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Items: 1 to 50 of 101

1.

A Compact Device for the Integrated Filtration, Drying, and Mechanical Processing of Active Pharmaceutical Ingredients.

Capellades G, Neurohr C, Azad M, Brancazio D, Rapp K, Hammersmith G, Myerson AS.

J Pharm Sci. 2020 Mar;109(3):1365-1372. doi: 10.1016/j.xphs.2019.12.011. Epub 2019 Dec 20.

PMID:
31866299
2.

On-Demand Manufacturing of Direct Compressible Tablets: Can Formulation Be Simplified?

Azad MA, Osorio JG, Wang A, Klee DM, Eccles ME, Grela E, Sloan R, Hammersmith G, Rapp K, Brancazio D, Myerson AS.

Pharm Res. 2019 Oct 24;36(12):167. doi: 10.1007/s11095-019-2716-2.

PMID:
31650274
3.

Solubility Studies of Cyclosporine Using Ionic Liquids.

Berton P, Mishra MK, Choudhary H, Myerson AS, Rogers RD.

ACS Omega. 2019 May 1;4(5):7938-7943. doi: 10.1021/acsomega.9b00603. eCollection 2019 May 31.

4.

General Method for the Identification of Crystal Faces Using Raman Spectroscopy Combined with Machine Learning and Application to the Epitaxial Growth of Acetaminophen.

Wijethunga TK, Stojaković J, Bellucci MA, Chen X, Myerson AS, Trout BL.

Langmuir. 2018 Aug 21;34(33):9836-9846. doi: 10.1021/acs.langmuir.8b01791. Epub 2018 Aug 9.

PMID:
30053784
5.

Exploring the role of ionic liquids to tune the polymorphic outcome of organic compounds.

Zeng Q, Mukherjee A, Müller P, Rogers RD, Myerson AS.

Chem Sci. 2017 Dec 22;9(6):1510-1520. doi: 10.1039/c7sc04353h. eCollection 2018 Feb 14.

6.

Ionic liquids in cross-coupling reactions: "liquid" solutions to a "solid" precipitation problem.

Choudhary H, Berton P, Gurau G, Myerson AS, Rogers RD.

Chem Commun (Camb). 2018 Feb 20;54(16):2056-2059. doi: 10.1039/c7cc09635f.

PMID:
29417101
7.

Advanced Continuous Flow Platform for On-Demand Pharmaceutical Manufacturing.

Zhang P, Weeranoppanant N, Thomas DA, Tahara K, Stelzer T, Russell MG, O'Mahony M, Myerson AS, Lin H, Kelly LP, Jensen KF, Jamison TF, Dai C, Cui Y, Briggs N, Beingessner RL, Adamo A.

Chemistry. 2018 Feb 21;24(11):2776-2784. doi: 10.1002/chem.201706004. Epub 2018 Jan 31.

PMID:
29385292
8.

A compact, portable, re-configurable, and automated system for on-demand pharmaceutical tablet manufacturing.

Azad MA, Osorio JG, Brancazio D, Hammersmith G, Klee DM, Rapp K, Myerson A.

Int J Pharm. 2018 Mar 25;539(1-2):157-164. doi: 10.1016/j.ijpharm.2018.01.027. Epub 2018 Jan 31.

PMID:
29366938
9.

Demonstration of pharmaceutical tablet coating process by injection molding technology.

Puri V, Brancazio D, Harinath E, Martinez AR, Desai PM, Jensen KD, Chun JH, Braatz RD, Myerson AS, Trout BL.

Int J Pharm. 2018 Jan 15;535(1-2):106-112. doi: 10.1016/j.ijpharm.2017.10.062. Epub 2017 Nov 4.

PMID:
29113803
10.

Separate mechanisms of ion oligomerization tune the physicochemical properties of n-butylammonium acetate: cation-base clusters vs. anion-acid dimers.

Berton P, Kelley SP, Wang H, Myerson AS, Rogers RD.

Phys Chem Chem Phys. 2017 Sep 27;19(37):25544-25554. doi: 10.1039/c7cp04078d.

