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Items: 1 to 50 of 894

1.

GATAD2B-associated neurodevelopmental disorder (GAND): clinical and molecular insights into a NuRD-related disorder.

Shieh C, Jones N, Vanle B, Au M, Huang AY, Silva APG, Lee H, Douine ED, Otero MG, Choi A, Grand K, Taff IP, Delgado MR, Hajianpour MJ, Seeley A, Rohena L, Vernon H, Gripp KW, Vergano SA, Mahida S, Naidu S, Sousa AB, Wain KE, Challman TD, Beek G, Basel D, Ranells J, Smith R, Yusupov R, Freckmann ML, Ohden L, Davis-Keppen L, Chitayat D, Dowling JJ, Finkel R, Dauber A, Spillmann R, Pena LDM, Metcalfe K, Splitt M, Lachlan K, McKee SA, Hurst J, Fitzpatrick DR, Morton JEV, Cox H, Venkateswaran S, Young JI, Marsh ED, Nelson SF, Martinez JA, Graham JM Jr, Kini U, Mackay JP, Pierson TM.

Genet Med. 2020 Jan 17. doi: 10.1038/s41436-019-0747-z. [Epub ahead of print]

PMID:
31949314
2.

Cholix protein domain I functions as a carrier element for efficient apical to basal epithelial transcytosis.

Taverner A, MacKay J, Laurent F, Hunter T, Liu K, Mangat K, Song L, Seto E, Postlethwaite S, Alam A, Chandalia A, Seung M, Saberi M, Feng W, Mrsny RJ.

Tissue Barriers. 2020 Jan 13:1710429. doi: 10.1080/21688370.2019.1710429. [Epub ahead of print]

PMID:
31928299
3.

Nanotoxicology of an elastin-like polypeptide rapamycin formulation for breast cancer.

Peddi S, Roberts SK, MacKay JA.

Biomacromolecules. 2020 Jan 13. doi: 10.1021/acs.biomac.9b01431. [Epub ahead of print]

PMID:
31927993
4.

Hydroxyacetophenone defenses in white spruce against spruce budworm.

Parent GJ, Méndez-Espinoza C, Giguère I, Mageroy MH, Charest M, Bauce É, Bohlmann J, MacKay JJ.

Evol Appl. 2019 Dec 20;13(1):62-75. doi: 10.1111/eva.12885. eCollection 2020 Jan.

5.

Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system.

Werner MT, Wang H, Hamagami N, Hsu SC, Yano JA, Stonestrom AJ, Behera V, Mackay JP, Blobel GA.

J Biol Chem. 2019 Dec 2. pii: jbc.RA119.010679. doi: 10.1074/jbc.RA119.010679. [Epub ahead of print]

6.

A heme-binding protein produced by Haemophilus haemolyticus inhibits non-typeable Haemophilus influenzae.

Latham RD, Torrado M, Atto B, Walshe JL, Wilson R, Guss JM, Mackay JP, Tristram S, Gell DA.

Mol Microbiol. 2019 Nov 19. doi: 10.1111/mmi.14426. [Epub ahead of print]

PMID:
31742788
7.

The NuRD complex and macrocephaly associated neurodevelopmental disorders.

Pierson TM, Otero MG, Grand K, Choi A, Graham JM Jr, Young JI, Mackay JP.

Am J Med Genet C Semin Med Genet. 2019 Dec;181(4):548-556. doi: 10.1002/ajmg.c.31752. Epub 2019 Nov 18.

PMID:
31737996
8.

Study protocol: a randomised non-inferiority trial using interactive virtual presence to remotely assist parents with child restraint installations.

Schwebel DC, MacKay JM, Redden D.

Inj Prev. 2019 Nov 14. pii: injuryprev-2019-043463. doi: 10.1136/injuryprev-2019-043463. [Epub ahead of print]

PMID:
31727672
9.

The humanin peptide mediates ELP nanoassembly and protects human retinal pigment epithelial cells from oxidative stress.

Li Z, Sreekumar PG, Peddi S, Hinton DR, Kannan R, MacKay JA.

Nanomedicine. 2019 Oct 23;24:102111. doi: 10.1016/j.nano.2019.102111. [Epub ahead of print]

PMID:
31655204
10.

Peppy: A virtual reality environment for exploring the principles of polypeptide structure.

Doak DG, Denyer GS, Gerrard JA, Mackay JP, Allison JR.

Protein Sci. 2020 Jan;29(1):157-168. doi: 10.1002/pro.3752. Epub 2019 Nov 11.

