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Items: 1 to 50 of 128

1.

Fusion peptides promote formation of bilayer cubic phases in lipid dispersions. An x-ray diffraction study.

Tenchov BG, MacDonald RC, Lentz BR.

Biophys J. 2013 Mar 5;104(5):1029-37. doi: 10.1016/j.bpj.2012.12.034.

2.

End-of-life healthcare decision-making: the intermediary role of the ethicist in supporting family caregivers and health professionals.

MacDonald RC, Weeks LE, McInnis-Perry G.

Work. 2011;40(1):63-73. doi: 10.3233/WOR-2011-1207.

PMID:
21849749
3.

Cationic phospholiposomes: efficient delivery vehicles of anticancer derivatives of ATP to multiple myeloma cells.

Wang L, MacDonald RC.

J Liposome Res. 2011 Dec;21(4):306-14. doi: 10.3109/08982104.2011.565476. Epub 2011 Apr 2.

PMID:
21457078
4.

Encapsulation of NF-kappaB decoy oligonucleotides within echogenic liposomes and ultrasound-triggered release.

Buchanan KD, Huang SL, Kim H, McPherson DD, MacDonald RC.

J Control Release. 2010 Jan 25;141(2):193-8. doi: 10.1016/j.jconrel.2009.09.017. Epub 2009 Oct 3.

5.

Nitric oxide-loaded echogenic liposomes for nitric oxide delivery and inhibition of intimal hyperplasia.

Huang SL, Kee PH, Kim H, Moody MR, Chrzanowski SM, Macdonald RC, McPherson DD.

J Am Coll Cardiol. 2009 Aug 11;54(7):652-9. doi: 10.1016/j.jacc.2009.04.039.

6.

Hydrophobic moiety of cationic lipids strongly modulates their transfection activity.

Koynova R, Tenchov B, Wang L, Macdonald RC.

Mol Pharm. 2009 May-Jun;6(3):951-8. doi: 10.1021/mp8002573.

7.

Modulation of a membrane lipid lamellar-nonlamellar phase transition by cationic lipids: a measure for transfection efficiency.

Tenchov BG, Wang L, Koynova R, MacDonald RC.

Biochim Biophys Acta. 2008 Oct;1778(10):2405-12. doi: 10.1016/j.bbamem.2008.07.022. Epub 2008 Aug 5.

8.

Synthesis, acoustic stability, and pharmacologic activities of papaverine-loaded echogenic liposomes for ultrasound controlled drug delivery.

Kee PH, Abruzzo TA, Smith DA, Kopechek JA, Wang B, Huang SL, MacDonald RC, Holland CK, McPherson DD.

J Liposome Res. 2008;18(4):263-77. doi: 10.1080/08982100802354558 .

9.

Cationic phospholipids forming cubic phases: lipoplex structure and transfection efficiency.

Koynova R, Wang L, Macdonald RC.

Mol Pharm. 2008 Sep-Oct;5(5):739-44. doi: 10.1021/mp800011e. Epub 2008 Jun 19.

PMID:
18563910
10.

A method to co-encapsulate gas and drugs in liposomes for ultrasound-controlled drug delivery.

Huang SL, McPherson DD, Macdonald RC.

Ultrasound Med Biol. 2008 Aug;34(8):1272-80. doi: 10.1016/j.ultrasmedbio.2008.01.005. Epub 2008 Apr 14.

11.
12.

Single lipoplex study of cationic lipoid-DNA, self-assembled complexes.

Pozharski EV, MacDonald RC.

Mol Pharm. 2007 Nov-Dec;4(6):962-74. Epub 2007 Oct 10.

PMID:
17927203
13.

Echogenic liposome compositions for increased retention of ultrasound reflectivity at physiologic temperature.

Buchanan KD, Huang S, Kim H, Macdonald RC, McPherson DD.

J Pharm Sci. 2008 Jun;97(6):2242-9.

14.

Synergy in lipofection by cationic lipid mixtures: superior activity at the gel-liquid crystalline phase transition.

Koynova R, Wang L, MacDonald RC.

J Phys Chem B. 2007 Jul 12;111(27):7786-95. Epub 2007 Jun 16.

16.

Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound.

Smith DA, Porter TM, Martinez J, Huang S, MacDonald RC, McPherson DD, Holland CK.

Ultrasound Med Biol. 2007 May;33(5):797-809. Epub 2007 Apr 6.

PMID:
17412486
17.

Synergistic effect between components of mixtures of cationic amphipaths in transfection of primary endothelial cells.

Wang L, MacDonald RC.

Mol Pharm. 2007 Jul-Aug;4(4):615-23. Epub 2007 Apr 5.

PMID:
17408283
18.

Fibrin targeting of tissue plasminogen activator-loaded echogenic liposomes.

Tiukinhoy-Laing SD, Buchanan K, Parikh D, Huang S, MacDonald RC, McPherson DD, Klegerman ME.

J Drug Target. 2007 Feb;15(2):109-14.

PMID:
17365281
19.

Lipoplex formulation of superior efficacy exhibits high surface activity and fusogenicity, and readily releases DNA.

Koynova R, Tarahovsky YS, Wang L, MacDonald RC.

Biochim Biophys Acta. 2007 Feb;1768(2):375-86. Epub 2006 Nov 1.

20.

Lipid encapsulation of arsenic trioxide attenuates cytotoxicity and allows for controlled anticancer drug release.

Chen H, MacDonald RC, Li S, Krett NL, Rosen ST, O'Halloran TV.