PMID:
28901353
11.

Integrated hot-melt extrusion - injection molding continuous tablet manufacturing platform: Effects of critical process parameters and formulation attributes on product robustness and dimensional stability.

Desai PM, Hogan RC, Brancazio D, Puri V, Jensen KD, Chun JH, Myerson AS, Trout BL.

Int J Pharm. 2017 Oct 5;531(1):332-342. doi: 10.1016/j.ijpharm.2017.08.097. Epub 2017 Aug 24.

PMID:
28844899
12.

Development of Maltodextrin-Based Immediate-Release Tablets Using an Integrated Twin-Screw Hot-Melt Extrusion and Injection-Molding Continuous Manufacturing Process.

Puri V, Brancazio D, Desai PM, Jensen KD, Chun JH, Myerson AS, Trout BL.

J Pharm Sci. 2017 Nov;106(11):3328-3336. doi: 10.1016/j.xphs.2017.06.020. Epub 2017 Jul 4.

PMID:
28684263
13.

The A Priori Design and Selection of Ionic Liquids as Solvents for Active Pharmaceutical Ingredients.

Kunov-Kruse AJ, Weber CC, Rogers RD, Myerson AS.

Chemistry. 2017 Apr 24;23(23):5498-5508. doi: 10.1002/chem.201605704. Epub 2017 Apr 5.

PMID:
28244156
14.

Reversible control of solubility using functionalized nanoparticles.

Kulkarni SA, Myerson AS.

Chem Commun (Camb). 2017 Jan 24;53(8):1429-1432. doi: 10.1039/c6cc09390f.

PMID:
28079205
15.

Core-Shell Composite Hydrogels for Controlled Nanocrystal Formation and Release of Hydrophobic Active Pharmaceutical Ingredients.

Badruddoza AZ, Godfrin PD, Myerson AS, Trout BL, Doyle PS.

Adv Healthc Mater. 2016 Aug;5(15):1960-8. doi: 10.1002/adhm.201600266. Epub 2016 Jun 1.

PMID:
27249402
16.

On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system.

Adamo A, Beingessner RL, Behnam M, Chen J, Jamison TF, Jensen KF, Monbaliu JC, Myerson AS, Revalor EM, Snead DR, Stelzer T, Weeranoppanant N, Wong SY, Zhang P.

Science. 2016 Apr 1;352(6281):61-7. doi: 10.1126/science.aaf1337.

17.

Confined crystallization of fenofibrate in nanoporous silica.

Dwyer LM, Michaelis VK, O'Mahony M, Griffin RG, Myerson AS.

CrystEngComm. 2015 Nov 7;17(41):7922-7929. Epub 2015 Sep 21.

18.

On the connection between nonmonotonic taste behavior and molecular conformation in solution: The case of rebaudioside-A.

Chopade PD, Sarma B, Santiso EE, Simpson J, Fry JC, Yurttas N, Biermann KL, Chen J, Trout BL, Myerson AS.

J Chem Phys. 2015 Dec 28;143(24):244301. doi: 10.1063/1.4937946.

PMID:
26723665
19.

Understanding and Analyzing Freezing-Point Transitions of Confined Fluids within Nanopores.

Shimizu S, Agrawal KV, O'Mahony M, Drahushuk LW, Manohar N, Myerson AS, Strano MS.

Langmuir. 2015 Sep 22;31(37):10113-8. doi: 10.1021/acs.langmuir.5b02149. Epub 2015 Sep 9.

PMID:
26332689
20.

Formation of Organic Molecular Nanocrystals under Soft Confinement.

Yang X, Ong TC, Michaelis VK, Heng S, Griffin RG, Myerson AS.

CrystEngComm. 2015 Aug 21;17(31):6044-6052.

21.

Solvent and additive interactions as determinants in the nucleation pathway: general discussion.

