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Items: 1 to 50 of 330

1.
2.

Patients' perspectives on integrated oral healthcare in a northern Quebec Indigenous primary health care organisation: a qualitative study.

Shrivastava R, Couturier Y, Kadoch N, Girard F, Bedos C, Macdonald ME, Torrie J, Emami E.

BMJ Open. 2019 Jul 30;9(7):e030005. doi: 10.1136/bmjopen-2019-030005.

3.

Full sequence of mutant huntingtin 3'-untranslated region and modulation of its gene regulatory activity by endogenous microRNA.

Kim KH, Abu Elneel K, Shin JW, Keum JW, Seong D, Kwak S, Lee R, Gusella JF, MacDonald ME, Seong IS, Lee JM.

J Hum Genet. 2019 Oct;64(10):995-1004. doi: 10.1038/s10038-019-0639-8. Epub 2019 Jul 11.

PMID:
31296921
4.

GDF10 blocks hepatic PPARγ activation to protect against diet-induced liver injury.

Platko K, Lebeau PF, Byun JH, Poon SV, Day EA, MacDonald ME, Holzapfel N, Mejia-Benitez A, Maclean KN, Krepinsky JC, Austin RC.

Mol Metab. 2019 Sep;27:62-74. doi: 10.1016/j.molmet.2019.06.021. Epub 2019 Jun 28.

5.

A qualitative study on the oral health of humanitarian migrants in Canada.

Keboa M, Nicolau B, Hovey R, Esfandiari S, Carnevale F, Macdonald ME.

Community Dent Health. 2019 May 30;36(2):95-100. doi: 10.1922/CDH_4455Keboa06.

PMID:
31021567
6.

Diet-induced hepatic steatosis abrogates cell-surface LDLR by inducing de novo PCSK9 expression in mice.

Lebeau PF, Byun JH, Platko K, MacDonald ME, Poon SV, Faiyaz M, Seidah NG, Austin RC.

J Biol Chem. 2019 Jun 7;294(23):9037-9047. doi: 10.1074/jbc.RA119.008094. Epub 2019 Apr 19.

PMID:
31004037
7.

Aortic graft infection with enteric organism after embolization of late type II endoleak.

Li B, Tan KT, MacDonald ME, Byrne J.

J Vasc Surg Cases Innov Tech. 2019 Mar 11;5(1):61-64. doi: 10.1016/j.jvscit.2018.10.009. eCollection 2019 Mar.

8.

Hypomorphic mutation of the mouse Huntington's disease gene orthologue.

Murthy V, Tebaldi T, Yoshida T, Erdin S, Calzonetti T, Vijayvargia R, Tripathi T, Kerschbamer E, Seong IS, Quattrone A, Talkowski ME, Gusella JF, Georgopoulos K, MacDonald ME, Biagioli M.

PLoS Genet. 2019 Mar 21;15(3):e1007765. doi: 10.1371/journal.pgen.1007765. eCollection 2019 Mar.

9.

Oral healthcare experiences of humanitarian migrants in Montreal, Canada.

Keboa MT, Hovey R, Nicolau B, Esfandiari S, Carnevale F, Macdonald ME.

Can J Public Health. 2019 Aug;110(4):453-461. doi: 10.17269/s41997-019-00193-5. Epub 2019 Mar 8.

PMID:
30850954
10.

The Oral Health of Refugees and Asylum Seekers in Canada: A Mixed Methods Study Protocol.

Macdonald ME, Keboa MT, Nurelhuda NM, Lawrence HP, Carnevale F, McNally M, Singhal S, Ka K, Nicolau B.

Int J Environ Res Public Health. 2019 Feb 13;16(4). pii: E542. doi: 10.3390/ijerph16040542.

11.

Bioenergetic deficits in Huntington's disease iPSC-derived neural cells and rescue with glycolytic metabolites.

Kedaigle AJ, Fraenkel E, Atwal RS, Wu M, Gusella JF, MacDonald ME, Kaye JA, Finkbeiner S, Mattis VB, Tom CM, Svendsen C, King AR, Chen Y, Stocksdale JT, Lim RG, Casale M, Wang PH, Thompson LM, Akimov SS, Ratovitski T, Arbez N, Ross CA.

