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Items: 1 to 50 of 56

1.

Small-molecule induction of Aβ-42 peptide production in human cerebral organoids to model Alzheimer's disease associated phenotypes.

Pavoni S, Jarray R, Nassor F, Guyot AC, Cottin S, Rontard J, Mikol J, Mabondzo A, Deslys JP, Yates F.

PLoS One. 2018 Dec 17;13(12):e0209150. doi: 10.1371/journal.pone.0209150. eCollection 2018.

2.

Antibodies targeting human endothelin-1 receptors reveal different conformational states in cancer cells.

Herbet A, Costa N, Leventoux N, Mabondzo A, Couraud JY, Borrull A, Hugnot JP, Boquet D.

Physiol Res. 2018 Jun 27;67(Supplementum 1):S257-S264.

3.

PEG-PGA enveloped octaarginine-peptide nanocomplexes: An oral peptide delivery strategy.

Niu Z, Samaridou E, Jaumain E, Coëne J, Ullio G, Shrestha N, Garcia J, Durán-Lobato M, Tovar S, Santander-Ortega MJ, Lozano MV, Arroyo-Jimenez MM, Ramos-Membrive R, Peñuelas I, Mabondzo A, Préat V, Teixidó M, Giralt E, Alonso MJ.

J Control Release. 2018 Apr 28;276:125-139. doi: 10.1016/j.jconrel.2018.03.004. Epub 2018 Mar 6.

PMID:
29518466
4.

Cognitive deficits and increases in creatine precursors in a brain-specific knockout of the creatine transporter gene Slc6a8.

Udobi KC, Kokenge AN, Hautman ER, Ullio G, Coene J, Williams MT, Vorhees CV, Mabondzo A, Skelton MR.

Genes Brain Behav. 2018 Jul;17(6):e12461. doi: 10.1111/gbb.12461. Epub 2018 Feb 20.

PMID:
29384270
5.

Brain Inflammation, Blood Brain Barrier dysfunction and Neuronal Synaptophysin Decrease after Inhalation Exposure to Titanium Dioxide Nano-aerosol in Aging Rats.

Disdier C, Chalansonnet M, Gagnaire F, Gaté L, Cosnier F, Devoy J, Saba W, Lund AK, Brun E, Mabondzo A.

Sci Rep. 2017 Sep 22;7(1):12196. doi: 10.1038/s41598-017-12404-5.

6.

Rational design of polyarginine nanocapsules intended to help peptides overcoming intestinal barriers.

Niu Z, Tedesco E, Benetti F, Mabondzo A, Montagner IM, Marigo I, Gonzalez-Touceda D, Tovar S, Diéguez C, Santander-Ortega MJ, Alonso MJ.

J Control Release. 2017 Oct 10;263:4-17. doi: 10.1016/j.jconrel.2017.02.024. Epub 2017 Feb 21.

7.

Biopersistence and translocation to extrapulmonary organs of titanium dioxide nanoparticles after subacute inhalation exposure to aerosol in adult and elderly rats.

Gaté L, Disdier C, Cosnier F, Gagnaire F, Devoy J, Saba W, Brun E, Chalansonnet M, Mabondzo A.

Toxicol Lett. 2017 Jan 4;265:61-69. doi: 10.1016/j.toxlet.2016.11.009. Epub 2016 Nov 16.

PMID:
27865850
8.

Specific Triazine Herbicides Induce Amyloid-β42 Production.

Portelius E, Durieu E, Bodin M, Cam M, Pannee J, Leuxe C, Mabondzo A, Oumata N, Galons H, Lee JY, Chang YT, Stϋber K, Koch P, Fontaine G, Potier MC, Manousopoulou A, Garbis SD, Covaci A, Van Dam D, De Deyn P, Karg F, Flajolet M, Omori C, Hata S, Suzuki T, Blennow K, Zetterberg H, Meijer L.

J Alzheimers Dis. 2016 Oct 18;54(4):1593-1605.

PMID:
27589520
9.

Ontogeny of ABC and SLC transporters in the microvessels of developing rat brain.

Soares RV, Do TM, Mabondzo A, Pons G, Chhun S.

Fundam Clin Pharmacol. 2016 Apr;30(2):107-16. doi: 10.1111/fcp.12175. Epub 2016 Feb 4.

