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Items: 1 to 50 of 257

1.

A nanoscale, multi-parametric flow cytometry-based platform to study mitochondrial heterogeneity and mitochondrial DNA dynamics.

MacDonald JA, Bothun AM, Annis SN, Sheehan H, Ray S, Gao Y, Ivanov AR, Khrapko K, Tilly JL, Woods DC.

Commun Biol. 2019 Jul 11;2:258. doi: 10.1038/s42003-019-0513-4. eCollection 2019.

2.

Inflammasomes: Intracellular mediators of immune defense.

MacDonald JA.

Arch Biochem Biophys. 2019 Jul 30;670:1-3. doi: 10.1016/j.abb.2019.07.001. Epub 2019 Jul 2. No abstract available.

PMID:
31271733
3.

A comparison of longitudinal modelling approaches: Alcohol and cannabis use from adolescence to young adulthood.

Greenwood CJ, Youssef GJ, Betts KS, Letcher P, Mcintosh J, Spry E, Hutchinson DM, Macdonald JA, Hagg LJ, Sanson A, Toumbourou JW, Olsson CA.

Drug Alcohol Depend. 2019 Aug 1;201:58-64. doi: 10.1016/j.drugalcdep.2019.05.001. Epub 2019 May 29.

PMID:
31195345
4.

Pregnane X Receptor Activation Triggers Rapid ATP Release in Primed Macrophages That Mediates NLRP3 Inflammasome Activation.

Hudson G, Flannigan KL, Venu VKP, Alston L, Sandall CF, MacDonald JA, Muruve DA, Chang TKH, Mani S, Hirota SA.

J Pharmacol Exp Ther. 2019 Jul;370(1):44-53. doi: 10.1124/jpet.118.255679. Epub 2019 Apr 19.

5.

Maternal mental health and infant emotional reactivity: a 20-year two-cohort study of preconception and perinatal exposures.

Spry E, Moreno-Betancur M, Becker D, Romaniuk H, Carlin JB, Molyneaux E, Howard LM, Ryan J, Letcher P, McIntosh J, Macdonald JA, Greenwood CJ, Thomson KC, McAnally H, Hancox R, Hutchinson DM, Youssef GJ, Olsson CA, Patton GC.

Psychol Med. 2019 Apr 10:1-11. doi: 10.1017/S0033291719000709. [Epub ahead of print]

PMID:
30968786
6.

Neuropathological changes and cognitive deficits in rats transgenic for human mutant tau recapitulate human tauopathy.

Malcolm JC, Breuillaud L, Do Carmo S, Hall H, Welikovitch LA, Macdonald JA, Goedert M, Cuello AC.

Neurobiol Dis. 2019 Jul;127:323-338. doi: 10.1016/j.nbd.2019.03.018. Epub 2019 Mar 21.

7.

Assembly of transgenic human P301S Tau is necessary for neurodegeneration in murine spinal cord.

Macdonald JA, Bronner IF, Drynan L, Fan J, Curry A, Fraser G, Lavenir I, Goedert M.

Acta Neuropathol Commun. 2019 Mar 18;7(1):44. doi: 10.1186/s40478-019-0695-5.

8.

Extracellular matrix signaling activates differentiation of adult ovary-derived oogonial stem cells in a species-specific manner.

MacDonald JA, Takai Y, Ishihara O, Seki H, Woods DC, Tilly JL.

Fertil Steril. 2019 Apr;111(4):794-805. doi: 10.1016/j.fertnstert.2018.12.015. Epub 2019 Mar 11.

PMID:
30871765
9.

Effects of phosphorylation on the NLRP3 inflammasome.

Sandall CF, MacDonald JA.

Arch Biochem Biophys. 2019 Jul 30;670:43-57. doi: 10.1016/j.abb.2019.02.020. Epub 2019 Mar 5. Review.

PMID:
30844378
10.

Analyzing Recombinant Protein Production in Pichia pastoris with Targeted Proteomics.

