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Items: 1 to 50 of 112

1.

microRNA-181a-5p antisense oligonucleotides attenuate osteoarthritis in facet and knee joints.

Nakamura A, Rampersaud YR, Nakamura S, Sharma A, Zeng F, Rossomacha E, Ali SA, Krawetz R, Haroon N, Perruccio AV, Mahomed NN, Gandhi R, Rockel JS, Kapoor M.

Ann Rheum Dis. 2018 Oct 4. pii: annrheumdis-2018-213629. doi: 10.1136/annrheumdis-2018-213629. [Epub ahead of print]

PMID:
30287418
2.

Presurgery osteoarthritis severity over 10 years in 2 Ontario prospective total knee replacement cohorts: a cohort study.

Davis AM, Ibrahim S, Hogg-Johnson S, Beaton DE, Chesworth BM, Gandhi R, Mahomed NN, Perruccio AV, Rajgopal V, Wong R, Waddell JP.

CMAJ Open. 2018 Jul 19;6(3):E269-E275. doi: 10.9778/cmajo.20170164. Print 2018 Jul-Sep.

3.

Factors associated with the orthopaedic surgeon's decision to recommend total joint replacement in hip and knee osteoarthritis: an international cross-sectional study of 1905 patients.

Huynh C, Puyraimond-Zemmour D, Maillefert JF, Conaghan PG, Davis AM, Gunther KP, Hawker G, Hochberg MC, Kloppenburg M, Lim K, Lohmander LS, Mahomed NN, March L, Pavelka K, Punzi L, Roos EM, Sanchez-Riera L, Singh JA, Suarez-Almazor ME, Dougados M, Gossec L.

Osteoarthritis Cartilage. 2018 Oct;26(10):1311-1318. doi: 10.1016/j.joca.2018.06.013. Epub 2018 Jul 11.

PMID:
30017727
4.

Neuropathic pain in end-stage hip and knee osteoarthritis: differential associations with patient-reported pain at rest and pain on activity.

Power JD, Perruccio AV, Gandhi R, Veillette C, Davey JR, Syed K, Mahomed NN, Rampersaud YR.

Osteoarthritis Cartilage. 2018 Mar;26(3):363-369. doi: 10.1016/j.joca.2018.01.002. Epub 2018 Jan 9.

PMID:
29326061
5.

Understanding the Relationship Between 3-Month and 2-Year Pain and Function Scores After Total Knee Arthroplasty for Osteoarthritis.

Gandhi R, Mahomed NN, Cram P, Perruccio AV.

J Arthroplasty. 2018 May;33(5):1368-1372. doi: 10.1016/j.arth.2017.11.051. Epub 2017 Dec 6.

PMID:
29254828
6.

High-fat diet-induced acceleration of osteoarthritis is associated with a distinct and sustained plasma metabolite signature.

Datta P, Zhang Y, Parousis A, Sharma A, Rossomacha E, Endisha H, Wu B, Kacprzak I, Mahomed NN, Gandhi R, Rockel JS, Kapoor M.

Sci Rep. 2017 Aug 15;7(1):8205. doi: 10.1038/s41598-017-07963-6.

7.

Systemic inflammation and painful joint burden in osteoarthritis: a matter of sex?

Perruccio AV, Chandran V, Power JD, Kapoor M, Mahomed NN, Gandhi R.

Osteoarthritis Cartilage. 2017 Jan;25(1):53-59. doi: 10.1016/j.joca.2016.08.001. Epub 2016 Aug 19.

8.

Identification of synovial fluid microRNA signature in knee osteoarthritis: differentiating early- and late-stage knee osteoarthritis.

Li YH, Tavallaee G, Tokar T, Nakamura A, Sundararajan K, Weston A, Sharma A, Mahomed NN, Gandhi R, Jurisica I, Kapoor M.

Osteoarthritis Cartilage. 2016 Sep;24(9):1577-86. doi: 10.1016/j.joca.2016.04.019. Epub 2016 Apr 30.

9.

Cross-Sectional Contrast Between Individuals With Foot/Ankle vs Knee Osteoarthritis for Obesity and Low Education on Health-Related Quality of Life.

Perruccio AV, Gandhi R, Lau JT, Syed KA, Mahomed NN, Rampersaud YR.

Foot Ankle Int. 2016 Jan;37(1):24-32. doi: 10.1177/1071100715600282. Epub 2015 Sep 3.

PMID:
26337948
10.

