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Items: 1 to 50 of 86

1.

Tools and applications in synthetic biology.

MacDonald IC, Deans TL.

Adv Drug Deliv Rev. 2016 Oct 1;105(Pt A):20-34. doi: 10.1016/j.addr.2016.08.008. Epub 2016 Aug 25. Review.

PMID:
27568463
2.

Antibiotics induce redox-related physiological alterations as part of their lethality.

Dwyer DJ, Belenky PA, Yang JH, MacDonald IC, Martell JD, Takahashi N, Chan CT, Lobritz MA, Braff D, Schwarz EG, Ye JD, Pati M, Vercruysse M, Ralifo PS, Allison KR, Khalil AS, Ting AY, Walker GC, Collins JJ.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2100-9. doi: 10.1073/pnas.1401876111. Epub 2014 May 6.

3.

A method to validate quantitative high-frequency power doppler ultrasound with fluorescence in vivo video microscopy.

Pinter SZ, Kim DR, Hague MN, Chambers AF, MacDonald IC, Lacefield JC.

Ultrasound Med Biol. 2014 Aug;40(8):1908-17. doi: 10.1016/j.ultrasmedbio.2014.02.030. Epub 2014 May 3.

PMID:
24798391
4.

Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production.

Brynildsen MP, Winkler JA, Spina CS, MacDonald IC, Collins JJ.

Nat Biotechnol. 2013 Feb;31(2):160-5. doi: 10.1038/nbt.2458. Epub 2013 Jan 6.

5.

Effect of (S)-3,5-DHPG on microRNA expression in mouse brain.

Lusardi TA, Thompson SJ, MacDonald IC, Lan JQ, Theofilas P, Saugstad JA.

Exp Neurol. 2012 Jun;235(2):497-507. doi: 10.1016/j.expneurol.2012.01.018. Epub 2012 Jan 28.

6.

The synthetic triterpenoid CDDO-Imidazolide suppresses experimental liver metastasis.

Townson JL, Macdonald IC, Liby KT, Mackenzie L, Dales DW, Hedley BD, Foster PJ, Sporn MB, Chambers AF.

Clin Exp Metastasis. 2011 Mar;28(3):309-17. doi: 10.1007/s10585-011-9374-z. Epub 2011 Jan 15.

PMID:
21234655
7.

Three-dimensional imaging and quantification of both solitary cells and metastases in whole mouse liver by magnetic resonance imaging.

Townson JL, Ramadan SS, Simedrea C, Rutt BK, MacDonald IC, Foster PJ, Chambers AF.

Cancer Res. 2009 Nov 1;69(21):8326-31. doi: 10.1158/0008-5472.CAN-09-1496. Epub 2009 Oct 20. Erratum in: Cancer Res. 2009 Dec 1;69(23):9156.

8.

Effect of anti-fibrinolytic therapy on experimental melanoma metastasis.

Kirstein JM, Graham KC, Mackenzie LT, Johnston DE, Martin LJ, Tuck AB, MacDonald IC, Chambers AF.

Clin Exp Metastasis. 2009;26(2):121-31. doi: 10.1007/s10585-008-9221-z. Epub 2008 Dec 12.

PMID:
19082867
9.

Chapter 9. Intravital videomicroscopy in angiogenesis research.

MacDonald IC, Chambers AF.

Methods Enzymol. 2008;444:201-30. doi: 10.1016/S0076-6879(08)02809-7.

PMID:
19007666
10.

Contrast-enhanced microcomputed tomography using intraperitoneal contrast injection for the assessment of tumor-burden in liver metastasis models.

Graham KC, Detombe SA, MacKenzie LT, Holdsworth DW, MacDonald IC, Chambers AF, Drangova M.

Invest Radiol. 2008 Jul;43(7):488-95. doi: 10.1097/RLI.0b013e318172f5b5.

PMID:
18580331
11.

BRMS1 suppresses breast cancer metastasis in multiple experimental models of metastasis by reducing solitary cell survival and inhibiting growth initiation.

Hedley BD, Vaidya KS, Phadke P, MacKenzie L, Dales DW, Postenka CO, MacDonald IC, Chambers AF.

Clin Exp Metastasis. 2008;25(7):727-40. doi: 10.1007/s10585-008-9184-0. Epub 2008 Jun 10.

PMID:
18543067
12.

Downregulation of osteopontin contributes to metastasis suppression by breast cancer metastasis suppressor 1.

Hedley BD, Welch DR, Allan AL, Al-Katib W, Dales DW, Postenka CO, Casey G, Macdonald IC, Chambers AF.

Int J Cancer. 2008 Aug 1;123(3):526-34. doi: 10.1002/ijc.23542.

13.

Noninvasive quantification of tumor volume in preclinical liver metastasis models using contrast-enhanced x-ray computed tomography.

Graham KC, Ford NL, MacKenzie LT, Postenka CO, Groom AC, MacDonald IC, Holdsworth DW, Drangova M, Chambers AF.

Invest Radiol. 2008 Feb;43(2):92-9. doi: 10.1097/RLI.0b013e31815603d7.

PMID:
18197061
14.

A new breast cancer model for lymphatic metastasis.

