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Items: 1 to 50 of 53

1.

Rapid acquisition and model-based analysis of cell-free transcription-translation reactions from nonmodel bacteria.

Moore SJ, MacDonald JT, Wienecke S, Ishwarbhai A, Tsipa A, Aw R, Kylilis N, Bell DJ, McClymont DW, Jensen K, Polizzi KM, Biedendieck R, Freemont PS.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4340-E4349. doi: 10.1073/pnas.1715806115. Epub 2018 Apr 17.

2.

Tantrums, Emotion Reactions and Their EEG Correlates in Childhood Benign Rolandic Epilepsy vs. Complex Partial Seizures: Exploratory Observations.

Potegal M, Drewel EH, MacDonald JT.

Front Behav Neurosci. 2018 Mar 9;12:40. doi: 10.3389/fnbeh.2018.00040. eCollection 2018.

3.

Atomic Structure of Type VI Contractile Sheath from Pseudomonas aeruginosa.

Salih O, He S, Planamente S, Stach L, MacDonald JT, Manoli E, Scheres SHW, Filloux A, Freemont PS.

Structure. 2018 Feb 6;26(2):329-336.e3. doi: 10.1016/j.str.2017.12.005. Epub 2018 Jan 4.

4.

Effect of Standardized Handoff Curriculum on Improved Clinician Preparedness in the Intensive Care Unit: A Stepped-Wedge Cluster Randomized Clinical Trial.

Parent B, LaGrone LN, Albirair MT, Serina PT, Keller JM, Cuschieri J, Addison EJ, Choe L, Delossantos GB, Gaskill CE, Moon SD, MacDonald JT, Stolzberg MJ, Van Eaton EG, Zech JM, Kritek PA.

JAMA Surg. 2018 May 1;153(5):464-470. doi: 10.1001/jamasurg.2017.5440.

5.

Computational Sequence Design with R2oDNA Designer.

MacDonald JT, Siciliano V.

Methods Mol Biol. 2017;1651:249-262. doi: 10.1007/978-1-4939-7223-4_18.

PMID:
28801912
6.

Cell-free synthetic biology for in vitro prototype engineering.

Moore SJ, MacDonald JT, Freemont PS.

Biochem Soc Trans. 2017 Jun 15;45(3):785-791. doi: 10.1042/BST20170011. Review.

7.

Computational protein design with backbone plasticity.

MacDonald JT, Freemont PS.

Biochem Soc Trans. 2016 Oct 15;44(5):1523-1529. Epub 2016 Oct 19. Review.

8.

Infantile Epileptic Encephalopathy Associated With SCN2A Mutation Responsive to Oral Mexiletine.

Foster LA, Johnson MR, MacDonald JT, Karachunski PI, Henry TR, Nascene DR, Moran BP, Raymond GV.

Pediatr Neurol. 2017 Jan;66:108-111. doi: 10.1016/j.pediatrneurol.2016.10.008. Epub 2016 Oct 18.

PMID:
27867041
9.

Development of a Bacillus subtilis cell-free transcription-translation system for prototyping regulatory elements.

Kelwick R, Webb AJ, MacDonald JT, Freemont PS.

Metab Eng. 2016 Nov;38:370-381. doi: 10.1016/j.ymben.2016.09.008. Epub 2016 Sep 30.

10.

Synthetic beta-solenoid proteins with the fragment-free computational design of a beta-hairpin extension.

MacDonald JT, Kabasakal BV, Godding D, Kraatz S, Henderson L, Barber J, Freemont PS, Murray JW.

Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10346-51. doi: 10.1073/pnas.1525308113. Epub 2016 Aug 29.

11.

A protease-based biosensor for the detection of schistosome cercariae.

Webb AJ, Kelwick R, Doenhoff MJ, Kylilis N, MacDonald JT, Wen KY, McKeown C, Baldwin G, Ellis T, Jensen K, Freemont PS.

Sci Rep. 2016 Apr 19;6:24725. doi: 10.1038/srep24725.

12.

Delineation of metabolic gene clusters in plant genomes by chromatin signatures.

Yu N, Nützmann HW, MacDonald JT, Moore B, Field B, Berriri S, Trick M, Rosser SJ, Kumar SV, Freemont PS, Osbourn A.

Nucleic Acids Res. 2016 Mar 18;44(5):2255-65. doi: 10.1093/nar/gkw100. Epub 2016 Feb 18.

13.

Developments in the tools and methodologies of synthetic biology.

Kelwick R, MacDonald JT, Webb AJ, Freemont P.

Front Bioeng Biotechnol. 2014 Nov 26;2:60. doi: 10.3389/fbioe.2014.00060. eCollection 2014. Review.

14.

Structural and mechanistic insight into the Listeria monocytogenes two-enzyme lipoteichoic acid synthesis system.

Campeotto I, Percy MG, MacDonald JT, Förster A, Freemont PS, Gründling A.

