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Items: 1 to 50 of 54

1.

Characterising covalent warhead reactivity.

Martin JS, MacKenzie CJ, Fletcher D, Gilbert IH.

Bioorg Med Chem. 2019 May 15;27(10):2066-2074. doi: 10.1016/j.bmc.2019.04.002. Epub 2019 Apr 3.

2.

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis.

Thomas MG, De Rycker M, Ajakane M, Albrecht S, Álvarez-Pedraglio AI, Boesche M, Brand S, Campbell L, Cantizani-Perez J, Cleghorn LAT, Copley RCB, Crouch SD, Daugan A, Drewes G, Ferrer S, Ghidelli-Disse S, Gonzalez S, Gresham SL, Hill AP, Hindley SJ, Lowe RM, MacKenzie CJ, MacLean L, Manthri S, Martin F, Miguel-Siles J, Nguyen VL, Norval S, Osuna-Cabello M, Woodland A, Patterson S, Pena I, Quesada-Campos MT, Reid IH, Revill C, Riley J, Ruiz-Gomez JR, Shishikura Y, Simeons FRC, Smith A, Smith VC, Spinks D, Stojanovski L, Thomas J, Thompson S, Underwood T, Gray DW, Fiandor JM, Gilbert IH, Wyatt PG, Read KD, Miles TJ.

J Med Chem. 2019 Feb 14;62(3):1180-1202. doi: 10.1021/acs.jmedchem.8b01218. Epub 2018 Dec 20.

3.

Detection of equine coronavirus in horses in the United Kingdom.

Bryan J, Marr CM, Mackenzie CJ, Mair TS, Fletcher A, Cash R, Phillips M, Pusterla N, Mapes S, Foote AK.

Vet Rec. 2019 Jan 26;184(4):123. doi: 10.1136/vr.105098. Epub 2018 Dec 7. No abstract available.

PMID:
30530800
4.

Comparison of two blood sampling techniques for the determination of coagulation parameters in the horse: Jugular venipuncture and indwelling intravenous catheter.

Mackenzie CJ, McGowan CM, Pinchbeck G, Carslake HB.

Equine Vet J. 2018 May;50(3):333-338. doi: 10.1111/evj.12764. Epub 2017 Nov 2.

PMID:
28976034
5.

Correction for Arora et al., "Respiratory Flexibility in Response to Inhibition of Cytochrome c Oxidase in Mycobacterium tuberculosis".

Arora K, Ochoa-Montaño B, Tsang PS, Blundell TL, Dawes SS, Mizrahi V, Bayliss T, Mackenzie CJ, Cleghorn LAT, Ray PC, Wyatt PG, Uh E, Lee J, Barry CE 3rd, Boshoff HI.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e01429-17. doi: 10.1128/AAC.01429-17. Print 2017 Sep. No abstract available.

6.

Ultrasonographic assessment of the atlanto-occipital space in healthy Thoroughbred foals and Thoroughbred foals with neonatal maladjustment syndrome.

Mackenzie CJ, Haggett EF, Pinchbeck GL, Marr CM.

Vet J. 2017 May;223:55-59. doi: 10.1016/j.tvjl.2017.04.002. Epub 2017 May 2.

PMID:
28671073
7.

Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis.

Park Y, Pacitto A, Bayliss T, Cleghorn LA, Wang Z, Hartman T, Arora K, Ioerger TR, Sacchettini J, Rizzi M, Donini S, Blundell TL, Ascher DB, Rhee K, Breda A, Zhou N, Dartois V, Jonnala SR, Via LE, Mizrahi V, Epemolu O, Stojanovski L, Simeons F, Osuna-Cabello M, Ellis L, MacKenzie CJ, Smith AR, Davis SH, Murugesan D, Buchanan KI, Turner PA, Huggett M, Zuccotto F, Rebollo-Lopez MJ, Lafuente-Monasterio MJ, Sanz O, Diaz GS, Lelièvre J, Ballell L, Selenski C, Axtman M, Ghidelli-Disse S, Pflaumer H, Bösche M, Drewes G, Freiberg GM, Kurnick MD, Srikumaran M, Kempf DJ, Green SR, Ray PC, Read K, Wyatt P, Barry CE 3rd, Boshoff HI.

ACS Infect Dis. 2017 Jan 13;3(1):18-33. doi: 10.1021/acsinfecdis.6b00103. Epub 2016 Oct 17.

8.

Episcleral cyclosporine A implants for the management of unilateral keratoconjunctivitis sicca in an 8-year-old mare.

Mackenzie CJ, Carslake HB, Robin M, Kent RJ, Malalana F.

Vet Ophthalmol. 2017 Jan;20(1):79-83. doi: 10.1111/vop.12368. Epub 2016 Mar 4.

PMID:
26945681
9.

Respiratory flexibility in response to inhibition of cytochrome C oxidase in Mycobacterium tuberculosis.

