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Mesophilic microorganisms build terrestrial mats analogous to Precambrian microbial jungles.

Finke N, Simister RL, O'Neil AH, Nomosatryo S, Henny C, MacLean LC, Canfield DE, Konhauser K, Lalonde SV, Fowle DA, Crowe SA.

Nat Commun. 2019 Sep 20;10(1):4323. doi: 10.1038/s41467-019-11541-x.


The Shillam-Clipper Leadership Minimum Demographic Data Set: A Tool for Advancing Healthcare Research.

Shillam CR, Clipper B, MacLean L.

J Nurs Adm. 2019 Oct;49(10):496-502. doi: 10.1097/NNA.0000000000000793.


In vivo detection of cerebral tau pathology in long-term survivors of traumatic brain injury.

Gorgoraptis N, Li LM, Whittington A, Zimmerman KA, Maclean LM, McLeod C, Ross E, Heslegrave A, Zetterberg H, Passchier J, Matthews PM, Gunn RN, McMillan TM, Sharp DJ.

Sci Transl Med. 2019 Sep 4;11(508). pii: eaaw1993. doi: 10.1126/scitranslmed.aaw1993.


Evaluation of a 3D-printed total knee arthroplasty using radiostereometric analysis: assessment of highly porous biological fixation of the tibial baseplate and metal-backed patellar component.

Sporer S, MacLean L, Burger A, Moric M.

Bone Joint J. 2019 Jul;101-B(7_Supple_C):40-47. doi: 10.1302/0301-620X.101B7.BJJ-2018-1466.R1.


Copper(II) complexes of coumarin-derived Schiff base ligands: Pro- or antioxidant activity in MCF-7 cells?

MacLean L, Karcz D, Jenkins H, McClean S, Devereux M, Howe O, Pereira MD, May NV, Enyedy ÉA, Creaven BS.

J Inorg Biochem. 2019 Aug;197:110702. doi: 10.1016/j.jinorgbio.2019.110702. Epub 2019 May 5.


Recovery facilities in a tertiary level hospital in Lusaka, Zambia.

Anis R, Maclean L, Kimena L, Crichton L.

Br J Nurs. 2019 May 9;28(9):571-573. doi: 10.12968/bjon.2019.28.9.571. No abstract available.


Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.

Wyllie S, Brand S, Thomas M, De Rycker M, Chung CW, Pena I, Bingham RP, Bueren-Calabuig JA, Cantizani J, Cebrian D, Craggs PD, Ferguson L, Goswami P, Hobrath J, Howe J, Jeacock L, Ko EJ, Korczynska J, MacLean L, Manthri S, Martinez MS, Mata-Cantero L, Moniz S, Nühs A, Osuna-Cabello M, Pinto E, Riley J, Robinson S, Rowland P, Simeons FRC, Shishikura Y, Spinks D, Stojanovski L, Thomas J, Thompson S, Viayna Gaza E, Wall RJ, Zuccotto F, Horn D, Ferguson MAJ, Fairlamb AH, Fiandor JM, Martin J, Gray DW, Miles TJ, Gilbert IH, Read KD, Marco M, Wyatt PG.

Proc Natl Acad Sci U S A. 2019 May 7;116(19):9318-9323. doi: 10.1073/pnas.1820175116. Epub 2019 Apr 8.


Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis.

Thomas MG, De Rycker M, Ajakane M, Albrecht S, Álvarez-Pedraglio AI, Boesche M, Brand S, Campbell L, Cantizani-Perez J, Cleghorn LAT, Copley RCB, Crouch SD, Daugan A, Drewes G, Ferrer S, Ghidelli-Disse S, Gonzalez S, Gresham SL, Hill AP, Hindley SJ, Lowe RM, MacKenzie CJ, MacLean L, Manthri S, Martin F, Miguel-Siles J, Nguyen VL, Norval S, Osuna-Cabello M, Woodland A, Patterson S, Pena I, Quesada-Campos MT, Reid IH, Revill C, Riley J, Ruiz-Gomez JR, Shishikura Y, Simeons FRC, Smith A, Smith VC, Spinks D, Stojanovski L, Thomas J, Thompson S, Underwood T, Gray DW, Fiandor JM, Gilbert IH, Wyatt PG, Read KD, Miles TJ.

J Med Chem. 2019 Feb 14;62(3):1180-1202. doi: 10.1021/acs.jmedchem.8b01218. Epub 2018 Dec 20.


Grit: A predictor of medical student performance.

Miller-Matero LR, Martinez S, MacLean L, Yaremchuk K, Ko AB.

Educ Health (Abingdon). 2018 May-Aug;31(2):109-113. doi: 10.4103/efh.EfH_152_16.


Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis.

