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Sequence analysis of isolates of Aspergillus from patients with chronic and allergic aspergillosis reveals a spectrum of cryptic species.

Bongomin F, Moore CB, Masania R, Rowbotham E, Alastruey-Izquierdo A, Novak-Frazer L, Richardson MD.

Future Microbiol. 2018 Nov;13:1557-1563. doi: 10.2217/fmb-2018-0178. Epub 2018 Nov 12.


A novel role for CRIM1 in the corneal response to UV and pterygium development.

Maurizi E, Schiroli D, Atkinson SD, Mairs L, Courtney DG, O'Hagan B, McGilligan VE, Pagnamenta AT, Taylor JC, Vasquez JJD, Illanes-Velarde DE, Goldsmith D, Gouws P, Moore JE, Nesbit MA, Moore CBT.

Exp Eye Res. 2018 Oct 24;179:75-92. doi: 10.1016/j.exer.2018.10.012. [Epub ahead of print]


Impact of a diagnostics-driven antifungal stewardship programme in a UK tertiary referral teaching hospital.

Rautemaa-Richardson R, Rautemaa V, Al-Wathiqi F, Moore CB, Craig L, Felton TW, Muldoon EG.

J Antimicrob Chemother. 2018 Dec 1;73(12):3488-3495. doi: 10.1093/jac/dky360.


A case of pulmonary cryptococcoma due to Cryptococcus gattii in the United Kingdom.

Rodriguez-Goncer I, Bongomin F, Doran HM, Novak-Frazer L, Masania R, Moore CB, Richardson MD.

Med Mycol Case Rep. 2018 Mar 19;21:23-25. doi: 10.1016/j.mmcr.2018.03.007. eCollection 2018 Sep.


Gene editing in the context of an increasingly complex genome.

Blighe K, DeDionisio L, Christie KA, Chawes B, Shareef S, Kakouli-Duarte T, Chao-Shern C, Harding V, Kelly RS, Castellano L, Stebbing J, Lasky-Su JA, Nesbit MA, Moore CBT.

BMC Genomics. 2018 Aug 8;19(1):595. doi: 10.1186/s12864-018-4963-8. Review.


Deployed Military Medical Personnel: Impact of Combat and Healthcare Trauma Exposure.

Peterson AL, Baker MT, Moore CBA, Hale WJ, Joseph JS, Straud CL, Lancaster CL, McNally RJ, Isler WC, Litz BT, Mintz J.

Mil Med. 2018 Jun 19. doi: 10.1093/milmed/usy147. [Epub ahead of print]


Personalised genome editing - The future for corneal dystrophies.

Moore CBT, Christie KA, Marshall J, Nesbit MA.

Prog Retin Eye Res. 2018 Jul;65:147-165. doi: 10.1016/j.preteyeres.2018.01.004. Epub 2018 Jan 31. Review.


A systematic review of fluconazole resistance in clinical isolates of Cryptococcus species.

Bongomin F, Oladele RO, Gago S, Moore CB, Richardson MD.

Mycoses. 2018 May;61(5):290-297. doi: 10.1111/myc.12747. Epub 2018 Feb 14. Review.


Post-LASIK exacerbation of granular corneal dystrophy type 2 in members of a chinese family.

Chao-Shern C, Me R, DeDionisio LA, Ke BL, Nesbit MA, Marshall J, Moore CBT.

Eye (Lond). 2018 Jan;32(1):39-43. doi: 10.1038/eye.2017.265. Epub 2017 Dec 1.


Towards personalised allele-specific CRISPR gene editing to treat autosomal dominant disorders.

Christie KA, Courtney DG, DeDionisio LA, Shern CC, De Majumdar S, Mairs LC, Nesbit MA, Moore CBT.

Sci Rep. 2017 Nov 23;7(1):16174. doi: 10.1038/s41598-017-16279-4.


Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals.

