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Reduced cerebrovascular reactivity among adolescents with bipolar disorder.

Urback AL, Metcalfe AW, Korczak DJ, MacIntosh BJ, Goldstein BI.

Bipolar Disord. 2018 Nov 13. doi: 10.1111/bdi.12719. [Epub ahead of print]


Attention-Related Brain Activation Is Altered in Older Adults With White Matter Hyperintensities Using Multi-Echo fMRI.

Atwi S, Metcalfe AWS, Robertson AD, Rezmovitz J, Anderson ND, MacIntosh BJ.

Front Neurosci. 2018 Oct 18;12:748. doi: 10.3389/fnins.2018.00748. eCollection 2018.


Cortical Volume and Thickness Across Bipolar Disorder Subtypes in Adolescents: A Preliminary Study.

Toma S, Islam AH, Metcalfe AWS, Mitchell RHB, Fiksenbaum L, MacIntosh BJ, Goldstein BI.

J Child Adolesc Psychopharmacol. 2018 Oct 25. doi: 10.1089/cap.2017.0137. [Epub ahead of print]


Cerebrovascular Reactivity during Prolonged Breath-Hold in Experienced Freedivers.

Keil VC, Eichhorn L, Mutsaerts HJMM, Träber F, Block W, Mädler B, van de Ven K, Siero JCW, MacIntosh BJ, Petr J, Fimmers R, Schild HH, Hattingen E.

AJNR Am J Neuroradiol. 2018 Oct;39(10):1839-1847. doi: 10.3174/ajnr.A5790. Epub 2018 Sep 20.


Cerebral blood flow in bipolar disorder: A systematic review.

Toma S, MacIntosh BJ, Swardfager W, Goldstein BI.

J Affect Disord. 2018 Dec 1;241:505-513. doi: 10.1016/j.jad.2018.08.040. Epub 2018 Aug 11. Review.


Brain tissue pulsatility is related to clinical features of Parkinson's disease.

Shirzadi Z, Robertson AD, Metcalfe AW, Duff-Canning S, Marras C, Lang AE, Masellis M, MacIntosh BJ.

Neuroimage Clin. 2018 Jul 23;20:222-227. doi: 10.1016/j.nicl.2018.07.017. eCollection 2018.


Sex differences in brain structure among adolescents with bipolar disorder.

Mitchell RH, Metcalfe AW, Islam AH, Toma S, Patel R, Fiksenbaum L, Korczak D, MacIntosh BJ, Goldstein BI.

Bipolar Disord. 2018 Jun 28. doi: 10.1111/bdi.12663. [Epub ahead of print]


Magnetic resonance imaging of cerebrovascular reactivity in healthy adolescents.

Urback AL, Metcalfe AWS, Korczak DJ, MacIntosh BJ, Goldstein BI.

J Neurosci Methods. 2018 Aug 1;306:1-9. doi: 10.1016/j.jneumeth.2018.06.001. Epub 2018 Jun 4.


APOE-ε4 associates with hippocampal volume, learning, and memory across the spectrum of Alzheimer's disease and dementia with Lewy bodies.

Saeed U, Mirza SS, MacIntosh BJ, Herrmann N, Keith J, Ramirez J, Nestor SM, Yu Q, Knight J, Swardfager W, Potkin SG, Rogaeva E, St George-Hyslop P, Black SE, Masellis M.

Alzheimers Dement. 2018 Sep;14(9):1137-1147. doi: 10.1016/j.jalz.2018.04.005. Epub 2018 May 18.


Aerobic With Resistance Training or Aerobic Training Alone Poststroke: A Secondary Analysis From a Randomized Clinical Trial.

Marzolini S, Brooks D, Oh P, Jagroop D, MacIntosh BJ, Anderson ND, Alter D, Corbett D.

Neurorehabil Neural Repair. 2018 Mar;32(3):209-222. doi: 10.1177/1545968318765692. Epub 2018 Mar 30.


Cerebrovascular blood oxygenation level dependent pulsatility at baseline and following acute exercise among healthy adolescents.

Theyers AE, Goldstein BI, Metcalfe AW, Robertson AD, MacIntosh BJ.