Wyllie S, Thomas M, Patterson S, Crouch S, De Rycker M, Lowe R, Gresham S, Urbaniak MD, Otto TD, Stojanovski L, Simeons FRC, Manthri S, MacLean LM, Zuccotto F, Homeyer N, Pflaumer H, Boesche M, Sastry L, Connolly P, Albrecht S, Berriman M, Drewes G, Gray DW, Ghidelli-Disse S, Dixon S, Fiandor JM, Wyatt PG, Ferguson MAJ, Fairlamb AH, Miles TJ, Read KD, Gilbert IH.

Nature. 2018 Aug;560(7717):192-197. doi: 10.1038/s41586-018-0356-z. Epub 2018 Jul 25.


Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas' disease drug discovery.

MacLean LM, Thomas J, Lewis MD, Cotillo I, Gray DW, De Rycker M.

PLoS Negl Trop Dis. 2018 Jul 12;12(7):e0006612. doi: 10.1371/journal.pntd.0006612. eCollection 2018 Jul.


Routine Use of Radiostereometric Analysis in Elective Hip and Knee Arthroplasty Patients: Surgical Impact, Safety, and Bead Stability.

Shah RP, MacLean L, Paprosky WG, Sporer S.

J Am Acad Orthop Surg. 2018 Apr 15;26(8):e173-e180. doi: 10.5435/JAAOS-D-17-00071.


Leadership Influence: A Core Foundation for Advocacy.

Shillam CR, MacLean L.

Nurs Adm Q. 2018 Apr/Jun;42(2):150-153. doi: 10.1097/NAQ.0000000000000276.


Training pharmacy technicians to administer immunizations.

McKeirnan KC, Frazier KR, Nguyen M, MacLean LG.

J Am Pharm Assoc (2003). 2018 Mar - Apr;58(2):174-178.e1. doi: 10.1016/j.japh.2018.01.003. Epub 2018 Feb 16.


The Design of a Pulse Oximeter to MIDI Output Conversion Unit - a Technical Report.

MacLean LJ, Saab R, Gordon A, Matava CT.

J Med Syst. 2018 Jan 20;42(3):41. doi: 10.1007/s10916-018-0897-6. No abstract available.


Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani.

Torrie LS, Brand S, Robinson DA, Ko EJ, Stojanovski L, Simeons FRC, Wyllie S, Thomas J, Ellis L, Osuna-Cabello M, Epemolu O, Nühs A, Riley J, MacLean L, Manthri S, Read KD, Gilbert IH, Fairlamb AH, De Rycker M.

ACS Infect Dis. 2017 Oct 13;3(10):718-727. doi: 10.1021/acsinfecdis.7b00047. Epub 2017 Oct 2.


Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi.

Brand S, Ko EJ, Viayna E, Thompson S, Spinks D, Thomas M, Sandberg L, Francisco AF, Jayawardhana S, Smith VC, Jansen C, De Rycker M, Thomas J, MacLean L, Osuna-Cabello M, Riley J, Scullion P, Stojanovski L, Simeons FRC, Epemolu O, Shishikura Y, Crouch SD, Bakshi TS, Nixon CJ, Reid IH, Hill AP, Underwood TZ, Hindley SJ, Robinson SA, Kelly JM, Fiandor JM, Wyatt PG, Marco M, Miles TJ, Read KD, Gilbert IH.

J Med Chem. 2017 Sep 14;60(17):7284-7299. doi: 10.1021/acs.jmedchem.7b00463. Epub 2017 Aug 27.


Periodic health examinations and missed opportunities among patients likely needing mental health care.

Tai-Seale M, Hatfield LA, Wilson CJ, Stults CD, McGuire TG, Diamond LC, Frankel RM, MacLean L, Stone A, Elston Lafata J.

Am J Manag Care. 2016 Oct 1;22(10):e350-e357.


Measurement of shank angle during stance using laser range finders.

Amiri P, MacLean LJ, Kearney RE.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:3374-3377. doi: 10.1109/EMBC.2016.7591451.


Using the NANA toolkit at home to predict older adults' future depression.

Andrews JA, Harrison RF, Brown LJE, MacLean LM, Hwang F, Smith T, Williams EA, Timon C, Adlam T, Khadra H, Astell AJ.

J Affect Disord. 2017 Apr 15;213:187-190. doi: 10.1016/j.jad.2017.02.019. Epub 2017 Feb 14.


Observing prioritization effects on cognition and gait: The effect of increased cognitive load on cognitively healthy older adults' dual-task performance.

Maclean LM, Brown LJE, Khadra H, Astell AJ.

Gait Posture. 2017 Mar;53:139-144. doi: 10.1016/j.gaitpost.2017.01.018. Epub 2017 Jan 24.