PMID:
31622516
11.

Factors influencing implementation of evidence-based interventions in public health systems - a model.

Vincenten J, MacKay JM, Schröder-Bäck P, Schloemer T, Brand H.

Cent Eur J Public Health. 2019 Sep;27(3):198-203. doi: 10.21101/cejph.a5234. Review.

PMID:
31580554
12.

Reply.

Driban JB, Harkey MS, Ward RJ, Lo GH, MacKay JW, McAlindon TE.

Arthritis Rheumatol. 2020 Jan;72(1):198-200. doi: 10.1002/art.41124. Epub 2019 Nov 26. No abstract available.

PMID:
31566933
13.

Synthesis and RNA-Binding Properties of Extended Nucleobases for Triplex-Forming Peptide Nucleic Acids.

Kumpina I, Brodyagin N, MacKay JA, Kennedy SD, Katkevics M, Rozners E.

J Org Chem. 2019 Nov 1;84(21):13276-13298. doi: 10.1021/acs.joc.9b01133. Epub 2019 Oct 2.

PMID:
31538780
14.

Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout.

Bursill D, Taylor WJ, Terkeltaub R, Abhishek A, So AK, Vargas-Santos AB, Gaffo AL, Rosenthal A, Tausche AK, Reginato A, Manger B, Sciré C, Pineda C, van Durme C, Lin CT, Yin C, Albert DA, Biernat-Kaluza E, Roddy E, Pascual E, Becce F, Perez-Ruiz F, Sivera F, Lioté F, Schett G, Nuki G, Filippou G, McCarthy G, da Rocha Castelar Pinheiro G, Ea HK, Tupinambá HA, Yamanaka H, Choi HK, Mackay J, ODell JR, Vázquez Mellado J, Singh JA, Fitzgerald JD, Jacobsson LTH, Joosten L, Harrold LR, Stamp L, Andrés M, Gutierrez M, Kuwabara M, Dehlin M, Janssen M, Doherty M, Hershfield MS, Pillinger M, Edwards NL, Schlesinger N, Kumar N, Slot O, Ottaviani S, Richette P, MacMullan PA, Chapman PT, Lipsky PE, Robinson P, Khanna PP, Gancheva RN, Grainger R, Johnson RJ, Te Kampe R, Keenan RT, Tedeschi SK, Kim S, Choi SJ, Fields TR, Bardin T, Uhlig T, Jansen T, Merriman T, Pascart T, Neogi T, Klück V, Louthrenoo W, Dalbeth N.

Ann Rheum Dis. 2019 Nov;78(11):1592-1600. doi: 10.1136/annrheumdis-2019-215933. Epub 2019 Sep 9.

PMID:
31501138
15.

A new VISION to improve cardiac risk stratification in non-cardiac surgery.

Brand JW, Mackay JH.

Anaesthesia. 2020 Jan;75(1):11-14. doi: 10.1111/anae.14834. Epub 2019 Sep 2. No abstract available.

PMID:
31478188
16.

Teaching best practice in hand hygiene: student use and performance with a gamified gesture recognition system.

Mosley C, Mosley JR, Bell C, Aitchison K, Rhind SM, MacKay J.

Vet Rec. 2019 Oct 12;185(14):444. doi: 10.1136/vr.105338. Epub 2019 Aug 23.

PMID:
31444291
17.

Molecular Targeting of Immunosuppressants Using a Bifunctional Elastin-Like Polypeptide.

Ju Y, Guo H, Yarber F, Edman MC, Peddi S, Janga SR, MacKay JA, Hamm-Alvarez SF.

Bioconjug Chem. 2019 Sep 18;30(9):2358-2372. doi: 10.1021/acs.bioconjchem.9b00462. Epub 2019 Aug 23.

PMID:
31408605
18.

The large repertoire of conifer NLR resistance genes includes drought responsive and highly diversified RNLs.

Van Ghelder C, Parent GJ, Rigault P, Prunier J, Giguère I, Caron S, Stival Sena J, Deslauriers A, Bousquet J, Esmenjaud D, MacKay J.

Sci Rep. 2019 Aug 12;9(1):11614. doi: 10.1038/s41598-019-47950-7.

19.

Acute kidney injury after thoracic surgery: a proposal for a multicentre evaluation (MERITS).

Naruka V, Mckie MA, Khushiwal R, Clayton J, Aresu G, Peryt A, Villar SS, MacKay J, Coonar AS.