Holzinger ER, Verma SS, Moore CB, Hall M, De R, Gilbert-Diamond D, Lanktree MB, Pankratz N, Amuzu A, Burt A, Dale C, Dudek S, Furlong CE, Gaunt TR, Kim DS, Riess H, Sivapalaratnam S, Tragante V, van Iperen EPA, Brautbar A, Carrell DS, Crosslin DR, Jarvik GP, Kuivaniemi H, Kullo IJ, Larson EB, Rasmussen-Torvik LJ, Tromp G, Baumert J, Cruickshanks KJ, Farrall M, Hingorani AD, Hovingh GK, Kleber ME, Klein BE, Klein R, Koenig W, Lange LA, Mӓrz W, North KE, Charlotte Onland-Moret N, Reiner AP, Talmud PJ, van der Schouw YT, Wilson JG, Kivimaki M, Kumari M, Moore JH, Drenos F, Asselbergs FW, Keating BJ, Ritchie MD.

BioData Min. 2017 Jul 24;10:25. doi: 10.1186/s13040-017-0145-5. eCollection 2017.


Comparative performance of Aspergillus galactomannan ELISA and PCR in sputum from patients with ABPA and CPA.

Fayemiwo S, Moore CB, Foden P, Denning DW, Richardson MD.

J Microbiol Methods. 2017 Sep;140:32-39. doi: 10.1016/j.mimet.2017.06.016. Epub 2017 Jun 21.


Increasing Access to Auricular Acupuncture for Postoperative Nausea and Vomiting.

Moore CB, Hickey AH.

J Perianesth Nurs. 2017 Apr;32(2):96-105. doi: 10.1016/j.jopan.2015.06.006. Epub 2016 Jun 25.


First isolation of the pan-azole-resistant Aspergillus fumigatus cyp51A TR46/Y121F/T289A mutant in a UK patient.

Moore CB, Novak-Frazer L, Muldoon E, Dunn KW, Masania R, Richardson MD, Rautemaa-Richardson R.

Int J Antimicrob Agents. 2017 Apr;49(4):512-514. doi: 10.1016/j.ijantimicag.2017.01.004. Epub 2017 Feb 9. No abstract available.


Association between hepatitis B co-infection and elevated liver stiffness among HIV-infected adults in Lusaka, Zambia.

Vinikoor MJ, Mulenga L, Siyunda A, Musukuma K, Chilengi R, Moore CB, Chi BH, Davies MA, Egger M, Wandeler G; International Epidemiologic Databases to Evaluate AIDS in Southern Africa (IeDEA-SA).

Trop Med Int Health. 2016 Nov;21(11):1435-1441. doi: 10.1111/tmi.12764. Epub 2016 Aug 30.


Potential Effects of Corneal Cross-Linking upon the Limbus.

Moore JE, Schiroli D, Moore CB.

Biomed Res Int. 2016;2016:5062064. Epub 2016 Sep 5. Review.


Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy.

Allen EH, Courtney DG, Atkinson SD, Moore JE, Mairs L, Poulsen ET, Schiroli D, Maurizi E, Cole C, Hickerson RP, James J, Murgatroyd H, Smith FJ, MacEwen C, Enghild JJ, Nesbit MA, Leslie Pedrioli DM, McLean WH, Moore CB.

Hum Mol Genet. 2016 Mar 15;25(6):1176-91. doi: 10.1093/hmg/ddw001. Epub 2016 Jan 11.


Can the accuracy of multifocal intraocular lens power calculation be improved to make patients spectacle free?

Ramji H, Moore J, Moore CB, Shah S.

Cont Lens Anterior Eye. 2016 Apr;39(2):160-6. doi: 10.1016/j.clae.2015.10.005. Epub 2015 Dec 28.


Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR).

De R, Verma SS, Drenos F, Holzinger ER, Holmes MV, Hall MA, Crosslin DR, Carrell DS, Hakonarson H, Jarvik G, Larson E, Pacheco JA, Rasmussen-Torvik LJ, Moore CB, Asselbergs FW, Moore JH, Ritchie MD, Keating BJ, Gilbert-Diamond D.

BioData Min. 2015 Dec 14;8:41. doi: 10.1186/s13040-015-0074-0. eCollection 2015.


CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting.