Sun CC, Sun W, Price S, Hughes C, Ter Horst J, Veesler S, Lewtas K, Myerson A, Pan H, Coquerel G, van den Ende J, Meekes H, Mazzotti M, Rosbottom I, Taulelle F, Black S, Mackenzie A, Janbon S, Vekilov P, Threlfall T, Turner T, Back K, Cuppen H, Toroz D, Sefcik J, Lovelock J, Hammond R, Candoni N, Simone E, Ward M, Bertran CA, Vetter T, Sear R, De Yoreo J, Davey R, Anwar J, Santiso E, Wu DT, Roberts K, Peters B, Schroeder S, Jones F, Rasmuson A, Cölfen H, Zeglinski J, Salvalaglio M.

Faraday Discuss. 2015;179:383-420. doi: 10.1039/c5fd90038g. Epub 2015 Jun 17. No abstract available.

PMID:
26083497
22.

Nucleation in complex multi-component and multi-phase systems: general discussion.

Price S, Rimez B, Sun W, Peters B, Christenson H, Hughes C, Sun CC, Veesler S, Pan H, Brandel C, Biscans B, Meekes H, Rosbottom I, Roth WJ, Seton L, Taulelle F, Black S, Threlfall T, Vekilov P, Poornachary S, Diemand J, Toroz D, Salvalaglio M, Tipduangta P, Sefcik J, Booth S, Rasmuson A, Janbon S, Ter Horst J, Simone E, Hammond R, Bertran CA, Vetter T, Sear R, De Yoreo J, Harris K, Ristic R, Kavanagh A, Roberts K, Breynaert E, Myerson A, Coquerel G, Wu D, Cölfen H, Cuppen H, Smets M, Wu DT.

Faraday Discuss. 2015;179:503-42. doi: 10.1039/c5fd90039e. Epub 2015 Jun 17. No abstract available.

PMID:
26081969
23.

Time and space resolved methods: general discussion.

Sun W, Booth S, Myerson A, Hughes C, Pan H, Coquerel G, Brandel C, Meekes H, Mazzotti M, Fabian L, Black S, Vekilov P, Back K, Toroz D, Lovelock J, Sefcik J, Rasmuson A, Breynaert E, Sear R, Hammond R, Ward M, Threlfall T, De Yoreo J, Davey R, Ristic R, Lewtas K, Roberts K, Hare A, Gich M, Cölfen H, Likhatskiy M, ter Horst J, Sommerdijk N.

Faraday Discuss. 2015;179:247-67. doi: 10.1039/c5fd90037a. Epub 2015 Jun 16. No abstract available.

PMID:
26077829
24.

Molecular self-assembly and clustering in nucleation processes: general discussion.

Price S, Veesler S, Pan H, Lewtas K, Smets M, Rimez B, Myerson A, Hughes C, Hare A, Zhang F, Meekes H, Mazzotti M, Rosbottom I, Khamar D, van den Ende J, Fabian L, Black S, Taulelle F, Gich M, Vekilov P, Toroz D, Bertran CA, Sefcik J, Schroeder S, Booth S, Rasmuson A, Breynaert E, Simone E, Hammond R, Sear R, de Yoreo J, Davey R, Anwar J, Ristic R, Camacho Corzo DM, Roberts K, Harris K, Colfen H, Turner T.

Faraday Discuss. 2015;179:155-97. doi: 10.1039/c5fd90036k. Epub 2015 Jun 15. No abstract available.

PMID:
26075634
25.

Concluding remarks.

Myerson AS.

Faraday Discuss. 2015;179:543-7. doi: 10.1039/c5fd00042d. Epub 2015 May 18.

PMID:
25985136
26.

Control Systems Engineering in Continuous Pharmaceutical Manufacturing May 20-21, 2014 Continuous Manufacturing Symposium.

Myerson AS, Krumme M, Nasr M, Thomas H, Braatz RD.

J Pharm Sci. 2015 Mar;104(3):832-839. doi: 10.1002/jps.24311. Epub 2016 Jan 8.

PMID:
28756845
27.

Achieving Continuous Manufacturing for Final Dosage Formation: Challenges and How to Meet Them May 20-21 2014 Continuous Manufacturing Symposium.