Bill RM, Ulke-Lemée A, Cartwright SP, Far R, Kim J, MacDonald JA.

Methods Mol Biol. 2019;1923:187-209. doi: 10.1007/978-1-4939-9024-5_8.

PMID:
30737741
11.

Smoothelin-like 1 deletion enhances myogenic reactivity of mesenteric arteries with alterations in PKC and myosin phosphatase signaling.

Turner SR, Chappellaz M, Popowich B, Wooldridge AA, Haystead TAJ, Cole WC, MacDonald JA.

Sci Rep. 2019 Jan 24;9(1):481. doi: 10.1038/s41598-018-36564-0.

12.

Application of immobilized ATP to the study of NLRP inflammasomes.

Liao KC, Sandall CF, Carlson DA, Ulke-Lemée A, Platnich JM, Hughes PF, Muruve DA, Haystead TAJ, MacDonald JA.

Arch Biochem Biophys. 2019 Jul 30;670:104-115. doi: 10.1016/j.abb.2018.12.031. Epub 2019 Jan 11.

PMID:
30641048
13.

Tools and protocol for quantification of myosin phosphorylation with MRM-MS.

MacDonald JA, Ulke-Lemée A, Chappellaz M, Segboer H.

MethodsX. 2018 May 17;5:466-474. doi: 10.1016/j.mex.2018.05.004. eCollection 2018.

14.

Adolescent Care-Orientation and Positive Development in Young Adulthood.

Hutchinson D, Youssef GJ, Buhagiar A, Teague S, Macdonald JA, Letcher P, Greenwood C, McIntosh J, Toumbourou JW, Hallam BWT, Skouteris H, Sanson A, Olsson CA.

J Adolesc Health. 2019 Jan;64(1):63-69. doi: 10.1016/j.jadohealth.2018.07.024.

PMID:
30579438
15.

MRI assessment of aortic flow in patients with pulmonary arterial hypertension in response to exercise.

Macdonald JA, Franҫois CJ, Forouzan O, Chesler NC, Wieben O.

BMC Med Imaging. 2018 Dec 22;18(1):55. doi: 10.1186/s12880-018-0298-9.

16.

Pre-conception self-harm, maternal mental health and mother-infant bonding problems: a 20-year prospective cohort study.

Borschmann R, Molyneaux E, Spry E, Moran P, Howard LM, Macdonald JA, Brown SJ, Moreno-Betancur M, Olsson CA, Patton GC.

Psychol Med. 2018 Dec 18:1-9. doi: 10.1017/S0033291718003689. [Epub ahead of print]

PMID:
30560741
17.

Retention strategies in longitudinal cohort studies: a systematic review and meta-analysis.

Teague S, Youssef GJ, Macdonald JA, Sciberras E, Shatte A, Fuller-Tyszkiewicz M, Greenwood C, McIntosh J, Olsson CA, Hutchinson D; SEED Lifecourse Sciences Theme.

BMC Med Res Methodol. 2018 Nov 26;18(1):151. doi: 10.1186/s12874-018-0586-7.

18.

Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome.

Platnich JM, Chung H, Lau A, Sandall CF, Bondzi-Simpson A, Chen HM, Komada T, Trotman-Grant AC, Brandelli JR, Chun J, Beck PL, Philpott DJ, Girardin SE, Ho M, Johnson RP, MacDonald JA, Armstrong GD, Muruve DA.

Cell Rep. 2018 Nov 6;25(6):1525-1536.e7. doi: 10.1016/j.celrep.2018.09.071.

19.

Validation of chemical genetics for the study of zipper-interacting protein kinase signaling.

Al-Ghabkari A, Moffat LD, Walsh MP, MacDonald JA.

Proteins. 2018 Nov;86(11):1211-1217. doi: 10.1002/prot.25607. Epub 2018 Nov 1.

PMID:
30381843
20.

Mitochondrial membrane depolarization enhances TRAIL-induced cell death in adult human granulosa tumor cells, KGN, through inhibition of BIRC5.