J Cereb Blood Flow Metab. 2018 Mar 21:271678X18766771. doi: 10.1177/0271678X18766771. [Epub ahead of print]


Greater body mass index is associated with reduced frontal cortical volumes among adolescents with bipolar disorder.

Islam AH, Metcalfe AWS, MacIntosh BJ, Korczak DJ, Goldstein BI.

J Psychiatry Neurosci. 2018 Mar;43(2):120-130.


Perivascular Spaces Segmentation in Brain MRI Using Optimal 3D Filtering.

Ballerini L, Lovreglio R, Valdés Hernández MDC, Ramirez J, MacIntosh BJ, Black SE, Wardlaw JM.

Sci Rep. 2018 Feb 1;8(1):2132. doi: 10.1038/s41598-018-19781-5.


Post-stroke Fatigue and Depressive Symptoms Are Differentially Related to Mobility and Cognitive Performance.

MacIntosh BJ, Edwards JD, Kang M, Cogo-Moreira H, Chen JL, Mochizuki G, Herrmann N, Swardfager W.

Front Aging Neurosci. 2017 Oct 31;9:343. doi: 10.3389/fnagi.2017.00343. eCollection 2017.


Greater body mass index is associated with reduced frontal cortical volumes among adolescents with bipolar disorder.

Islam AH, Metcalfe AWS, MacIntosh BJ, Korczak DJ, Goldstein BI.

J Psychiatry Neurosci. 2017 Oct 27;43(1):170041. doi: 10.1503/jpn.170041. [Epub ahead of print]


Exercise Training Increases Parietal Lobe Cerebral Blood Flow in Chronic Stroke: An Observational Study.

Robertson AD, Marzolini S, Middleton LE, Basile VS, Oh PI, MacIntosh BJ.

Front Aging Neurosci. 2017 Sep 29;9:318. doi: 10.3389/fnagi.2017.00318. eCollection 2017.


Enhancement of automated blood flow estimates (ENABLE) from arterial spin-labeled MRI.

Shirzadi Z, Stefanovic B, Chappell MA, Ramirez J, Schwindt G, Masellis M, Black SE, MacIntosh BJ.

J Magn Reson Imaging. 2018 Mar;47(3):647-655. doi: 10.1002/jmri.25807. Epub 2017 Jul 6.


Temporal and Spatial Variances in Arterial Spin-Labeling Are Inversely Related to Large-Artery Blood Velocity.

Robertson AD, Matta G, Basile VS, Black SE, Macgowan CK, Detre JA, MacIntosh BJ.

AJNR Am J Neuroradiol. 2017 Aug;38(8):1555-1561. doi: 10.3174/ajnr.A5257. Epub 2017 Jun 15.


Cerebrovascular reactivity measured by functional magnetic resonance imaging during breath-hold challenge: A systematic review.

Urback AL, MacIntosh BJ, Goldstein BI.

Neurosci Biobehav Rev. 2017 Aug;79:27-47. doi: 10.1016/j.neubiorev.2017.05.003. Epub 2017 May 6. Review.


Comparison of arterial spin labeling registration strategies in the multi-center GENetic frontotemporal dementia initiative (GENFI).

Mutsaerts HJMM, Petr J, Thomas DL, De Vita E, Cash DM, van Osch MJP, Golay X, Groot PFC, Ourselin S, van Swieten J, Laforce R Jr, Tagliavini F, Borroni B, Galimberti D, Rowe JB, Graff C, Pizzini FB, Finger E, Sorbi S, Castelo Branco M, Rohrer JD, Masellis M, MacIntosh BJ; GENFI investigators.

J Magn Reson Imaging. 2018 Jan;47(1):131-140. doi: 10.1002/jmri.25751. Epub 2017 May 8.


The spatial coefficient of variation in arterial spin labeling cerebral blood flow images.

Mutsaerts HJ, Petr J, Václavů L, van Dalen JW, Robertson AD, Caan MW, Masellis M, Nederveen AJ, Richard E, MacIntosh BJ.

J Cereb Blood Flow Metab. 2017 Sep;37(9):3184-3192. doi: 10.1177/0271678X16683690. Epub 2017 Jan 6.


Brain Function Is Linked to LDL Cholesterol in Older Adults with Cardiovascular Risk.

Meusel LC, Anderson ND, Parrott MD, Yuen W, Tchistiakova E, MacIntosh BJ, Feldman S, Greenwood CE.

J Am Geriatr Soc. 2017 Feb;65(2):e51-e55. doi: 10.1111/jgs.14663. Epub 2016 Nov 21.


Increased cerebral blood flow among adolescents with bipolar disorder at rest is reduced following acute aerobic exercise.

MacIntosh BJ, Shirzadi Z, Scavone A, Metcalfe AW, Islam AH, Korczak D, Goldstein BI.

J Affect Disord. 2017 Jan 15;208:205-213. doi: 10.1016/j.jad.2016.08.060. Epub 2016 Oct 21.


Mapping Long-Term Functional Changes in Cerebral Blood Flow by Arterial Spin Labeling.

Ssali T, Anazodo UC, Bureau Y, MacIntosh BJ, Günther M, St Lawrence K.

PLoS One. 2016 Oct 5;11(10):e0164112. doi: 10.1371/journal.pone.0164112. eCollection 2016.


'Under pressure': is there a link between orthostatic hypotension and cognitive impairment in α-synucleinopathies?

Udow SJ, Robertson AD, MacIntosh BJ, Espay AJ, Rowe JB, Lang AE, Masellis M.

J Neurol Neurosurg Psychiatry. 2016 Dec;87(12):1311-1321. doi: 10.1136/jnnp-2016-314123. Epub 2016 Sep 9. Review.


Summative effects of vascular risk factors on cortical thickness in mild cognitive impairment.

Tchistiakova E, MacIntosh BJ; Alzheimer's Disease Neuroimaging Initiative.

Neurobiol Aging. 2016 Sep;45:98-106. doi: 10.1016/j.neurobiolaging.2016.05.011. Epub 2016 May 20.


Depression, Type 2 Diabetes, and Poststroke Cognitive Impairment.

Swardfager W, MacIntosh BJ.

Neurorehabil Neural Repair. 2017 Jan;31(1):48-55. Epub 2016 Jun 29.


Prescribing Aerobic Exercise Intensity without a Cardiopulmonary Exercise Test Post Stroke: Utility of the Six-Minute Walk Test.

Marzolini S, Oh P, Corbett D, Dooks D, Calouro M, MacIntosh BJ, Goodman R, Brooks D.

J Stroke Cerebrovasc Dis. 2016 Sep;25(9):2222-31. doi: 10.1016/j.jstrokecerebrovasdis.2016.04.016. Epub 2016 Jun 8.


Effects of acute aerobic exercise on neural correlates of attention and inhibition in adolescents with bipolar disorder.

Metcalfe AW, MacIntosh BJ, Scavone A, Ou X, Korczak D, Goldstein BI.

Transl Psychiatry. 2016 May 17;6:e814. doi: 10.1038/tp.2016.85.


Regional reduction in cortical blood flow among cognitively impaired adults with relapsing-remitting multiple sclerosis patients.

Hojjat SP, Cantrell CG, Vitorino R, Feinstein A, Shirzadi Z, MacIntosh BJ, Crane DE, Zhang L, Morrow SA, Lee L, O'Connor P, Carroll TJ, Aviv RI.

Mult Scler. 2016 Oct;22(11):1421-1428. Epub 2016 Jan 11.


Orthostatic hypotension, cerebral hypoperfusion, and visuospatial deficits in Lewy body disorders.

Robertson AD, Messner MA, Shirzadi Z, Kleiner-Fisman G, Lee J, Hopyan J, Lang AE, Black SE, MacIntosh BJ, Masellis M.

Parkinsonism Relat Disord. 2016 Jan;22:80-6. doi: 10.1016/j.parkreldis.2015.11.019. Epub 2015 Nov 23.


Characterizing exercise-induced feelings after one bout of exercise among adolescents with and without bipolar disorder.

Subramaniapillai M, Goldstein BI, MacIntosh BJ, Korczak DJ, Ou X, Scavone A, Arbour-Nicitopoulos K, Faulkner G.