Arora K, Ochoa-Montaño B, Tsang PS, Blundell TL, Dawes SS, Mizrahi V, Bayliss T, Mackenzie CJ, Cleghorn LA, Ray PC, Wyatt PG, Uh E, Lee J, Barry CE 3rd, Boshoff HI.

Antimicrob Agents Chemother. 2014 Nov;58(11):6962-5. doi: 10.1128/AAC.03486-14. Epub 2014 Aug 25. Erratum in: Antimicrob Agents Chemother. 2017 Aug 24;61(9):.

10.

COS-1 cells as packaging host for production of lentiviruses.

MacKenzie CJ, Shioda T.

Curr Protoc Cell Biol. 2011 Mar;Chapter 26:Unit 26.7. doi: 10.1002/0471143030.cb2607s50.

PMID:
21400698
11.

Influence of the mother's preceding pregnancies on fetal development and postnatal survival of the neonate, in normal pregnancy. An immunological phenomenon?

Vernier MC, Mackenzie CJ, Schulzer M, Vernier PR.

Am J Hum Biol. 2010 Sep-Oct;22(5):708-15. doi: 10.1002/ajhb.21071.

PMID:
20737621
12.

Neurotrophic actions of PACAP-38 and LIF on human neuroblastoma SH-SY5Y cells.

Monaghan TK, Pou C, MacKenzie CJ, Plevin R, Lutz EM.

J Mol Neurosci. 2008 Nov;36(1-3):45-56. doi: 10.1007/s12031-008-9082-6. Epub 2008 May 28.

PMID:
18506635
13.

PACAP-38 induces neuronal differentiation of human SH-SY5Y neuroblastoma cells via cAMP-mediated activation of ERK and p38 MAP kinases.

Monaghan TK, Mackenzie CJ, Plevin R, Lutz EM.

J Neurochem. 2008 Jan;104(1):74-88. Epub 2007 Nov 6.

14.

IKKalpha and IKKbeta function in TNFalpha-stimulated adhesion molecule expression in human aortic smooth muscle cells.

MacKenzie CJ, Ritchie E, Paul A, Plevin R.

Cell Signal. 2007 Jan;19(1):75-80. Epub 2006 Jul 26.

PMID:
16872805
16.

Additional signals from VPAC/PAC family receptors.

McCulloch DA, MacKenzie CJ, Johnson MS, Robertson DN, Holland PJ, Ronaldson E, Lutz EM, Mitchell R.

Biochem Soc Trans. 2002 Aug;30(4):441-6. Review.

PMID:
12196111
18.
19.

ADP-ribosylation factor-dependent phospholipase D activation by VPAC receptors and a PAC(1) receptor splice variant.

McCulloch DA, Lutz EM, Johnson MS, Robertson DN, MacKenzie CJ, Holland PJ, Mitchell R.

Mol Pharmacol. 2001 Jun;59(6):1523-32.

PMID:
11353814
20.

Differential activation of phospholipase D by VPAC and PAC1 receptors.

McCulloch DA, Lutz EM, Johnson MS, MacKenzie CJ, Mitchell R.

Ann N Y Acad Sci. 2000;921:175-85.

PMID:
11193821
21.

Mechanisms of phospholipase C activation by the vasoactive intestinal polypeptide/pituitary adenylate cyclase-activating polypeptide type 2 receptor.

MacKenzie CJ, Lutz EM, Johnson MS, Robertson DN, Holland PJ, Mitchell R.

Endocrinology. 2001 Mar;142(3):1209-17.

PMID:
11181537
22.

Regulation of glucose transport in aortic smooth muscle cells by cAMP and cGMP.

MacKenzie CJ, Wakefield JM, Cairns F, Dominiczak AF, Gould GW.

Biochem J. 2001 Feb 1;353(Pt 3):513-9.

23.

Gonadotropin-releasing hormone receptor activation of extracellular signal-regulated kinase and tyrosine kinases in transfected GH3 cells and in alphaT3-1 cells.

Johnson MS, Lutz EM, MacKenzie CJ, Wolbers WB, Robertson DN, Holland PJ, Mitchell R.

Endocrinology. 2000 Sep;141(9):3087-97.

PMID:
10965878
24.

Domains determining agonist selectivity in chimaeric VIP2 (VPAC2)/PACAP (PAC1) receptors.

Lutz EM, MacKenzie CJ, Johnson M, West K, Morrow JA, Harmar AJ, Mitchell R.

Br J Pharmacol. 1999 Oct;128(4):934-40.

25.

Phospholipase C activation by VIP1 and VIP2 receptors expressed in COS 7 cells involves a pertussis toxin-sensitive mechanism.

MacKenzie CJ, Lutz EM, McCulloch DA, Mitchell R, Harmar AJ.

Ann N Y Acad Sci. 1996 Dec 26;805:579-84. No abstract available.

PMID:
8993443
26.