Lizardo MM, Macdonald IC, Tuck AB, Chambers AF.

Cancer Treat Res. 2007;135:157-65. Review. No abstract available.

PMID:
17953414
15.

In vivo MRI of cancer cell fate at the single-cell level in a mouse model of breast cancer metastasis to the brain.

Heyn C, Ronald JA, Ramadan SS, Snir JA, Barry AM, MacKenzie LT, Mikulis DJ, Palmieri D, Bronder JL, Steeg PS, Yoneda T, MacDonald IC, Chambers AF, Rutt BK, Foster PJ.

Magn Reson Med. 2006 Nov;56(5):1001-10.

16.

Breast cancer metastasis progression as revealed by intravital videomicroscopy.

MacDonald IC, Chambers AF.

Expert Rev Anticancer Ther. 2006 Sep;6(9):1271-9. Review.

PMID:
17020460
17.

Molecular mechanisms of metastasis.

Hoon DS, Kitago M, Kim J, Mori T, Piris A, Szyfelbein K, Mihm MC Jr, Nathanson SD, Padera TP, Chambers AF, Vantyghem SA, MacDonald IC, Shivers SC, Alsarraj M, Reintgen DS, Passlick B, Sienel W, Pantel K.

Cancer Metastasis Rev. 2006 Jun;25(2):203-20. Review.

PMID:
16770533
18.

Volume measurement variability in three-dimensional high-frequency ultrasound images of murine liver metastases.

Wirtzfeld LA, Graham KC, Groom AC, Macdonald IC, Chambers AF, Fenster A, Lacefield JC.

Phys Med Biol. 2006 May 21;51(10):2367-81. Epub 2006 Apr 26.

PMID:
16675858
19.
20.

In vivo magnetic resonance imaging of single cells in mouse brain with optical validation.

Heyn C, Ronald JA, Mackenzie LT, MacDonald IC, Chambers AF, Rutt BK, Foster PJ.

Magn Reson Med. 2006 Jan;55(1):23-9.

21.

Three-dimensional high-frequency ultrasound imaging for longitudinal evaluation of liver metastases in preclinical models.

Graham KC, Wirtzfeld LA, MacKenzie LT, Postenka CO, Groom AC, MacDonald IC, Fenster A, Lacefield JC, Chambers AF.

Cancer Res. 2005 Jun 15;65(12):5231-7.

22.
23.

Mapping of the functional microcirculation in vital organs using contrast-enhanced in vivo video microscopy.

Varghese HJ, MacKenzie LT, Groom AC, Ellis CG, Chambers AF, MacDonald IC.

Am J Physiol Heart Circ Physiol. 2005 Jan;288(1):H185-93. Epub 2004 Sep 23.

24.

Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases.

Naumov GN, Townson JL, MacDonald IC, Wilson SM, Bramwell VH, Groom AC, Chambers AF.

Breast Cancer Res Treat. 2003 Dec;82(3):199-206.

PMID:
14703067
25.

Inhibition of angiogenesis in liver metastases by carboxyamidotriazole (CAI).

Luzzi KJ, Varghese HJ, MacDonald IC, Schmidt EE, Kohn EC, Morris VL, Marshall KE, Chambers AF, Groom AC.

Angiogenesis. 1998;2(4):373-9.

PMID:
14517457
26.

Cancer spread and micrometastasis development: quantitative approaches for in vivo models.

MacDonald IC, Groom AC, Chambers AF.

Bioessays. 2002 Oct;24(10):885-93. Review.

PMID:
12325121
27.

Dissemination and growth of cancer cells in metastatic sites.

Chambers AF, Groom AC, MacDonald IC.

Nat Rev Cancer. 2002 Aug;2(8):563-72. Review.

PMID:
12154349
28.

Persistence of solitary mammary carcinoma cells in a secondary site: a possible contributor to dormancy.

Naumov GN, MacDonald IC, Weinmeister PM, Kerkvliet N, Nadkarni KV, Wilson SM, Morris VL, Groom AC, Chambers AF.

Cancer Res. 2002 Apr 1;62(7):2162-8.

29.

Activated ras regulates the proliferation/apoptosis balance and early survival of developing micrometastases.

Varghese HJ, Davidson MT, MacDonald IC, Wilson SM, Nadkarni KV, Groom AC, Chambers AF.

Cancer Res. 2002 Feb 1;62(3):887-91.

30.

Solitary cancer cells as a possible source of tumour dormancy?

Naumov GN, MacDonald IC, Chambers AF, Groom AC.

Semin Cancer Biol. 2001 Aug;11(4):271-6. Review.

PMID:
11513562
31.

Critical steps in hematogenous metastasis: an overview.

Chambers AF, Naumov GN, Varghese HJ, Nadkarni KV, MacDonald IC, Groom AC.

Surg Oncol Clin N Am. 2001 Apr;10(2):243-55, vii. Review.

PMID:
11382585
32.

Clinical targets for anti-metastasis therapy.

Chambers AF, MacDonald IC, Schmidt EE, Morris VL, Groom AC.

Adv Cancer Res. 2000;79:91-121. Review.

PMID:
10818678
33.

