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Items: 48


CCR2 mediates the adverse effects of LPS in the pregnant mouse.

Hua R, Edey LF, O'Dea KP, Howe L, Herbert BR, Cheng W, Zheng X, MacIntyre DA, Bennett PR, Takata M, Johnson MR.

Biol Reprod. 2019 Oct 10. pii: ioz188. doi: 10.1093/biolre/ioz188. [Epub ahead of print]


The association between vaginal bacterial composition and miscarriage: a nested case-control study.

Al-Memar M, Bobdiwala S, Fourie H, Manino R, Lee YS, Smith A, Marchesi JR, Timmerman D, Bourne T, Bennett PR, MacIntyre DA.

BJOG. 2019 Oct 1. doi: 10.1111/1471-0528.15972. [Epub ahead of print]


The vaginal microbiome in uterine transplantation.

Jones BP, Saso S, L'Heveder A, Bracewell-Milnes T, Thum MY, Diaz-Garcia C, MacIntyre DA, Quiroga I, Ghaem-Maghami S, Testa G, Johannesson L, Bennett PR, Yazbek J, Smith JR.

BJOG. 2019 Aug 8. doi: 10.1111/1471-0528.15881. [Epub ahead of print] Review.


First Trimester Circulating MicroRNA Biomarkers Predictive of Subsequent Preterm Delivery and Cervical Shortening.

Cook J, Bennett PR, Kim SH, Teoh TG, Sykes L, Kindinger LM, Garrett A, Binkhamis R, MacIntyre DA, Terzidou V.

Sci Rep. 2019 Apr 10;9(1):5861. doi: 10.1038/s41598-019-42166-1.


Prospective observational study of vaginal microbiota pre- and post-rescue cervical cerclage.

Brown RG, Chan D, Terzidou V, Lee YS, Smith A, Marchesi JR, MacIntyre DA, Bennett PR.

BJOG. 2019 Jun;126(7):916-925. doi: 10.1111/1471-0528.15600. Epub 2019 Mar 10.


Establishment of vaginal microbiota composition in early pregnancy and its association with subsequent preterm prelabor rupture of the fetal membranes.

Brown RG, Al-Memar M, Marchesi JR, Lee YS, Smith A, Chan D, Lewis H, Kindinger L, Terzidou V, Bourne T, Bennett PR, MacIntyre DA.

Transl Res. 2019 May;207:30-43. doi: 10.1016/j.trsl.2018.12.005. Epub 2018 Dec 27.


Association Between Prepregnancy Cardiovascular Function and Subsequent Preeclampsia or Fetal Growth Restriction.

Foo FL, Mahendru AA, Masini G, Fraser A, Cacciatore S, MacIntyre DA, McEniery CM, Wilkinson IB, Bennett PR, Lees CC.

Hypertension. 2018 Aug;72(2):442-450. doi: 10.1161/HYPERTENSIONAHA.118.11092. Epub 2018 Jul 2.


Assessment of microbiota:host interactions at the vaginal mucosa interface.

Pruski P, Lewis HV, Lee YS, Marchesi JR, Bennett PR, Takats Z, MacIntyre DA.

Methods. 2018 Oct 1;149:74-84. doi: 10.1016/j.ymeth.2018.04.022. Epub 2018 Apr 27. Review.


Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin.

Brown RG, Marchesi JR, Lee YS, Smith A, Lehne B, Kindinger LM, Terzidou V, Holmes E, Nicholson JK, Bennett PR, MacIntyre DA.

BMC Med. 2018 Jan 24;16(1):9. doi: 10.1186/s12916-017-0999-x.


Urinary Metabolic Phenotyping of Women with Lower Urinary Tract Symptoms.

Bray R, Cacciatore S, Jiménez B, Cartwright R, Digesu A, Fernando R, Holmes E, Nicholson JK, Bennett PR, MacIntyre DA, Khullar V.

J Proteome Res. 2017 Nov 3;16(11):4208-4216. doi: 10.1021/acs.jproteome.7b00568. Epub 2017 Oct 4.


Comparison of vaginal microbiota sampling techniques: cytobrush versus swab.

Mitra A, MacIntyre DA, Mahajan V, Lee YS, Smith A, Marchesi JR, Lyons D, Bennett PR, Kyrgiou M.

Sci Rep. 2017 Aug 29;7(1):9802. doi: 10.1038/s41598-017-09844-4.