J Biol Chem. 2014 Oct 10;289(41):28054-69. doi: 10.1074/jbc.M114.590570. Epub 2014 Aug 15.

15.

R2oDNA designer: computational design of biologically neutral synthetic DNA sequences.

Casini A, Christodoulou G, Freemont PS, Baldwin GS, Ellis T, MacDonald JT.

ACS Synth Biol. 2014 Aug 15;3(8):525-8. doi: 10.1021/sb4001323. Epub 2014 Feb 11.

PMID:
24933158
16.

One-pot DNA construction for synthetic biology: the Modular Overlap-Directed Assembly with Linkers (MODAL) strategy.

Casini A, MacDonald JT, De Jonghe J, Christodoulou G, Freemont PS, Baldwin GS, Ellis T.

Nucleic Acids Res. 2014 Jan;42(1):e7. doi: 10.1093/nar/gkt915. Epub 2013 Oct 22.

17.

Validating a Coarse-Grained Potential Energy Function through Protein Loop Modelling.

Macdonald JT, Kelley LA, Freemont PS.

PLoS One. 2013 Jun 18;8(6):e65770. doi: 10.1371/journal.pone.0065770. Print 2013.

18.

High-quality protein backbone reconstruction from alpha carbons using Gaussian mixture models.

Moore BL, Kelley LA, Barber J, Murray JW, MacDonald JT.

J Comput Chem. 2013 Aug 15;34(22):1881-9. doi: 10.1002/jcc.23330. Epub 2013 May 24.

PMID:
23703289
19.

Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.

Lu D, Silhan J, MacDonald JT, Carpenter EP, Jensen K, Tang CM, Baldwin GS, Freemont PS.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16852-7. doi: 10.1073/pnas.1206563109. Epub 2012 Oct 3.

20.

Analytic markovian rates for generalized protein structure evolution.

Coluzza I, MacDonald JT, Sadowski MI, Taylor WR, Goldstein RA.

PLoS One. 2012;7(5):e34228. doi: 10.1371/journal.pone.0034228. Epub 2012 May 23.

21.

Anniversary of the Christchurch earthquake.

MacDonald JT.

BJU Int. 2012 Apr;109 Suppl 3:7. doi: 10.1111/j.1464-410X.2012.11035.x. No abstract available.

22.

Reading skills in children and adults with albinism: the role of visual impairment.

MacDonald JT, Kutzbach BR, Holleschau AM, Wyckoff S, Summers CG.

J Pediatr Ophthalmol Strabismus. 2012 May-Jun;49(3):184-8. doi: 10.3928/01913913-20111101-03. Epub 2011 Nov 8.

PMID:
22074358
23.

Reading acuity in albinism: evaluation with MNREAD charts.

Merrill K, Hogue K, Downes S, Holleschau AM, Kutzbach BR, MacDonald JT, Summers CG.

J AAPOS. 2011 Feb;15(1):29-32. doi: 10.1016/j.jaapos.2010.12.005.

PMID:
21397802
24.

Computational design approaches and tools for synthetic biology.

MacDonald JT, Barnes C, Kitney RI, Freemont PS, Stan GB.

Integr Biol (Camb). 2011 Feb;3(2):97-108. doi: 10.1039/c0ib00077a. Epub 2011 Jan 24. Review.

PMID:
21258712
25.

De novo backbone scaffolds for protein design.

MacDonald JT, Maksimiak K, Sadowski MI, Taylor WR.

Proteins. 2010 Apr;78(5):1311-25. doi: 10.1002/prot.22651.

26.

Probing the "dark matter" of protein fold space.

Taylor WR, Chelliah V, Hollup SM, MacDonald JT, Jonassen I.

Structure. 2009 Sep 9;17(9):1244-52. doi: 10.1016/j.str.2009.07.012.

27.

Evaluation of vision-specific quality-of-life in albinism.

Kutzbach BR, Merrill KS, Hogue KM, Downes SJ, Holleschau AM, MacDonald JT, Summers CG.

J AAPOS. 2009 Apr;13(2):191-5. doi: 10.1016/j.jaapos.2008.10.008. Epub 2009 Jan 20.

PMID:
19157938
28.

Neurodevelopment in children with albinism.

Kutzbach BR, Summers CG, Holleschau AM, MacDonald JT.

Ophthalmology. 2008 Oct;115(10):1805-8, 1808.e1-2. doi: 10.1016/j.ophtha.2008.03.006. Epub 2008 Apr 28.

PMID:
18440642
29.

The prevalence of attention-deficit/hyperactivity disorder among persons with albinism.

Kutzbach B, Summers CG, Holleschau AM, King RA, MacDonald JT.

J Child Neurol. 2007 Dec;22(12):1342-7. doi: 10.1177/0883073807307078.

PMID:
18174549
30.