J Am Chem Soc. 2006 Oct 18;128(41):13348-9.

PMID:
17031934
21.

An intracellular lamellar-nonlamellar phase transition rationalizes the superior performance of some cationic lipid transfection agents.

Koynova R, Wang L, MacDonald RC.

Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14373-8. Epub 2006 Sep 18.

23.

Cubic phases in phosphatidylcholine-cholesterol mixtures: cholesterol as membrane "fusogen".

Tenchov BG, MacDonald RC, Siegel DP.

Biophys J. 2006 Oct 1;91(7):2508-16. Epub 2006 Jul 7.

24.
25.

Effect of vinblastine on transfection: influence of cell types, cationic lipids and promoters.

Wang L, Dean DA, Macdonald RC.

Curr Drug Deliv. 2005 Jan;2(1):93-6.

PMID:
16305411
26.

Lipid phase control of DNA delivery.

Koynova R, Wang L, Tarahovsky Y, MacDonald RC.

Bioconjug Chem. 2005 Nov-Dec;16(6):1335-9. Review.

PMID:
16287225
27.

Lipid transfer between cationic vesicles and lipid-DNA lipoplexes: effect of serum.

Koynova R, MacDonald RC.

Biochim Biophys Acta. 2005 Aug 1;1714(1):63-70.

28.

Analysis of the structure and composition of individual lipoplex particles by flow fluorometry.

Pozharski EV, Macdonald RC.

Anal Biochem. 2005 Jun 15;341(2):230-40.

PMID:
15907868
29.

Acoustically active liposomes for drug encapsulation and ultrasound-triggered release.

Huang SL, MacDonald RC.

Biochim Biophys Acta. 2004 Oct 11;1665(1-2):134-41.

30.

Mechanisms of lipoplex formation: dependence of the biological properties of transfection complexes on formulation procedures.

Rakhmanova VA, Pozharski EV, MacDonald RC.

J Membr Biol. 2004 Jul 1;200(1):35-45.

PMID:
15386158
31.
32.

Novel polyamine-dialkyl phosphate conjugates for gene carriers. Facile synthetic route via an unprecedented dialkyl phosphate.

Dewa T, Ieda Y, Morita K, Wang L, MacDonald RC, Iida K, Yamashita K, Oku N, Nango M.

Bioconjug Chem. 2004 Jul-Aug;15(4):824-30.

PMID:
15264870
33.
35.
36.

In vitro characterization of liposomes and Optison by acoustic scattering at 3.5 MHz.

Coussios CC, Holland CK, Jakubowska L, Huang SL, MacDonald RC, Nagaraj A, McPherson DD.

Ultrasound Med Biol. 2004 Feb;30(2):181-90.

37.

Novel echogenic drug-immunoliposomes for drug delivery.

Tiukinhoy SD, Khan AA, Huang S, Klegerman ME, MacDonald RC, McPherson DD.

Invest Radiol. 2004 Feb;39(2):104-10.

PMID:
14734925
38.
39.
40.

Bilayer mixing, fusion, and lysis following the interaction of populations of cationic and anionic phospholipid bilayer vesicles.

Pantazatos DP, Pantazatos SP, MacDonald RC.

J Membr Biol. 2003 Jul 15;194(2):129-39.

PMID:
14502437
41.
42.

Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome.

Lim W, Hearle N, Shah B, Murday V, Hodgson SV, Lucassen A, Eccles D, Talbot I, Neale K, Lim AG, O'Donohue J, Donaldson A, Macdonald RC, Young ID, Robinson MH, Lee PW, Stoodley BJ, Tomlinson I, Alderson D, Holbrook AG, Vyas S, Swarbrick ET, Lewis AA, Phillips RK, Houlston RS.

Br J Cancer. 2003 Jul 21;89(2):308-13.

43.
44.

Real-time observation of lipoplex formation and interaction with anionic bilayer vesicles.

Pantazatos SP, MacDonald RC.

J Membr Biol. 2003 Jan 15;191(2):99-112.

PMID:
12533777
45.

Liposomes as ultrasound imaging contrast agents and as ultrasound-sensitive drug delivery agents.

Huang S, Hamilton AJ, Tiukinhoy SD, Nagaraj A, Kane BJ, Klegerman M, McPherson DD, MacDonald RC.

Cell Mol Biol Lett. 2002;7(2):233-5. No abstract available.

PMID:
12097929
46.
47.

Physical correlates of the ultrasonic reflectivity of lipid dispersions suitable as diagnostic contrast agents.

Huang SL, Hamilton AJ, Pozharski E, Nagaraj A, Klegerman ME, McPherson DD, MacDonald RC.

Ultrasound Med Biol. 2002 Mar;28(3):339-48.

PMID:
11978414
48.

Atomic force microscopy of the erythrocyte membrane skeleton.

Swihart AH, Mikrut JM, Ketterson JB, Macdonald RC.

J Microsc. 2001 Dec;204(Pt 3):212-25.

49.

High temperature stabilization of DNA in complexes with cationic lipids.

Tarahovsky YS, Rakhmanova VA, Epand RM, MacDonald RC.

Biophys J. 2002 Jan;82(1 Pt 1):264-73.

50.

Improving ultrasound reflectivity and stability of echogenic liposomal dispersions for use as targeted ultrasound contrast agents.

Huang SL, Hamilton AJ, Nagaraj A, Tiukinhoy SD, Klegerman ME, McPherson DD, Macdonald RC.

J Pharm Sci. 2001 Dec;90(12):1917-26.

PMID:
11745750

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