Medical Swab Analysis Using Desorption Electrospray Ionization Mass Spectrometry: A Noninvasive Approach for Mucosal Diagnostics.

Pruski P, MacIntyre DA, Lewis HV, Inglese P, Correia GD, Hansel TT, Bennett PR, Holmes E, Takats Z.

Anal Chem. 2017 Feb 7;89(3):1540-1550. doi: 10.1021/acs.analchem.6b03405. Epub 2017 Jan 11.


The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk.

Kindinger LM, Bennett PR, Lee YS, Marchesi JR, Smith A, Cacciatore S, Holmes E, Nicholson JK, Teoh TG, MacIntyre DA.

Microbiome. 2017 Jan 19;5(1):6. doi: 10.1186/s40168-016-0223-9.


KODAMA: an R package for knowledge discovery and data mining.

Cacciatore S, Tenori L, Luchinat C, Bennett PR, MacIntyre DA.

Bioinformatics. 2017 Feb 15;33(4):621-623. doi: 10.1093/bioinformatics/btw705.


Preterm Birth Prevention Post-Conization: A Model of Cervical Length Screening with Targeted Cerclage.

Kindinger LM, Kyrgiou M, MacIntyre DA, Cacciatore S, Yulia A, Cook J, Terzidou V, Teoh TG, Bennett PR.

PLoS One. 2016 Nov 3;11(11):e0163793. doi: 10.1371/journal.pone.0163793. eCollection 2016.


The vaginal microbiota, human papillomavirus infection and cervical intraepithelial neoplasia: what do we know and where are we going next?

Mitra A, MacIntyre DA, Marchesi JR, Lee YS, Bennett PR, Kyrgiou M.

Microbiome. 2016 Nov 1;4(1):58. Review.


The Local and Systemic Immune Response to Intrauterine LPS in the Prepartum Mouse.

Edey LF, O'Dea KP, Herbert BR, Hua R, Waddington SN, MacIntyre DA, Bennett PR, Takata M, Johnson MR.

Biol Reprod. 2016 Dec;95(6):125. Epub 2016 Oct 19.


Relationship between vaginal microbial dysbiosis, inflammation, and pregnancy outcomes in cervical cerclage.

Kindinger LM, MacIntyre DA, Lee YS, Marchesi JR, Smith A, McDonald JA, Terzidou V, Cook JR, Lees C, Israfil-Bayli F, Faiza Y, Toozs-Hobson P, Slack M, Cacciatore S, Holmes E, Nicholson JK, Teoh TG, Bennett PR.

Sci Transl Med. 2016 Aug 3;8(350):350ra102. doi: 10.1126/scitranslmed.aag1026.


Modeling hormonal and inflammatory contributions to preterm and term labor using uterine temporal transcriptomics.

Migale R, MacIntyre DA, Cacciatore S, Lee YS, Hagberg H, Herbert BR, Johnson MR, Peebles D, Waddington SN, Bennett PR.

BMC Med. 2016 Jun 13;14(1):86. doi: 10.1186/s12916-016-0632-4.


The oxytocin receptor antagonist, Atosiban, activates pro-inflammatory pathways in human amnion via G(αi) signalling.

Kim SH, MacIntyre DA, Hanyaloglu AC, Blanks AM, Thornton S, Bennett PR, Terzidou V.

Mol Cell Endocrinol. 2016 Jan 15;420:11-23. doi: 10.1016/j.mce.2015.11.012. Epub 2015 Nov 14.


Cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversity.

Mitra A, MacIntyre DA, Lee YS, Smith A, Marchesi JR, Lehne B, Bhatia R, Lyons D, Paraskevaidis E, Li JV, Holmes E, Nicholson JK, Bennett PR, Kyrgiou M.

Sci Rep. 2015 Nov 17;5:16865. doi: 10.1038/srep16865.


Sulfasalazine augments a pro-inflammatory response in interleukin-1β-stimulated amniocytes and myocytes.

Sykes L, Thomson KR, Boyce EJ, Lee YS, Rasheed ZB, MacIntyre DA, Teoh TG, Bennett PR.

Immunology. 2015 Dec;146(4):630-44. doi: 10.1111/imm.12534. Epub 2015 Nov 3.


The effect of gestational age and cervical length measurements in the prediction of spontaneous preterm birth in twin pregnancies: an individual patient level meta-analysis.