Objective tinnitus due to essential palatal tremor in a 5-year-old.

MacDonald JT.

Pediatr Neurol. 2007 Mar;36(3):175-6.

PMID:
17352951
31.

Comment on: Loureiro & Rozenfeld "Epidemiology of sickle cell disease hospital admissions in Brazil".

Wierenga KJ, Hambleton IR.

Rev Saude Publica. 2006 Aug;40(4):740-1; author reply 741. No abstract available. Erratum in: Rev Saude Publica. 2006 Oct;40(5):946. Macdonald, John T [removed]; Loureiro, Monique M [removed]; Rozenfeld, Suely [removed]; Hambleton, Ian R [added].

32.

Mutation in ROBO3 gene recently documented in patients with horizontal gaze palsy with progressive scoliosis.

MacDonald JT.

J Child Neurol. 2006 Jun;21(6):545. No abstract available.

PMID:
16948950
33.

Unfolding crystallins: the destabilizing role of a beta-hairpin cysteine in betaB2-crystallin by simulation and experiment.

MacDonald JT, Purkiss AG, Smith MA, Evans P, Goodfellow JM, Slingsby C.

Protein Sci. 2005 May;14(5):1282-92.

34.

Repeat urethrotomy and dilation for the treatment of urethral stricture are neither clinically effective nor cost-effective.

Greenwell TJ, Castle C, Andrich DE, MacDonald JT, Nicol DL, Mundy AR.

J Urol. 2004 Jul;172(1):275-7.

PMID:
15201793
35.

Prolonged but reversible respiratory failure in a newborn with Prader-Willi syndrome.

MacDonald JT, Camp D.

J Child Neurol. 2001 Feb;16(2):153-4.

PMID:
11292227
36.

Identifying a new reality: zero vascular access recirculation using ultrasound dilution.

MacDonald JT, Sosa MA, Krivitski NM, Glidden D, Sands JJ.

ANNA J. 1996 Dec;23(6):603-8, 635. Review.

PMID:
9069789
37.

Treatment of juvenile migraine with subcutaneous sumatriptan.

MacDonald JT.

Headache. 1994 Nov-Dec;34(10):581-2.

PMID:
7843952
38.

Vision despite tomographic absence of the occipital cortex.

Summers CG, MacDonald JT.

Surv Ophthalmol. 1990 Nov-Dec;35(3):188-90.

PMID:
2274848
39.

Paroxysmal facial itch: a presenting sign of childhood brainstem glioma.

Summers CG, MacDonald JT.

J Child Neurol. 1988 Jul;3(3):189-92.

PMID:
3145300
40.

Childhood seizures. Individualized treatment based on type.

MacDonald JT.

Postgrad Med. 1988 Apr;83(5):79-80, 85-7, 90-2.

PMID:
3357873
41.

Breakthrough seizure following substitution of Depakene capsules (Abbott) with a generic product.

MacDonald JT.

Neurology. 1987 Dec;37(12):1885. No abstract available.

PMID:
3120036
42.

Ocular motor apraxia associated with intracranial lipoma.

Summers CG, MacDonald JT, Wirtschafter JD.

J Pediatr Ophthalmol Strabismus. 1987 Sep-Oct;24(5):267-9.

PMID:
3681617
43.

Comparison of self-hypnosis and propranolol in the treatment of juvenile classic migraine.

Olness K, MacDonald JT, Uden DL.

Pediatrics. 1987 Apr;79(4):593-7.

PMID:
3822681
44.

Recurrent headaches in children: diagnosis and treatment.

Olness KN, MacDonald JT.

Pediatr Rev. 1987 Apr;8(10):307-11. Review. No abstract available.

PMID:
3332334
45.

Childhood migraine. Differential diagnosis and treatment.

MacDonald JT.

Postgrad Med. 1986 Oct;80(5):301-4, 306.

PMID:
3763532
46.
47.

Adrenoleukodystrophy: early frontal lobe involvement on computed tomography.

MacDonald JT, Stauffer AE, Heitoff K.

J Comput Assist Tomogr. 1984 Feb;8(1):128-30.

PMID:
6690495
48.

Susceptibility of Pasteurella haemolytica to the bactericidal effects of serum, nasal secretions and bronchoalveolar washings from cattle.

MacDonald JT, Maheswaran SK, Opuda-Asibo J, Townsend EL, Thies ES.

Vet Microbiol. 1983 Nov;8(6):585-99.

PMID:
6419445
49.

Intravenous glycerol and mannitol therapy in children with intracranial hypertension.

MacDonald JT, Uden DL.

Neurology. 1982 Apr;32(4):437-40.

PMID:
6801542
50.

Acute hemiparesis in juvenile insulin-dependent diabetes mellitus (JIDDM).

MacDonald JT, Brown DR.

Neurology. 1979 Jun;29(6):893-6.

PMID:
572016

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