Hum Mol Genet. 2019 Feb 15. pii: ddy430. doi: 10.1093/hmg/ddy430. [Epub ahead of print]

PMID:
30768179
12.

Dentistry and nursing working together to improve oral health care in a long-term care facility.

Keboa M, Beaudin A, Cyr J, Decoste J, Power F, Hovey R, LaFrance L, Ouellet D, Wiseman M, Macdonald ME.

Geriatr Nurs. 2019 Mar - Apr;40(2):197-204. doi: 10.1016/j.gerinurse.2018.10.002. Epub 2018 Oct 24.

PMID:
30528781
13.

Beyond bare bones: critical, theoretically engaged qualitative research in public health.

Mykhalovskiy E, Eakin J, Beagan B, Beausoleil N, Gibson BE, Macdonald ME, Rock MJ.

Can J Public Health. 2018 Dec;109(5-6):613-621. doi: 10.17269/s41997-018-0154-2. Epub 2018 Nov 21.

PMID:
30465286
14.

Of dilemmas and tensions: a qualitative study of palliative care physicians' positions regarding voluntary active euthanasia in Quebec, Canada.

Bélanger E, Towers A, Wright DK, Chen Y, Tradounsky G, Macdonald ME.

J Med Ethics. 2019 Jan;45(1):48-53. doi: 10.1136/medethics-2017-104339. Epub 2018 Oct 30.

PMID:
30377217
15.

Hyperglycemia Aggravates Diet-Induced Coronary Artery Disease and Myocardial Infarction in SR-B1-Knockout/ApoE-Hypomorphic Mice.

Gonzalez L, MacDonald ME, Deng YD, Trigatti BL.

Front Physiol. 2018 Oct 9;9:1398. doi: 10.3389/fphys.2018.01398. eCollection 2018.

16.

Interdatabase Variability in Cortical Thickness Measurements.

MacDonald ME, Williams RJ, Forkert ND, Berman AJL, McCreary CR, Frayne R, Pike GB.

Cereb Cortex. 2018 Aug 23. doi: 10.1093/cercor/bhy197. [Epub ahead of print]

PMID:
30137246
17.

Genetic Modification of Huntington Disease Acts Early in the Prediagnosis Phase.

Long JD, Lee JM, Aylward EH, Gillis T, Mysore JS, Abu Elneel K, Chao MJ, Paulsen JS, MacDonald ME, Gusella JF.

Am J Hum Genet. 2018 Sep 6;103(3):349-357. doi: 10.1016/j.ajhg.2018.07.017. Epub 2018 Aug 16.

18.

Health status, emergency department visits, and oncologists' feedback: An analysis of secondary endpoints from a randomized phase II geriatric assessment trial.

Sattar S, Alibhai SMH, Brennenstuhl S, Kulik M, MacDonald ME, McWatters K, Lee K, Jang R, Amir E, Krzyzanowska MK, Joshua AM, Monette J, Wan-Chow-Wah D, Puts MTE.

J Geriatr Oncol. 2019 Jan;10(1):169-174. doi: 10.1016/j.jgo.2018.06.014. Epub 2018 Jul 21.

PMID:
30041978
19.

Whole head quantitative susceptibility mapping using a least-norm direct dipole inversion method.

Sun H, Ma Y, MacDonald ME, Pike GB.

Neuroimage. 2018 Oct 1;179:166-175. doi: 10.1016/j.neuroimage.2018.06.036. Epub 2018 Jun 15.

PMID:
29906634
20.

Novel DNA Aptamers that Bind to Mutant Huntingtin and Modify Its Activity.

Shin B, Jung R, Oh H, Owens GE, Lee H, Kwak S, Lee R, Cotman SL, Lee JM, MacDonald ME, Song JJ, Vijayvargia R, Seong IS.

Mol Ther Nucleic Acids. 2018 Jun 1;11:416-428. doi: 10.1016/j.omtn.2018.03.008. Epub 2018 Mar 16.

21.

Modeling hyperoxia-induced BOLD signal dynamics to estimate cerebral blood flow, volume and mean transit time.

