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Items: 1 to 50 of 283

1.

Whole-Exome Sequencing to Identify Rare Variants and Gene Networks that Increase Susceptibility to Scleroderma in African Americans.

Gourh P, Remmers EF, Boyden SE, Alexander T, Morgan ND, Shah AA, Mayes MD, Doumatey A, Bentley AR, Shriner D, Domsic RT, Medsger TA Jr, Steen VD, Ramos PS, Silver RM, Korman B, Varga J, Schiopu E, Khanna D, Hsu V, Gordon JK, Saketkoo LA, Gladue H, Kron B, Criswell LA, Derk CT, Bridges SL Jr, Shanmugam VK, Kolstad KD, Chung L, Jan R, Bernstein EJ, Goldberg A, Trojanowski M, Kafaja S, Maksimowicz-McKinnon KM, Mullikin JC; NISC Comparative Sequencing Program, Adeyemo A, Rotimi C, Boin F, Kastner DL, Wigley FM.

Arthritis Rheumatol. 2018 May 6. doi: 10.1002/art.40541. [Epub ahead of print]

PMID:
29732714
2.

Clinical and serological features of systemic sclerosis in a multicenter African American cohort: Analysis of the genome research in African American scleroderma patients clinical database.

Morgan ND, Shah AA, Mayes MD, Domsic RT, Medsger TA Jr, Steen VD, Varga J, Carns M, Ramos PS, Silver RM, Schiopu E, Khanna D, Hsu V, Gordon JK, Gladue H, Saketkoo LA, Criswell LA, Derk CT, Trojanowski MA, Shanmugam VK, Chung L, Valenzuela A, Jan R, Goldberg A, Remmers EF, Kastner DL, Wigley FM, Gourh P, Boin F.

Medicine (Baltimore). 2017 Dec;96(51):e8980. doi: 10.1097/MD.0000000000008980.

3.

14-3-3z sequesters cytosolic T-bet, upregulating IL-13 levels in TC2 and CD8+ lymphocytes from patients with scleroderma.

Cascio S, Medsger TA Jr, Hawse WF, Watkins SC, Milcarek C, Moreland LW, Lafyatis RA, Fuschiotti P.

J Allergy Clin Immunol. 2018 Jul;142(1):109-119.e6. doi: 10.1016/j.jaci.2017.10.029. Epub 2017 Nov 15.

PMID:
29155097
4.

There is a need for new systemic sclerosis subset criteria. A content analytic approach.

Johnson SR, Soowamber ML, Fransen J, Khanna D, Van Den Hoogen F, Baron M, Matucci-Cerinic M, Denton CP, Medsger TA Jr, Carreira PE, Riemekasten G, Distler J, Gabrielli A, Steen V, Chung L, Silver R, Varga J, Müller-Ladner U, Vonk MC, Walker UA, Wollheim FA, Herrick A, Furst DE, Czirjak L, Kowal-Bielecka O, Del Galdo F, Cutolo M, Hunzelmann N, Murray CD, Foeldvari I, Mouthon L, Damjanov N, Kahaleh B, Frech T, Assassi S, Saketkoo LA, Pope JE.

Scand J Rheumatol. 2018 Jan;47(1):62-70. doi: 10.1080/03009742.2017.1299793. Epub 2017 Oct 9.

PMID:
28990485
5.

Skin-Resident Effector Memory CD8+CD28- T Cells Exhibit a Profibrotic Phenotype in Patients with Systemic Sclerosis.

Li G, Larregina AT, Domsic RT, Stolz DB, Medsger TA Jr, Lafyatis R, Fuschiotti P.

J Invest Dermatol. 2017 May;137(5):1042-1050. doi: 10.1016/j.jid.2016.11.037. Epub 2016 Dec 22.

6.

Utility of B-type natriuretic peptides in the assessment of patients with systemic sclerosis-associated pulmonary hypertension in the PHAROS registry.

