Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 100

1.

Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN).

Martin MW, Lancia DR Jr, Li H, Schiller SER, Toms AV, Wang Z, Bair KW, Castro J, Fessler S, Gotur D, Hubbs SE, Kauffman GS, Kershaw M, Luke GP, McKinnon C, Yao L, Lu W, Millan DS.

Bioorg Med Chem Lett. 2019 Apr 15;29(8):1001-1006. doi: 10.1016/j.bmcl.2019.02.012. Epub 2019 Feb 11.

PMID:
30803804
2.

Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11.

Martin MW, Lee JY, Lancia DR Jr, Ng PY, Han B, Thomason JR, Lynes MS, Marshall CG, Conti C, Collis A, Morales MA, Doshi K, Rudnitskaya A, Yao L, Zheng X.

Bioorg Med Chem Lett. 2018 Jul 1;28(12):2143-2147. doi: 10.1016/j.bmcl.2018.05.021. Epub 2018 May 9.

PMID:
29776742
3.

Design and Optimization of Benzopiperazines as Potent Inhibitors of BET Bromodomains.

Millan DS, Kayser-Bricker KJ, Martin MW, Talbot AC, Schiller SER, Herbertz T, Williams GL, Luke GP, Hubbs S, Alvarez Morales MA, Cardillo D, Troccolo P, Mendes RL, McKinnon C.

ACS Med Chem Lett. 2017 Jul 14;8(8):847-852. doi: 10.1021/acsmedchemlett.7b00191. eCollection 2017 Aug 10.

4.

Chronic pain patients' perspectives of medical cannabis.

Piper BJ, Beals ML, Abess AT, Nichols SD, Martin MW, Cobb CM, DeKeuster RM.

Pain. 2017 Jul;158(7):1373-1379. doi: 10.1097/j.pain.0000000000000899.

5.

Corrigendum to "Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling" [Bioorg. Med. Chem. 24 (2016) 2215-2234].

Liu L, Lee MR, Kim JL, Whittington DA, Bregman H, Hua Z, Lewis RT, Martin MW, Nishimura N, Potashman M, Yang K, Yi S, Vaida KR, Epstein LF, Babij C, Fernando M, Carnahan J, Norman MH.

Bioorg Med Chem. 2016 Jul 1;24(13):3093. doi: 10.1016/j.bmc.2016.05.014. Epub 2016 May 24. No abstract available.

PMID:
27234892
6.

Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling.

Liu L, Lee MR, Kim JL, Whittington DA, Bregman H, Hua Z, Lewis RT, Martin MW, Nishimura N, Potashman M, Yang K, Yi S, Vaida KR, Epstein LF, Babij C, Fernando M, Carnahan J, Norman MH.

Bioorg Med Chem. 2016 May 15;24(10):2215-34. doi: 10.1016/j.bmc.2016.03.055. Epub 2016 Apr 13. Erratum in: Bioorg Med Chem. 2016 Jul 1;24(13):3093.

PMID:
27085672
7.

Paroxysmal atrial fibrillation in seven dogs with presumed neurally-mediated syncope.

Porteiro Vázquez DM, Perego M, Santos L, Gerou-Ferriani M, Martin MW, Santilli RA.

J Vet Cardiol. 2016 Mar;18(1):1-9. doi: 10.1016/j.jvc.2015.10.010. Epub 2016 Jan 18.

PMID:
26795971
8.

Frequency of exogenous hormone therapy impacts spermiation in male Fowler's toad (Bufo fowleri).

McDonough CE, Martin MW, Vance CK, Cole JA, Kouba AJ.

Reprod Fertil Dev. 2016 Jun;28(7):995-1003. doi: 10.1071/RD14214.

PMID:
25585046
9.

Notes from the field: the evaluation of Maine Nutrition and Physical Activity Self-Assessment for Child Care (NAPSACC) experience.

Martin SL, Martin MW, Cook B, Knaus R, O'Rourke K.

Eval Health Prof. 2015 Mar;38(1):140-5. doi: 10.1177/0163278714536032. Epub 2014 May 28.