MacDonald JA, Kura N, Sussman C, Woods DC.

J Ovarian Res. 2018 Oct 16;11(1):89. doi: 10.1186/s13048-018-0463-3.

21.

Trends in cannabis use over time among Canadian youth: 2004-2014.

Leos-Toro C, Rynard V, Murnaghan D, MacDonald JA, Hammond D.

Prev Med. 2019 Jan;118:30-37. doi: 10.1016/j.ypmed.2018.10.002. Epub 2018 Oct 11.

PMID:
30316874
22.

Psychosocial profiles of adolescents from dissolved families: Differences in depressive symptoms in emerging adulthood.

Di Manno L, Macdonald JA, Youssef GJ, Little K, Olsson CA.

J Affect Disord. 2018 Dec 1;241:325-337. doi: 10.1016/j.jad.2018.07.087. Epub 2018 Aug 8.

PMID:
30142592
23.

Uteroplacental and Fetal 4D Flow MRI in the Pregnant Rhesus Macaque.

Macdonald JA, Corrado PA, Nguyen SM, Johnson KM, Francois CJ, Magness RR, Shah DM, Golos TG, Wieben O.

J Magn Reson Imaging. 2019 Feb;49(2):534-545. doi: 10.1002/jmri.26206. Epub 2018 Aug 13.

PMID:
30102431
24.

Targeting Pim Kinases and DAPK3 to Control Hypertension.

Carlson DA, Singer MR, Sutherland C, Redondo C, Alexander LT, Hughes PF, Knapp S, Gurley SB, Sparks MA, MacDonald JA, Haystead TAJ.

Cell Chem Biol. 2018 Oct 18;25(10):1195-1207.e32. doi: 10.1016/j.chembiol.2018.06.006. Epub 2018 Jul 19.

PMID:
30033129
25.

A method for freeze-fracture and scanning electron microscopy of isolated mitochondria.

MacDonald JA, Fowle WH, Shin E, Woods DC.

MethodsX. 2018 May 19;5:593-598. doi: 10.1016/j.mex.2018.05.006. eCollection 2018.

26.

Quantification of Inflammasome Adaptor Protein ASC in Biological Samples by Multiple-Reaction Monitoring Mass Spectrometry.

Ulke-Lemée A, Lau A, Nelson MC, James MT, Muruve DA, MacDonald JA.

Inflammation. 2018 Aug;41(4):1396-1408. doi: 10.1007/s10753-018-0787-6.

PMID:
29948504
27.

Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury.

Lau A, Chung H, Komada T, Platnich JM, Sandall CF, Choudhury SR, Chun J, Naumenko V, Surewaard BG, Nelson MC, Ulke-Lemée A, Beck PL, Benediktsson H, Jevnikar AM, Snelgrove SL, Hickey MJ, Senger DL, James MT, Macdonald JA, Kubes P, Jenne CN, Muruve DA.

J Clin Invest. 2018 Jul 2;128(7):2894-2913. doi: 10.1172/JCI96640. Epub 2018 Jun 4.

28.

Performing Inferential Statistics Prior to Data Collection.

Trafimow D, MacDonald JA.

Educ Psychol Meas. 2017 Apr;77(2):204-219. doi: 10.1177/0013164416659745. Epub 2016 Jul 13.

29.

Regulation of Smooth Muscle Myosin Light Chain Phosphatase by Multisite Phosphorylation of the Myosin Targeting Subunit, MYPT1.

MacDonald JA, Walsh MP.

Cardiovasc Hematol Disord Drug Targets. 2018;18(1):4-13. doi: 10.2174/1871529X18666180326120638. Review.

PMID:
29577868
30.

Quantitation of myosin regulatory light chain phosphorylation in biological samples with multiple reaction monitoring mass spectrometry.

Chappellaz M, Segboer H, Ulke-Lemée A, Sutherland C, Chen HM, MacDonald JA.

Biochim Biophys Acta Proteins Proteom. 2018 May - Jun;1866(5-6):608-616. doi: 10.1016/j.bbapap.2018.03.008. Epub 2018 Mar 19.