Courtney DG, Moore JE, Atkinson SD, Maurizi E, Allen EH, Pedrioli DM, McLean WH, Nesbit MA, Moore CB.

Gene Ther. 2016 Jan;23(1):108-12. doi: 10.1038/gt.2015.82. Epub 2015 Aug 20.


Protein Composition of TGFBI-R124C- and TGFBI-R555W-Associated Aggregates Suggests Multiple Mechanisms Leading to Lattice and Granular Corneal Dystrophy.

Courtney DG, Poulsen ET, Kennedy S, Moore JE, Atkinson SD, Maurizi E, Nesbit MA, Moore CB, Enghild JJ.

Invest Ophthalmol Vis Sci. 2015 Jul;56(8):4653-61. doi: 10.1167/iovs.15-16922.


Prospective multicenter international surveillance of azole resistance in Aspergillus fumigatus.

van der Linden JW, Arendrup MC, Warris A, Lagrou K, Pelloux H, Hauser PM, Chryssanthou E, Mellado E, Kidd SE, Tortorano AM, Dannaoui E, Gaustad P, Baddley JW, Uekötter A, Lass-Flörl C, Klimko N, Moore CB, Denning DW, Pasqualotto AC, Kibbler C, Arikan-Akdagli S, Andes D, Meletiadis J, Naumiuk L, Nucci M, Melchers WJ, Verweij PE.

Emerg Infect Dis. 2015 Jun;21(6):1041-4. doi: 10.3201/eid2106.140717.


Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.

Moore CB, Verma A, Pendergrass S, Verma SS, Johnson DH, Daar ES, Gulick RM, Haubrich R, Robbins GK, Ritchie MD, Haas DW.

Open Forum Infect Dis. 2015 Jan 9;2(1):ofu113. doi: 10.1093/ofid/ofu113. eCollection 2015 Jan.


Quality of Care and Service Expansion for HIV Care and Treatment.

Moore CB, Ciaraldi E.

Curr HIV/AIDS Rep. 2015 Jun;12(2):223-30. doi: 10.1007/s11904-015-0263-y. Review.


Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using biofilter, and gene-environment interactions using the Phenx Toolkit*.

Pendergrass SA, Verma SS, Hall MA, Holzinger ER, Moore CB, Wallace JR, Dudek SM, Huggins W, Kitchner T, Waudby C, Berg R, Mccarty CA, Ritchie MD.

Pac Symp Biocomput. 2015:495-505. Erratum in: Pac Symp Biocomput. 2015 ;20:493.


Changes in cellular immune activation and memory T-cell subsets in HIV-infected Zambian children receiving HAART.

Rainwater-Lovett K, Nkamba H, Mubiana-Mbewe M, Moore CB, Margolick J, Moss WJ.

J Acquir Immune Defic Syndr. 2014 Dec 15;67(5):455-62. doi: 10.1097/QAI.0000000000000342.


siRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy.

Courtney DG, Atkinson SD, Allen EH, Moore JE, Walsh CP, Pedrioli DM, MacEwen CJ, Pellegrini G, Maurizi E, Serafini C, Fantacci M, Liao H, Irvine AD, McLean WH, Moore CB.

Invest Ophthalmol Vis Sci. 2014 May 6;55(5):3352-60. doi: 10.1167/iovs.13-12957.


Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth.

Stanley SA, Barczak AK, Silvis MR, Luo SS, Sogi K, Vokes M, Bray MA, Carpenter AE, Moore CB, Siddiqi N, Rubin EJ, Hung DT.

PLoS Pathog. 2014 Feb 20;10(2):e1003946. doi: 10.1371/journal.ppat.1003946. eCollection 2014 Feb.


Development of allele-specific gene-silencing siRNAs for TGFBI Arg124Cys in lattice corneal dystrophy type I.

Courtney DG, Atkinson SD, Moore JE, Maurizi E, Serafini C, Pellegrini G, Black GC, Manson FD, Yam GH, Macewen CJ, Allen EH, McLean WH, Moore CB.

Invest Ophthalmol Vis Sci. 2014 Feb 18;55(2):977-85. doi: 10.1167/iovs.13-13279.


