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Items: 1 to 50 of 52

1.

Delineating the role of MITF isoforms in pigmentation and tissue homeostasis.

Flesher JL, Paterson-Coleman EK, Vasudeva P, Ruiz-Vega R, Marshall M, Pearlman E, MacGregor GR, Neumann J, Ganesan AK.

Pigment Cell Melanoma Res. 2020 Mar;33(2):279-292. doi: 10.1111/pcmr.12828. Epub 2019 Oct 16.

PMID:
31562697
2.

Miles to go (mtgo) encodes FNDC3 proteins that interact with the chaperonin subunit CCT3 and are required for NMJ branching and growth in Drosophila.

Syed A, Lukacsovich T, Pomeroy M, Bardwell AJ, Decker GT, Waymire KG, Purcell J, Huang W, Gui J, Padilla EM, Park C, Paul A, Pham TBT, Rodriguez Y, Wei S, Worthge S, Zebarjedi R, Zhang B, Bardwell L, Marsh JL, MacGregor GR.

Dev Biol. 2019 Jan 1;445(1):37-53. doi: 10.1016/j.ydbio.2018.10.016. Epub 2018 Oct 25.

3.

Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain.

Fonseca MI, Chu SH, Hernandez MX, Fang MJ, Modarresi L, Selvan P, MacGregor GR, Tenner AJ.

J Neuroinflammation. 2017 Mar 6;14(1):48. doi: 10.1186/s12974-017-0814-9.

4.

Deficiency in the mouse mitochondrial adenine nucleotide translocator isoform 2 gene is associated with cardiac noncompaction.

Kokoszka JE, Waymire KG, Flierl A, Sweeney KM, Angelin A, MacGregor GR, Wallace DC.

Biochim Biophys Acta. 2016 Aug;1857(8):1203-1212. doi: 10.1016/j.bbabio.2016.03.026. Epub 2016 Apr 24.

5.

Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle.

Paterson EK, Fielder TJ, MacGregor GR, Ito S, Wakamatsu K, Gillen DL, Eby V, Boissy RE, Ganesan AK.

PLoS One. 2015 Nov 30;10(11):e0143702. doi: 10.1371/journal.pone.0143702. eCollection 2015.

6.

Gene loss in keratinization programs accompanies adaptation of cetacean skin to aquatic lifestyle.

Oh JW, Chung O, Cho YS, MacGregor GR, Plikus MV.

Exp Dermatol. 2015 Aug;24(8):572-3. doi: 10.1111/exd.12756. No abstract available.

7.

BMP signaling is required for cell cleavage in preimplantation-mouse embryos.

Reyes de Mochel NS, Luong M, Chiang M, Javier AL, Luu E, Toshihiko F, MacGregor GR, Cinquin O, Cho KW.

Dev Biol. 2015 Jan 1;397(1):45-55. doi: 10.1016/j.ydbio.2014.10.001. Epub 2014 Oct 14.

8.

Mouse mtDNA mutant model of Leber hereditary optic neuropathy.

Lin CS, Sharpley MS, Fan W, Waymire KG, Sadun AA, Carelli V, Ross-Cisneros FN, Baciu P, Sung E, McManus MJ, Pan BX, Gil DW, Macgregor GR, Wallace DC.

Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):20065-70. doi: 10.1073/pnas.1217113109. Epub 2012 Nov 5.

9.

Comparison of male chimeric mice generated from microinjection of JM8.N4 embryonic stem cells into C57BL/6J and C57BL/6NTac blastocysts.

Fielder TJ, Yi CS, Masumi J, Waymire KG, Chen HW, Wang S, Shi KX, Wallace DC, MacGregor GR.

Transgenic Res. 2012 Dec;21(6):1149-58. doi: 10.1007/s11248-012-9605-3. Epub 2012 Mar 16.

10.

The C57BL/6J Mouse Strain Background Modifies the Effect of a Mutation in Bcl2l2.

Navarro SJ, Trinh T, Lucas CA, Ross AJ, Waymire KG, Macgregor GR.

G3 (Bethesda). 2012 Jan;2(1):99-102. doi: 10.1534/g3.111.000778. Epub 2012 Jan 1.

11.

Age-Dependent Resistance to Excitotoxicity in Htt CAG140 Mice and the Effect of Strain Background.

Strong MK, Southwell AL, Yonan JM, Hayden MR, Macgregor GR, Thompson LM, Steward O.

J Huntingtons Dis. 2012;1(2):221-41. doi: 10.3233/JHD-129005.

12.

Diet-induced obesity in two C57BL/6 substrains with intact or mutant nicotinamide nucleotide transhydrogenase (Nnt) gene.

Nicholson A, Reifsnyder PC, Malcolm RD, Lucas CA, MacGregor GR, Zhang W, Leiter EH.