Chimaeric VIP2/PACAP receptors reveal that agonist pharmacology but not signal transduction is determined by extracellular domain 1.

Lutz EM, MacKenzie CJ, Morrow J, Mitchell R, Bennie J, Carroll S, Clark E, Harmar AJ.

Ann N Y Acad Sci. 1996 Dec 26;805:574-8. No abstract available.

PMID:
8993442
27.

Incidence and classification of early embryonic mortality in broiler breeder chickens.

Scott TA, Mackenzie CJ.

Br Poult Sci. 1993 Jul;34(3):459-70.

PMID:
8358633
28.

Longitudinal study of vibration-induced white finger among coastal fallers in British Columbia.

Brubaker RL, Mackenzie CJ, Hertzman C, Hutton SG, Slakov J.

Scand J Work Environ Health. 1987 Aug;13(4):305-8.

29.

Blood lead and carboxyhemoglobin levels in chainsaw operators.

van Netten C, Brubaker RL, Mackenzie CJ, Godolphin WJ.

Environ Res. 1987 Jun;43(1):244-50.

PMID:
3582311
30.

Vibration-induced white finger among selected underground rock drillers in British Columbia.

Brubaker RL, Mackenzie CJ, Hutton SG.

Scand J Work Environ Health. 1986 Aug;12(4 Spec No):296-300.

31.

Pathogenic hazards and public spa and hot tub facilities.

Crandall RA, MacKenzie CJ.

Can J Public Health. 1984 May-Jun;75(3):223-6. No abstract available.

PMID:
6744193
32.

Two examples of environmental problems occurring in remote sparsely populated areas.

Mackenzie CJ, Kyle JH.

Ann Acad Med Singapore. 1984 Apr;13(2):237-46.

PMID:
6497321
33.

Vibration white finger disease among tree fellers in British columbia.

Brubaker RL, Mackenzie CJ, Eng PR, Bates DV.

J Occup Med. 1983 May;25(5):403-8.

PMID:
6854430
34.

Community medicine: education and practice.

Mackenzie CJ.

P N G Med J. 1983 Mar;26(1):48-54.

PMID:
6585101
35.

Albuminuria at Lake Murray due to high methylmercury intake.

Kyle JH, Mackenzie CJ.

P N G Med J. 1982 Dec;25(4):227-9.

PMID:
6964015
36.

Environmental lead and young children.

Mackenzie CJ.

Can Med Assoc J. 1981 Jan 15;124(2):124. No abstract available.

37.

Detection of incipient effects of anticholinesterase insecticides in rats and humans by electromyography and cholinesterase assay.

Hussain MA, Oloffs PC, Blatherwick FJ, Gaunce AP, MacKenzie CJ.

J Environ Sci Health B. 1981;16(1):1-19.

PMID:
7204881
38.

CPHA study tour to the People's Republic of China, July 1980.

MacKenzie CJ.

Can J Public Health. 1980 Sep-Oct;71(5):313-20. No abstract available.

PMID:
7448686
39.

Environmental lead and young children.

Mackenzie CJ.

Can Med Assoc J. 1980 Jun 21;122(12):1347-8. No abstract available.

40.

Weight-height relationship and the effect of self-assessed frame in Health Hazard Appraisal.

Laszlo CA, Milsum JH, Varga L, MacKenzie CJ.

Can J Public Health. 1980 May-Jun;71(3):181-9. No abstract available.

PMID:
7417915
41.

Economic development-boon or hazard to public health?

Mackenzie CJ.

Can J Public Health. 1979 Jan-Feb;70(1):34-7. No abstract available.

PMID:
421168
42.

Letter: Malaria prophylaxis.

Mackenzie CJ, Wyatt G.

JAMA. 1976 Sep 6;236(10):1114-5. No abstract available.

PMID:
988861
43.

Critical requirements in regional health planning.

Meekison WG, Mackenzie CJ, Fraser B.

Can J Public Health. 1975 Jul-Aug;66(4):299-306. No abstract available.

PMID:
1156992
45.

An analysis of the practice of four physicians in british columbia-1961-1962.

Mackenzie CJ, Coleman JU, Postuk P.

Can Fam Physician. 1969 Jan;15(1):51-60. No abstract available.

46.

The Vancouver family planning clinic: a comparison of two years' experience.

Mackenzie CJ.

Can J Public Health. 1968 Jul;59(7):257-65. No abstract available.

PMID:
5667779
47.

Diphtheria and typhoid.

Mackenzie CJ.

Appl Ther. 1967 Jun;9(6):545. No abstract available.

PMID:
5338369
48.

The Vancouver Family Planning Clinic: a case study.

Mackenzie CJ, Evans GP, Peck JG.

Can J Public Health. 1967 Feb;58(2):53-60. No abstract available.

PMID:
6044918
49.
50.

Society, sociology and health.

Mackenzie CJ.

Can Nurse. 1965 Nov;61(11):896-8. No abstract available.

PMID:
5840291

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