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Items: 1 to 50 of 714

1.

Protein kinase A inhibits tumor mutator APOBEC3B through phosphorylation.

Matsumoto T, Shirakawa K, Yokoyama M, Fukuda H, Sarca AD, Koyabu S, Yamazaki H, Kazuma Y, Matsui H, Maruyama W, Nagata K, Tanabe F, Kobayashi M, Shindo K, Morishita R, Sato H, Takaori-Kondo A.

Sci Rep. 2019 Jun 5;9(1):8307. doi: 10.1038/s41598-019-44407-9.

2.

Peptide vaccine for semaphorin3E ameliorates systemic glucose intolerance in mice with dietary obesity.

Yoshida Y, Shimizu I, Hayashi Y, Ikegami R, Suda M, Katsuumi G, Wakasugi T, Nakao M, Nakagami H, Morishita R, Minamino T.

Sci Rep. 2019 Mar 7;9(1):3858. doi: 10.1038/s41598-019-40325-y.

3.

Dysfunctional high density lipoprotein failed to rescue the function of oxidized low density lipoprotein-treated endothelial progenitor cells: a novel index for the prediction of HDL functionality.

Shih CM, Lin FY, Yeh JS, Lin YW, Loh SH, Tsao NW, Nakagami H, Morishita R, Sawamura T, Li CY, Lin CY, Huang CY.

Transl Res. 2019 Mar;205:17-32. doi: 10.1016/j.trsl.2018.09.005. Epub 2018 Oct 9.

PMID:
30720435
4.

NF-κB Decoy Oligodeoxynucleotide-Coated Balloon Catheter for Arteriovenous Fistula in Hemodialysis.

Fukasawa M, Isobe M, Nanto S, Nakamura M, Haruguchi H, Miyake T, Morishita R.

Kidney Int Rep. 2018 Oct 1;4(1):126-138. doi: 10.1016/j.ekir.2018.09.016. eCollection 2019 Jan.

5.

Therapeutic Vaccine Against S100A9 (S100 Calcium-Binding Protein A9) Inhibits Thrombosis Without Increasing the Risk of Bleeding in Ischemic Stroke in Mice.

Kawano T, Shimamura M, Nakagami H, Iso T, Koriyama H, Takeda S, Baba K, Sasaki T, Sakaguchi M, Morishita R, Mochizuki H.

Hypertension. 2018 Dec;72(6):1355-1364. doi: 10.1161/HYPERTENSIONAHA.118.11316.

PMID:
30571223
6.

Development of a novel RANKL-based peptide, microglial healing peptide1-AcN (MHP1-AcN), for treatment of ischemic stroke.

Shimamura M, Nakagami H, Shimizu H, Mukai H, Watanabe R, Okuzono T, Kawano T, Ikeda Y, Hayashi H, Yoshida S, Ju N, Mochizuki H, Morishita R.

Sci Rep. 2018 Dec 11;8(1):17770. doi: 10.1038/s41598-018-35898-z.

7.

Beneficial effect of laughter therapy on physiological and psychological function in elders.

Yoshikawa Y, Ohmaki E, Kawahata H, Maekawa Y, Ogihara T, Morishita R, Aoki M.

Nurs Open. 2018 Jul 18;6(1):93-99. doi: 10.1002/nop2.190. eCollection 2019 Jan.

8.

Rho family GTPases, Rac and Cdc42, control the localization of neonatal dentate granule cells during brain development.

Ito H, Morishita R, Mizuno M, Tabata H, Nagata KI.

Hippocampus. 2019 Jul;29(7):569-578. doi: 10.1002/hipo.23047. Epub 2018 Nov 25.

PMID:
30387892
9.

Recent Advances in Therapeutic Vaccines to Treat Hypertension.

Nakagami H, Morishita R.

Hypertension. 2018 Nov;72(5):1031-1036. doi: 10.1161/HYPERTENSIONAHA.118.11084. Review. No abstract available.

PMID:
30354822
10.

Biochemical and Morphological Characterization of a Neurodevelopmental Disorder-Related Mono-ADP-Ribosylhydrolase, MACRO Domain Containing 2.