Kindinger LM, Poon LC, Cacciatore S, MacIntyre DA, Fox NS, Schuit E, Mol BW, Liem S, Lim AC, Serra V, Perales A, Hermans F, Darzi A, Bennett P, Nicolaides KH, Teoh TG.

BJOG. 2016 May;123(6):877-84. doi: 10.1111/1471-0528.13575. Epub 2015 Sep 1. Review.


Specific Lipopolysaccharide Serotypes Induce Differential Maternal and Neonatal Inflammatory Responses in a Murine Model of Preterm Labor.

Migale R, Herbert BR, Lee YS, Sykes L, Waddington SN, Peebles D, Hagberg H, Johnson MR, Bennett PR, MacIntyre DA.

Am J Pathol. 2015 Sep;185(9):2390-401. doi: 10.1016/j.ajpath.2015.05.015. Epub 2015 Jul 26.


Specific inhibition of c-Jun N-terminal kinase delays preterm labour and reduces mortality.

Pirianov G, MacIntyre DA, Lee Y, Waddington SN, Terzidou V, Mehmet H, Bennett PR.

Reproduction. 2015 Oct;150(4):269-77. doi: 10.1530/REP-15-0258. Epub 2015 Jul 16.


The vaginal microbiome during pregnancy and the postpartum period in a European population.

MacIntyre DA, Chandiramani M, Lee YS, Kindinger L, Smith A, Angelopoulos N, Lehne B, Arulkumaran S, Brown R, Teoh TG, Holmes E, Nicoholson JK, Marchesi JR, Bennett PR.

Sci Rep. 2015 Mar 11;5:8988. doi: 10.1038/srep08988.


Exogenous oxytocin modulates human myometrial microRNAs.

Cook JR, MacIntyre DA, Samara E, Kim SH, Singh N, Johnson MR, Bennett PR, Terzidou V.

Am J Obstet Gynecol. 2015 Jul;213(1):65.e1-65.e9. doi: 10.1016/j.ajog.2015.03.015. Epub 2015 Mar 7.


Oxytocin activates NF-κB-mediated inflammatory pathways in human gestational tissues.

Kim SH, MacIntyre DA, Firmino Da Silva M, Blanks AM, Lee YS, Thornton S, Bennett PR, Terzidou V.

Mol Cell Endocrinol. 2015 Mar 5;403:64-77. doi: 10.1016/j.mce.2014.11.008. Epub 2014 Nov 14.


Calcium channel blockers are effective as first line for tocolysis in the management of preterm labour.

Brown RG, MacIntyre DA.

Evid Based Med. 2014 Dec;19(6):214. doi: 10.1136/ebmed-2014-110063. Epub 2014 Aug 27. No abstract available.


Anti-inflammatory prostaglandins for the prevention of preterm labour.

Sykes L, MacIntyre DA, Teoh TG, Bennett PR.

Reproduction. 2014 Aug;148(2):R29-40. doi: 10.1530/REP-13-0587. Epub 2014 Jun 2. Review.


Activator protein 1 is a key terminal mediator of inflammation-induced preterm labor in mice.

MacIntyre DA, Lee YS, Migale R, Herbert BR, Waddington SN, Peebles D, Hagberg H, Johnson MR, Bennett PR.

FASEB J. 2014 May;28(5):2358-68. doi: 10.1096/fj.13-247783. Epub 2014 Feb 4.


The CRTH2 agonist Pyl A prevents lipopolysaccharide-induced fetal death but induces preterm labour.

Sykes L, Herbert BR, Macintyre DA, Hunte E, Ponnampalam S, Johnson MR, Teoh TG, Bennett PR.

Immunology. 2013 Jul;139(3):352-65. doi: 10.1111/imm.12085.


Chemoattractant receptor homologous to the T helper 2 cell (CRTH2) is not expressed in human amniocytes and myocytes.

Sykes L, Lee Y, Khanjani S, Macintyre DA, Yap XJ, Ponnampalam S, Teoh TG, Bennett PR.

PLoS One. 2012;7(11):e50734. doi: 10.1371/journal.pone.0050734. Epub 2012 Nov 30.


The Th1:th2 dichotomy of pregnancy and preterm labour.

Sykes L, MacIntyre DA, Yap XJ, Teoh TG, Bennett PR.

Mediators Inflamm. 2012;2012:967629. doi: 10.1155/2012/967629. Epub 2012 Jun 7. Review.


Changes in the Th1:Th2 cytokine bias in pregnancy and the effects of the anti-inflammatory cyclopentenone prostaglandin 15-deoxy-Δ(12,14)-prostaglandin J2.