J Affect Disord. 2016 Jan 15;190:467-473. doi: 10.1016/j.jad.2015.10.018. Epub 2015 Oct 28.


Physiological fluctuations in white matter are increased in Alzheimer's disease and correlate with neuroimaging and cognitive biomarkers.

Makedonov I, Chen JJ, Masellis M, MacIntosh BJ; Alzheimer's Disease Neuroimaging Initiative.

Neurobiol Aging. 2016 Jan;37:12-18. doi: 10.1016/j.neurobiolaging.2015.09.010. Epub 2015 Sep 21.


Gray matter blood flow and volume are reduced in association with white matter hyperintensity lesion burden: a cross-sectional MRI study.

Crane DE, Black SE, Ganda A, Mikulis DJ, Nestor SM, Donahue MJ, MacIntosh BJ.

Front Aging Neurosci. 2015 Jul 8;7:131. doi: 10.3389/fnagi.2015.00131. eCollection 2015.


Exercise intensity modulates the change in cerebral blood flow following aerobic exercise in chronic stroke.

Robertson AD, Crane DE, Rajab AS, Swardfager W, Marzolini S, Shirzadi Z, Middleton LE, MacIntosh BJ.

Exp Brain Res. 2015 Aug;233(8):2467-75. doi: 10.1007/s00221-015-4317-6. Epub 2015 May 24.


CACNA1C rs1006737 genotype and bipolar disorder: Focus on intermediate phenotypes and cardiovascular comorbidity.

Ou X, Crane DE, MacIntosh BJ, Young LT, Arnold P, Ameis S, Goldstein BI.

Neurosci Biobehav Rev. 2015 Aug;55:198-210. doi: 10.1016/j.neubiorev.2015.04.022. Epub 2015 May 11. Review.


Vascular risk factor burden correlates with cerebrovascular reactivity but not resting state coactivation in the default mode network.

Tchistiakova E, Crane DE, Mikulis DJ, Anderson ND, Greenwood CE, Black SE, MacIntosh BJ.

J Magn Reson Imaging. 2015 Nov;42(5):1369-76. doi: 10.1002/jmri.24917. Epub 2015 Apr 17.


Automated removal of spurious intermediate cerebral blood flow volumes improves image quality among older patients: A clinical arterial spin labeling investigation.

Shirzadi Z, Crane DE, Robertson AD, Maralani PJ, Aviv RI, Chappell MA, Goldstein BI, Black SE, MacIntosh BJ.

J Magn Reson Imaging. 2015 Nov;42(5):1377-85. doi: 10.1002/jmri.24918. Epub 2015 Apr 15.


Estimating the sample size required to detect an arterial spin labelling magnetic resonance imaging perfusion abnormality in voxel-wise group analyses.

Mersov AM, Crane DE, Chappell MA, Black SE, MacIntosh BJ.

J Neurosci Methods. 2015 Apr 30;245:169-77. doi: 10.1016/j.jneumeth.2015.02.017. Epub 2015 Mar 6.


Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis.

Rohrer JD, Nicholas JM, Cash DM, van Swieten J, Dopper E, Jiskoot L, van Minkelen R, Rombouts SA, Cardoso MJ, Clegg S, Espak M, Mead S, Thomas DL, De Vita E, Masellis M, Black SE, Freedman M, Keren R, MacIntosh BJ, Rogaeva E, Tang-Wai D, Tartaglia MC, Laforce R Jr, Tagliavini F, Tiraboschi P, Redaelli V, Prioni S, Grisoli M, Borroni B, Padovani A, Galimberti D, Scarpini E, Arighi A, Fumagalli G, Rowe JB, Coyle-Gilchrist I, Graff C, Fallström M, Jelic V, Ståhlbom AK, Andersson C, Thonberg H, Lilius L, Frisoni GB, Pievani M, Bocchetta M, Benussi L, Ghidoni R, Finger E, Sorbi S, Nacmias B, Lombardi G, Polito C, Warren JD, Ourselin S, Fox NC, Rossor MN, Binetti G.

Lancet Neurol. 2015 Mar;14(3):253-62. doi: 10.1016/S1474-4422(14)70324-2. Epub 2015 Feb 4. Erratum in: Lancet Neurol. 2015 Dec;14(12):1151. Binetti, Giuliano [added].