PMID:
29567090
31.

Smoothelins and the Control of Muscle Contractility.

Murali M, MacDonald JA.

Adv Pharmacol. 2018;81:39-78. doi: 10.1016/bs.apha.2017.10.001. Epub 2017 Dec 2. Review.

PMID:
29310803
32.

Differential mechanisms of adenosine- and ATPγS-induced microvascular endothelial barrier strengthening.

Bátori R, Kumar S, Bordán Z, Cherian-Shaw M, Kovács-Kása A, MacDonald JA, Fulton DJR, Erdődi F, Verin AD.

J Cell Physiol. 2019 May;234(5):5863-5879. doi: 10.1002/jcp.26419. Epub 2018 Dec 17.

PMID:
29271489
33.

Sometimes It's Good to be Short: The Serotonin Transporter Gene, Positive Parenting, and Adolescent Depression.

Little K, Olsson CA, Whittle S, Macdonald JA, Sheeber LB, Youssef GJ, Simmons JG, Sanson AV, Foley DL, Allen NB.

Child Dev. 2019 Jul;90(4):1061-1079. doi: 10.1111/cdev.12987. Epub 2017 Nov 2.

PMID:
29094757
34.

The parental bonds of adolescent girls and next-generation maternal-infant bonding: findings from the Victorian Intergenerational Health Cohort Study.

Macdonald JA, Youssef GJ, Phillips L, Spry E, Alway Y, Patton GC, Olsson CA.

Arch Womens Ment Health. 2018 Apr;21(2):171-180. doi: 10.1007/s00737-017-0778-x. Epub 2017 Sep 20.

PMID:
28932997
35.

New insights on mitochondrial heterogeneity observed in prepared mitochondrial samples following a method for freeze-fracture and scanning electron microscopy.

MacDonald JA, Fowle WH, Woods PhD DC.

Micron. 2017 Oct;101:25-31. doi: 10.1016/j.micron.2017.05.002. Epub 2017 Jun 1.

PMID:
28609725
36.

Binding of smoothelin-like 1 to tropomyosin and calmodulin is mutually exclusive and regulated by phosphorylation.

Ulke-Lemée A, Sun DH, Ishida H, Vogel HJ, MacDonald JA.

BMC Biochem. 2017 Mar 21;18(1):5. doi: 10.1186/s12858-017-0080-6.

37.

Maternal Bonding through Pregnancy and Postnatal: Findings from an Australian Longitudinal Study.

Rossen L, Hutchinson D, Wilson J, Burns L, Allsop S, Elliott EJ, Jacobs S, Macdonald JA, Olsson C, Mattick RP.

Am J Perinatol. 2017 Jul;34(8):808-817. doi: 10.1055/s-0037-1599052. Epub 2017 Feb 17.

PMID:
28212591
38.

Erratum to "Family dissolution and offspring depression and depressive symptoms: A systematic review of moderation effects" [J. Affect. Disord. 188 (2015) 68-79].

Di Manno L, Macdonald JA, Knight T.

J Affect Disord. 2016 Nov 15;205:138. doi: 10.1016/j.jad.2016.06.056. Epub 2016 Jul 19. No abstract available.

PMID:
27692289
39.

Exaggerated IL-15 and Altered Expression of foxp3+ Cell-Derived Cytokines Contribute to Enhanced Colitis in Nlrp3-/- Mice.

Hirota SA, Ueno A, Tulk SE, Becker HM, Schenck LP, Potentier MS, Li Y, Ghosh S, Muruve DA, MacDonald JA, Beck PL.

Mediators Inflamm. 2016;2016:5637685. doi: 10.1155/2016/5637685. Epub 2016 Aug 17.

40.

A novel inhibitory effect of oxazol-5-one compounds on ROCKII signaling in human coronary artery vascular smooth muscle cells.

Al-Ghabkari A, Deng JT, McDonald PC, Dedhar S, Alshehri M, Walsh MP, MacDonald JA.

