallmann P, MacLennan G, Campbell MK; UK-REBOA Trial Investigators.

J Trauma Acute Care Surg. 2017 Oct;83(4):736-741. doi: 10.1097/TA.0000000000001638. Erratum in: J Trauma Acute Care Surg. 2019 Apr;86(4):760.

PMID:
28930965
48.

Distinct clinicopathological features in metanephric adenoma harboring BRAF mutation.

Caliò A, Eble JN, Hes O, Martignoni G, Harari SE, Williamson SR, Brunelli M, Osunkoya AO, Wang L, Comperat E, Lopez-Beltran A, Wang M, Zhang S, Curless KL, Post KM, Chang HY, Luchini C, Baldrige LA, MacLennan GT, Montironi R, Grignon DJ, Cheng L.

Oncotarget. 2016 Aug 8;8(33):54096-54105. doi: 10.18632/oncotarget.11117. eCollection 2017 Aug 15.

49.

THISTLE: trial of hands-on Interprofessional simulation training for local emergencies: a research protocol for a stepped-wedge clustered randomised controlled trial.

Lenguerrand E, Winter C, Innes K, MacLennan G, Siassakos D, Lynch P, Cameron A, Crofts J, McDonald A, McCormack K, Forrest M, Norrie J, Bhattacharya S, Draycott T; Thistle group.

BMC Pregnancy Childbirth. 2017 Sep 7;17(1):294. doi: 10.1186/s12884-017-1455-9.

50.

The SIMS trial: adjustable anchored single-incision mini-slings versus standard tension-free midurethral slings in the surgical management of female stress urinary incontinence. A study protocol for a pragmatic, multicentre, non-inferiority randomised controlled trial.

Abdel-Fattah M, MacLennan G, Kilonzo M, Assassa RP, McCormick K, Davidson T, McDonald A, N'Dow J, Wardle J, Norrie J.

BMJ Open. 2017 Aug 11;7(8):e015111. doi: 10.1136/bmjopen-2016-015111.

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