Interact Cardiovasc Thorac Surg. 2019 Dec 1;29(6):861-866. doi: 10.1093/icvts/ivz184.

PMID:
31393555
20.

Societal determinants of violent death: The extent to which social, economic, and structural characteristics explain differences in violence across Australia, Canada, and the United States.

Wilkins NJ, Zhang X, Mack KA, Clapperton AJ, Macpherson A, Sleet D, Kresnow-Sedacca MJ, Ballesteros MF, Newton D, Murdoch J, Mackay JM, Berecki-Gisolf J, Marr A, Armstead T, McClure R.

SSM Popul Health. 2019 Jul 8;8:100431. doi: 10.1016/j.ssmph.2019.100431. eCollection 2019 Aug.

21.

New Tobacco Products Do Not Protect Public Health.

Pisinger C, Mackay J.

Ann Am Thorac Soc. 2019 Nov;16(11):1363-1365. doi: 10.1513/AnnalsATS.201905-411PS. No abstract available.

PMID:
31322908
22.

Role of Magnetic Resonance Imaging in Classifying Individuals Who Will Develop Accelerated Radiographic Knee Osteoarthritis.

Price LL, Harkey MS, Ward RJ, MacKay JW, Zhang M, Pang J, Davis JE, McAlindon TE, Lo GH, Amin M, Eaton CB, Lu B, Duryea J, Barbe MF, Driban JB.

J Orthop Res. 2019 Nov;37(11):2420-2428. doi: 10.1002/jor.24413. Epub 2019 Jul 29.

PMID:
31297900
23.

Generation of a Monoclonal Antibody to Detect Elastin-like Polypeptides.

Kouhi A, Yao Z, Zheng L, Li Z, Hu P, Epstein AL, MacKay JA.

Biomacromolecules. 2019 Aug 12;20(8):2942-2952. doi: 10.1021/acs.biomac.9b00503. Epub 2019 Jul 19.

PMID:
31276401
24.

Logistic early warning scores to predict death, cardiac arrest or unplanned intensive care unit re-admission after cardiac surgery.

Chiu YD, Villar SS, Brand JW, Patteril MV, Morrice DJ, Clayton J, Mackay JH.

Anaesthesia. 2020 Feb;75(2):162-170. doi: 10.1111/anae.14755. Epub 2019 Jul 3.

PMID:
31270799
25.

Inhibition of Cathepsin S Reduces Lacrimal Gland Inflammation and Increases Tear Flow in a Mouse Model of Sjögren's Syndrome.

Klinngam W, Janga SR, Lee C, Ju Y, Yarber F, Shah M, Guo H, Wang D, MacKay JA, Edman MC, Hamm-Alvarez SF.

Sci Rep. 2019 Jul 2;9(1):9559. doi: 10.1038/s41598-019-45966-7.

26.

Requirements for improving health and well-being of children with Prader-Willi syndrome and their families.

Mackay J, McCallum Z, Ambler GR, Vora K, Nixon G, Bergman P, Shields N, Milner K, Kapur N, Crock P, Caudri D, Curran J, Verge C, Seton C, Tai A, Tham E, Musthaffa Y, Lafferty AR, Blecher G, Harper J, Schofield C, Nielsen A, Wilson A, Leonard H, Choong CS, Downs J.

J Paediatr Child Health. 2019 Sep;55(9):1029-1037. doi: 10.1111/jpc.14546. Epub 2019 Jun 30. Review.

27.

Accelerated knee osteoarthritis is associated with pre-radiographic degeneration of the extensor mechanism and cruciate ligaments: data from the Osteoarthritis Initiative.

Davis JE, Harkey MS, Ward RJ, MacKay JW, Lu B, Price LL, Eaton CB, Lo GH, Barbe MF, McAlindon TE, Driban JB.

BMC Musculoskelet Disord. 2019 Jun 29;20(1):308. doi: 10.1186/s12891-019-2685-y.

28.

Functional Analysis of the PgCesA3 White Spruce Cellulose Synthase Gene Promoter in Secondary Xylem.

Sena JS, Lachance D, Duval I, Nguyen TTA, Stewart D, Mackay J, Séguin A.

Front Plant Sci. 2019 May 28;10:626. doi: 10.3389/fpls.2019.00626. eCollection 2019.

29.

Early pre-radiographic structural pathology precedes the onset of accelerated knee osteoarthritis.

Harkey MS, Davis JE, Lu B, Price LL, Ward RJ, MacKay JW, Eaton CB, Lo GH, Barbe MF, Zhang M, Pang J, Stout AC, McAlindon TE, Driban JB.