Low frequency variants, collapsed based on biological knowledge, uncover complexity of population stratification in 1000 genomes project data.

Moore CB, Wallace JR, Wolfe DJ, Frase AT, Pendergrass SA, Weiss KM, Ritchie MD.

PLoS Genet. 2013;9(12):e1003959. doi: 10.1371/journal.pgen.1003959. Epub 2013 Dec 26.


Managing multiple funding streams and agendas to achieve local and global health and research objectives: lessons from the field.

Holmes CB, Sikazwe I, Raelly RL, Freeman BL, Wambulawae I, Silwizya G, Topp SM, Chilengi R, Henostroza G, Kapambwe S, Simbeye D, Sibajene S, Chi H, Godfrey K, Chi B, Moore CB.

J Acquir Immune Defic Syndr. 2014 Jan 1;65 Suppl 1:S32-5. doi: 10.1097/QAI.0000000000000043.


Antiretroviral therapy restores age-dependent loss of resting memory B cells in young HIV-infected Zambian children.

Rainwater-Lovett K, Nkamba HC, Mubiana-Mbewe M, Moore CB, Margolick JB, Moss WJ.

J Acquir Immune Defic Syndr. 2014 Apr 15;65(5):505-9. doi: 10.1097/QAI.0000000000000074.


Protection of corneal epithelial stem cells prevents ultraviolet A damage during corneal collagen cross-linking treatment for keratoconus.

Moore JE, Atkinson SD, Azar DT, Worthington J, Downes CS, Courtney DG, Moore CB.

Br J Ophthalmol. 2014 Feb;98(2):270-4. doi: 10.1136/bjophthalmol-2013-303816. Epub 2013 Nov 28.


In vitro susceptibility of Aspergillus fumigatus to isavuconazole: correlation with itraconazole, voriconazole, and posaconazole.

Gregson L, Goodwin J, Johnson A, McEntee L, Moore CB, Richardson M, Hope WW, Howard SJ.

Antimicrob Agents Chemother. 2013 Nov;57(11):5778-80. doi: 10.1128/AAC.01141-13. Epub 2013 Sep 16.


Interlaboratory variability of Caspofungin MICs for Candida spp. Using CLSI and EUCAST methods: should the clinical laboratory be testing this agent?

Espinel-Ingroff A, Arendrup MC, Pfaller MA, Bonfietti LX, Bustamante B, Canton E, Chryssanthou E, Cuenca-Estrella M, Dannaoui E, Fothergill A, Fuller J, Gaustad P, Gonzalez GM, Guarro J, Lass-Flörl C, Lockhart SR, Meis JF, Moore CB, Ostrosky-Zeichner L, Pelaez T, Pukinskas SR, St-Germain G, Szeszs MW, Turnidge J.

Antimicrob Agents Chemother. 2013 Dec;57(12):5836-42. doi: 10.1128/AAC.01519-13. Epub 2013 Sep 9.


Discovery of selective small molecule type III phosphatidylinositol 4-kinase alpha (PI4KIIIα) inhibitors as anti hepatitis C (HCV) agents.

Leivers AL, Tallant M, Shotwell JB, Dickerson S, Leivers MR, McDonald OB, Gobel J, Creech KL, Strum SL, Mathis A, Rogers S, Moore CB, Botyanszki J.

J Med Chem. 2014 Mar 13;57(5):2091-106. doi: 10.1021/jm400781h. Epub 2013 Aug 14.


BioBin: a bioinformatics tool for automating the binning of rare variants using publicly available biological knowledge.

Moore CB, Wallace JR, Frase AT, Pendergrass SA, Ritchie MD.

BMC Med Genomics. 2013;6 Suppl 2:S6. doi: 10.1186/1755-8794-6-S2-S6. Epub 2013 May 7.


Primary ear fibroblast derivation from mice.

Moore CB, Allen IC.

Methods Mol Biol. 2013;1031:65-70. doi: 10.1007/978-1-62703-481-4_8.


Volume dependency for culture of fungi from respiratory secretions and increased sensitivity of Aspergillus quantitative PCR.