Byrn S, Futran M, Thomas H, Jayjock E, Maron N, Meyer RF, Myerson AS, Thien MP, Trout BL.

J Pharm Sci. 2015 Mar;104(3):792-802. doi: 10.1002/jps.24247. Epub 2016 Jan 8.

PMID:
28756841
28.

Manipulation of ionic liquid anion-solute-antisolvent interactions for the purification of acetaminophen.

Weber CC, Kunov-Kruse AJ, Rogers RD, Myerson AS.

Chem Commun (Camb). 2015 Mar 11;51(20):4294-7. doi: 10.1039/c5cc00198f.

PMID:
25673089
29.

Ionic fluids containing both strongly and weakly interacting ions of the same charge have unique ionic and chemical environments as a function of ion concentration.

Wang H, Kelley SP, Brantley JW 3rd, Chatel G, Shamshina J, Pereira JF, Debbeti V, Myerson AS, Rogers RD.

Chemphyschem. 2015 Apr 7;16(5):993-1002. doi: 10.1002/cphc.201402894. Epub 2015 Feb 4.

PMID:
25652555
30.

Control systems engineering in continuous pharmaceutical manufacturing. May 20-21, 2014 Continuous Manufacturing Symposium.

Myerson AS, Krumme M, Nasr M, Thomas H, Braatz RD.

J Pharm Sci. 2015 Mar;104(3):832-9. doi: 10.1002/jps.24311. Epub 2014 Dec 26. Review.

PMID:
25546650
31.

Achieving continuous manufacturing for final dosage formation: challenges and how to meet them. May 20-21, 2014 Continuous Manufacturing Symposium.

Byrn S, Futran M, Thomas H, Jayjock E, Maron N, Meyer RF, Myerson AS, Thien MP, Trout BL.

J Pharm Sci. 2015 Mar;104(3):792-802. doi: 10.1002/jps.24247. Epub 2014 Dec 12. Review.

PMID:
25501530
32.

Formation of Organic Molecular Nanocrystals under Rigid Confinement with Analysis by Solid State NMR.

Yang X, Ong TC, Michaelis VK, Heng S, Huang J, Griffin RG, Myerson AS.

CrystEngComm. 2014 Oct 21;16(39):9345-9352.

33.

Self-association during heterogeneous nucleation onto well-defined templates.

Kulkarni SA, Weber CC, Myerson AS, ter Horst JH.

Langmuir. 2014 Oct 21;30(41):12368-75. doi: 10.1021/la5024828. Epub 2014 Oct 8.

34.

Separation and enrichment of enantiopure from racemic compounds using magnetic levitation.

Yang X, Wong SY, Bwambok DK, Atkinson MB, Zhang X, Whitesides GM, Myerson AS.

Chem Commun (Camb). 2014 Jul 18;50(56):7548-51. doi: 10.1039/c4cc02604g.

PMID:
24875274
35.

End-to-end continuous manufacturing of pharmaceuticals: integrated synthesis, purification, and final dosage formation.

Mascia S, Heider PL, Zhang H, Lakerveld R, Benyahia B, Barton PI, Braatz RD, Cooney CL, Evans JM, Jamison TF, Jensen KF, Myerson AS, Trout BL.

Angew Chem Int Ed Engl. 2013 Nov 18;52(47):12359-63. doi: 10.1002/anie.201305429. Epub 2013 Oct 2.

PMID:
24115355
36.

Chemistry. Nucleation from solution.

Myerson AS, Trout BL.

Science. 2013 Aug 23;341(6148):855-6. doi: 10.1126/science.1243022. No abstract available.

PMID:
23970690
37.

Using magnetic levitation to separate mixtures of crystal polymorphs.

Atkinson MB, Bwambok DK, Chen J, Chopade PD, Thuo MM, Mace CR, Mirica KA, Kumar AA, Myerson AS, Whitesides GM.

Angew Chem Int Ed Engl. 2013 Sep 23;52(39):10208-11. doi: 10.1002/anie.201305549. Epub 2013 Aug 12. No abstract available.

PMID:
23939940
38.

Templated nucleation of acetaminophen on spherical excipient agglomerates.