Long-term health outcomes after exposure to repeated concussion in elite level: rugby union players.

McMillan TM, McSkimming P, Wainman-Lefley J, Maclean LM, Hay J, McConnachie A, Stewart W.

J Neurol Neurosurg Psychiatry. 2017 Jun;88(6):505-511. doi: 10.1136/jnnp-2016-314279. Epub 2016 Oct 7.


The relationship of endotoxaemia to peripheral and central nervous system inflammatory responses in Human African Trypanosomiasis.

Maclean L, Aboubaker EA, Kennedy PG, Sternberg JM.

Parasitology. 2017 Apr;144(4):557-562. doi: 10.1017/S0031182016002158. Epub 2016 Nov 29.


Exploring the Leishmania Hydrophilic Acylated Surface Protein B (HASPB) Export Pathway by Live Cell Imaging Methods.

MacLean L, Price H, O'Toole P.

Methods Mol Biol. 2016;1459:191-203. doi: 10.1007/978-1-4939-3804-9_13.


Unprofessional workplace conduct...defining and defusing it.

MacLean L, Coombs C, Breda K.

Nurs Manage. 2016 Sep;47(9):30-4. doi: 10.1097/ No abstract available.


Computer-based tools for assessing micro-longitudinal patterns of cognitive function in older adults.

Brown LJE, Adlam T, Hwang F, Khadra H, Maclean LM, Rudd B, Smith T, Timon C, Williams EA, Astell AJ.

Age (Dordr). 2016 Aug;38(4):335-350. doi: 10.1007/s11357-016-9934-x. Epub 2016 Jul 29.


Computerized Self-Administered Measures of Mood and Appetite for Older Adults: The Novel Assessment of Nutrition and Ageing Toolkit.

Brown LJE, Adlam T, Hwang F, Khadra H, Maclean LM, Rudd B, Smith T, Timon C, Williams EA, Astell AJ.

J Appl Gerontol. 2018 Feb;37(2):157-176. doi: 10.1177/0733464816630636. Epub 2016 Feb 10.


The Impact of Medical School on Student Mental Health.

MacLean L, Booza J, Balon R.

Acad Psychiatry. 2016 Feb;40(1):89-91. doi: 10.1007/s40596-015-0301-5. Epub 2015 Mar 7. No abstract available.


Report of the 2013-2014 Professional Affairs Standing Committee: advancing the pharmacy profession together through pharmacy technician and pharmacy education partnerships.

Mobley Smith MA, Boyle CJ, Keresztes JM, Liles J, MacLean LG, McAllister EB, Silvester J, Williams NT, Bradley-Baker LR.

Am J Pharm Educ. 2014 Dec 15;78(10):S22. doi: 10.5688/ajpe7810S22. No abstract available.


The validation of a computer-based food record for older adults: the Novel Assessment of Nutrition and Ageing (NANA) method.

Timon CM, Astell AJ, Hwang F, Adlam TD, Smith T, Maclean L, Spurr D, Forster SE, Williams EA.

Br J Nutr. 2015 Feb 28;113(4):654-64. doi: 10.1017/S0007114514003808. Epub 2015 Jan 29.


Validation of the NANA (Novel Assessment of Nutrition and Ageing) touch screen system for use at home by older adults.

Astell AJ, Hwang F, Brown LJ, Timon C, Maclean LM, Smith T, Adlam T, Khadra H, Williams EA.

Exp Gerontol. 2014 Dec;60:100-7. doi: 10.1016/j.exger.2014.10.008. Epub 2014 Oct 16.


Cytomegalovirus pouchitis in a patient with Crohn's disease.

Mabvuure NT, Maclean L, Oien K, Gaya D.

BMJ Case Rep. 2014 Jul 17;2014. pii: bcr2014205374. doi: 10.1136/bcr-2014-205374.


Faculty development program models to advance teaching and learning within health science programs.

Lancaster JW, Stein SM, MacLean LG, Van Amburgh J, Persky AM.

Am J Pharm Educ. 2014 Jun 17;78(5):99. doi: 10.5688/ajpe78599.


The structure of the polysaccharide isolated from Acinetobacter baumannii strain LAC-4.

Vinogradov E, Maclean L, Xu HH, Chen W.

Carbohydr Res. 2014 May 22;390:42-5. doi: 10.1016/j.carres.2014.03.001. Epub 2014 Mar 13.


Scale, causes, and implications of the primary care nursing shortage.

MacLean L, Hassmiller S, Shaffer F, Rohrbaugh K, Collier T, Fairman J.

Annu Rev Public Health. 2014;35:443-57. doi: 10.1146/annurev-publhealth-032013-182508. Epub 2014 Jan 9. Review.