Ito H, Morishita R, Mizuno M, Kawamura N, Tabata H, Nagata KI.

Dev Neurosci. 2018;40(3):278-287. doi: 10.1159/000492271. Epub 2018 Sep 18.

PMID:
30227424
11.

Therapeutic Effects of Systemic Administration of the Novel RANKL-Modified Peptide, MHP1, for Ischemic Stroke in Mice.

Shimamura M, Nakagami H, Shimizu H, Wakayama K, Kawano T, Ikeda Y, Hayashi H, Yoshida S, Mochizuki H, Morishita R.

Biomed Res Int. 2018 Jul 30;2018:4637084. doi: 10.1155/2018/4637084. eCollection 2018.

12.

Functions of Rhotekin, an Effector of Rho GTPase, and Its Binding Partners in Mammals.

Ito H, Morishita R, Nagata KI.

Int J Mol Sci. 2018 Jul 20;19(7). pii: E2121. doi: 10.3390/ijms19072121. Review.

13.

De Novo Macrocyclic Peptide Inhibitors of Hepatitis B Virus Cellular Entry.

Passioura T, Watashi K, Fukano K, Shimura S, Saso W, Morishita R, Ogasawara Y, Tanaka Y, Mizokami M, Sureau C, Suga H, Wakita T.

Cell Chem Biol. 2018 Jul 19;25(7):906-915.e5. doi: 10.1016/j.chembiol.2018.04.011. Epub 2018 May 17.

PMID:
29779957
14.

A new strategy to identify hepatitis B virus entry inhibitors by AlphaScreen technology targeting the envelope-receptor interaction.

Saso W, Tsukuda S, Ohashi H, Fukano K, Morishita R, Matsunaga S, Ohki M, Ryo A, Park SY, Suzuki R, Aizaki H, Muramatsu M, Sureau C, Wakita T, Matano T, Watashi K.

Biochem Biophys Res Commun. 2018 Jun 22;501(2):374-379. doi: 10.1016/j.bbrc.2018.04.187. Epub 2018 May 11.

PMID:
29730285
15.

Gene-Therapeutic Strategies Targeting Angiogenesis in Peripheral Artery Disease.

Sanada F, Taniyama Y, Muratsu J, Otsu R, Shimizu H, Rakugi H, Morishita R.

Medicines (Basel). 2018 Mar 30;5(2). pii: E31. doi: 10.3390/medicines5020031. Review.

16.

Source of Chronic Inflammation in Aging.

Sanada F, Taniyama Y, Muratsu J, Otsu R, Shimizu H, Rakugi H, Morishita R.

Front Cardiovasc Med. 2018 Feb 22;5:12. doi: 10.3389/fcvm.2018.00012. eCollection 2018.

17.

Therapeutic Vaccines for Hypertension: a New Option for Clinical Practice.

Nakagami H, Morishita R.

Curr Hypertens Rep. 2018 Mar 19;20(3):22. doi: 10.1007/s11906-018-0820-z. Review.

PMID:
29556794
18.

IGF Binding Protein-5 Induces Cell Senescence.

Sanada F, Taniyama Y, Muratsu J, Otsu R, Shimizu H, Rakugi H, Morishita R.

Front Endocrinol (Lausanne). 2018 Feb 20;9:53. doi: 10.3389/fendo.2018.00053. eCollection 2018. Review.

19.

Periostin blockade overcomes chemoresistance via restricting the expansion of mesenchymal tumor subpopulations in breast cancer.

Nakazawa Y, Taniyama Y, Sanada F, Morishita R, Nakamori S, Morimoto K, Yeung KT, Yang J.

Sci Rep. 2018 Mar 5;8(1):4013. doi: 10.1038/s41598-018-22340-7.

20.

Prevention of Asthma Exacerbation in a Mouse Model by Simultaneous Inhibition of NF-κB and STAT6 Activation Using a Chimeric Decoy Strategy.

Miyake T, Miyake T, Sakaguchi M, Nankai H, Nakazawa T, Morishita R.

Mol Ther Nucleic Acids. 2018 Mar 2;10:159-169. doi: 10.1016/j.omtn.2017.12.005. Epub 2017 Dec 14.