Quon JL, Chadwick K, Wood GP, Sheu I, Brettmann BK, Myerson AS, Trout BL.

Langmuir. 2013 Mar 12;29(10):3292-300. doi: 10.1021/la3041083. Epub 2013 Feb 25.

PMID:
23414233
39.

Electrospun formulations containing crystalline active pharmaceutical ingredients.

Brettmann BK, Cheng K, Myerson AS, Trout BL.

Pharm Res. 2013 Jan;30(1):238-46. doi: 10.1007/s11095-012-0868-4. Epub 2012 Aug 25.

PMID:
22923352
40.

Free surface electrospinning of fibers containing microparticles.

Brettmann BK, Tsang S, Forward KM, Rutledge GC, Myerson AS, Trout BL.

Langmuir. 2012 Jun 26;28(25):9714-21. doi: 10.1021/la301422x. Epub 2012 Jun 6.

PMID:
22621200
41.

Solid-state nuclear magnetic resonance study of the physical stability of electrospun drug and polymer solid solutions.

Brettmann BK, Myerson AS, Trout BL.

J Pharm Sci. 2012 Jun;101(6):2185-93. doi: 10.1002/jps.23107. Epub 2012 Mar 12.

PMID:
22411707
42.

Solid-state NMR characterization of high-loading solid solutions of API and excipients formed by electrospinning.

Brettmann B, Bell E, Myerson A, Trout B.

J Pharm Sci. 2012 Apr;101(4):1538-45. doi: 10.1002/jps.23032. Epub 2011 Dec 27.

PMID:
22213488
43.

Production and characterization of carbamazepine nanocrystals by electrospraying for continuous pharmaceutical manufacturing.

Wang M, Rutledge GC, Myerson AS, Trout BL.

J Pharm Sci. 2012 Mar;101(3):1178-88. doi: 10.1002/jps.23024. Epub 2011 Dec 20.

PMID:
22189503
44.

Gel-induced selective crystallization of polymorphs.

Diao Y, Whaley KE, Helgeson ME, Woldeyes MA, Doyle PS, Myerson AS, Hatton TA, Trout BL.

J Am Chem Soc. 2012 Jan 11;134(1):673-84. doi: 10.1021/ja210006t. Epub 2011 Dec 27.

PMID:
22136445
45.

The role of nanopore shape in surface-induced crystallization.

Diao Y, Harada T, Myerson AS, Hatton TA, Trout BL.

Nat Mater. 2011 Sep 11;10(11):867-71. doi: 10.1038/nmat3117.

PMID:
21909112
46.

Surface design for controlled crystallization: the role of surface chemistry and nanoscale pores in heterogeneous nucleation.

Diao Y, Myerson AS, Hatton TA, Trout BL.

Langmuir. 2011 May 3;27(9):5324-34. doi: 10.1021/la104351k. Epub 2011 Apr 11.

PMID:
21480598
47.

Controlled nucleation from solution using polymer microgels.

Diao Y, Helgeson ME, Myerson AS, Hatton TA, Doyle PS, Trout BL.

J Am Chem Soc. 2011 Mar 23;133(11):3756-9. doi: 10.1021/ja110801g. Epub 2011 Feb 23.

PMID:
21344857
48.

Crystal polymorphism in chemical process development.

Lee AY, Erdemir D, Myerson AS.

Annu Rev Chem Biomol Eng. 2011;2:259-80. doi: 10.1146/annurev-chembioeng-061010-114224. Review.

PMID:
22432619
49.

Chiral self assembled monolayers as resolving auxiliaries in the crystallization of valine.

Singh A, Myerson AS.

J Pharm Sci. 2010 Sep;99(9):3931-40. doi: 10.1002/jps.22237.

PMID:
20533552
50.

Formation of nanosized organic molecular crystals on engineered surfaces.

Kim K, Lee IS, Centrone A, Hatton TA, Myerson AS.

J Am Chem Soc. 2009 Dec 30;131(51):18212-3. doi: 10.1021/ja908055y.

PMID:
19958030

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