Depression and the Overall Burden of Painful Joints: An Examination among Individuals Undergoing Hip and Knee Replacement for Osteoarthritis.

Gandhi R, Zywiel MG, Mahomed NN, Perruccio AV.

Arthritis. 2015;2015:327161. doi: 10.1155/2015/327161. Epub 2015 Mar 11.

11.

A comparison of obesity related adipokine concentrations in knee and shoulder osteoarthritis patients.

Gandhi R, Kapoor M, Mahomed NN, Perruccio AV.

Obes Res Clin Pract. 2015 Jul-Aug;9(4):420-3. doi: 10.1016/j.orcp.2015.02.003. Epub 2015 Feb 21.

PMID:
25716299
12.

PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage.

Vasheghani F, Zhang Y, Li YH, Blati M, Fahmi H, Lussier B, Roughley P, Lagares D, Endisha H, Saffar B, Lajeunesse D, Marshall WK, Rampersaud YR, Mahomed NN, Gandhi R, Pelletier JP, Martel-Pelletier J, Kapoor M.

Ann Rheum Dis. 2015 Mar;74(3):569-78. doi: 10.1136/annrheumdis-2014-205743. Epub 2015 Jan 8.

13.

Stem cell therapy for the treatment of early stage avascular necrosis of the femoral head: a systematic review.

Lau RL, Perruccio AV, Evans HM, Mahomed SR, Mahomed NN, Gandhi R.

BMC Musculoskelet Disord. 2014 May 16;15:156. doi: 10.1186/1471-2474-15-156. Review.

14.

Associations between patient expectations of joint arthroplasty surgery and pre- and post-operative clinical status.

Dyck BA, Zywiel MG, Mahomed A, Gandhi R, Perruccio AV, Mahomed NN.

Expert Rev Med Devices. 2014 Jul;11(4):403-15. doi: 10.1586/17434440.2014.916208. Epub 2014 May 3. Review.

PMID:
24793876
15.

Obesity-related adipokines predict patient-reported shoulder pain.

Gandhi R, Perruccio AV, Rizek R, Dessouki O, Evans HM, Mahomed NN.

Obes Facts. 2013;6(6):536-41. doi: 10.1159/000357230. Epub 2013 Dec 6.

16.

Plasma adipokine levels and their association with overall burden of painful joints among individuals with hip and knee osteoarthritis.

Perruccio AV, Mahomed NN, Chandran V, Gandhi R.

J Rheumatol. 2014 Feb;41(2):334-7. doi: 10.3899/jrheum.130709. Epub 2013 Dec 15.

PMID:
24334649
17.

Comparative outcomes and cost-utility after surgical treatment of focal lumbar spinal stenosis compared with osteoarthritis of the hip or knee--part 1: long-term change in health-related quality of life.

Rampersaud YR, Lewis SJ, Davey JR, Gandhi R, Mahomed NN.

Spine J. 2014 Feb 1;14(2):234-43. doi: 10.1016/j.spinee.2013.12.010. Epub 2013 Dec 8.

18.

Comparative outcomes and cost-utility following surgical treatment of focal lumbar spinal stenosis compared with osteoarthritis of the hip or knee: part 2--estimated lifetime incremental cost-utility ratios.

Rampersaud YR, Tso P, Walker KR, Lewis SJ, Davey JR, Mahomed NN, Coyte PC.

Spine J. 2014 Feb 1;14(2):244-54. doi: 10.1016/j.spinee.2013.11.011. Epub 2013 Nov 12.

PMID:
24239803
19.

Surgical management of hip osteoarthritis.

Gandhi R, Perruccio AV, Mahomed NN.

CMAJ. 2014 Mar 18;186(5):347-55. doi: 10.1503/cmaj.121584. Epub 2013 Oct 21. Review. No abstract available.

20.

Surgery or consultation: a population-based cohort study of use of orthopaedic surgeon services.

Badley EM, Canizares M, MacKay C, Mahomed NN, Davis AM.

PLoS One. 2013 Jun 4;8(6):e65560. doi: 10.1371/journal.pone.0065560. Print 2013.

21.

Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.

Gandhi R, Evans HM, Mahomed SR, Mahomed NN.

BMC Res Notes. 2013 May 7;6:184. doi: 10.1186/1756-0500-6-184.

22.

Measuring expectations in orthopaedic surgery: a systematic review.

Zywiel MG, Mahomed A, Gandhi R, Perruccio AV, Mahomed NN.