MacDonald ME, Berman AJL, Mazerolle EL, Williams RJ, Pike GB.

Neuroimage. 2018 Sep;178:461-474. doi: 10.1016/j.neuroimage.2018.05.066. Epub 2018 May 29.

PMID:
29852282
22.

Population-specific genetic modification of Huntington's disease in Venezuela.

Chao MJ, Kim KH, Shin JW, Lucente D, Wheeler VC, Li H, Roach JC, Hood L, Wexler NS, Jardim LB, Holmans P, Jones L, Orth M, Kwak S, MacDonald ME, Gusella JF, Lee JM.

PLoS Genet. 2018 May 11;14(5):e1007274. doi: 10.1371/journal.pgen.1007274. eCollection 2018 May.

23.

Assessing Dental Students' Readiness to Treat Populations That Are Underserved: A Scoping Review.

Furlini L, Noushi N, Castonguay G, Allison P, Bedos C, De Souza R, Esfandiari S, Hovey R, Macdonald ME, Morris M, Nicolau B, Power F, Feine J.

J Dent Educ. 2018 May;82(5):483-491. doi: 10.21815/JDE.018.053. Review.

24.

Transcriptional regulatory networks underlying gene expression changes in Huntington's disease.

Ament SA, Pearl JR, Cantle JP, Bragg RM, Skene PJ, Coffey SR, Bergey DE, Wheeler VC, MacDonald ME, Baliga NS, Rosinski J, Hood LE, Carroll JB, Price ND.

Mol Syst Biol. 2018 Mar 26;14(3):e7435. doi: 10.15252/msb.20167435.

25.

Relational ethics of delirium care: Findings from a hospice ethnography.

Wright DK, Brajtman S, Macdonald ME.

Nurs Inq. 2018 Jul;25(3):e12234. doi: 10.1111/nin.12234. Epub 2018 Mar 24.

PMID:
29573054
26.

HttQ111/+ Huntington's Disease Knock-in Mice Exhibit Brain Region-Specific Morphological Changes and Synaptic Dysfunction.

Kovalenko M, Milnerwood A, Giordano J, St Claire J, Guide JR, Stromberg M, Gillis T, Sapp E, DiFiglia M, MacDonald ME, Carroll JB, Lee JM, Tappan S, Raymond L, Wheeler VC.

J Huntingtons Dis. 2018;7(1):17-33. doi: 10.3233/JHD-170282.

27.

Gas-free calibrated fMRI with a correction for vessel-size sensitivity.

Berman AJL, Mazerolle EL, MacDonald ME, Blockley NP, Luh WM, Pike GB.

Neuroimage. 2018 Apr 1;169:176-188. doi: 10.1016/j.neuroimage.2017.12.047. Epub 2017 Dec 15.

PMID:
29253657
28.

Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases.

Handley RR, Reid SJ, Brauning R, Maclean P, Mears ER, Fourie I, Patassini S, Cooper GJS, Rudiger SR, McLaughlan CJ, Verma PJ, Gusella JF, MacDonald ME, Waldvogel HJ, Bawden CS, Faull RLM, Snell RG.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11293-E11302. doi: 10.1073/pnas.1711243115. Epub 2017 Dec 11.

29.

Rosuvastatin Reduces Aortic Sinus and Coronary Artery Atherosclerosis in SR-B1 (Scavenger Receptor Class B Type 1)/ApoE (Apolipoprotein E) Double Knockout Mice Independently of Plasma Cholesterol Lowering.

Yu P, Xiong T, Tenedero CB, Lebeau P, Ni R, MacDonald ME, Gross PL, Austin RC, Trigatti BL.

Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):26-39. doi: 10.1161/ATVBAHA.117.305140. Epub 2017 Nov 21.

30.

The Making of Informed Choice in Midwifery: A Feminist Experiment in Care.

MacDonald ME.

Cult Med Psychiatry. 2018 Jun;42(2):278-294. doi: 10.1007/s11013-017-9560-9.

PMID:
29143236
31.

HDL protects against doxorubicin-induced cardiotoxicity in a scavenger receptor class B type 1-, PI3K-, and Akt-dependent manner.