PMID:
24872443
10.

Echo rounds: Transesophageal echocardiography: identification and management of a misplaced pedicle screw in the descending thoracic aorta after posterior spinal fusion.

Iyer MH, Engoren M, Martin MW.

Anesth Analg. 2013 Feb;116(2):303-6. doi: 10.1213/ANE.0b013e318275341d. Epub 2013 Jan 9. No abstract available.

PMID:
23302974
11.

Structure-Based Design of Potent and Selective CK1γ Inhibitors.

Huang H, Acquaviva L, Berry V, Bregman H, Chakka N, O'Connor A, DiMauro EF, Dovey J, Epstein O, Grubinska B, Goldstein J, Gunaydin H, Hua Z, Huang X, Huang L, Human J, Long A, Newcomb J, Patel VF, Saffran D, Serafino R, Schneider S, Strathdee C, Tang J, Turci S, White R, Yu V, Zhao H, Wilson C, Martin MW.

ACS Med Chem Lett. 2012 Oct 18;3(12):1059-64. doi: 10.1021/ml300278f. eCollection 2012 Dec 13.

12.

2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1γ) inhibitors.

Hua Z, Huang X, Bregman H, Chakka N, DiMauro EF, Doherty EM, Goldstein J, Gunaydin H, Huang H, Mercede S, Newcomb J, Patel VF, Turci SM, Yan J, Wilson C, Martin MW.

Bioorg Med Chem Lett. 2012 Sep 1;22(17):5392-5. doi: 10.1016/j.bmcl.2012.07.046. Epub 2012 Jul 20.

PMID:
22877629
13.

Association of QRS duration and survival in dogs with dilated cardiomyopathy: a retrospective study of 266 clinical cases.

Pedro BM, Alves JV, Cripps PJ, Stafford Johnson MJ, Martin MW.

J Vet Cardiol. 2011 Dec;13(4):243-9. doi: 10.1016/j.jvc.2011.09.003. Epub 2011 Nov 3.

PMID:
22051528
14.

Cardiothoracic anesthesiology fellowship: challenges of training and a novel approach to resident education.

Martin MW, Vance JL, Didier TJ.

J Cardiothorac Vasc Anesth. 2011 Dec;25(6):1204-6. doi: 10.1053/j.jvca.2011.08.016. Epub 2011 Oct 14. No abstract available.

PMID:
22000984
15.

Balloon dilation of an imperforate cor triatriatum dexter in a Golden Retriever with concurrent double-chambered right ventricle and subsequent evaluation by cardiac magnetic resonance imaging.

López-Alvarez J, Dukes-McEwan J, Martin MW, Killick D, Fonfara S, Fraser McConnell J.

J Vet Cardiol. 2011 Sep;13(3):211-8. doi: 10.1016/j.jvc.2011.04.004. Epub 2011 Aug 10.

PMID:
21835710
16.

Outcome in 55 dogs with pulmonic stenosis that did not undergo balloon valvuloplasty or surgery.

Francis AJ, Johnson MJ, Culshaw GC, Corcoran BM, Martin MW, French AT.

J Small Anim Pract. 2011 Jun;52(6):282-8. doi: 10.1111/j.1748-5827.2011.01059.x.

PMID:
21627655
17.

Cardiomyopathy in Boxer dogs: a retrospective study of the clinical presentation, diagnostic findings and survival.

Palermo V, Stafford Johnson MJ, Sala E, Brambilla PG, Martin MW.

J Vet Cardiol. 2011 Mar;13(1):45-55. doi: 10.1016/j.jvc.2010.06.005.

18.

A retrospective study of 153 cases of undiagnosed collapse, syncope or exercise intolerance: the outcomes.

Barnett L, Martin MW, Todd J, Smith S, Cobb M.

J Small Anim Pract. 2011 Jan;52(1):26-31. doi: 10.1111/j.1748-5827.2010.01013.x.

PMID:
21175622
19.

PE2GO: program evaluation of a physical activity program in elementary schools.

Martin MW, Martin S, Rosengard P.

J Phys Act Health. 2010 Sep;7(5):677-84.

PMID:
20864765
20.

Update on lymphocyte specific kinase inhibitors: a patent survey.

Martin MW, Machacek MR.

Expert Opin Ther Pat. 2010 Nov;20(11):1573-93. doi: 10.1517/13543776.2010.517749. Epub 2010 Sep 10. Review.

PMID:
20831362
21.

Canine dilated cardiomyopathy: a retrospective study of prognostic findings in 367 clinical cases.

Martin MW, Stafford Johnson MJ, Strehlau G, King JN.

J Small Anim Pract. 2010 Aug;51(8):428-36. doi: 10.1111/j.1748-5827.2010.00966.x.

PMID:
20670255
22.

Heart rate responses to standardized trauma-related pictures in acute posttraumatic stress disorder.

Ehlers A, Suendermann O, Boellinghaus I, Vossbeck-Elsebusch A, Gamer M, Briddon E, Martin MW, Glucksman E.

Int J Psychophysiol. 2010 Oct;78(1):27-34. doi: 10.1016/j.ijpsycho.2010.04.009. Epub 2010 May 5.

23.

Healthy Maine Partnerships: policy and environmental changes.

Martin SL, Maines D, Martin MW, MacDonald PB, Polacsek M, Wigand D, Ronan L, Andrade M, Dufresne R.

Prev Chronic Dis. 2009 Apr;6(2):A63. Epub 2009 Mar 16.

24.

Discovery of alpha-amidosulfones as potent and selective agonists of CB2: synthesis, SAR, and pharmacokinetic properties.

Marx IE, DiMauro EF, Cheng A, Emkey R, Hitchcock SA, Huang L, Huang MY, Human J, Lee JH, Li X, Martin MW, White RD, Fremeau RT Jr, Patel VF.

Bioorg Med Chem Lett. 2009 Jan 1;19(1):31-5. doi: 10.1016/j.bmcl.2008.11.026. Epub 2008 Nov 13.

PMID:
19062274
25.

Canine dilated cardiomyopathy: a retrospective study of signalment, presentation and clinical findings in 369 cases.

Martin MW, Stafford Johnson MJ, Celona B.

J Small Anim Pract. 2009 Jan;50(1):23-9. doi: 10.1111/j.1748-5827.2008.00659.x. Epub 2008 Nov 13.

PMID:
19037887
26.

Discovery and optimization of a novel series of N-arylamide oxadiazoles as potent, highly selective and orally bioavailable cannabinoid receptor 2 (CB2) agonists.

Cheng Y, Albrecht BK, Brown J, Buchanan JL, Buckner WH, DiMauro EF, Emkey R, Fremeau RT Jr, Harmange JC, Hoffman BJ, Huang L, Huang M, Lee JH, Lin FF, Martin MW, Nguyen HQ, Patel VF, Tomlinson SA, White RD, Xia X, Hitchcock SA.

J Med Chem. 2008 Aug 28;51(16):5019-34. doi: 10.1021/jm800463f. Epub 2008 Aug 5.

PMID:
18680277
27.

Structural modifications of N-arylamide oxadiazoles: Identification of N-arylpiperidine oxadiazoles as potent and selective agonists of CB2.

DiMauro EF, Buchanan JL, Cheng A, Emkey R, Hitchcock SA, Huang L, Huang MY, Janosky B, Lee JH, Li X, Martin MW, Tomlinson SA, White RD, Zheng XM, Patel VF, Fremeau RT Jr.

Bioorg Med Chem Lett. 2008 Aug 1;18(15):4267-74. doi: 10.1016/j.bmcl.2008.06.096. Epub 2008 Jul 3. Erratum in: Bioorg Med Chem Lett. 2008 Sep 15;18(18):5156. Bioorg Med Chem Lett. 2009 Jan 1;19(1):284.

PMID:
18640038
28.

Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation.

