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Items: 31

1.

Obliquity-paced climate change recorded in Antarctic debris-covered glaciers.

Mackay SL, Marchant DR.

Nat Commun. 2017 Feb 10;8:14194. doi: 10.1038/ncomms14194.

2.

Enhanced sensitivity to chemotherapy in esophageal cancer through inhibition of NF-kappaB.

Li J, Minnich DJ, Camp ER, Brank A, Mackay SL, Hochwald SN.

J Surg Res. 2006 May;132(1):112-20. Epub 2005 Dec 9.

PMID:
16337965
3.

Inducible nuclear factor-kappaB activation contributes to chemotherapy resistance in gastric cancer.

Camp ER, Li J, Minnich DJ, Brank A, Moldawer LL, MacKay SL, Hochwald SN.

J Am Coll Surg. 2004 Aug;199(2):249-58.

PMID:
15275881
4.

Inhibition of NF-kappa B augments sensitivity to 5-fluorouracil/folinic acid in colon cancer.

Voboril R, Hochwald SN, Li J, Brank A, Weberova J, Wessels F, Moldawer LL, Camp ER, MacKay SL.

J Surg Res. 2004 Aug;120(2):178-88.

PMID:
15234211
5.

Antineoplastic therapy in colorectal cancer through proteasome inhibition.

Hochwald SN, Lind DS, Malaty J, Copeland EM 3rd, Moldawer LL, MacKay SL.

Am Surg. 2003 Jan;69(1):15-23.

PMID:
12575774
6.

Liposome-mediated, nonviral gene transfer induces a systemic inflammatory response which can exacerbate pre-existing inflammation.

Norman J, Denham W, Denham D, Yang J, Carter G, Abouhamze A, Tannahill CL, MacKay SL, Moldawer LL.

Gene Ther. 2000 Aug;7(16):1425-30.

7.

LPS-induced liver injury in D-galactosamine-sensitized mice requires secreted TNF-alpha and the TNF-p55 receptor.

Nowak M, Gaines GC, Rosenberg J, Minter R, Bahjat FR, Rectenwald J, MacKay SL, Edwards CK 3rd, Moldawer LL.

Am J Physiol Regul Integr Comp Physiol. 2000 May;278(5):R1202-9.

8.

Lipopolysaccharide and D-galactosamine-induced hepatic injury is mediated by TNF-alpha and not by Fas ligand.

Josephs MD, Bahjat FR, Fukuzuka K, Ksontini R, Solorzano CC, Edwards CK 3rd, Tannahill CL, MacKay SL, Copeland EM 3rd, Moldawer LL.

Am J Physiol Regul Integr Comp Physiol. 2000 May;278(5):R1196-201.

9.

Modulation of the acute phase response by altered expression of the IL-1 type 1 receptor or IL-1ra.

Josephs MD, Solorzano CC, Taylor M, Rosenberg JJ, Topping D, Abouhamze A, Mackay SL, Hirsch E, Hirsh D, Labow M, Moldawer LL.

Am J Physiol Regul Integr Comp Physiol. 2000 Apr;278(4):R824-30.

10.

Discordant tumor necrosis factor-alpha superfamily gene expression in bacterial peritonitis and endotoxemic shock.

Tannahill CL, Fukuzuka K, Marum T, Abouhamze Z, MacKay SL, Copeland EM 3rd, Moldawer LL.

Surgery. 1999 Aug;126(2):349-57.

PMID:
10455905
11.

Application of gene therapy to acute inflammatory diseases.

Moldawer LL, Edwards PD, Josephs M, Minter RM, Copeland EM 3rd, MacKay SL.

Shock. 1999 Aug;12(2):83-101. Review.

PMID:
10446888
12.

Characterization in vitro and in vivo of hammerhead ribozymes directed against murine tumor necrosis factoralpha.

MacKay SL, Tannahill CL, Auffenberg T, Ksontini R, Copeland EM 3rd, Moldawer LL.

Biochem Biophys Res Commun. 1999 Jul 5;260(2):390-7.

PMID:
10403780
13.

Caspase-3-dependent organ apoptosis early after burn injury.

Fukuzuka K, Rosenberg JJ, Gaines GC, Edwards CK 3rd, Clare-Salzler M, MacKay SL, Moldawer LL, Copeland EM 3rd, Mozingo DW.

Ann Surg. 1999 Jun;229(6):851-8; discussion 858-9.

14.

Human interleukin 10 suppresses production of inflammatory mediators by LPS-stimulated equine peritoneal macrophages.

Hawkins DL, MacKay RJ, MacKay SL, Moldawer LL.

Vet Immunol Immunopathol. 1998 Nov 6;66(1):1-10.

PMID:
9847016
15.

Transfection of the type II TGF-beta receptor into colon cancer cells increases receptor expression, inhibits cell growth, and reduces the malignant phenotype.

MacKay SL, Auffenberg T, Tannahill CL, Ksontini R, Josephs MD, Nowak M, Moldawer LL, Copeland EM 3rd.

Ann Surg. 1998 Jun;227(6):781-9.

16.

Enhanced collagen accumulation following direct transfection of the inducible nitric oxide synthase gene in cutaneous wounds.