Sykes L, MacIntyre DA, Yap XJ, Ponnampalam S, Teoh TG, Bennett PR.

Mediators Inflamm. 2012;2012:416739. doi: 10.1155/2012/416739. Epub 2012 May 29.


Nuclear factor kappa B activation occurs in the amnion prior to labour onset and modulates the expression of numerous labour associated genes.

Lim S, MacIntyre DA, Lee YS, Khanjani S, Terzidou V, Teoh TG, Bennett PR.

PLoS One. 2012;7(4):e34707. doi: 10.1371/journal.pone.0034707. Epub 2012 Apr 2.


Prevention of preterm labour via the modulation of inflammatory pathways.

MacIntyre DA, Sykes L, Teoh TG, Bennett PR.

J Matern Fetal Neonatal Med. 2012 Apr;25 Suppl 1:17-20. doi: 10.3109/14767058.2012.666114. Epub 2012 Mar 13. Review.


Characterisation of human embryonic stem cells conditioning media by 1H-nuclear magnetic resonance spectroscopy.

MacIntyre DA, Melguizo Sanchís D, Jiménez B, Moreno R, Stojkovic M, Pineda-Lucena A.

PLoS One. 2011 Feb 9;6(2):e16732. doi: 10.1371/journal.pone.0016732.


Serum metabolic signature of minimal hepatic encephalopathy by (1)H-nuclear magnetic resonance.

Jiménez B, Montoliu C, MacIntyre DA, Serra MA, Wassel A, Jover M, Romero-Gomez M, Rodrigo JM, Pineda-Lucena A, Felipo V.

J Proteome Res. 2010 Oct 1;9(10):5180-7. doi: 10.1021/pr100486e.


Serum metabolome analysis by 1H-NMR reveals differences between chronic lymphocytic leukaemia molecular subgroups.

MacIntyre DA, Jiménez B, Lewintre EJ, Martín CR, Schäfer H, Ballesteros CG, Mayans JR, Spraul M, García-Conde J, Pineda-Lucena A.

Leukemia. 2010 Apr;24(4):788-97. doi: 10.1038/leu.2009.295. Epub 2010 Jan 21.


Spontaneous and induced labour are associated with different myometrial proteomes in the human.

MacIntyre DA, Smith R, Yeo G, Kwek K, Bisits AM, Chan EC.

Proteomics Clin Appl. 2009 Mar;3(3):288-98. doi: 10.1002/prca.200800050.


Evidence that a protein kinase A substrate, small heat-shock protein 20, modulates myometrial relaxation in human pregnancy.

Tyson EK, Macintyre DA, Smith R, Chan EC, Read M.

Endocrinology. 2008 Dec;149(12):6157-65. doi: 10.1210/en.2008-0593. Epub 2008 Aug 28.


Adolescent pneumopericardium and pneumomediastinum after motor vehicle crash and ejection.

Markarian MK, MacIntyre DA, Cousins BJ, Fildes JJ, Malone A.

Am J Emerg Med. 2008 May;26(4):515.e1-2. doi: 10.1016/j.ajem.2007.08.008.


Contraction in human myometrium is associated with changes in small heat shock proteins.

MacIntyre DA, Tyson EK, Read M, Smith R, Yeo G, Kwek K, Chan EC.

Endocrinology. 2008 Jan;149(1):245-52. Epub 2007 Oct 4.


Progesterone receptor or cytoskeletal protein?

Madsen G, Macintyre DA, Mesiano S, Smith R.

Reprod Sci. 2007 Apr;14(3):217-22.


Differential enrichment of high- and low-molecular weight proteins and concurrent RNA extraction.

MacIntyre DA, Smith R, Chan EC.

Anal Biochem. 2006 Dec 15;359(2):274-6. Epub 2006 Aug 22. No abstract available. Erratum in: Anal Biochem. 2007 May 1;364(1):95.


The identification of mouse sperm-surface-associated proteins and characterization of their ability to act as decapacitation factors.

Nixon B, MacIntyre DA, Mitchell LA, Gibbs GM, O'Bryan M, Aitken RJ.

Biol Reprod. 2006 Feb;74(2):275-87. Epub 2005 Oct 12.


Response to atmospheric humidity at comfortable air temperature: a comparison of three experiments.

MacIntyre DA.

Ann Occup Hyg. 1978 Aug;21(2):177-90. No abstract available.


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