Chung L, Fairchild RM, Furst DE, Li S, Alkassab F, Bolster MB, Csuka ME, Derk CT, Domsic RT, Fischer A, Frech TM, Gomberg-Maitland M, Gordon JK, Hinchcliff M, Hsu V, Hummers LK, Khanna D, Medsger TAJ, Molitor JA, Preston IR, Schiopu E, Shapiro L, Hant F, Silver R, Simms R, Varga J, Steen VD, Zamanian RT.

Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):106-113. Epub 2016 Nov 10.

PMID:
27908301
7.

Brief Report: HLA-DRB1, DQA1, and DQB1 in Juvenile-Onset Systemic Sclerosis.

Stevens AM, Kanaan SB, Torok KS, Medsger TA, Mayes MD, Reveille JD, Klein-Gitelman M, Reed AM, Lee T, Li SC, Henstorf G, Luu C, Aydelotte T, Nelson JL.

Arthritis Rheumatol. 2016 Nov;68(11):2772-2777. doi: 10.1002/art.39765. Epub 2016 Oct 6.

8.

Reply.

Domsic RT, Lucas M, Nihtyanova SI, Denton CP, Wisniewski SR, Fine MJ, Kwoh CK, Medsger TA Jr.

Arthritis Rheumatol. 2017 Jan;69(1):242. doi: 10.1002/art.39853. No abstract available.

9.

Calcinosis is associated with digital ulcers and osteoporosis in patients with systemic sclerosis: A Scleroderma Clinical Trials Consortium study.

Valenzuela A, Baron M; Canadian Scleroderma Research Group, Herrick AL, Proudman S, Stevens W; Australian Scleroderma Interest Group, Rodriguez-Reyna TS, Vacca A, Medsger TA Jr, Hinchcliff M, Hsu V, Wu JY, Fiorentino D, Chung L.

Semin Arthritis Rheum. 2016 Dec;46(3):344-349. doi: 10.1016/j.semarthrit.2016.05.008. Epub 2016 Jun 2.

10.

Gender differences in systemic sclerosis: relationship to clinical features, serologic status and outcomes.

Peoples C, Medsger TA Jr, Lucas M, Rosario BL, Feghali-Bostwick CA.

J Scleroderma Relat Disord. 2016 May-Aug;1(2):177-240. doi: 10.5301/jsrd.5000209. Epub 2016 Jul 23.

11.

Derivation and External Validation of a Prediction Rule for Five-Year Mortality in Patients With Early Diffuse Cutaneous Systemic Sclerosis.

Domsic RT, Nihtyanova SI, Wisniewski SR, Fine MJ, Lucas M, Kwoh CK, Denton CP, Medsger TA Jr.

Arthritis Rheumatol. 2016 Apr;68(4):993-1003. doi: 10.1002/art.39490. Erratum in: Arthritis Rheumatol. 2016 Nov;68(11):2751.

12.

Progress in the evolution of systemic sclerosis classification criteria and recommendation for additional comparative specificity studies.

Masi AT, Medsger TA Jr.

J Rheumatol. 2015 Jan;42(1):8-10. doi: 10.3899/jrheum.141020. No abstract available.

PMID:
25554803
13.

Endothelial dysfunction is present only in the microvasculature and microcirculation of early diffuse systemic sclerosis patients.

Domsic RT, Dezfulian C, Shoushtari A, Ivanco D, Kenny E, Kwoh CK, Medsger TA Jr, Champion HC.

Clin Exp Rheumatol. 2014 Nov-Dec;32(6 Suppl 86):S-154-60. Epub 2014 Nov 5.

14.

Multicriteria decision analysis methods with 1000Minds for developing systemic sclerosis classification criteria.

Johnson SR, Naden RP, Fransen J, van den Hoogen F, Pope JE, Baron M, Tyndall A, Matucci-Cerinic M, Denton CP, Distler O, Gabrielli A, van Laar JM, Mayes M, Steen V, Seibold JR, Clements P, Medsger TA Jr, Carreira PE, Riemekasten G, Chung L, Fessler BJ, Merkel PA, Silver R, Varga J, Allanore Y, Mueller-Ladner U, Vonk MC, Walker UA, Cappelli S, Khanna D.