21.

Development of vaccine for dyslipidemia targeted to a proprotein convertase subtilisin/kexin type 9 (PCSK9) epitope in mice.

Kawakami R, Nozato Y, Nakagami H, Ikeda Y, Shimamura M, Yoshida S, Sun J, Kawano T, Takami Y, Noma T, Rakugi H, Minamino T, Morishita R.

PLoS One. 2018 Feb 13;13(2):e0191895. doi: 10.1371/journal.pone.0191895. eCollection 2018.

22.

Chemical array system, a platform to identify novel hepatitis B virus entry inhibitors targeting sodium taurocholate cotransporting polypeptide.

Kaneko M, Futamura Y, Tsukuda S, Kondoh Y, Sekine T, Hirano H, Fukano K, Ohashi H, Saso W, Morishita R, Matsunaga S, Kawai F, Ryo A, Park SY, Suzuki R, Aizaki H, Ohtani N, Sureau C, Wakita T, Osada H, Watashi K.

Sci Rep. 2018 Feb 9;8(1):2769. doi: 10.1038/s41598-018-20987-w.

23.

Local Production of Activated Factor X in Atherosclerotic Plaque Induced Vascular Smooth Muscle Cell Senescence.

Sanada F, Muratsu J, Otsu R, Shimizu H, Koibuchi N, Uchida K, Taniyama Y, Yoshimura S, Rakugi H, Morishita R.

Sci Rep. 2017 Dec 7;7(1):17172. doi: 10.1038/s41598-017-17508-6.

24.

Association between renin-angiotensin-aldosterone system blockade and future osteoporotic fracture risk in hypertensive population: A population-based cohort study in Taiwan.

Chen CI, Yeh JS, Tsao NW, Lin FY, Shih CM, Chiang KH, Kao YT, Fang YA, Tsai LW, Liu WC, Nakagami H, Morishita R, Kuo YJ, Huang CY.

Medicine (Baltimore). 2017 Nov;96(46):e8331. doi: 10.1097/MD.0000000000008331.

25.

Inhibition of Aneurysm Progression by Direct Renin Inhibition in a Rabbit Model.

Miyake T, Miyake T, Shimizu H, Morishita R.

Hypertension. 2017 Dec;70(6):1201-1209. doi: 10.1161/HYPERTENSIONAHA.117.09815. Epub 2017 Oct 23.

PMID:
29061718
26.

Observation by Real-Time NMR and Interpretation of Length- and Location-Dependent Deamination Activity of APOBEC3B.

Wan L, Nagata T, Morishita R, Takaori-Kondo A, Katahira M.

ACS Chem Biol. 2017 Nov 17;12(11):2704-2708. doi: 10.1021/acschembio.7b00662. Epub 2017 Oct 3.

PMID:
28952713
27.

Expression analyses of Phactr1 (phosphatase and actin regulator 1) during mouse brain development.

Ito H, Mizuno M, Noguchi K, Morishita R, Iwamoto I, Hara A, Nagata KI.

Neurosci Res. 2018 Mar;128:50-57. doi: 10.1016/j.neures.2017.08.002. Epub 2017 Aug 10.

PMID:
28803787
28.

Identification and characterization of a centrosomal protein, FOR20 as a novel S100A6 target.

Sakane K, Nishiguchi M, Denda M, Yamagchi F, Magari M, Kanayama N, Morishita R, Tokumitsu H.

Biochem Biophys Res Commun. 2017 Sep 30;491(4):980-985. doi: 10.1016/j.bbrc.2017.07.161. Epub 2017 Jul 29.

PMID:
28765046
29.

Glial fibrillary acidic protein (GFAP) is a novel biomarker for the prediction of autoimmune diabetes.

Pang Z, Kushiyama A, Sun J, Kikuchi T, Yamazaki H, Iwamoto Y, Koriyama H, Yoshida S, Shimamura M, Higuchi M, Kawano T, Takami Y, Rakugi H, Morishita R, Nakagami H.

FASEB J. 2017 Sep;31(9):4053-4063. doi: 10.1096/fj.201700110R. Epub 2017 May 25.