Sci Rep. 2016 Aug 30;6:32118. doi: 10.1038/srep32118.

41.

NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations.

Mortimer L, Moreau F, MacDonald JA, Chadee K.

Nat Immunol. 2016 Oct;17(10):1176-86. doi: 10.1038/ni.3538. Epub 2016 Aug 22.

PMID:
27548431
42.

The natural history of internalizing behaviours from adolescence to emerging adulthood: findings from the Australian Temperament Project.

Betts KS, Baker P, Alati R, McIntosh JE, Macdonald JA, Letcher P, Olsson CA.

Psychol Med. 2016 Oct;46(13):2815-27. doi: 10.1017/S0033291716001495. Epub 2016 Jul 21.

PMID:
27439384
43.

Associations between parent-child relationship quality and obesogenic risk in adolescence: a systematic review of recent literature.

Blewitt C, Bergmeier H, Macdonald JA, Olsson CA, Skouteris H.

Obes Rev. 2016 Jul;17(7):612-22. doi: 10.1111/obr.12413. Epub 2016 Apr 29. Review.

PMID:
27125464
44.

Predictors of postnatal mother-infant bonding: the role of antenatal bonding, maternal substance use and mental health.

Rossen L, Hutchinson D, Wilson J, Burns L, A Olsson C, Allsop S, J Elliott E, Jacobs S, Macdonald JA, Mattick RP.

Arch Womens Ment Health. 2016 Aug;19(4):609-22. doi: 10.1007/s00737-016-0602-z. Epub 2016 Feb 11.

PMID:
26867547
45.

Analysis of phosphorylation of the myosin-targeting subunit of myosin light chain phosphatase by Phos-tag SDS-PAGE.

Sutherland C, MacDonald JA, Walsh MP.

Am J Physiol Cell Physiol. 2016 Apr 15;310(8):C681-91. doi: 10.1152/ajpcell.00327.2015. Epub 2016 Feb 10.

46.

Assessing health program performance in low- and middle-income countries: building a feasible, credible, and comprehensive framework.

Bhattacharyya O, Mossman K, Ginther J, Hayden L, Sohal R, Cha J, Bopardikar A, MacDonald JA, Parikh H, Shahin I, McGahan A, Mitchell W.

Global Health. 2015 Dec 21;11:51. doi: 10.1186/s12992-015-0137-5.

47.

Gastrointestinal dysbiosis and the use of fecal microbial transplantation in Clostridium difficile infection.

Schenck LP, Beck PL, MacDonald JA.

World J Gastrointest Pathophysiol. 2015 Nov 15;6(4):169-80. doi: 10.4291/wjgp.v6.i4.169. Review.

48.

Relationships between problematic alcohol consumption and delinquent behaviour from adolescence to young adulthood.

Miller PG, Butler E, Richardson B, Staiger PK, Youssef GJ, Macdonald JA, Sanson A, Edwards B, Olsson CA.

Drug Alcohol Rev. 2016 May;35(3):317-25. doi: 10.1111/dar.12345. Epub 2015 Oct 23.

PMID:
26494311
49.

A Small Molecule Pyrazolo[3,4-d]Pyrimidinone Inhibitor of Zipper-Interacting Protein Kinase Suppresses Calcium Sensitization of Vascular Smooth Muscle.

MacDonald JA, Sutherland C, Carlson DA, Bhaidani S, Al-Ghabkari A, Swärd K, Haystead TA, Walsh MP.

Mol Pharmacol. 2016 Jan;89(1):105-17. doi: 10.1124/mol.115.100529. Epub 2015 Oct 13.

PMID:
26464323
50.

A prospective observational study of needle-handling practices at a University Veterinary Teaching Hospital.

Riley CB, McCallum S, MacDonald JA, Hill KE.

N Z Vet J. 2016 Mar;64(2):117-20. doi: 10.1080/00480169.2015.1100100. Epub 2015 Nov 10.

PMID:
26425795

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