Temporal progression of metastasis in lung: cell survival, dormancy, and location dependence of metastatic inefficiency.

Cameron MD, Schmidt EE, Kerkvliet N, Nadkarni KV, Morris VL, Groom AC, Chambers AF, MacDonald IC.

Cancer Res. 2000 May 1;60(9):2541-6.

34.

Tumour metastasis to the liver, and the roles of proteinases and adhesion molecules: new concepts from in vivo videomicroscopy.

Groom AC, MacDonald IC, Schmidt EE, Morris VL, Chambers AF.

Can J Gastroenterol. 1999 Nov;13(9):733-43. Review.

PMID:
10633826
35.

The matrix metalloproteinase inhibitor batimastat inhibits angiogenesis in liver metastases of B16F1 melanoma cells.

Wylie S, MacDonald IC, Varghese HJ, Schmidt EE, Morris VL, Groom AC, Chambers AF.

Clin Exp Metastasis. 1999 Mar;17(2):111-7.

PMID:
10411102
36.

Preclinical assessment of anti-cancer therapeutic strategies using in vivo videomicroscopy.

Chambers AF, MacDonald IC, Schmidt EE, Morris VL, Groom AC.

Cancer Metastasis Rev. 1998-1999;17(3):263-9. Review.

PMID:
10352879
37.

Cellular expression of green fluorescent protein, coupled with high-resolution in vivo videomicroscopy, to monitor steps in tumor metastasis.

Naumov GN, Wilson SM, MacDonald IC, Schmidt EE, Morris VL, Groom AC, Hoffman RM, Chambers AF.

J Cell Sci. 1999 Jun;112 ( Pt 12):1835-42.

38.

Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases.

Luzzi KJ, MacDonald IC, Schmidt EE, Kerkvliet N, Morris VL, Chambers AF, Groom AC.

Am J Pathol. 1998 Sep;153(3):865-73.

39.

Morphologic sites for regulating blood flow in the exocrine pancreas.

Aharinejad S, MacDonald IC, Miksovsky A.

Microsc Res Tech. 1997 Jun 1-15;37(5-6):434-49.

PMID:
9220422
40.

Sequential steps in hematogenous metastasis of cancer cells studied by in vivo videomicroscopy.

Morris VL, Schmidt EE, MacDonald IC, Groom AC, Chambers AF.

Invasion Metastasis. 1997;17(6):281-96. Review.

PMID:
9949288
41.

Independence of metastatic ability and extravasation: metastatic ras-transformed and control fibroblasts extravasate equally well.

Koop S, Schmidt EE, MacDonald IC, Morris VL, Khokha R, Grattan M, Leone J, Chambers AF, Groom AC.

Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):11080-4.

42.

Integrin VLA-2 (alpha2beta1) function in postextravasation movement of human rhabdomyosarcoma RD cells in the liver.

Hangan D, Uniyal S, Morris VL, MacDonald IC, von Ballestrem C, Chau T, Schmidt EE, Chambers AF, Groom AC, Chan BM.

Cancer Res. 1996 Jul 1;56(13):3142-9.

43.

Steps in tumor metastasis: new concepts from intravital videomicroscopy.

Chambers AF, MacDonald IC, Schmidt EE, Koop S, Morris VL, Khokha R, Groom AC.

Cancer Metastasis Rev. 1995 Dec;14(4):279-301. Review.

PMID:
8821091
44.

Effects of the disintegrin eristostatin on individual steps of hematogenous metastasis.

Morris VL, Schmidt EE, Koop S, MacDonald IC, Grattan M, Khokha R, McLane MA, Niewiarowski S, Chambers AF, Groom AC.

Exp Cell Res. 1995 Aug;219(2):571-8.

PMID:
7641809
45.

Fate of melanoma cells entering the microcirculation: over 80% survive and extravasate.

Koop S, MacDonald IC, Luzzi K, Schmidt EE, Morris VL, Grattan M, Khokha R, Chambers AF, Groom AC.

Cancer Res. 1995 Jun 15;55(12):2520-3.

46.

Luminal constrictions due to endothelial cells in capillaries of mouse exocrine pancreas.

MacDonald IC, Aharinejad S, Schmidt EE, Groom AC.

Microvasc Res. 1995 Jan;49(1):64-77.

PMID:
7746164
47.

Mammary carcinoma cell lines of high and low metastatic potential differ not in extravasation but in subsequent migration and growth.

Morris VL, Koop S, MacDonald IC, Schmidt EE, Grattan M, Percy D, Chambers AF, Groom AC.

Clin Exp Metastasis. 1994 Nov;12(6):357-67.

PMID:
7923988
48.

Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth.

Koop S, Khokha R, Schmidt EE, MacDonald IC, Morris VL, Chambers AF, Groom AC.

Cancer Res. 1994 Sep 1;54(17):4791-7.

49.

New aspects of microvascular corrosion casting: a scanning, transmission electron, and high-resolution intravital video microscopic study.

Aharinejad S, MacDonald IC, MacKay CE, Mason-Savas A.

Microsc Res Tech. 1993 Dec 15;26(6):473-88.

PMID:
8305725
50.

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