PMID:
28546444
30.

Autism spectrum disorder-associated genes and the development of dentate granule cells.

Ito H, Morishita R, Nagata KI.

Med Mol Morphol. 2017 Sep;50(3):123-129. doi: 10.1007/s00795-017-0161-z. Epub 2017 May 22. Review.

PMID:
28534217
31.

A novel lipoprotein (a) lowering drug, D-47, decreases neointima thickening after vascular injury.

Nakaya Y, Fukuda D, Oyamada T, Ogawa K, Harada N, Nakagami H, Morishita R, Sata M, Sakaue H.

J Med Invest. 2017;64(1.2):64-67. doi: 10.2152/jmi.64.64.

32.

Angiotensin II Peptide Vaccine Protects Ischemic Brain Through Reducing Oxidative Stress.

Wakayama K, Shimamura M, Suzuki JI, Watanabe R, Koriyama H, Akazawa H, Nakagami H, Mochizuki H, Isobe M, Morishita R.

Stroke. 2017 May;48(5):1362-1368. doi: 10.1161/STROKEAHA.116.016269. Epub 2017 Mar 31.

PMID:
28364024
33.

Hepatocyte Growth Factor Prevented High-Fat Diet-Induced Obesity and Improved Insulin Resistance in Mice.

Muratsu J, Iwabayashi M, Sanada F, Taniyama Y, Otsu R, Rakugi H, Morishita R.

Sci Rep. 2017 Mar 9;7(1):130. doi: 10.1038/s41598-017-00199-4.

34.

A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction.

Watanabe R, Suzuki JI, Wakayama K, Maejima Y, Shimamura M, Koriyama H, Nakagami H, Kumagai H, Ikeda Y, Akazawa H, Morishita R, Komuro I, Isobe M.

Sci Rep. 2017 Mar 7;7:43920. doi: 10.1038/srep43920.

35.

Transplantation of lineage-negative stem cells in pterygopalatine artery ligation induced retinal ischemia-reperfusion injury in mice.

Minhas G, Prabhakar S, Morishita R, Shimamura M, Bansal R, Anand A.

Mol Cell Biochem. 2017 May;429(1-2):123-136. doi: 10.1007/s11010-017-2941-0. Epub 2017 Feb 16.

PMID:
28210901
36.

Angiotensin Receptor Blocker Protects Alzheimer's Disease Brain From Ischemic Insult.

Takeda S, Morishita R.

Am J Hypertens. 2017 Feb;30(2):110-111. doi: 10.1093/ajh/hpw158. Epub 2016 Dec 8. No abstract available.

PMID:
27932318
37.

Evaluating the potential of the GFAP-KLH immune-tolerizing vaccine for type 1 diabetes in mice.

Pang Z, Higuchi M, Koriyama H, Yoshida S, Kurinami H, Shimamura M, Takami Y, Rakugi H, Morishita R, Nakagami H.

FEBS Lett. 2017 Jan;591(1):129-136. doi: 10.1002/1873-3468.12511. Epub 2016 Dec 20.

38.

A Novel Therapeutic Peptide as a Partial Agonist of RANKL in Ischemic Stroke.

Kurinami H, Shimamura M, Nakagami H, Shimizu H, Koriyama H, Kawano T, Wakayama K, Mochizuki H, Rakugi H, Morishita R.

Sci Rep. 2016 Nov 29;6:38062. doi: 10.1038/srep38062.

39.

Are diuretic additives fit for uncontrolled hypertensive patients receiving telmisartan and amlodipine treatment?

Taniyama Y, Morishita R.

Hypertens Res. 2017 Apr;40(4):346-347. doi: 10.1038/hr.2016.154. Epub 2016 Nov 24. No abstract available.

PMID:
27881849
40.

Different roles played by periostin splice variants in retinal neovascularization.

Nakama T, Yoshida S, Ishikawa K, Kobayashi Y, Abe T, Kiyonari H, Shioi G, Katsuragi N, Ishibashi T, Morishita R, Taniyama Y.

Exp Eye Res. 2016 Dec;153:133-140. doi: 10.1016/j.exer.2016.10.012. Epub 2016 Oct 12.