Thornton FJ, Schäffer MR, Witte MB, Moldawer LL, MacKay SL, Abouhamze A, Tannahill CL, Barbul A.

Biochem Biophys Res Commun. 1998 May 29;246(3):654-9.

PMID:
9618268
17.

Revisiting the role of tumor necrosis factor alpha and the response to surgical injury and inflammation.

Ksontini R, MacKay SL, Moldawer LL.

Arch Surg. 1998 May;133(5):558-67. Review.

PMID:
9605921
18.

Pharmacokinetics, immunogenicity, and efficacy of dimeric TNFR binding proteins in healthy and bacteremic baboon.

Solorzano CC, Kaibara A, Hess PJ, Edwards PD, Ksontini R, Abouhamze A, McDaniel S, Frazier J, Trujillo D, Kieft G, Seely J, Kohno T, Cosenza ME, Clare-Salzler M, MacKay SL, Martin SW, Moldawer LL, Edwards CK 3rd.

J Appl Physiol (1985). 1998 Apr;84(4):1119-30.

19.

Disparate roles for TNF-alpha and Fas ligand in concanavalin A-induced hepatitis.

Ksontini R, Colagiovanni DB, Josephs MD, Edwards CK 3rd, Tannahill CL, Solorzano CC, Norman J, Denham W, Clare-Salzler M, MacKay SL, Moldawer LL.

J Immunol. 1998 Apr 15;160(8):4082-9.

20.

Increased leptin expression in mice with bacterial peritonitis is partially regulated by tumor necrosis factor alpha.

Moshyedi AK, Josephs MD, Abdalla EK, Mackay SL, Edwards CK 3rd, Copeland EM 3rd, Moldawer LL.

Infect Immun. 1998 Apr;66(4):1800-2.

21.

Inhibition of transforming growth factor alpha stimulation of human squamous cell carcinoma of the head and neck with anti-TGF-alpha antibodies and tyrphostin.

Solorzano CC, Jones SC, Pettitjean M, O'Daniel TG, Auffenberg T, Woost PG, Copeland EM 3rd, Moldawer LL, Schultz GS, MacKay SL.

Ann Surg Oncol. 1997 Dec;4(8):670-84.

PMID:
9416416
22.

A matrix metalloproteinase inhibitor prevents processing of tumor necrosis factor alpha (TNF alpha) and abrogates endotoxin-induced lethality.

Solorzano CC, Ksontini R, Pruitt JH, Auffenberg T, Tannahill C, Galardy RE, Schultz GP, MacKay SL, Copeland EM 3rd, Moldawer LL.

Shock. 1997 Jun;7(6):427-31.

PMID:
9185243
23.

Involvement of 26-kDa cell-associated TNF-alpha in experimental hepatitis and exacerbation of liver injury with a matrix metalloproteinase inhibitor.

Solorzano CC, Ksontini R, Pruitt JH, Hess PJ, Edwards PD, Kaibara A, Abouhamze A, Auffenberg T, Galardy RE, Vauthey JN, Copeland EM 3rd, Edwards CK 3rd, Lauwers GY, Clare-Salzler M, MacKay SL, Moldawer LL, Lazarus DD.

J Immunol. 1997 Jan 1;158(1):414-9.

PMID:
8977217
24.

Colon cancer cells that are not growth inhibited by TGF-beta lack functional type I and type II TGF-beta receptors.

MacKay SL, Yaswen LR, Tarnuzzer RW, Moldawer LL, Bland KI, Copeland EM 3rd, Schultz GS.

Ann Surg. 1995 Jun;221(6):767-76; discussion 776-7.

25.
26.

Transcribed heteroplasmic repeated sequences in the porcine mitochondrial DNA D-loop region.

Ghivizzani SC, Mackay SL, Madsen CS, Laipis PJ, Hauswirth WW.

J Mol Evol. 1993 Jul;37(1):36-7.

PMID:
8360917
27.

Detection of transforming growth factor-alpha messenger RNA and protein in human corneal epithelial cells.

Khaw PT, Schultz GS, MacKay SL, Chegini N, Rotatori DS, Adams JL, Shimizu RW.

Invest Ophthalmol Vis Sci. 1992 Nov;33(12):3302-6.

PMID:
1428705
28.

Five-minute treatments with fluorouracil, floxuridine, and mitomycin have long-term effects on human Tenon's capsule fibroblasts.

Khaw PT, Sherwood MB, MacKay SL, Rossi MJ, Schultz G.

Arch Ophthalmol. 1992 Aug;110(8):1150-4.

PMID:
1386726
30.

Effects of benzoyltropine and tropacocaine on several cholinergic processes in the rat brain.

Meyer EM, Potter LT, De Vane CL, Irwin I, MacKay SL, Miller R, Ruttenber AJ.

J Pharmacol Exp Ther. 1990 Aug;254(2):584-90.

PMID:
1974643
31.

Template-directed arrest of mammalian mitochondrial DNA synthesis.

MacKay SL, Olivo PD, Laipis PJ, Hauswirth WW.

Mol Cell Biol. 1986 Apr;6(4):1261-7.

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