Report of the 2012-2013 professional affairs committee: tables of influence-is pharmacy hungry enough?

Maclean LG, Brazeau GA, Chesnut RJ, Erstad BL, Gant KO, Pitman EP, Johnson JK, Musselman T, Bradley-Baker LR.

Am J Pharm Educ. 2013 Dec 16;77(10):S21. doi: 10.5688/ajpe7710S21. No abstract available.


Population genetics of Trypanosoma brucei rhodesiense: clonality and diversity within and between foci.

Duffy CW, MacLean L, Sweeney L, Cooper A, Turner CM, Tait A, Sternberg J, Morrison LJ, MacLeod A.

PLoS Negl Trop Dis. 2013 Nov 14;7(11):e2526. doi: 10.1371/journal.pntd.0002526. eCollection 2013 Nov.


Imaging African trypanosomes.

MacLean L, Myburgh E, Rodgers J, Price HP.

Parasite Immunol. 2013 Sep-Oct;35(9-10):283-94. doi: 10.1111/pim.12046. Review.


Psychiatrists' experiences of being stalked: a qualitative analysis.

Maclean L, Reiss D, Whyte S, Christopherson S, Petch E, Penny C.

J Am Acad Psychiatry Law. 2013;41(2):193-9.


The effect of rhythmic musical training on healthy older adults' gait and cognitive function.

Maclean LM, Brown LJ, Astell AJ.

Gerontologist. 2014 Aug;54(4):624-33. doi: 10.1093/geront/gnt050. Epub 2013 May 30.


Structure of the capsular polysaccharides and lipopolysaccharides from Haemophilus parasuis strains ER-6P (serovar 15) and Nagasaki (serovar 5).

Perry MB, MacLean LL, Gottschalk M, Aragon V, Vinogradov E.

Carbohydr Res. 2013 Aug 30;378:91-7. doi: 10.1016/j.carres.2013.04.023. Epub 2013 Apr 27.


Study of the population pharmacokinetic characteristics of once-daily trospium chloride 60 mg extended-release capsules in patients with overactive bladder and in healthy subjects.

Harnett MD, Shipley J, MacLean L, Schwiderski U, Sandage BW Jr.

Clin Drug Investig. 2013 Feb;33(2):133-41. doi: 10.1007/s40261-012-0039-8.


Stage progression and neurological symptoms in Trypanosoma brucei rhodesiense sleeping sickness: role of the CNS inflammatory response.

MacLean L, Reiber H, Kennedy PG, Sternberg JM.

PLoS Negl Trop Dis. 2012;6(10):e1857. doi: 10.1371/journal.pntd.0001857. Epub 2012 Oct 25.


Characterization of mercury binding onto a novel brominated biomass ash sorbent by X-ray absorption spectroscopy.

Bisson TM, MacLean LC, Hu Y, Xu Z.

Environ Sci Technol. 2012 Nov 6;46(21):12186-93. doi: 10.1021/es300991u. Epub 2012 Oct 26.


Teaching medication adherence in US colleges and schools of pharmacy.

Rickles NM, MacLean LG, Hess K, Farmer KC, Yurkon AM, Ha CC, Schwartzman E, Law AV, Milani PA, Trotta K, Labella SR, Designor RJ.

Am J Pharm Educ. 2012 Jun 18;76(5):79. doi: 10.5688/ajpe76579.


Chemical transformations of lead compounds under humid conditions: implications for bioaccessibility.

Maclean LC, Beauchemin S, Rasmussen PE.

Environ Geochem Health. 2013 Feb;35(1):153-9. doi: 10.1007/s10653-012-9467-x. Epub 2012 Jun 28.


Structure of the O-antigen polysaccharide present in the lipopolysaccharide of Cronobacter dublinensis (subspecies lactaridi or lausannensis) HPB 3169.

MacLean LL, Vinogradov E, Pagotto F, Perry MB.

Can J Microbiol. 2012 Apr;58(4):540-6. doi: 10.1139/w2012-022. Epub 2012 Apr 2.


A 1-day course to improve the teaching effectiveness of health professions faculty members.

Stein SM, Fujisaki BS, Davis SE, Maclean LG.

Am J Pharm Educ. 2012 Feb 10;76(1):15. doi: 10.5688/ajpe76115.


The orthologue of Sjögren's syndrome nuclear autoantigen 1 (SSNA1) in Trypanosoma brucei is an immunogenic self-assembling molecule.

Price HP, Hodgkinson MR, Curwen RS, MacLean LM, Brannigan JA, Carrington M, Smith BA, Ashford DA, Stark M, Smith DF.

PLoS One. 2012;7(2):e31842. doi: 10.1371/journal.pone.0031842. Epub 2012 Feb 20.

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