PMID:
27744020
41.

Activated Factor X Induces Endothelial Cell Senescence Through IGFBP-5.

Sanada F, Taniyama Y, Muratsu J, Otsu R, Iwabayashi M, Carracedo M, Rakugi H, Morishita R.

Sci Rep. 2016 Oct 18;6:35580. doi: 10.1038/srep35580.

42.

Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage.

Sakamaki K, Ishii TM, Sakata T, Takemoto K, Takagi C, Takeuchi A, Morishita R, Takahashi H, Nozawa A, Shinoda H, Chiba K, Sugimoto H, Saito A, Tamate S, Satou Y, Jung SK, Matsuoka S, Koyamada K, Sawasaki T, Nagai T, Ueno N.

Biochim Biophys Acta. 2016 Nov;1863(11):2766-2783. doi: 10.1016/j.bbamcr.2016.08.010. Epub 2016 Aug 23.

43.

Essential role of the nuclear isoform of RBFOX1, a candidate gene for autism spectrum disorders, in the brain development.

Hamada N, Ito H, Nishijo T, Iwamoto I, Morishita R, Tabata H, Momiyama T, Nagata K.

Sci Rep. 2016 Aug 2;6:30805. doi: 10.1038/srep30805.

44.

RANKL system in vascular and valve calcification with aging.

Kawakami R, Nakagami H, Noma T, Ohmori K, Kohno M, Morishita R.

Inflamm Regen. 2016 Aug 1;36:10. doi: 10.1186/s41232-016-0016-3. eCollection 2016. Review.

45.

Visualizing septin and cell dynamics in mammalian brain slices.

Ito H, Morishita R, Tabata H, Nagata K.

Methods Cell Biol. 2016;136:295-309. doi: 10.1016/bs.mcb.2016.03.016. Epub 2016 Apr 14.

PMID:
27473916
46.

Therapeutic effect of intra-articular injection of ribbon-type decoy oligonucleotides for hypoxia inducible factor-1 on joint contracture in an immobilized knee animal model.

Sotobayashi D, Kawahata H, Anada N, Ogihara T, Morishita R, Aoki M.

J Gene Med. 2016 Aug;18(8):180-92. doi: 10.1002/jgm.2891.

PMID:
27352194
47.

Influence of periostin-positive cell-specific Klf5 deletion on aortic thickening in DOCA-salt hypertensive mice.

Zempo H, Suzuki JI, Ogawa M, Watanabe R, Fujiu K, Manabe I, Conway SJ, Taniyama Y, Morishita R, Hirata Y, Isobe M, Nagai R.

Hypertens Res. 2016 Nov;39(11):764-768. doi: 10.1038/hr.2016.65. Epub 2016 Jun 23.

48.

Identification of striated muscle activator of Rho signaling (STARS) as a novel calmodulin target by a newly developed genome-wide screen.

Furuya Y, Denda M, Sakane K, Ogusu T, Takahashi S, Magari M, Kanayama N, Morishita R, Tokumitsu H.

Cell Calcium. 2016 Jul;60(1):32-40. doi: 10.1016/j.ceca.2016.04.004. Epub 2016 Apr 21.

PMID:
27132186
49.

Schizophrenia susceptibility gene product dysbindin-1 regulates the homeostasis of cyclin D1.

Ito H, Morishita R, Nagata K.

Biochim Biophys Acta. 2016 Aug;1862(8):1383-91. doi: 10.1016/j.bbadis.2016.04.016. Epub 2016 Apr 27.

50.

Induction of Angiogenesis by a Type III Phosphodiesterase Inhibitor, Cilostazol, Through Activation of Peroxisome Proliferator-Activated Receptor-γ and cAMP Pathways in Vascular Cells.

Sanada F, Kanbara Y, Taniyama Y, Otsu R, Carracedo M, Ikeda-Iwabu Y, Muratsu J, Sugimoto K, Yamamoto K, Rakugi H, Morishita R.

Arterioscler Thromb Vasc Biol. 2016 Mar;36(3):545-52. doi: 10.1161/ATVBAHA.115.307011. Epub 2016 Jan 14.

PMID:
26769045

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