Differentiating between visual hallucination-free dementia with Lewy bodies and corticobasal syndrome on the basis of neuropsychology and perfusion single-photon emission computed tomography.

Misch MR, Mitchell S, Francis PL, Sherborn K, Meradje K, McNeely AA, Honjo K, Zhao J, Scott CJ, Caldwell CB, Ehrlich L, Shammi P, MacIntosh BJ, Bilbao JM, Lang AE, Black SE, Masellis M.

Alzheimers Res Ther. 2014 Dec 5;6(9):71. doi: 10.1186/s13195-014-0071-4. eCollection 2014.


A single session of exercise increases connectivity in sensorimotor-related brain networks: a resting-state fMRI study in young healthy adults.

Rajab AS, Crane DE, Middleton LE, Robertson AD, Hampson M, MacIntosh BJ.

Front Hum Neurosci. 2014 Aug 14;8:625. doi: 10.3389/fnhum.2014.00625. eCollection 2014.


Regional cerebral arterial transit time hemodynamics correlate with vascular risk factors and cognitive function in men with coronary artery disease.

MacIntosh BJ, Swardfager W, Robertson AD, Tchistiakova E, Saleem M, Oh PI, Herrmann N, Stefanovic B, Lanctôt KL.

AJNR Am J Neuroradiol. 2015 Feb;36(2):295-301. doi: 10.3174/ajnr.A4094. Epub 2014 Aug 21.


A systematic review of type 2 diabetes mellitus and hypertension in imaging studies of cognitive aging: time to establish new norms.

Meusel LA, Kansal N, Tchistiakova E, Yuen W, MacIntosh BJ, Greenwood CE, Anderson ND.

Front Aging Neurosci. 2014 Jul 8;6:148. doi: 10.3389/fnagi.2014.00148. eCollection 2014. Review.


Combined effects of type 2 diabetes and hypertension associated with cortical thinning and impaired cerebrovascular reactivity relative to hypertension alone in older adults.

Tchistiakova E, Anderson ND, Greenwood CE, MacIntosh BJ.

Neuroimage Clin. 2014 Jun 5;5:36-41. doi: 10.1016/j.nicl.2014.05.020. eCollection 2014.


Effects of cannabis on cognition in patients with MS: a psychometric and MRI study.

Pavisian B, MacIntosh BJ, Szilagyi G, Staines RW, O'Connor P, Feinstein A.

Neurology. 2014 May 27;82(21):1879-87. doi: 10.1212/WNL.0000000000000446. Epub 2014 Apr 30.


Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia.

Alsop DC, Detre JA, Golay X, Günther M, Hendrikse J, Hernandez-Garcia L, Lu H, MacIntosh BJ, Parkes LM, Smits M, van Osch MJ, Wang DJ, Wong EC, Zaharchuk G.

Magn Reson Med. 2015 Jan;73(1):102-16. doi: 10.1002/mrm.25197. Epub 2014 Apr 8. Review.


Cardiopulmonary fitness correlates with regional cerebral grey matter perfusion and density in men with coronary artery disease.

MacIntosh BJ, Swardfager W, Crane DE, Ranepura N, Saleem M, Oh PI, Stefanovic B, Herrmann N, Lanctôt KL.

PLoS One. 2014 Mar 12;9(3):e91251. doi: 10.1371/journal.pone.0091251. eCollection 2014.


Modeling and correction of bolus dispersion effects in dynamic susceptibility contrast MRI.

Mehndiratta A, Calamante F, MacIntosh BJ, Crane DE, Payne SJ, Chappell MA.

Magn Reson Med. 2014 Dec;72(6):1762-74. doi: 10.1002/mrm.25077. Epub 2014 Jan 22.


Modeling the residue function in DSC-MRI simulations: analytical approximation to in vivo data.

Mehndiratta A, Calamante F, MacIntosh BJ, Crane DE, Payne SJ, Chappell MA.

Magn Reson Med. 2014 Nov;72(5):1486-91. doi: 10.1002/mrm.25056. Epub 2013 Dec 23.


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