J Clin Epidemiol. 2014 Jun;67(6):706-14. doi: 10.1016/j.jclinepi.2013.12.009. Epub 2014 Apr 8.

15.

Localized scleroderma and regional inflammatory myopathy.

Zivković SA, Freiberg W, Lacomis D, Domsic RT, Medsger TA.

Neuromuscul Disord. 2014 May;24(5):425-30. doi: 10.1016/j.nmd.2014.01.012. Epub 2014 Feb 1.

PMID:
24569141
16.

Derivation and validation of a prediction rule for two-year mortality in early diffuse cutaneous systemic sclerosis.

Domsic RT, Nihtyanova SI, Wisniewski SR, Fine MJ, Lucas M, Kwoh CK, Denton CP, Medsger TA Jr.

Arthritis Rheumatol. 2014 Jun;66(6):1616-24. doi: 10.1002/art.38381.

17.

2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative.

van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, Matucci-Cerinic M, Naden RP, Medsger TA Jr, Carreira PE, Riemekasten G, Clements PJ, Denton CP, Distler O, Allanore Y, Furst DE, Gabrielli A, Mayes MD, van Laar JM, Seibold JR, Czirjak L, Steen VD, Inanc M, Kowal-Bielecka O, Müller-Ladner U, Valentini G, Veale DJ, Vonk MC, Walker UA, Chung L, Collier DH, Csuka ME, Fessler BJ, Guiducci S, Herrick A, Hsu VM, Jimenez S, Kahaleh B, Merkel PA, Sierakowski S, Silver RM, Simms RW, Varga J, Pope JE.

Arthritis Rheum. 2013 Nov;65(11):2737-47. doi: 10.1002/art.38098. Epub 2013 Oct 3.

18.

2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative.

van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, Matucci-Cerinic M, Naden RP, Medsger TA Jr, Carreira PE, Riemekasten G, Clements PJ, Denton CP, Distler O, Allanore Y, Furst DE, Gabrielli A, Mayes MD, van Laar JM, Seibold JR, Czirjak L, Steen VD, Inanc M, Kowal-Bielecka O, Müller-Ladner U, Valentini G, Veale DJ, Vonk MC, Walker UA, Chung L, Collier DH, Ellen Csuka M, Fessler BJ, Guiducci S, Herrick A, Hsu VM, Jimenez S, Kahaleh B, Merkel PA, Sierakowski S, Silver RM, Simms RW, Varga J, Pope JE.

Ann Rheum Dis. 2013 Nov;72(11):1747-55. doi: 10.1136/annrheumdis-2013-204424.

PMID:
24092682
19.

Autoantibodies to RuvBL1 and RuvBL2: a novel systemic sclerosis-related antibody associated with diffuse cutaneous and skeletal muscle involvement.

Kaji K, Fertig N, Medsger TA Jr, Satoh T, Hoshino K, Hamaguchi Y, Hasegawa M, Lucas M, Schnure A, Ogawa F, Sato S, Takehara K, Fujimoto M, Kuwana M.

Arthritis Care Res (Hoboken). 2014 Apr;66(4):575-84. doi: 10.1002/acr.22163.

20.

Survival and predictors of mortality in systemic sclerosis-associated pulmonary arterial hypertension: outcomes from the pulmonary hypertension assessment and recognition of outcomes in scleroderma registry.

Chung L, Domsic RT, Lingala B, Alkassab F, Bolster M, Csuka ME, Derk C, Fischer A, Frech T, Furst DE, Gomberg-Maitland M, Hinchcliff M, Hsu V, Hummers LK, Khanna D, Medsger TA Jr, Molitor JA, Preston IR, Schiopu E, Shapiro L, Silver R, Simms R, Varga J, Gordon JK, Steen VD.

Arthritis Care Res (Hoboken). 2014 Mar;66(3):489-95. doi: 10.1002/acr.22121.

21.

Significance of palpable tendon friction rubs in early diffuse cutaneous systemic sclerosis.

Doré A, Lucas M, Ivanco D, Medsger TA Jr, Domsic RT.