Clin Orthop Relat Res. 2013 Nov;471(11):3446-56. doi: 10.1007/s11999-013-3013-8. Review.

23.

The importance of perceived helplessness and emotional health in understanding the relationship among pain, function, and satisfaction following revision knee replacement surgery.

Venkataramanan V, Gignac MA, Dunbar M, Garbuz D, Gollish J, Gross A, Hedden D, MacDonald SJ, Mahomed NN, Schemitsch E, Davis AM.

Osteoarthritis Cartilage. 2013 Jul;21(7):911-7. doi: 10.1016/j.joca.2013.04.005. Epub 2013 Apr 18.

24.

Predicting return to work following treatment of chronic pain disorder.

Hamer H, Gandhi R, Wong S, Mahomed NN.

Occup Med (Lond). 2013 Jun;63(4):253-9. doi: 10.1093/occmed/kqt019. Epub 2013 Mar 14.

PMID:
23503298
25.

Influence of patients' gender on informed decision making regarding total knee arthroplasty.

Borkhoff CM, Hawker GA, Kreder HJ, Glazier RH, Mahomed NN, Wright JG.

Arthritis Care Res (Hoboken). 2013 Aug;65(8):1281-90. doi: 10.1002/acr.21970.

26.

The role of surgeon volume on patient outcome in total knee arthroplasty: a systematic review of the literature.

Lau RL, Perruccio AV, Gandhi R, Mahomed NN.

BMC Musculoskelet Disord. 2012 Dec 14;13:250. doi: 10.1186/1471-2474-13-250. Review.

28.

Inflammatory predictors of ongoing pain 2 years following knee replacement surgery.

Gandhi R, Santone D, Takahashi M, Dessouki O, Mahomed NN.

Knee. 2013 Oct;20(5):316-8. doi: 10.1016/j.knee.2012.10.015. Epub 2012 Nov 14.

PMID:
23157967
29.

Twelve-year risk of revision after primary total hip replacement in the U.S. Medicare population.

Katz JN, Wright EA, Wright J, Malchau H, Mahomed NN, Stedman M, Baron JA, Losina E.

J Bone Joint Surg Am. 2012 Oct 17;94(20):1825-32. doi: 10.2106/JBJS.K.00569.

30.

Obesity-related adipokines and shoulder osteoarthritis.

Gandhi R, Takahashi M, Rizek R, Dessouki O, Mahomed NN.

J Rheumatol. 2012 Oct;39(10):2046-8. doi: 10.3899/jrheum.111339. No abstract available.

PMID:
23028030
31.

Multiple joint involvement in total knee replacement for osteoarthritis: Effects on patient-reported outcomes.

Perruccio AV, Power JD, Evans HM, Mahomed SR, Gandhi R, Mahomed NN, Davis AM.

Arthritis Care Res (Hoboken). 2012 Jun;64(6):838-46. doi: 10.1002/acr.21629. Epub 2012 May 8.

32.

Comparison of arthroplasty trial publications after registration in ClinicalTrials.gov.

Smith HN, Bhandari M, Mahomed NN, Jan M, Gandhi R.

J Arthroplasty. 2012 Aug;27(7):1283-8. doi: 10.1016/j.arth.2011.11.005. Epub 2012 Jan 5.

PMID:
22226609
33.

A pilot study of computed tomography-detected asymptomatic pulmonary filling defects after hip and knee arthroplasties.

Gandhi R, Salonen D, Geerts WH, Khanna M, McSweeney S, Mahomed NN.

J Arthroplasty. 2012 May;27(5):730-5. doi: 10.1016/j.arth.2011.10.019. Epub 2011 Dec 16.

PMID:
22177790
34.

Comparison of published orthopaedic trauma trials following registration in Clinicaltrials.gov.

Gandhi R, Jan M, Smith HN, Mahomed NN, Bhandari M.

BMC Musculoskelet Disord. 2011 Dec 7;12:278. doi: 10.1186/1471-2474-12-278.

35.

The trajectory of recovery and the inter-relationships of symptoms, activity and participation in the first year following total hip and knee replacement.

Davis AM, Perruccio AV, Ibrahim S, Hogg-Johnson S, Wong R, Streiner DL, Beaton DE, Côté P, Gignac MA, Flannery J, Schemitsch E, Mahomed NN, Badley EM.

Osteoarthritis Cartilage. 2011 Dec;19(12):1413-21. doi: 10.1016/j.joca.2011.08.007. