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Predicting renal disease progression in a large contemporary cohort with type 1 diabetes mellitus.

Colombo M, McGurnaghan SJ, Bell S, MacKenzie F, Patrick AW, Petrie JR, McKnight JA, MacRury S, Traynor J, Metcalfe W, McKeigue PM, Colhoun HM; Scottish Diabetes Research Network (SDRN) Type 1 Bioresource Investigators and the Scottish Renal Registry.

Diabetologia. 2019 Dec 5. doi: 10.1007/s00125-019-05052-z. [Epub ahead of print]


Point-of-care testing by healthcare workers for detection of meticillin-resistant Staphylococcus aureus, Clostridioides difficile, and norovirus.

Dewar S, Vass D, MacKenzie FM, Parcell BJ.

J Hosp Infect. 2019 Dec;103(4):447-453. doi: 10.1016/j.jhin.2019.08.002. Epub 2019 Aug 9.


"A Lot of People Are Struggling Privately. They Don't Know Where to Go or They're Not Sure of What to Do": Frontline Service Provider Perspectives of the Nature of Household Food Insecurity in Scotland.

Douglas F, MacKenzie F, Ejebu OZ, Whybrow S, Garcia AL, McKenzie L, Ludbrook A, Dowler E.

Int J Environ Res Public Health. 2018 Dec 4;15(12). pii: E2738. doi: 10.3390/ijerph15122738.


The impact and effect of emotional resilience on performance: an overview for surgeons and other healthcare professionals.

Murden F, Bailey D, Mackenzie F, Oeppen RS, Brennan PA.

Br J Oral Maxillofac Surg. 2018 Nov;56(9):786-790. doi: 10.1016/j.bjoms.2018.08.012. Epub 2018 Sep 13. Review.


Genetic variation affecting DNA methylation and the human imprinting disorder, Beckwith-Wiedemann syndrome.

Dagar V, Hutchison W, Muscat A, Krishnan A, Hoke D, Buckle A, Siswara P, Amor DJ, Mann J, Pinner J, Colley A, Wilson M, Sachdev R, McGillivray G, Edwards M, Kirk E, Collins F, Jones K, Taylor J, Hayes I, Thompson E, Barnett C, Haan E, Freckmann ML, Turner A, White S, Kamien B, Ma A, Mackenzie F, Baynam G, Kiraly-Borri C, Field M, Dudding-Byth T, Algar EM.

Clin Epigenetics. 2018 Aug 30;10(1):114. doi: 10.1186/s13148-018-0546-4.


Letter in response to: John W Honour. Standardization of steroid tests and implications for the endocrine community. Annals of Clinical Biochemistry, Vol. 54(6) 618-630.

MacKenzie F.

Ann Clin Biochem. 2018 May;55(3):409. doi: 10.1177/0004563218762564. Epub 2018 Mar 1. No abstract available.


Continental shelves as a variable but increasing global sink for atmospheric carbon dioxide.

Laruelle GG, Cai WJ, Hu X, Gruber N, Mackenzie FT, Regnier P.

Nat Commun. 2018 Jan 31;9(1):454. doi: 10.1038/s41467-017-02738-z.


IFCC Working Group Recommendations for Assessing Commutability Part 2: Using the Difference in Bias between a Reference Material and Clinical Samples.

Nilsson G, Budd JR, Greenberg N, Delatour V, Rej R, Panteghini M, Ceriotti F, Schimmel H, Weykamp C, Keller T, Camara JE, Burns C, Vesper HW, MacKenzie F, Miller WG; IFCC Working Group on Commutability.

Clin Chem. 2018 Mar;64(3):455-464. doi: 10.1373/clinchem.2017.277541. Epub 2018 Jan 18.


IFCC Working Group Recommendations for Assessing Commutability Part 3: Using the Calibration Effectiveness of a Reference Material.

Budd JR, Weykamp C, Rej R, MacKenzie F, Ceriotti F, Greenberg N, Camara JE, Schimmel H, Vesper HW, Keller T, Delatour V, Panteghini M, Burns C, Miller WG; IFCC Working Group on Commutability.

Clin Chem. 2018 Mar;64(3):465-474. doi: 10.1373/clinchem.2017.277558. Epub 2018 Jan 18.


IFCC Working Group Recommendations for Assessing Commutability Part 1: General Experimental Design.

Miller WG, Schimmel H, Rej R, Greenberg N, Ceriotti F, Burns C, Budd JR, Weykamp C, Delatour V, Nilsson G, MacKenzie F, Panteghini M, Keller T, Camara JE, Zegers I, Vesper HW; IFCC Working Group on Commutability.

Clin Chem. 2018 Mar;64(3):447-454. doi: 10.1373/clinchem.2017.277525. Epub 2018 Jan 18.


Glibenclamide and metfoRmin versus stAndard care in gEstational diabeteS (GRACES): a feasibility open label randomised trial.

Reynolds RM, Denison FC, Juszczak E, Bell JL, Penneycard J, Strachan MWJ, Lindsay RS, Alexander CI, Love CDB, Whyte S, Mackenzie F, Stenson B, Norman JE.

BMC Pregnancy Childbirth. 2017 Sep 22;17(1):316. doi: 10.1186/s12884-017-1505-3.


The use of error and uncertainty methods in the medical laboratory.

Oosterhuis WP, Bayat H, Armbruster D, Coskun A, Freeman KP, Kallner A, Koch D, Mackenzie F, Migliarino G, Orth M, Sandberg S, Sylte MS, Westgard S, Theodorsson E.

Clin Chem Lab Med. 2018 Jan 26;56(2):209-219. doi: 10.1515/cclm-2017-0341.


Standardization of Free Thyroxine Measurements Allows the Adoption of a More Uniform Reference Interval.

De Grande LAC, Van Uytfanghe K, Reynders D, Das B, Faix JD, MacKenzie F, Decallonne B, Hishinuma A, Lapauw B, Taelman P, Van Crombrugge P, Van den Bruel A, Velkeniers B, Williams P, Thienpont LM; IFCC Committee for Standardization of Thyroid Function Tests (C-STFT).

Clin Chem. 2017 Oct;63(10):1642-1652. doi: 10.1373/clinchem.2017.274407. Epub 2017 Jul 18.


Analytical performance specifications for external quality assessment - definitions and descriptions.

Jones GRD, Albarede S, Kesseler D, MacKenzie F, Mammen J, Pedersen M, Stavelin A, Thelen M, Thomas A, Twomey PJ, Ventura E, Panteghini M; EFLM Task Finish Group – Analytical Performance Specifications for EQAS (TFG-APSEQA).

Clin Chem Lab Med. 2017 Jun 27;55(7):949-955. doi: 10.1515/cclm-2017-0151.


Harmonization of Serum Thyroid-Stimulating Hormone Measurements Paves the Way for the Adoption of a More Uniform Reference Interval.

Thienpont LM, Van Uytfanghe K, De Grande LAC, Reynders D, Das B, Faix JD, MacKenzie F, Decallonne B, Hishinuma A, Lapauw B, Taelman P, Van Crombrugge P, Van den Bruel A, Velkeniers B, Williams P; IFCC Committee for Standardization of Thyroid Function Tests (C-STFT).

Clin Chem. 2017 Jul;63(7):1248-1260. doi: 10.1373/clinchem.2016.269456. Epub 2017 May 18.


An overview of the European Organization for External Quality Assurance Providers in Laboratory Medicine (EQALM).

Stavelin A, Albe X, Meijer P, Sarkany E, MacKenzie F.

Biochem Med (Zagreb). 2017 Feb 15;27(1):30-36. doi: 10.11613/BM.2017.005. Review.


Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration.

Athanasiou D, Aguila M, Opefi CA, South K, Bellingham J, Bevilacqua D, Munro PM, Kanuga N, Mackenzie FE, Dubis AM, Georgiadis A, Graca AB, Pearson RA, Ali RR, Sakami S, Palczewski K, Sherman MY, Reeves PJ, Cheetham ME.

Hum Mol Genet. 2017 Jan 15;26(2):305-319. doi: 10.1093/hmg/ddw387.


Monitoring the stability of the standardization status of FT4 and TSH assays by use of daily outpatient medians and flagging frequencies.

De Grande LAC, Goossens K, Van Uytfanghe K, Das B, MacKenzie F, Patru MM, Thienpont LM; IFCC Committee for Standardization of Thyroid Function Tests (C-STFT).

Clin Chim Acta. 2017 Apr;467:8-14. doi: 10.1016/j.cca.2016.04.032. Epub 2016 Apr 27.


Candidate Reference Measurement Procedure for the Quantification of Total Serum Cortisol with LC-MS/MS.

Hawley JM, Owen LJ, MacKenzie F, Mussell C, Cowen S, Keevil BG.

Clin Chem. 2016 Jan;62(1):262-9. doi: 10.1373/clinchem.2015.243576. Epub 2015 Nov 3.


Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves.

Cattin AL, Burden JJ, Van Emmenis L, Mackenzie FE, Hoving JJ, Garcia Calavia N, Guo Y, McLaughlin M, Rosenberg LH, Quereda V, Jamecna D, Napoli I, Parrinello S, Enver T, Ruhrberg C, Lloyd AC.

Cell. 2015 Aug 27;162(5):1127-39. doi: 10.1016/j.cell.2015.07.021. Epub 2015 Aug 13.


Neural crest cell-derived VEGF promotes embryonic jaw extension.

Wiszniak S, Mackenzie FE, Anderson P, Kabbara S, Ruhrberg C, Schwarz Q.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):6086-91. doi: 10.1073/pnas.1419368112. Epub 2015 Apr 28.


Development and early application of the Scottish Community Nursing Workload Measurement Tool.

Grafen M, Mackenzie FC.

Br J Community Nurs. 2015 Feb;20(2):89-92. doi: 10.12968/bjcn.2015.20.2.89.


A Progress Report of the IFCC Committee for Standardization of Thyroid Function Tests.

Thienpont LM, Van Uytfanghe K, Van Houcke S, Das B, Faix JD, MacKenzie F, Quinn FA, Rottmann M, Van den Bruel A; IFCC Committee for Standardization of Thyroid Function Tests (C-STFT).

Eur Thyroid J. 2014 Jun;3(2):109-16. doi: 10.1159/000358270. Epub 2014 May 7.


Structural characterization of human cholesterol 7α-hydroxylase.

Tempel W, Grabovec I, MacKenzie F, Dichenko YV, Usanov SA, Gilep AA, Park HW, Strushkevich N.

J Lipid Res. 2014 Sep;55(9):1925-32. doi: 10.1194/jlr.M050765. Epub 2014 Jun 13.


Human steroid and oxysterol 7α-hydroxylase CYP7B1: substrate specificity, azole binding and misfolding of clinically relevant mutants.

Yantsevich AV, Dichenko YV, Mackenzie F, Mukha DV, Baranovsky AV, Gilep AA, Usanov SA, Strushkevich NV.

FEBS J. 2014 Mar;281(6):1700-13. doi: 10.1111/febs.12733. Epub 2014 Feb 20.


Biobanking trends, challenges, and opportunities.

Mackenzie F.

Pathobiology. 2014;81(5-6):245-51. doi: 10.1159/000369825. Epub 2015 Mar 16. Review.


Norethisterone interference in testosterone assays.

Jeffery J, MacKenzie F, Beckett G, Perry L, Ayling R.

Ann Clin Biochem. 2014 Mar;51(Pt 2):284-8. doi: 10.1177/0004563213512800. Epub 2013 Nov 21.


Development of a rapid assay for the analysis of serum cortisol and its implementation into a routine service laboratory.

Owen LJ, Adaway JE, Davies S, Neale S, El-Farhan N, Ducroq D, Evans C, Rees DA, MacKenzie F, Keevil BG.

Ann Clin Biochem. 2013 Jul;50(Pt 4):345-52. doi: 10.1177/0004563212473448. Epub 2013 Jun 12.


The importance of commutability of reference materials used as calibrators: the example of ceruloplasmin.

Zegers I, Beetham R, Keller T, Sheldon J, Bullock D, MacKenzie F, Trapmann S, Emons H, Schimmel H.

Clin Chem. 2013 Sep;59(9):1322-9. doi: 10.1373/clinchem.2012.201954. Epub 2013 May 6.


Crystal structure of the human SUV39H1 chromodomain and its recognition of histone H3K9me2/3.

Wang T, Xu C, Liu Y, Fan K, Li Z, Sun X, Ouyang H, Zhang X, Zhang J, Li Y, Mackenzie F, Min J, Tu X.

PLoS One. 2012;7(12):e52977. doi: 10.1371/journal.pone.0052977. Epub 2012 Dec 28.


Emerging roles for semaphorins and VEGFs in synaptogenesis and synaptic plasticity.

Tillo M, Ruhrberg C, Mackenzie F.

Cell Adh Migr. 2012 Nov-Dec;6(6):541-6. doi: 10.4161/cam.22408. Epub 2012 Oct 17. Review.


Crystal structures of the tetratricopeptide repeat domains of kinesin light chains: insight into cargo recognition mechanisms.

Zhu H, Lee HY, Tong Y, Hong BS, Kim KP, Shen Y, Lim KJ, Mackenzie F, Tempel W, Park HW.

PLoS One. 2012;7(3):e33943. doi: 10.1371/journal.pone.0033943. Epub 2012 Mar 28.


Diverse roles for VEGF-A in the nervous system.

Mackenzie F, Ruhrberg C.

Development. 2012 Apr;139(8):1371-80. doi: 10.1242/dev.072348. Review.


Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30.

Liu K, Guo Y, Liu H, Bian C, Lam R, Liu Y, Mackenzie F, Rojas LA, Reinberg D, Bedford MT, Xu RM, Min J.

PLoS One. 2012;7(2):e30375. doi: 10.1371/journal.pone.0030375. Epub 2012 Feb 17.


Meticillin-resistant Staphylococcus aureus (MRSA): global epidemiology and harmonisation of typing methods.

Stefani S, Chung DR, Lindsay JA, Friedrich AW, Kearns AM, Westh H, Mackenzie FM.

Int J Antimicrob Agents. 2012 Apr;39(4):273-82. doi: 10.1016/j.ijantimicag.2011.09.030. Epub 2012 Jan 9. Review.


Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini.

Ouyang H, Ali YO, Ravichandran M, Dong A, Qiu W, MacKenzie F, Dhe-Paganon S, Arrowsmith CH, Zhai RG.

J Biol Chem. 2012 Jan 20;287(4):2317-27. doi: 10.1074/jbc.M111.273730. Epub 2011 Nov 8.


The Cryptosporidium parvum kinome.

Artz JD, Wernimont AK, Allali-Hassani A, Zhao Y, Amani M, Lin YH, Senisterra G, Wasney GA, Fedorov O, King O, Roos A, Lunin VV, Qiu W, Finerty P Jr, Hutchinson A, Chau I, von Delft F, MacKenzie F, Lew J, Kozieradzki I, Vedadi M, Schapira M, Zhang C, Shokat K, Heightman T, Hui R.

BMC Genomics. 2011 Sep 30;12:478. doi: 10.1186/1471-2164-12-478.


Crystal structure of the Cys2His2-type zinc finger domain of human DPF2.

Zhang W, Xu C, Bian C, Tempel W, Crombet L, MacKenzie F, Min J, Liu Z, Qi C.

Biochem Biophys Res Commun. 2011 Sep 16;413(1):58-61. doi: 10.1016/j.bbrc.2011.08.043. Epub 2011 Aug 24.


A retrospective cohort study into acquisition of MRSA and associated risk factors after implementation of universal screening in Scottish hospitals.

van Velzen EV, Reilly JS, Kavanagh K, Leanord A, Edwards GF, Girvan EK, Gould IM, Mackenzie FM, Masterton R.