BMC Musculoskelet Disord. 2019 May 22;20(1):241. doi: 10.1186/s12891-019-2624-y.

30.

Berunda Polypeptides: Biheaded Rapamycin Carriers for Subcutaneous Treatment of Autoimmune Dry Eye Disease.

Lee C, Guo H, Klinngam W, Janga SR, Yarber F, Peddi S, Edman MC, Tiwari N, Liu S, Louie SG, Hamm-Alvarez SF, MacKay JA.

Mol Pharm. 2019 Jul 1;16(7):3024-3039. doi: 10.1021/acs.molpharmaceut.9b00263. Epub 2019 May 30.

PMID:
31095909
31.

Thermally-Responsive Loading and Release of Elastin-Like Polypeptides from Contact Lenses.

Wang W, Lee C, Pastuszka M, Laurie GW, MacKay JA.

Pharmaceutics. 2019 May 7;11(5). pii: E221. doi: 10.3390/pharmaceutics11050221.

32.

NPY2 Receptors Reduce Tonic Action Potential-Independent GABAB Currents in the Basolateral Amygdala.

Mackay JP, Bompolaki M, DeJoseph MR, Michaelson SD, Urban JH, Colmers WF.

J Neurosci. 2019 Jun 19;39(25):4909-4930. doi: 10.1523/JNEUROSCI.2226-18.2019. Epub 2019 Apr 10.

33.

The uncharacterized bacterial protein YejG has the same architecture as domain III of elongation factor G.

Mohanty B, Hanson-Manful P, Finn TJ, Chambers CR, McKellar JLO, Macindoe I, Helder S, Setiyaputra S, Zhong Y, Mackay JP, Patrick WM.

Proteins. 2019 Aug;87(8):699-705. doi: 10.1002/prot.25687. Epub 2019 Apr 22.

PMID:
30958578
34.

Identifying Needs for Self-management Interventions for Adults With CKD and Their Caregivers: A Qualitative Study.

Donald M, Beanlands H, Straus S, Ronksley P, Tam-Tham H, Finlay J, MacKay J, Elliott M, Herrington G, Harwood L, Large CA, Large CL, Waldvogel B, Sparkes D, Delgado M, Tong A, Grill A, Novak M, James MT, Brimble KS, Samuel S, Hemmelgarn BR.

Am J Kidney Dis. 2019 Oct;74(4):474-482. doi: 10.1053/j.ajkd.2019.02.006. Epub 2019 Apr 2.

PMID:
30952486
35.

The stoichiometry and interactome of the Nucleosome Remodeling and Deacetylase (NuRD) complex are conserved across multiple cell lines.

Sharifi Tabar M, Mackay JP, Low JKK.

FEBS J. 2019 Jun;286(11):2043-2061. doi: 10.1111/febs.14800. Epub 2019 Mar 19.

PMID:
30828972
36.

Peer-Led Academic Support for Pre-Arrival Students of the BVM&S Degree Program.

Paterson J, Keys C, Phillips K, Yntema M, MacKay JRD.

J Vet Med Educ. 2019 Winter;46(4):481-488. doi: 10.3138/jvme.1017-149r. Epub 2019 Feb 26.

PMID:
30806564
37.

Exploring the suitability of RanBP2-type Zinc Fingers for RNA-binding protein design.

De Franco S, Vandenameele J, Brans A, Verlaine O, Bendak K, Damblon C, Matagne A, Segal DJ, Galleni M, Mackay JP, Vandevenne M.

Sci Rep. 2019 Feb 21;9(1):2484. doi: 10.1038/s41598-019-38655-y.

38.

Field Evaluation of a Binary Sex Pheromone for Sweetpotato Vine Borer (Lepidoptera: Crambidae) in Hawaii.

McQuate GT, Cossé A, Sylva CD, MacKay JA.

J Insect Sci. 2019 Jan 1;19(1). doi: 10.1093/jisesa/iez008.

39.

Synthetic, Structural, and RNA Binding Studies on 2-Aminopyridine-Modified Triplex-Forming Peptide Nucleic Acids.

Kotikam V, Kennedy SD, MacKay JA, Rozners E.

Chemistry. 2019 Mar 21;25(17):4367-4372. doi: 10.1002/chem.201806293. Epub 2019 Mar 4.

PMID:
30746843
40.

Primary care referral for knee MRI in the United Kingdom: Association with demography and subsequent surgical intervention.

Jayaram PR, Sun J, Coombes E, Mackay J, Kasmai B, McNamara I, Jones AP, Denton ERE, Toms AP.

J Magn Reson Imaging. 2019 Jun;49(7):e176-e182. doi: 10.1002/jmri.26560. Epub 2019 Jan 13.

PMID:
30637879
41.

Phenological shifts in conifer species stressed by spruce budworm defoliation.

Deslauriers A, Fournier MP, Cartenì F, Mackay J.

Tree Physiol. 2019 Apr 1;39(4):590-605. doi: 10.1093/treephys/tpy135.

PMID:
30597102
42.

Accelerated Knee Osteoarthritis Is Characterized by Destabilizing Meniscal Tears and Preradiographic Structural Disease Burden.

Driban JB, Davis JE, Lu B, Price LL, Ward RJ, MacKay JW, Eaton CB, Lo GH, Barbe MF, Zhang M, Pang J, Stout AC, Harkey MS, McAlindon TE.

Arthritis Rheumatol. 2019 Jul;71(7):1089-1100. doi: 10.1002/art.40826. Epub 2019 May 21.

PMID:
30592385
43.

Use of Direct Oral Anticoagulants Among Patients Undergoing Cardioversion: The Importance of Timing Before Cardioversion.

Warden BA, MacKay J, Jafari M, Willman A, Stecker EC.

J Am Heart Assoc. 2018 Nov 20;7(22):e010854. doi: 10.1161/JAHA.118.010854. Review. No abstract available.

44.

Crk adaptor proteins mediate actin-dependent T cell migration and mechanosensing induced by the integrin LFA-1.

Roy NH, MacKay JL, Robertson TF, Hammer DA, Burkhardt JK.

Sci Signal. 2018 Dec 11;11(560). pii: eaat3178. doi: 10.1126/scisignal.aat3178.

45.

Diffuse tibiofemoral cartilage change prior to the development of accelerated knee osteoarthritis: Data from the osteoarthritis initiative.

Harkey MS, Davis JE, Lu B, Price LL, Eaton CB, Lo GH, Barbe MF, Ward RJ, Zhang M, Liu SH, Lapane KL, MacKay JW, McAlindon TE, Driban JB.

Clin Anat. 2019 Apr;32(3):369-378. doi: 10.1002/ca.23321. Epub 2018 Dec 26.

46.

A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence.

Lu B, Klingbeil O, Tarumoto Y, Somerville TDD, Huang YH, Wei Y, Wai DC, Low JKK, Milazzo JP, Wu XS, Cao Z, Yan X, Demerdash OE, Huang G, Mackay JP, Kinney JB, Shi J, Vakoc CR.

Cancer Cell. 2018 Dec 10;34(6):970-981.e8. doi: 10.1016/j.ccell.2018.10.015. Epub 2018 Nov 29.

47.

Intracellular Delivery of Rapamycin From FKBP Elastin-Like Polypeptides Is Consistent With Macropinocytosis.

Peddi S, Pan X, MacKay JA.

Front Pharmacol. 2018 Oct 17;9:1184. doi: 10.3389/fphar.2018.01184. eCollection 2018.

48.

A novel elastin-like polypeptide drug carrier for cyclosporine A improves tear flow in a mouse model of Sjögren's syndrome.

Guo H, Lee C, Shah M, Janga SR, Edman MC, Klinngam W, Hamm-Alvarez SF, MacKay JA.

J Control Release. 2018 Dec 28;292:183-195. doi: 10.1016/j.jconrel.2018.10.026. Epub 2018 Oct 23.

49.

Effusion-synovitis and infrapatellar fat pad signal intensity alteration differentiate accelerated knee osteoarthritis.

Davis JE, Ward RJ, MacKay JW, Lu B, Price LL, McAlindon TE, Eaton CB, Barbe MF, Lo GH, Harkey MS, Driban JB.

Rheumatology (Oxford). 2019 Mar 1;58(3):418-426. doi: 10.1093/rheumatology/key305.

50.

PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex.

Link S, Spitzer RMM, Sana M, Torrado M, Völker-Albert MC, Keilhauer EC, Burgold T, Pünzeler S, Low JKK, Lindström I, Nist A, Regnard C, Stiewe T, Hendrich B, Imhof A, Mann M, Mackay JP, Bartkuhn M, Hake SB.

Nat Commun. 2018 Oct 16;9(1):4300. doi: 10.1038/s41467-018-06665-5.

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