Fraczek MG, Kirwan MB, Moore CB, Morris J, Denning DW, Richardson MD.

Mycoses. 2014 Feb;57(2):69-78. doi: 10.1111/myc.12103. Epub 2013 Jun 21.


The cdr1B efflux transporter is associated with non-cyp51a-mediated itraconazole resistance in Aspergillus fumigatus.

Fraczek MG, Bromley M, Buied A, Moore CB, Rajendran R, Rautemaa R, Ramage G, Denning DW, Bowyer P.

J Antimicrob Chemother. 2013 Jul;68(7):1486-96. doi: 10.1093/jac/dkt075. Epub 2013 Apr 10.


Using BioBin to explore rare variant population stratification.

Moore CB, Wallace JR, Frase AT, Pendergrass SA, Ritchie MD.

Pac Symp Biocomput. 2013:332-43.


Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using Biofilter, and gene-environment interactions using the PhenX Toolkit.

Pendergrass SA, Verma SS, Holzinger ER, Moore CB, Wallace J, Dudek SM, Huggins W, Kitchner T, Waudby C, Berg R, McCarty CA, Ritchie MD.

Pac Symp Biocomput. 2013:147-58. Corrected and republished in: Pac Symp Biocomput. 2015;:495-505.


Performance of two Aspergillus IgG EIA assays compared with the precipitin test in chronic and allergic aspergillosis.

Baxter CG, Denning DW, Jones AM, Todd A, Moore CB, Richardson MD.

Clin Microbiol Infect. 2013 Apr;19(4):E197-204. doi: 10.1111/1469-0691.12133. Epub 2013 Jan 18.


Allele-specific siRNA silencing for the common keratin 12 founder mutation in Meesmann epithelial corneal dystrophy.

Allen EHA, Atkinson SD, Liao H, Moore JE, Pedrioli DML, Smith FJD, McLean WHI, Moore CBT.

Invest Ophthalmol Vis Sci. 2013 Jan 17;54(1):494-502. doi: 10.1167/iovs.12-10528.


High-level expression of cyp51B in azole-resistant clinical Aspergillus fumigatus isolates.

Buied A, Moore CB, Denning DW, Bowyer P.

J Antimicrob Chemother. 2013 Mar;68(3):512-4. doi: 10.1093/jac/dks451. Epub 2012 Dec 2.


IgE-mediated immune responses and airway detection of Aspergillus and Candida in adult cystic fibrosis.

Baxter CG, Moore CB, Jones AM, Webb AK, Denning DW.

Chest. 2013 May;143(5):1351-1357. doi: 10.1378/chest.12-1363.


Immunologic risk factors for early mortality after starting antiretroviral therapy in HIV-infected Zambian children.

Rainwater-Lovett K, Nkamba HC, Mubiana-Mbewe M, Moore CB, Moss WJ.

AIDS Res Hum Retroviruses. 2013 Mar;29(3):479-87. doi: 10.1089/AID.2012.0246. Epub 2012 Oct 31.


Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.

Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Goldberg L, Birger Y, Izraeli S, Gamis AS, Smith FO, Woods WG, Taub J, Scherer CA, Bradner JE, Goh BC, Mercher T, Carpenter AE, Gould RJ, Clemons PA, Carr SA, Root DE, Schreiber SL, Stern AM, Crispino JD.

Cell. 2012 Aug 3;150(3):575-89. doi: 10.1016/j.cell.2012.06.032.


The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.

Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania B, Moore CB, Giguère PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, Chen X, Ting JP.

Immunity. 2012 Jun 29;36(6):933-46. doi: 10.1016/j.immuni.2012.03.025.


Enhancement of the anti-Salmonella immune response in CD154-deficient mice by an attenuated, IFN-γ-expressing, strain of Salmonella enterica serovar Typhimurium.

Al-Ojali SM, Moore CB, Fernandez-Cabezudo MJ, Al-Ramadi BK.

Microb Pathog. 2012 Jun;52(6):326-35. doi: 10.1016/j.micpath.2012.03.002. Epub 2012 Mar 13.


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