Durham KK, Chathely KM, Mak KC, Momen A, Thomas CT, Zhao YY, MacDonald ME, Curtis JM, Husain M, Trigatti BL.

Am J Physiol Heart Circ Physiol. 2018 Jan 1;314(1):H31-H44. doi: 10.1152/ajpheart.00521.2016. Epub 2017 Oct 6.

32.

A modifier of Huntington's disease onset at the MLH1 locus.

Lee JM, Chao MJ, Harold D, Abu Elneel K, Gillis T, Holmans P, Jones L, Orth M, Myers RH, Kwak S, Wheeler VC, MacDonald ME, Gusella JF.

Hum Mol Genet. 2017 Oct 1;26(19):3859-3867. doi: 10.1093/hmg/ddx286.

33.

The conceptualization of childhood in North American pediatric dentistry texts: a discursive case study analysis.

Makansi N, Carnevale FA, Macdonald ME.

Int J Paediatr Dent. 2018 Mar;28(2):189-197. doi: 10.1111/ipd.12325. Epub 2017 Aug 25.

PMID:
28840947
34.

Haplotype-based stratification of Huntington's disease.

Chao MJ, Gillis T, Atwal RS, Mysore JS, Arjomand J, Harold D, Holmans P, Jones L, Orth M, Myers RH, Kwak S, Wheeler VC, MacDonald ME, Gusella JF, Lee JM.

Eur J Hum Genet. 2017 Nov;25(11):1202-1209. doi: 10.1038/ejhg.2017.125. Epub 2017 Aug 23.

35.

Reconciling disparate data to determine the right answer: A grounded theory of meta analysts' reasoning in meta-analysis.

Chan L, Macdonald ME, Carnevale FA, Steele RJ, Shrier I.

Res Synth Methods. 2018 Mar;9(1):25-40. doi: 10.1002/jrsm.1258. Epub 2017 Sep 3.

PMID:
28741808
36.

A randomized phase II trial of geriatric assessment and management for older cancer patients.

Puts MTE, Sattar S, Kulik M, MacDonald ME, McWatters K, Lee K, Brennenstuhl S, Jang R, Amir E, Krzyzanowska MK, Joshua AM, Monette J, Wan-Chow-Wah D, Alibhai SMH.

Support Care Cancer. 2018 Jan;26(1):109-117. doi: 10.1007/s00520-017-3820-7. Epub 2017 Jul 25.

PMID:
28741175
37.

'I'm only dealing with the acute issues': How medical ward 'busyness' constrains care of the dying.

Chan LS, Macdonald ME, Carnevale FA, Cohen SR.

Health (London). 2018 Sep;22(5):451-468. doi: 10.1177/1363459317708822. Epub 2017 May 29.

PMID:
28552003
38.

Erratum to: The concept of 'vulnerability' in research ethics: an in-depth analysis of policies and guidelines.

Bracken-Roche D, Bell E, Macdonald ME, Racine E.

Health Res Policy Syst. 2017 Apr 3;15(1):29. doi: 10.1186/s12961-017-0186-8. No abstract available.

39.

Corrigendum: Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease.

Bragg RM, Coffey SR, Weston RM, Ament SA, Cantle JP, Minnig S, Funk CC, Shuttleworth DD, Woods EL, Sullivan BR, Jones L, Glickenhaus A, Anderson JS, Anderson MD, Dunnett SB, Wheeler VC, MacDonald ME, Brooks SP, Price ND, Carroll JB.

Sci Rep. 2017 Mar 28;7:44960. doi: 10.1038/srep44960. No abstract available.

40.

High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock-in mice across multiple genetic backgrounds.

Ament SA, Pearl JR, Grindeland A, St Claire J, Earls JC, Kovalenko M, Gillis T, Mysore J, Gusella JF, Lee JM, Kwak S, Howland D, Lee MY, Baxter D, Scherler K, Wang K, Geman D, Carroll JB, MacDonald ME, Carlson G, Wheeler VC, Price ND, Hood LE.

Hum Mol Genet. 2017 Mar 1;26(5):913-922. doi: 10.1093/hmg/ddx006.