Arthritis Care Res (Hoboken). 2013 Aug;65(8):1385-9. doi: 10.1002/acr.21964.

22.

Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis.

Aida-Yasuoka K, Peoples C, Yasuoka H, Hershberger P, Thiel K, Cauley JA, Medsger TA Jr, Feghali-Bostwick CA.

Arthritis Res Ther. 2013 Jan 10;15(1):R10. doi: 10.1186/ar4140.

23.

Interleukin-13-producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis.

Fuschiotti P, Larregina AT, Ho J, Feghali-Bostwick C, Medsger TA Jr.

Arthritis Rheum. 2013 Jan;65(1):236-46. doi: 10.1002/art.37706.

24.

A clinical and serologic comparison of African American and Caucasian patients with systemic sclerosis.

Steen V, Domsic RT, Lucas M, Fertig N, Medsger TA Jr.

Arthritis Rheum. 2012 Sep;64(9):2986-94. doi: 10.1002/art.34482.

25.

Anti-PM-Scl antibody in patients with systemic sclerosis.

Koschik RW 2nd, Fertig N, Lucas MR, Domsic RT, Medsger TA Jr.

Clin Exp Rheumatol. 2012 Mar-Apr;30(2 Suppl 71):S12-6. Epub 2012 May 29.

PMID:
22261302
26.

Commentary on myofascial release therapy in systemic lupus erythematosus and scleroderma.

Masi AT, Medsger TA Jr, Betts SJ.

J Bodyw Mov Ther. 2012 Jan;16(1):2-4; author reply 4-6. doi: 10.1016/j.jbmt.2011.09.001. Epub 2011 Oct 2. No abstract available.

PMID:
22196419
27.

Validation of potential classification criteria for systemic sclerosis.

Johnson SR, Fransen J, Khanna D, Baron M, van den Hoogen F, Medsger TA Jr, Peschken CA, Carreira PE, Riemekasten G, Tyndall A, Matucci-Cerinic M, Pope JE.

Arthritis Care Res (Hoboken). 2012 Mar;64(3):358-67. doi: 10.1002/acr.20684.

28.

Items for developing revised classification criteria in systemic sclerosis: Results of a consensus exercise.

Fransen J, Johnson SR, van den Hoogen F, Baron M, Allanore Y, Carreira PE, Czirják L, Denton CP, Distler O, Furst DE, Gabrielli A, Herrick A, Inanc M, Kahaleh B, Kowal-Bielecka O, Medsger TA Jr, Mueller-Ladner U, Riemekasten G, Sierakowski S, Valentini G, Veale D, Vonk MC, Walker U, Chung L, Clements PJ, Collier DH, Csuka ME, Jimenez S, Merkel PA, Seibold JR, Silver R, Steen V, Tyndall A, Matucci-Cerinic M, Pope JE, Khanna D.

Arthritis Care Res (Hoboken). 2012 Mar;64(3):351-7. doi: 10.1002/acr.20679.

29.

Connective tissue diseases: Predicting death in SSc: planning and cooperation are needed.

Domsic RT, Medsger TA Jr.

Nat Rev Rheumatol. 2011 Oct 4;7(11):628-30. doi: 10.1038/nrrheum.2011.152. No abstract available.

30.

Localized expression of tenascin in systemic sclerosis-associated pulmonary fibrosis and its regulation by insulin-like growth factor binding protein 3.

Brissett M, Veraldi KL, Pilewski JM, Medsger TA Jr, Feghali-Bostwick CA.

Arthritis Rheum. 2012 Jan;64(1):272-80. doi: 10.1002/art.30647.

31.

Quality indicator set for systemic sclerosis.

Khanna D, Kowal-Bielecka O, Khanna PP, Lapinska A, Asch SM, Wenger N, Brown KK, Clements PJ, Getzug T, Mayes MD, Medsger TA, Oudiz R, Simms R, Steen V, Maranian P, Furst DE.

Clin Exp Rheumatol. 2011 Mar-Apr;29(2 Suppl 65):S33-9. Epub 2011 May 16.

