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Items: 1 to 50 of 57

1.

Mitochondrial DNA is critical for longevity and metabolism of transmission stage Trypanosoma brucei.

Dewar CE, MacGregor P, Cooper S, Gould MK, Matthews KR, Savill NJ, Schnaufer A.

PLoS Pathog. 2018 Jul 18;14(7):e1007195. doi: 10.1371/journal.ppat.1007195. eCollection 2018 Jul.

2.

Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes.

McDonald L, Cayla M, Ivens A, Mony BM, MacGregor P, Silvester E, McWilliam K, Matthews KR.

PLoS Pathog. 2018 Jun 25;14(6):e1007145. doi: 10.1371/journal.ppat.1007145. eCollection 2018 Jun.

3.

A Receptor's Tale: An Eon in the Life of a Trypanosome Receptor.

Higgins MK, Lane-Serff H, MacGregor P, Carrington M.

PLoS Pathog. 2017 Jan 26;13(1):e1006055. doi: 10.1371/journal.ppat.1006055. eCollection 2017 Jan. Review.

4.

Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor.

Lane-Serff H, MacGregor P, Peacock L, Macleod OJ, Kay C, Gibson W, Higgins MK, Carrington M.

Elife. 2016 Apr 15;5. pii: e13044. doi: 10.7554/eLife.13044.

5.

How Does the VSG Coat of Bloodstream Form African Trypanosomes Interact with External Proteins?

Schwede A, Macleod OJ, MacGregor P, Carrington M.

PLoS Pathog. 2015 Dec 31;11(12):e1005259. doi: 10.1371/journal.ppat.1005259. eCollection 2015 Dec. Review.

6.

Pharmacists for Patient Safety.

Macgregor P.

Can J Hosp Pharm. 2015 May-Jun;68(3):270. No abstract available.

7.

Pharmaciens œuvrant à la sécurité des patients.

Macgregor P.

Can J Hosp Pharm. 2015 May-Jun;68(3):269. No abstract available.

8.

Change: the future of pharmacy.

Macgregor P.

Can J Hosp Pharm. 2014 Nov;67(6):463-4. English, French. No abstract available.

9.

Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor.

Lane-Serff H, MacGregor P, Lowe ED, Carrington M, Higgins MK.

Elife. 2014 Dec 12;3:e05553. doi: 10.7554/eLife.05553.

10.

A vision of pharmacy practice excellence.

Macgregor P.

Can J Hosp Pharm. 2014 Mar;67(2):176. English, French. No abstract available.

11.

Understanding the conformational impact of chemical modifications on monoclonal antibodies with diverse sequence variation using hydrogen/deuterium exchange mass spectrometry and structural modeling.

Zhang A, Hu P, MacGregor P, Xue Y, Fan H, Suchecki P, Olszewski L, Liu A.

Anal Chem. 2014 Apr 1;86(7):3468-75. doi: 10.1021/ac404130a. Epub 2014 Mar 14.

PMID:
24597564
12.

High-throughput chemical screening for antivirulence developmental phenotypes in Trypanosoma brucei.

MacGregor P, Ivens A, Shave S, Collie I, Gray D, Auer M, Matthews KR.

Eukaryot Cell. 2014 Mar;13(3):412-26. doi: 10.1128/EC.00335-13. Epub 2014 Jan 17.

13.

Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei.

Mony BM, MacGregor P, Ivens A, Rojas F, Cowton A, Young J, Horn D, Matthews K.

Nature. 2014 Jan 30;505(7485):681-685. doi: 10.1038/nature12864. Epub 2013 Dec 15.

14.

Bloodstream form pre-adaptation to the tsetse fly in Trypanosoma brucei.

Rico E, Rojas F, Mony BM, Szoor B, Macgregor P, Matthews KR.

Front Cell Infect Microbiol. 2013 Nov 14;3:78. doi: 10.3389/fcimb.2013.00078. eCollection 2013. Review.

15.

How is CSHP Supporting Hospital Pharmacists?

Macgregor P.

Can J Hosp Pharm. 2013 Sep;66(5):336. No abstract available.

16.

Quel soutien la SCPH apporte-t-elle aux pharmaciens d'hopitaux?

Macgregor P.

Can J Hosp Pharm. 2013 Sep;66(5):335. French. No abstract available.

17.

Regulation of Trypanosoma brucei Total and Polysomal mRNA during Development within Its Mammalian Host.

Capewell P, Monk S, Ivens A, Macgregor P, Fenn K, Walrad P, Bringaud F, Smith TK, Matthews KR.

PLoS One. 2013 Jun 26;8(6):e67069. doi: 10.1371/journal.pone.0067069. Print 2013.