Infect Control Hosp Epidemiol. 2011 Sep;32(9):889-96. doi: 10.1086/661280. Erratum in: Infect Control Hosp Epidemiol. 2011 Nov;32(11):1147.


Technical comment on Kroeker et al. (2010) Meta-analysis reveals negative yet variable effects of ocean acidification on marine organisms. Ecology Letters, 13, 1419-1434.

Andersson AJ, Mackenzie FT.

Ecol Lett. 2011 Aug;14(8):E1-2. doi: 10.1111/j.1461-0248.2011.01646.x. Epub 2011 Jun 13.


Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system.

Strushkevich N, MacKenzie F, Cherkesova T, Grabovec I, Usanov S, Park HW.

Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10139-43. doi: 10.1073/pnas.1019441108. Epub 2011 Jun 2. Erratum in: Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15535.


Meticillin-resistant Staphylococcus aureus (MRSA): screening and decolonisation.

Cookson B, Bonten MJ, Mackenzie FM, Skov RL, Verbrugh HA, Tacconelli E; European Society of Clinical Microbiology and Infectious Diseases (ESCMID); International Society of Chemotherapy (ISC).

Int J Antimicrob Agents. 2011 Mar;37(3):195-201. doi: 10.1016/j.ijantimicag.2010.10.023. Epub 2010 Dec 15.


Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1.

Tong Y, Tempel W, Wang H, Yamada K, Shen L, Senisterra GA, MacKenzie F, Chishti AH, Park HW.

Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20346-51. doi: 10.1073/pnas.1009008107. Epub 2010 Nov 5.


Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).

Xu C, Bian C, Yang W, Galka M, Ouyang H, Chen C, Qiu W, Liu H, Jones AE, MacKenzie F, Pan P, Li SS, Wang H, Min J.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19266-71. doi: 10.1073/pnas.1008937107. Epub 2010 Oct 25.


Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain.

Liu K, Chen C, Guo Y, Lam R, Bian C, Xu C, Zhao DY, Jin J, MacKenzie F, Pawson T, Min J.

Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18398-403. doi: 10.1073/pnas.1013106107. Epub 2010 Oct 11.


The effectiveness of drug round tabards in reducing incidence of medication errors.

Scott J, Williams D, Ingram J, Mackenzie F.

Nurs Times. 2010 Aug 31-Sep 6;106(34):13-5.


Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.

Davis TL, Walker JR, Campagna-Slater V, Finerty PJ, Paramanathan R, Bernstein G, MacKenzie F, Tempel W, Ouyang H, Lee WH, Eisenmesser EZ, Dhe-Paganon S.

PLoS Biol. 2010 Jul 27;8(7):e1000439. doi: 10.1371/journal.pbio.1000439.


Oral and oropharyngeal cancer in the West of Scotland-long-term outcome data of a prospective audit 1999-2001.

McMahon JD, Robertson GA, Liew C, McManners J, Mackenzie FR, Hislop WS, Morley SE, Devine J, Carton AT, Harvey S, Hunter K, Robertson AG.

Br J Oral Maxillofac Surg. 2011 Mar;49(2):92-8. doi: 10.1016/j.bjoms.2009.12.013. Epub 2010 Jun 19.


Antimicrobial resistance profiles of Campylobacter from humans, retail chicken meat, and cattle feces.

Gormley FJ, Strachan NJ, Reay K, MacKenzie FM, Ogden ID, Dallas JF, Forbes KJ.

Foodborne Pathog Dis. 2010 Sep;7(9):1129-31. doi: 10.1089/fpd.2009.0532.


Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium.

Wernimont AK, Artz JD, Finerty P Jr, Lin YH, Amani M, Allali-Hassani A, Senisterra G, Vedadi M, Tempel W, Mackenzie F, Chau I, Lourido S, Sibley LD, Hui R.

Nat Struct Mol Biol. 2010 May;17(5):596-601. doi: 10.1038/nsmb.1795. Epub 2010 May 2.

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