32.

GATA-3 up-regulation in CD8+ T cells as a biomarker of immune dysfunction in systemic sclerosis, resulting in excessive interleukin-13 production.

Medsger TA Jr, Ivanco DE, Kardava L, Morel PA, Lucas MR, Fuschiotti P.

Arthritis Rheum. 2011 Jun;63(6):1738-47. doi: 10.1002/art.30489.

33.

Scleroderma renal crisis: a pathology perspective.

Batal I, Domsic RT, Medsger TA, Bastacky S.

Int J Rheumatol. 2010;2010:543704. doi: 10.1155/2010/543704. Epub 2010 Jul 28.

34.

Bosentan treatment of digital ulcers related to systemic sclerosis: results from the RAPIDS-2 randomised, double-blind, placebo-controlled trial.

Matucci-Cerinic M, Denton CP, Furst DE, Mayes MD, Hsu VM, Carpentier P, Wigley FM, Black CM, Fessler BJ, Merkel PA, Pope JE, Sweiss NJ, Doyle MK, Hellmich B, Medsger TA Jr, Morganti A, Kramer F, Korn JH, Seibold JR.

Ann Rheum Dis. 2011 Jan;70(1):32-8. doi: 10.1136/ard.2010.130658. Epub 2010 Aug 30.

35.

Reliability and validity of the delta finger-to-palm (FTP), a new measure of finger range of motion in systemic sclerosis.

Torok KS, Baker NA, Lucas M, Domsic RT, Boudreau R, Medsger TA Jr.

Clin Exp Rheumatol. 2010 Mar-Apr;28(2 Suppl 58):S28-36. Epub 2010 Jun 10.

36.

Skin thickness progression rate: a predictor of mortality and early internal organ involvement in diffuse scleroderma.

Domsic RT, Rodriguez-Reyna T, Lucas M, Fertig N, Medsger TA Jr.

Ann Rheum Dis. 2011 Jan;70(1):104-9. doi: 10.1136/ard.2009.127621. Epub 2010 Aug 2. Erratum in: Ann Rheum Dis. 2011 Jul;70(7):1350.

37.

Development and initial validation of the localized scleroderma skin damage index and physician global assessment of disease damage: a proof-of-concept study.

Arkachaisri T, Vilaiyuk S, Torok KS, Medsger TA Jr.

Rheumatology (Oxford). 2010 Feb;49(2):373-81. doi: 10.1093/rheumatology/kep361. Epub 2009 Dec 14.

38.

The localized scleroderma skin severity index and physician global assessment of disease activity: a work in progress toward development of localized scleroderma outcome measures.

Arkachaisri T, Vilaiyuk S, Li S, O'Neil KM, Pope E, Higgins GC, Punaro M, Rabinovich EC, Rosenkranz M, Kietz DA, Rosen P, Spalding SJ, Hennon TR, Torok KS, Cassidy E, Medsger TA Jr; Localized Scleroderma Clinical and Ultrasound Study Group.

J Rheumatol. 2009 Dec;36(12):2819-29. doi: 10.3899/jrheum.081284. Epub 2009 Oct 15.

39.

Ultraviolet radiation intensity predicts the relative distribution of dermatomyositis and anti-Mi-2 autoantibodies in women.

Love LA, Weinberg CR, McConnaughey DR, Oddis CV, Medsger TA Jr, Reveille JD, Arnett FC, Targoff IN, Miller FW.

Arthritis Rheum. 2009 Aug;60(8):2499-504. doi: 10.1002/art.24702.

40.

Anti-U11/U12 RNP antibodies in systemic sclerosis: a new serologic marker associated with pulmonary fibrosis.

Fertig N, Domsic RT, Rodriguez-Reyna T, Kuwana M, Lucas M, Medsger TA Jr, Feghali-Bostwick CA.

Arthritis Rheum. 2009 Jul 15;61(7):958-65. doi: 10.1002/art.24586.

41.

Recombinant human relaxin in the treatment of systemic sclerosis with diffuse cutaneous involvement: a randomized, double-blind, placebo-controlled trial.