18.

Stable transformation of pleomorphic bloodstream form Trypanosoma brucei.

MacGregor P, Rojas F, Dean S, Matthews KR.

Mol Biochem Parasitol. 2013 Aug;190(2):60-2. doi: 10.1016/j.molbiopara.2013.06.007. Epub 2013 Jul 5.

19.

Achieving the CSHP's Vision for Hospital Pharmacy in Canada.

Macgregor P.

Can J Hosp Pharm. 2013 Jan;66(1):75-6. English, French. No abstract available.

20.

Identification of the regulatory elements controlling the transmission stage-specific gene expression of PAD1 in Trypanosoma brucei.

MacGregor P, Matthews KR.

Nucleic Acids Res. 2012 Sep;40(16):7705-17. doi: 10.1093/nar/gks533. Epub 2012 Jun 7.

21.

Trypanosomal immune evasion, chronicity and transmission: an elegant balancing act.

MacGregor P, Szöőr B, Savill NJ, Matthews KR.

Nat Rev Microbiol. 2012 Apr 30;10(6):431-8. doi: 10.1038/nrmicro2779. Review.

22.

Targeting cattle-borne zoonoses and cattle pathogens using a novel trypanosomatid-based delivery system.

Mott GA, Wilson R, Fernando A, Robinson A, MacGregor P, Kennedy D, Schaap D, Matthews JB, Matthews KR.

PLoS Pathog. 2011 Oct;7(10):e1002340. doi: 10.1371/journal.ppat.1002340. Epub 2011 Oct 27.

23.

Transmission stages dominate trypanosome within-host dynamics during chronic infections.

MacGregor P, Savill NJ, Hall D, Matthews KR.

Cell Host Microbe. 2011 Apr 21;9(4):310-8. doi: 10.1016/j.chom.2011.03.013.

24.

Malaria and trypanosome transmission: different parasites, same rules?

Pollitt LC, MacGregor P, Matthews K, Reece SE.

Trends Parasitol. 2011 May;27(5):197-203. doi: 10.1016/j.pt.2011.01.004. Epub 2011 Feb 21.

25.

New discoveries in the transmission biology of sleeping sickness parasites: applying the basics.

MacGregor P, Matthews KR.

J Mol Med (Berl). 2010 Sep;88(9):865-71. doi: 10.1007/s00109-010-0637-y. Epub 2010 Jun 5. Review.

26.

Modelling trypanosome chronicity: VSG dynasties and parasite density.

MacGregor P, Matthews KR.

Trends Parasitol. 2008 Jan;24(1):1-4. Epub 2007 Nov 19.

27.

Microarray expression identification of differentially expressed genes in serous epithelial ovarian cancer compared with bulk normal ovarian tissue and ovarian surface scrapings.

Grisaru D, Hauspy J, Prasad M, Albert M, Murphy KJ, Covens A, Macgregor PF, Rosen B.

Oncol Rep. 2007 Dec;18(6):1347-56.

PMID:
17982616
28.

On-line H/D exchange LC-MS strategy for structural elucidation of pharmaceutical impurities.

Liu DQ, Wu L, Sun M, MacGregor PA.

J Pharm Biomed Anal. 2007 Jun 28;44(2):320-9. Epub 2007 Jan 19. Review.

PMID:
17317074
29.

High-resolution mapping of genomic imbalance and identification of gene expression profiles associated with differential chemotherapy response in serous epithelial ovarian cancer.

Bernardini M, Lee CH, Beheshti B, Prasad M, Albert M, Marrano P, Begley H, Shaw P, Covens A, Murphy J, Rosen B, Minkin S, Squire JA, Macgregor PF.

Neoplasia. 2005 Jun;7(6):603-13.

30.

Karyotypic imbalances and differential gene expressions in the acquired doxorubicin resistance of hepatocellular carcinoma cells.

Pang E, Hu Y, Chan KY, Lai PB, Squire JA, Macgregor PF, Beheshti B, Albert M, Leung TW, Wong N.

Lab Invest. 2005 May;85(5):664-74.

31.

Transcriptional profiling identifies gene expression changes associated with IFN-alpha tolerance in hepatitis C-related hepatocellular carcinoma cells.

Wong N, Chan KY, Macgregor PF, Lai PB, Squire JA, Beheshti B, Albert M, Leung TW.

Clin Cancer Res. 2005 Feb 1;11(3):1319-26.

32.

Transcriptional profiling on chromosome 19p indicated frequent downregulation of ACP5 expression in hepatocellular carcinoma.

Chan KY, Wong N, Lai PB, Squire JA, Macgregor PF, Beheshti B, Albert M, To KF, Johnson PJ.