41.

Inuit interpreters engaged in end-of-life care in Nunavik, Northern Quebec.

Hordyk SR, Macdonald ME, Brassard P.

Int J Circumpolar Health. 2017;76(1):1291868. doi: 10.1080/22423982.2017.1291868.

42.

End-of-Life Care in Nunavik, Quebec: Inuit Experiences, Current Realities, and Ways Forward.

Hordyk SR, Macdonald ME, Brassard P.

J Palliat Med. 2017 Jun;20(6):647-655. doi: 10.1089/jpm.2016.0256. Epub 2017 Feb 8.

PMID:
28177857
43.

Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease.

Bragg RM, Coffey SR, Weston RM, Ament SA, Cantle JP, Minnig S, Funk CC, Shuttleworth DD, Woods EL, Sullivan BR, Jones L, Glickenhaus A, Anderson JS, Anderson MD, Dunnett SB, Wheeler VC, MacDonald ME, Brooks SP, Price ND, Carroll JB.

Sci Rep. 2017 Feb 8;7:41570. doi: 10.1038/srep41570. Erratum in: Sci Rep. 2017 Mar 28;7:44960.

44.

The concept of 'vulnerability' in research ethics: an in-depth analysis of policies and guidelines.

Bracken-Roche D, Bell E, Macdonald ME, Racine E.

Health Res Policy Syst. 2017 Feb 7;15(1):8. doi: 10.1186/s12961-016-0164-6. Erratum in: Health Res Policy Syst. 2017 Apr 3;15(1):29.

45.

Permanent inactivation of Huntington's disease mutation by personalized allele-specific CRISPR/Cas9.

Shin JW, Kim KH, Chao MJ, Atwal RS, Gillis T, MacDonald ME, Gusella JF, Lee JM.

Hum Mol Genet. 2016 Oct 15;25(20):4566-4576. doi: 10.1093/hmg/ddw286.

46.

Novel allele-specific quantification methods reveal no effects of adult onset CAG repeats on HTT mRNA and protein levels.

Shin A, Shin B, Shin JW, Kim KH, Atwal RS, Hope JM, Gillis T, Leszyk JD, Shaffer SA, Lee R, Kwak S, MacDonald ME, Gusella JF, Seong IS, Lee JM.

Hum Mol Genet. 2017 Apr 1;26(7):1258-1267. doi: 10.1093/hmg/ddx033.

47.

Potential molecular consequences of transgene integration: The R6/2 mouse example.

Jacobsen JC, Erdin S, Chiang C, Hanscom C, Handley RR, Barker DD, Stortchevoi A, Blumenthal I, Reid SJ, Snell RG, MacDonald ME, Morton AJ, Ernst C, Gusella JF, Talkowski ME.

Sci Rep. 2017 Jan 25;7:41120. doi: 10.1038/srep41120.

48.

Highly Expandable Human iPS Cell-Derived Neural Progenitor Cells (NPC) and Neurons for Central Nervous System Disease Modeling and High-Throughput Screening.

Cheng C, Fass DM, Folz-Donahue K, MacDonald ME, Haggarty SJ.

Curr Protoc Hum Genet. 2017 Jan 11;92:21.8.1-21.8.21. doi: 10.1002/cphg.33.

49.

Patient participation in palliative care decisions: An ethnographic discourse analysis.

Bélanger E, Rodríguez C, Groleau D, Légaré F, MacDonald ME, Marchand R.

Int J Qual Stud Health Well-being. 2016 Nov 22;11:32438. doi: 10.3402/qhw.v11.32438. eCollection 2016.

50.

Chemotherapy treatment decision-making experiences of older adults with cancer, their family members, oncologists and family physicians: a mixed methods study.

Puts MT, Sattar S, McWatters K, Lee K, Kulik M, MacDonald ME, Jang R, Amir E, Krzyzanowska MK, Leighl N, Fitch M, Joshua AM, Warde P, Tourangeau AE, Alibhai SM.

Support Care Cancer. 2017 Mar;25(3):879-886. doi: 10.1007/s00520-016-3476-8. Epub 2016 Nov 9.

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