Harmange JC, Weiss MM, Germain J, Polverino AJ, Borg G, Bready J, Chen D, Choquette D, Coxon A, DeMelfi T, DiPietro L, Doerr N, Estrada J, Flynn J, Graceffa RF, Harriman SP, Kaufman S, La DS, Long A, Martin MW, Neervannan S, Patel VF, Potashman M, Regal K, Roveto PM, Schrag ML, Starnes C, Tasker A, Teffera Y, Wang L, White RD, Whittington DA, Zanon R.

J Med Chem. 2008 Mar 27;51(6):1649-67. doi: 10.1021/jm701097z. Epub 2008 Mar 7.

PMID:
18324761
29.

Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.

DiMauro EF, Newcomb J, Nunes JJ, Bemis JE, Boucher C, Chai L, Chaffee SC, Deak HL, Epstein LF, Faust T, Gallant P, Gore A, Gu Y, Henkle B, Hsieh F, Huang X, Kim JL, Lee JH, Martin MW, McGowan DC, Metz D, Mohn D, Morgenstern KA, Oliveira-dos-Santos A, Patel VF, Powers D, Rose PE, Schneider S, Tomlinson SA, Tudor YY, Turci SM, Welcher AA, Zhao H, Zhu L, Zhu X.

J Med Chem. 2008 Mar 27;51(6):1681-94. doi: 10.1021/jm7010996. Epub 2008 Mar 6.

PMID:
18321037
30.

Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis.

La DS, Belzile J, Bready JV, Coxon A, DeMelfi T, Doerr N, Estrada J, Flynn JC, Flynn SR, Graceffa RF, Harriman SP, Larrow JF, Long AM, Martin MW, Morrison MJ, Patel VF, Roveto PM, Wang L, Weiss MM, Whittington DA, Teffera Y, Zhao Z, Polverino AJ, Harmange JC.

J Med Chem. 2008 Mar 27;51(6):1695-705. doi: 10.1021/jm701129j. Epub 2008 Feb 27.

PMID:
18311900
31.

Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity.

Martin MW, Newcomb J, Nunes JJ, Boucher C, Chai L, Epstein LF, Faust T, Flores S, Gallant P, Gore A, Gu Y, Hsieh F, Huang X, Kim JL, Middleton S, Morgenstern K, Oliveira-dos-Santos A, Patel VF, Powers D, Rose P, Tudor Y, Turci SM, Welcher AA, Zack D, Zhao H, Zhu L, Zhu X, Ghiron C, Ermann M, Johnston D, Saluste CG.

J Med Chem. 2008 Mar 27;51(6):1637-48. doi: 10.1021/jm701095m. Epub 2008 Feb 16.

PMID:
18278858
32.
33.

Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: development of an expedient and divergent synthetic route and preliminary SAR.

DiMauro EF, Newcomb J, Nunes JJ, Bemis JE, Boucher C, Buchanan JL, Buckner WH, Cheng A, Faust T, Hsieh F, Huang X, Lee JH, Marshall TL, Martin MW, McGowan DC, Schneider S, Turci SM, White RD, Zhu X.

Bioorg Med Chem Lett. 2007 Apr 15;17(8):2305-9. Epub 2007 Jan 25. Erratum in: Bioorg Med Chem Lett. 2007 Sep 15;17(18):5280.

PMID:
17280833
34.

Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties.

Martin MW, Newcomb J, Nunes JJ, Bemis JE, McGowan DC, White RD, Buchanan JL, DiMauro EF, Boucher C, Faust T, Hsieh F, Huang X, Lee JH, Schneider S, Turci SM, Zhu X.

Bioorg Med Chem Lett. 2007 Apr 15;17(8):2299-304. Epub 2007 Jan 24. Erratum in: Bioorg Med Chem Lett. 2007 Sep 15;17(18):5279.

PMID:
17276681
35.

Successful medical treatment of 15 dogs with pyothorax.

Johnson MS, Martin MW.

J Small Anim Pract. 2007 Jan;48(1):12-6.

PMID:
17212743
36.

Results of pacemaker implantation in 104 dogs.

Johnson MS, Martin MW, Henley W.

J Small Anim Pract. 2007 Jan;48(1):4-11.

PMID:
17212742
37.

Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity.

DiMauro EF, Newcomb J, Nunes JJ, Bemis JE, Boucher C, Buchanan JL, Buckner WH, Cee VJ, Chai L, Deak HL, Epstein LF, Faust T, Gallant P, Geuns-Meyer SD, Gore A, Gu Y, Henkle B, Hodous BL, Hsieh F, Huang X, Kim JL, Lee JH, Martin MW, Masse CE, McGowan DC, Metz D, Mohn D, Morgenstern KA, Oliveira-dos-Santos A, Patel VF, Powers D, Rose PE, Schneider S, Tomlinson SA, Tudor YY, Turci SM, Welcher AA, White RD, Zhao H, Zhu L, Zhu X.

J Med Chem. 2006 Sep 21;49(19):5671-86.

PMID:
16970394
38.
39.

Moral creativity in science and engineering.

Martin MW.

Sci Eng Ethics. 2006 Jul;12(3):421-33.

PMID:
16909147
40.

Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity.

Martin MW, Newcomb J, Nunes JJ, McGowan DC, Armistead DM, Boucher C, Buchanan JL, Buckner W, Chai L, Elbaum D, Epstein LF, Faust T, Flynn S, Gallant P, Gore A, Gu Y, Hsieh F, Huang X, Lee JH, Metz D, Middleton S, Mohn D, Morgenstern K, Morrison MJ, Novak PM, Oliveira-dos-Santos A, Powers D, Rose P, Schneider S, Sell S, Tudor Y, Turci SM, Welcher AA, White RD, Zack D, Zhao H, Zhu L, Zhu X, Ghiron C, Amouzegh P, Ermann M, Jenkins J, Johnston D, Napier S, Power E.

J Med Chem. 2006 Aug 10;49(16):4981-91.

PMID:
16884310
41.

Idiopathic pericarditis in dogs: no evidence for an immune-mediated aetiology.

Martin MW, Green MJ, Stafford Johnson MJ, Day MJ.

J Small Anim Pract. 2006 Jul;47(7):387-91.

PMID:
16842275
43.

TV viewing habits and body mass index among South Carolina Head Start children.

Levin S, Martin MW, Riner WF.

Ethn Dis. 2004 Summer;14(3):336-9.

PMID:
15328934
44.

Explaining wrongdoing in professions.

Martin MW.

J Soc Philos. 1999 Summer;30(2):236-50. No abstract available.

PMID:
15072069
45.

[3H]Ethynylbicycloorthobenzoate ([3H]EBOB) binding in recombinant GABAA receptors.

Yagle MA, Martin MW, de Fiebre CM, de Fiebre NC, Drewe JA, Dillon GH.

Neurotoxicology. 2003 Dec;24(6):817-24.

PMID:
14637376
46.

Assessment of a pilot video's effect on physical activity and heart health for young children.

Levin S, Martin MW, McKenzie TL, DeLouise AC.

Fam Community Health. 2002 Oct;25(3):10-7.

PMID:
12802138
47.

Treatment of congestive heart failure a neuroendocrine disorder.

Martin MW.

J Small Anim Pract. 2003 Apr;44(4):154-60. Review.

PMID:
12703866
48.

Septic fibrinous pericarditis in a cocker spaniel.

Stafford Johnson JM, Martin MW, Stidworthy MF.

J Small Anim Pract. 2003 Mar;44(3):117-20.

PMID:
12653326
49.

Personal meaning and ethics in engineering.

Martin MW.

Sci Eng Ethics. 2002 Oct;8(4):545-60. Review.

PMID:
12501724
50.

Immunohistochemical characterisation of the lesions of canine idiopathic pericarditis.

Day MJ, Martin MW.

J Small Anim Pract. 2002 Sep;43(9):382-7.

PMID:
12238502

Supplemental Content

Loading ...
Support Center