Int J Cancer. 2005 May 10;114(6):902-8.

33.

Genetic alterations in doxorubicin-resistant hepatocellular carcinoma cells: a combined study of spectral karyotyping, positional expression profiling and candidate genes.

Hu Y, Pang E, Lai PB, Squire JA, MacGregor PF, Beheshti B, Albert M, Leung TW, Wong N.

Int J Oncol. 2004 Nov;25(5):1357-64.

PMID:
15492826
34.

Distinct gene signatures of transient and acute megakaryoblastic leukemia in Down syndrome.

Lightfoot J, Hitzler JK, Zipursky A, Albert M, Macgregor PF.

Leukemia. 2004 Oct;18(10):1617-23.

PMID:
15343346
35.

Using microarrays to predict resistance to chemotherapy in cancer patients.

Lee CH, Macgregor PF.

Pharmacogenomics. 2004 Sep;5(6):611-25. Review.

PMID:
15335284
36.

5- and 6-glycosylation of transferrin in patients with Alzheimer's disease.

van Rensburg SJ, Berman P, Potocnik F, MacGregor P, Hon D, de Villiers N.

Metab Brain Dis. 2004 Jun;19(1-2):89-96.

PMID:
15214509
37.

Altered expression of genes involved in hepatic morphogenesis and fibrogenesis are identified by cDNA microarray analysis in biliary atresia.

Chen L, Goryachev A, Sun J, Kim P, Zhang H, Phillips MJ, Macgregor P, Lebel S, Edwards AM, Cao Q, Furuya KN.

Hepatology. 2003 Sep;38(3):567-76.

PMID:
12939583
38.

Gene expression in cancer: the application of microarrays.

Macgregor PF.

Expert Rev Mol Diagn. 2003 Mar;3(2):185-200. Review.

PMID:
12647995
39.

Application of microarrays to the analysis of gene expression in cancer.

Macgregor PF, Squire JA.

Clin Chem. 2002 Aug;48(8):1170-7. Review.

40.

Parallel analysis of sporadic primary ovarian carcinomas by spectral karyotyping, comparative genomic hybridization, and expression microarrays.

Bayani J, Brenton JD, Macgregor PF, Beheshti B, Albert M, Nallainathan D, Karaskova J, Rosen B, Murphy J, Laframboise S, Zanke B, Squire JA.

Cancer Res. 2002 Jun 15;62(12):3466-76.

41.

Unfolding of microarray data.

Goryachev AB, Macgregor PF, Edwards AM.

J Comput Biol. 2001;8(4):443-61.

PMID:
11571077
42.

Herpes simplex virus triggers and then disarms a host antiviral response.

Mossman KL, Macgregor PF, Rozmus JJ, Goryachev AB, Edwards AM, Smiley JR.

J Virol. 2001 Jan;75(2):750-8.

43.

RNA polymerase II subunit Rpb9 regulates transcription elongation in vivo.

Hemming SA, Jansma DB, Macgregor PF, Goryachev A, Friesen JD, Edwards AM.

J Biol Chem. 2000 Nov 10;275(45):35506-11.

44.

Grief: the unrecognized parental response to mental illness in a child.

MacGregor P.

Soc Work. 1994 Mar;39(2):160-6. Review.

PMID:
8153758
45.
46.

Direct cloning of leucine zipper proteins: Jun binds cooperatively to the CRE with CRE-BP1.

Macgregor PF, Abate C, Curran T.

Oncogene. 1990 Apr;5(4):451-8.

PMID:
2139203
47.

Inducible proto-oncogene transcription factors: third messengers in the brain?

Curran T, Abate C, Cohen DR, Macgregor PF, Rauscher FJ 3rd, Sonnenberg JL, Connor JA, Morgan JI.

Cold Spring Harb Symp Quant Biol. 1990;55:225-34. Review. No abstract available.

PMID:
2132816
48.

Cutaneous ureterostomy as palliative diversion in adults with malignancy.

MacGregor PS, Montie JE, Straffon RA.

Urology. 1987 Jul;30(1):31-4.

PMID:
2440171
49.

Continent ileal urinary reservoir (Kock pouch).

Montie JE, MacGregor PS, Fazio VW, Lavery I.

Urol Clin North Am. 1986 May;13(2):251-60.

PMID:
3962027
50.

Renal transplantation in end stage renal disease patients with existing urinary diversion.

MacGregor P, Novick AC, Cunningham R, Streem S, Kay R, Steinmuller D, Buszta C, Steinhilber D.

J Urol. 1986 Apr;135(4):686-8.

PMID:
3514957

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