Obesity (Silver Spring). 2010 Oct;18(10):1902-5. doi: 10.1038/oby.2009.477. Epub 2010 Jan 7.

13.

TTLL10 is a protein polyglycylase that can modify nucleosome assembly protein 1.

Ikegami K, Horigome D, Mukai M, Livnat I, MacGregor GR, Setou M.

FEBS Lett. 2008 Apr 2;582(7):1129-34. doi: 10.1016/j.febslet.2008.02.079. Epub 2008 Mar 10.

14.

A mouse model of mitochondrial disease reveals germline selection against severe mtDNA mutations.

Fan W, Waymire KG, Narula N, Li P, Rocher C, Coskun PE, Vannan MA, Narula J, Macgregor GR, Wallace DC.

Science. 2008 Feb 15;319(5865):958-62. doi: 10.1126/science.1147786.

15.

SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release.

Yao I, Takagi H, Ageta H, Kahyo T, Sato S, Hatanaka K, Fukuda Y, Chiba T, Morone N, Yuasa S, Inokuchi K, Ohtsuka T, Macgregor GR, Tanaka K, Setou M.

Cell. 2007 Sep 7;130(5):943-57. Erratum in: Cell. 2007 Oct 5;131(1):190.

16.

Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function.

Ikegami K, Heier RL, Taruishi M, Takagi H, Mukai M, Shimma S, Taira S, Hatanaka K, Morone N, Yao I, Campbell PK, Yuasa S, Janke C, Macgregor GR, Setou M.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3213-8. Epub 2007 Feb 20.

17.

FNDC3A is required for adhesion between spermatids and Sertoli cells.

Obholz KL, Akopyan A, Waymire KG, MacGregor GR.

Dev Biol. 2006 Oct 15;298(2):498-513. Epub 2006 Jul 8.

18.

TTLL7 is a mammalian beta-tubulin polyglutamylase required for growth of MAP2-positive neurites.

Ikegami K, Mukai M, Tsuchida J, Heier RL, Macgregor GR, Setou M.

J Biol Chem. 2006 Oct 13;281(41):30707-16. Epub 2006 Aug 9.

19.

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore.

Kokoszka JE, Waymire KG, Levy SE, Sligh JE, Cai J, Jones DP, MacGregor GR, Wallace DC.

Nature. 2004 Jan 29;427(6973):461-5.

20.

Mutation of a novel gene results in abnormal development of spermatid flagella, loss of intermale aggression and reduced body fat in mice.

Campbell PK, Waymire KG, Heier RL, Sharer C, Day DE, Reimann H, Jaje JM, Friedrich GA, Burmeister M, Bartness TJ, Russell LD, Young LJ, Zimmer M, Jenne DE, MacGregor GR.

Genetics. 2002 Sep;162(1):307-20.

21.
22.

BCLW mediates survival of postmitotic Sertoli cells by regulating BAX activity.

Ross AJ, Amy SP, Mahar PL, Lindsten T, Knudson CM, Thompson CB, Korsmeyer SJ, MacGregor GR.

Dev Biol. 2001 Nov 15;239(2):295-308.

23.

Spermatogenesis in Bclw-deficient mice.

Russell LD, Warren J, Debeljuk L, Richardson LL, Mahar PL, Waymire KG, Amy SP, Ross AJ, MacGregor GR.

Biol Reprod. 2001 Jul;65(1):318-32.

24.

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak.

Zong WX, Lindsten T, Ross AJ, MacGregor GR, Thompson CB.

Genes Dev. 2001 Jun 15;15(12):1481-6.

25.

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death.

Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB, Korsmeyer SJ.

Science. 2001 Apr 27;292(5517):727-30.

26.

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.

Lindsten T, Ross AJ, King A, Zong WX, Rathmell JC, Shiels HA, Ulrich E, Waymire KG, Mahar P, Frauwirth K, Chen Y, Wei M, Eng VM, Adelman DM, Simon MC, Ma A, Golden JA, Evan G, Korsmeyer SJ, MacGregor GR, Thompson CB.

Mol Cell. 2000 Dec;6(6):1389-99.

27.

Maternal germ-line transmission of mutant mtDNAs from embryonic stem cell-derived chimeric mice.

Sligh JE, Levy SE, Waymire KG, Allard P, Dillehay DL, Nusinowitz S, Heckenlively JR, MacGregor GR, Wallace DC.

Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14461-6.

28.

Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene.

Esposito LA, Kokoszka JE, Waymire KG, Cottrell B, MacGregor GR, Wallace DC.

Free Radic Biol Med. 2000 Mar 1;28(5):754-66.

29.

Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia.

Fedde KN, Blair L, Silverstein J, Coburn SP, Ryan LM, Weinstein RS, Waymire K, Narisawa S, Millán JL, MacGregor GR, Whyte MP.

J Bone Miner Res. 1999 Dec;14(12):2015-26.