PMID:
26662930
10.

Tissue biodistribution of intravenously administrated titanium dioxide nanoparticles revealed blood-brain barrier clearance and brain inflammation in rat.

Disdier C, Devoy J, Cosnefroy A, Chalansonnet M, Herlin-Boime N, Brun E, Lund A, Mabondzo A.

Part Fibre Toxicol. 2015 Sep 4;12:27. doi: 10.1186/s12989-015-0102-8.

11.

Titanium dioxide nanoparticle impact and translocation through ex vivo, in vivo and in vitro gut epithelia.

Brun E, Barreau F, Veronesi G, Fayard B, Sorieul S, Chanéac C, Carapito C, Rabilloud T, Mabondzo A, Herlin-Boime N, Carrière M.

Part Fibre Toxicol. 2014 Mar 25;11:13. doi: 10.1186/1743-8977-11-13.

12.

Dodecyl creatine ester and lipid nanocapsule: a double strategy for the treatment of creatine transporter deficiency.

Trotier-Faurion A, Passirani C, Béjaud J, Dézard S, Valayannopoulos V, Taran F, de Lonlay P, Benoit JP, Mabondzo A.

Nanomedicine (Lond). 2015 Jan;10(2):185-91. doi: 10.2217/nnm.13.205. Epub 2014 Feb 21.

PMID:
24559037
13.

Exposure to vehicle emissions results in altered blood brain barrier permeability and expression of matrix metalloproteinases and tight junction proteins in mice.

Oppenheim HA, Lucero J, Guyot AC, Herbert LM, McDonald JD, Mabondzo A, Lund AK.

Part Fibre Toxicol. 2013 Dec 17;10:62. doi: 10.1186/1743-8977-10-62.

14.

Synthesis and biological evaluation of new creatine fatty esters revealed dodecyl creatine ester as a promising drug candidate for the treatment of the creatine transporter deficiency.

Trotier-Faurion A, Dézard S, Taran F, Valayannopoulos V, de Lonlay P, Mabondzo A.

J Med Chem. 2013 Jun 27;56(12):5173-81. doi: 10.1021/jm400545n. Epub 2013 Jun 7.

PMID:
23697594
15.
16.
17.

In vitro evidence of dysregulation of blood-brain barrier function after acute and repeated/long-term exposure to TiO(2) nanoparticles.

Brun E, Carrière M, Mabondzo A.

Biomaterials. 2012 Jan;33(3):886-96. doi: 10.1016/j.biomaterials.2011.10.025. Epub 2011 Oct 24.

PMID:
22027597
18.

In vitro primary human and animal cell-based blood-brain barrier models as a screening tool in drug discovery.

Lacombe O, Videau O, Chevillon D, Guyot AC, Contreras C, Blondel S, Nicolas L, Ghettas A, Bénech H, Thevenot E, Pruvost A, Bolze S, Krzaczkowski L, Prévost C, Mabondzo A.

Mol Pharm. 2011 Jun 6;8(3):651-63. doi: 10.1021/mp1004614. Epub 2011 Apr 15.

PMID:
21438632
19.

Drug bioanalysis and biomarker discovery at the Commissariat à l'énergie atomique et aux énergies alternatives.

Ezan E, Becher F, Benech H, Fenaille F, Junot C, Mabondzo A, Pruvost A.

Bioanalysis. 2010 Apr;2(4):713-7. doi: 10.4155/bio.10.16. No abstract available.

20.

Validation of in vitro cell-based human blood-brain barrier model using clinical positron emission tomography radioligands to predict in vivo human brain penetration.

Mabondzo A, Bottlaender M, Guyot AC, Tsaouin K, Deverre JR, Balimane PV.

Mol Pharm. 2010 Oct 4;7(5):1805-15. doi: 10.1021/mp1002366. Epub 2010 Sep 15.

PMID:
20795735
21.

In vivo effects of zearalenone on the expression of proteins involved in the detoxification of rat xenobiotics.

Duca RC, Mabondzo A, Bravin F, Delaforge M.

Environ Toxicol. 2012 Feb;27(2):98-108. doi: 10.1002/tox.20617. Epub 2010 Jul 6.

PMID:
20607812
22.

ADDME--Avoiding Drug Development Mistakes Early: central nervous system drug discovery perspective.

Tsaioun K, Bottlaender M, Mabondzo A; Alzheimer's Drug Discovery Foundation.

BMC Neurol. 2009 Jun 12;9 Suppl 1:S1. doi: 10.1186/1471-2377-9-S1-S1. Review.

23.

Combination of tenofovir and emtricitabine plus efavirenz: in vitro modulation of ABC transporter and intracellular drug accumulation.

Bousquet L, Pruvost A, Guyot AC, Farinotti R, Mabondzo A.

Antimicrob Agents Chemother. 2009 Mar;53(3):896-902. doi: 10.1128/AAC.00733-08. Epub 2008 Dec 15.

24.

Comparison of ABC transporter modulation by atazanavir in lymphocytes and human brain endothelial cells: ABC transporters are involved in the atazanavir-limited passage across an in vitro human model of the blood-brain barrier.

Bousquet L, Roucairol C, Hembury A, Nevers MC, Creminon C, Farinotti R, Mabondzo A.

AIDS Res Hum Retroviruses. 2008 Sep;24(9):1147-54. doi: 10.1089/aid.2007.0022.

PMID:
18729774
25.

Emtricitabine: Inhibitor and substrate of multidrug resistance associated protein.

Bousquet L, Pruvost A, Didier N, Farinotti R, Mabondzo A.

Eur J Pharm Sci. 2008 Nov 15;35(4):247-56. doi: 10.1016/j.ejps.2008.06.017. Epub 2008 Jul 18.

PMID:
18692133
26.

Endothelial cell-derived bone morphogenetic proteins control proliferation of neural stem/progenitor cells.

Mathieu C, Sii-Felice K, Fouchet P, Etienne O, Haton C, Mabondzo A, Boussin FD, Mouthon MA.

Mol Cell Neurosci. 2008 Aug;38(4):569-77. doi: 10.1016/j.mcn.2008.05.005. Epub 2008 May 20.

PMID:
18583149
27.

Endothelin-1 reduces p-glycoprotein transport activity in an in vitro model of human adult blood-brain barrier.

Hembury A, Mabondzo A.

Cell Mol Neurobiol. 2008 Nov;28(7):915-21. doi: 10.1007/s10571-008-9277-y. Epub 2008 Apr 1.

PMID:
18379872
28.

Evaluation of drug penetration into the brain: a double study by in vivo imaging with positron emission tomography and using an in vitro model of the human blood-brain barrier.

Josserand V, Pélerin H, de Bruin B, Jego B, Kuhnast B, Hinnen F, Ducongé F, Boisgard R, Beuvon F, Chassoux F, Daumas-Duport C, Ezan E, Dollé F, Mabondzo A, Tavitian B.

J Pharmacol Exp Ther. 2006 Jan;316(1):79-86. Epub 2005 Oct 6.

PMID:
16210395
29.

Increased expression of MDR1 mRNAs and P-glycoprotein in placentas from HIV-1 infected women.

Camus M, Deloménie C, Didier N, Faye A, Gil S, Dauge MC, Mabondzo A, Farinotti R.

Placenta. 2006 Jun-Jul;27(6-7):699-706. Epub 2005 Sep 12.

PMID:
16165208
30.

First Dominique Dormont International Conference on "Host-pathogen interactions in chronic infections - viral and host determinants of HCV, HCMV, and HIV infections".

Menu E, Müller-Trutwin MC, Pancino G, Saez-Cirion A, Bain C, Inchauspé G, Gras GS, Mabondzo AM, Samri A, Boutboul F, Le Grand R.

Retrovirology. 2005 Apr 6;2:24.

32.

In vitro models for the blood-brain barrier.

Garberg P, Ball M, Borg N, Cecchelli R, Fenart L, Hurst RD, Lindmark T, Mabondzo A, Nilsson JE, Raub TJ, Stanimirovic D, Terasaki T, Oberg JO, Osterberg T.

Toxicol In Vitro. 2005 Apr;19(3):299-334.

PMID:
15713540
33.

ATP binding cassette multidrug transporters limit the anti-HIV activity of zidovudine and indinavir in infected human macrophages.

Jorajuria S, Dereuddre-Bosquet N, Becher F, Martin S, Porcheray F, Garrigues A, Mabondzo A, Benech H, Grassi J, Orlowski S, Dormont D, Clayette P.

Antivir Ther. 2004 Aug;9(4):519-28.

PMID:
15456083
34.
35.

Influence of tumor necrosis factor-alpha on the expression and function of P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT.

Théron D, Barraud de Lagerie S, Tardivel S, Pélerin H, Demeuse P, Mercier C, Mabondzo A, Farinotti R, Lacour B, Roux F, Gimenez F.

Biochem Pharmacol. 2003 Aug 15;66(4):579-87.

PMID:
12906922
36.
37.

HIV-1-induced production of endothelin-1 in an in vitro model of the human blood-brain barrier.

Didier N, Banks WA, Créminon C, Dereuddre-Bosquet N, Mabondzo A.

Neuroreport. 2002 Jul 2;13(9):1179-83.

PMID:
12151765
38.

A co-culture-based model of human blood-brain barrier: application to active transport of indinavir and in vivo-in vitro correlation.

Megard I, Garrigues A, Orlowski S, Jorajuria S, Clayette P, Ezan E, Mabondzo A.

Brain Res. 2002 Feb 15;927(2):153-67.

PMID:
11821009
39.

Lack of correlation between vertical transmission of HIV-1 and maternal antibody titers against autologous virus in human monocyte-derived macrophages.

Mabondzo A, Narwa R, Roques P, Gras GS, Hervé F, Parnet-Mathieu F, Lasfargues G, Courpotin C, Dormont D.

J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Jan 1;17(1):92-4. No abstract available.

PMID:
9436766
41.

Anti-HIV potential of a new interferon, interferon-tau (trophoblastin).

Dereuddre-Bosquet N, Clayette P, Martin M, Mabondzo A, Frétier P, Gras G, Martal J, Dormont D.

J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Mar 1;11(3):241-6.

PMID:
8603260
42.

Inhibition of human immunodeficiency virus infection by heparin derivatives.

Clayette P, Moczar E, Mabondzo A, Martin M, Toutain B, Marcé D, Dormont D.

AIDS Res Hum Retroviruses. 1996 Jan 1;12(1):63-9.

PMID:
8825620
43.

Functional consequences of macrophage infection by human immunodeficiency virus: bispecific antibody targeting of HIV-1-infected cells to Fc gamma RI expressing effector cells.

Mabondzo A, Le Naour R, Le Grand R, Vaslin B, Benveniste O, Cheret A, Raoul H, Romet-Lemonne JL, Dormont D.

J Hematother. 1995 Dec;4(6):579-85.

PMID:
8846019
44.

Clearance of HIV infection in 12 perinatally infected children: clinical, virological and immunological data.

Roques PA, Gras G, Parnet-Mathieu F, Mabondzo AM, Dollfus C, Narwa R, Marcé D, Tranchot-Diallo J, Hervé F, Lasfargues G, et al.

AIDS. 1995 Dec;9(12):F19-26.

PMID:
8605047
45.

Relationships between humoral factors in HIV-1-infected mothers and the occurrence of HIV infection in their infants.

Mabondzo A, Rouvier P, Raoul H, Le Naour R, Courpotin C, Hervé F, Parnet-Mathieu F, Lasfargues G, Dormont D.

Clin Exp Immunol. 1995 Dec;102(3):476-80.

46.

Modulations of 92kDa gelatinase B and its inhibitors are associated with HIV-1 infection in human macrophage cultures.

Chapel C, Camara V, Clayette P, Salvat S, Mabondzo A, Leblond V, Marcé D, Lafuma C, Dormont D.

Biochem Biophys Res Commun. 1994 Nov 15;204(3):1272-8.

PMID:
7980605
47.

Antibody-dependent cellular cytotoxicity and neutralization of human immunodeficiency virus type 1 by high affinity cross-linking of gp41 to human macrophage Fc IgG receptor using bispecific antibody.

Mabondzo A, Boussin F, Raoul H, Le Naour R, Gras G, Vaslin B, Bartholeyns J, Romet-Lemonne JL, Dormont D.

J Gen Virol. 1994 Jun;75 ( Pt 6):1451-6.

PMID:
8207409
48.
49.
50.

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