Khanna D, Clements PJ, Furst DE, Korn JH, Ellman M, Rothfield N, Wigley FM, Moreland LW, Silver R, Kim YH, Steen VD, Firestein GS, Kavanaugh AF, Weisman M, Mayes MD, Collier D, Csuka ME, Simms R, Merkel PA, Medsger TA Jr, Sanders ME, Maranian P, Seibold JR; Relaxin Investigators and the Scleroderma Clinical Trials Consortium.

Arthritis Rheum. 2009 Apr;60(4):1102-11. doi: 10.1002/art.24380.

42.

Anti-U3 RNP autoantibodies in systemic sclerosis.

Aggarwal R, Lucas M, Fertig N, Oddis CV, Medsger TA Jr.

Arthritis Rheum. 2009 Apr;60(4):1112-8. doi: 10.1002/art.24409.

43.

Effector CD8+ T cells in systemic sclerosis patients produce abnormally high levels of interleukin-13 associated with increased skin fibrosis.

Fuschiotti P, Medsger TA Jr, Morel PA.

Arthritis Rheum. 2009 Apr;60(4):1119-28. doi: 10.1002/art.24432.

44.

Serum autoantibodies and their clinical associations in patients with childhood- and adult-onset linear scleroderma. A single-center study.

Arkachaisri T, Fertig N, Pino S, Medsger TA Jr.

J Rheumatol. 2008 Dec;35(12):2439-44. doi: 10.3899/jrheum.080098. Epub 2008 Nov 1.

PMID:
19004036
45.

Renal biopsy findings predicting outcome in scleroderma renal crisis.

Batal I, Domsic RT, Shafer A, Medsger TA Jr, Kiss LP, Randhawa P, Bastacky S.

Hum Pathol. 2009 Mar;40(3):332-40. doi: 10.1016/j.humpath.2008.08.001. Epub 2008 Oct 29.

PMID:
18973923
46.

Pulmonary arterial hypertension and severe pulmonary fibrosis in systemic sclerosis patients with a nucleolar antibody.

Steen VD, Lucas M, Fertig N, Medsger TA Jr.

J Rheumatol. 2007 Nov;34(11):2230-5. Epub 2007 Oct 15.

PMID:
17937469
47.

Clinical subsets, skin thickness progression rate, and serum antibody levels in systemic sclerosis patients with anti-topoisomerase I antibody.

Perera A, Fertig N, Lucas M, Rodriguez-Reyna TS, Hu P, Steen VD, Medsger TA Jr.

Arthritis Rheum. 2007 Aug;56(8):2740-6.

48.

The Pediatric Rheumatology European Society/American College of Rheumatology/European League against Rheumatism provisional classification criteria for juvenile systemic sclerosis.

Zulian F, Woo P, Athreya BH, Laxer RM, Medsger TA Jr, Lehman TJ, Cerinic MM, Martini G, Ravelli A, Russo R, Cuttica R, de Oliveira SK, Denton CP, Cozzi F, Foeldvari I, Ruperto N.

Arthritis Rheum. 2007 Mar 15;57(2):203-12.

49.

Changes in causes of death in systemic sclerosis, 1972-2002.

Steen VD, Medsger TA.

Ann Rheum Dis. 2007 Jul;66(7):940-4. Epub 2007 Feb 28.

50.

Outcome measurements in scleroderma: results from a delphi exercise.

Gazi H, Pope JE, Clements P, Medsger TA, Martin RW, Merkel PA, Kahaleh B, Wollheim FA, Baron M, Csuka ME, Emery P, Belch JF, Hayat S, Lally EV, Korn JH, Czirjak L, Herrick A, Voskuyl AE, Bruehlmann P, Inanc M, Furst DE, Black C, Ellman MH, Moreland LW, Rothfield NF, Hsu V, Mayes M, McKown KM, Krieg T, Siebold JR.

J Rheumatol. 2007 Mar;34(3):501-9. Epub 2007 Feb 1.

PMID:
17299843

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