30.

Transfer of chloramphenicol-resistant mitochondrial DNA into the chimeric mouse.

Levy SE, Waymire KG, Kim YL, MacGregor GR, Wallace DC.

Transgenic Res. 1999 Apr;8(2):137-45.

31.

Increased affiliative response to vasopressin in mice expressing the V1a receptor from a monogamous vole.

Young LJ, Nilsen R, Waymire KG, MacGregor GR, Insel TR.

Nature. 1999 Aug 19;400(6746):766-8.

PMID:
10466725
32.

A systematic molecular genetic approach to study mammalian germline development.

Abe K, Ko MS, MacGregor GR.

Int J Dev Biol. 1998;42(7):1051-65. Review.

33.

Testicular degeneration in Bclw-deficient mice.

Ross AJ, Waymire KG, Moss JE, Parlow AF, Skinner MK, Russell LD, MacGregor GR.

Nat Genet. 1998 Mar;18(3):251-6.

PMID:
9500547
34.

A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator.

Graham BH, Waymire KG, Cottrell B, Trounce IA, MacGregor GR, Wallace DC.

Nat Genet. 1997 Jul;16(3):226-34.

PMID:
9207786
35.

The 5' flanking region of the monogamous prairie vole oxytocin receptor gene directs tissue-specific expression in transgenic mice.

Young LJ, Waymire KG, Nilsen R, Macgregor GR, Wang Z, Insel TR.

Ann N Y Acad Sci. 1997 Jan 15;807:514-7. No abstract available.

PMID:
9071386
36.

Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6.

Waymire KG, Mahuren JD, Jaje JM, Guilarte TR, Coburn SP, MacGregor GR.

Nat Genet. 1995 Sep;11(1):45-51.

PMID:
7550313
38.

Deficiency in fertilization by morphologically abnormal sperm produced by azh mutant mice.

Meistrich ML, Kasai K, Olds-Clarke P, MacGregor GR, Berkowitz AD, Tung KS.

Mol Reprod Dev. 1994 Jan;37(1):69-77.

PMID:
8129933
39.

Targeting of hexokinase 1 to liver and hepatoma mitochondria.

Gelb BD, Adams V, Jones SN, Griffin LD, MacGregor GR, McCabe ER.

Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):202-6.

40.
41.
42.

Testis structure in the sys (symplastic spermatids) mouse.

Russell LD, Hikim AP, Overbeek PA, MacGregor GR.

Am J Anat. 1991 Oct;192(2):169-82.

PMID:
1759682
43.

Use of Escherichiu coli (E. coli) lacZ (β-Galactosidase) as a Reporter Gene.

Macgregor GR, Nolan GP, Fiering S, Roederer M, Herzenberg LA.

Methods Mol Biol. 1991;7:217-35. doi: 10.1385/0-89603-178-0:217.

PMID:
21416358
44.

Symplastic spermatids (sys): a recessive insertional mutation in mice causing a defect in spermatogenesis.

MacGregor GR, Russell LD, Van Beek ME, Hanten GR, Kovac MJ, Kozak CA, Meistrich ML, Overbeek PA.

Proc Natl Acad Sci U S A. 1990 Jul;87(13):5016-20.

45.

Synthesis and characterization of a bovine hexokinase 1 cDNA probe by mixed oligonucleotide primed amplification of cDNA using high complexity primer mixtures.

Griffin LD, MacGregor GR, Muzny DM, Harter J, Cook RG, McCabe ER.

Biochem Med Metab Biol. 1989 Apr;41(2):125-31.

PMID:
2719857
46.

Construction of plasmids that express E. coli beta-galactosidase in mammalian cells.

MacGregor GR, Caskey CT.

Nucleic Acids Res. 1989 Mar 25;17(6):2365. No abstract available.

47.

Expression vectors for human adenosine deaminase gene therapy.

Moore KA, Fletcher FA, Alford RL, Villalon DK, Hawkins DH, MacGregor GR, Caskey CT, Belmont JW.

Genome. 1989;31(2):832-9.

PMID:
2576653
48.

Expression of human adenosine deaminase in murine hematopoietic cells.

Belmont JW, MacGregor GR, Wager-Smith K, Fletcher FA, Moore KA, Hawkins D, Villalon D, Chang SM, Caskey CT.

Mol Cell Biol. 1988 Dec;8(12):5116-25.

49.

Human gene expression in murine hemopoietic cells in vivo.

Fletcher FA, Moore KA, MacGregor GR, Belmont JW, Caskey CT.

Adv Exp Med Biol. 1988;241:123-7. No abstract available.

PMID:
3223402
50.

Analysis of mutations occurring during replication of a SV40 shuttle vector in mammalian cells.

MacGregor GR, James MR, Arlett CF, Burke JF.

Mutat Res. 1987 May;183(3):273-8.

PMID:
3033492

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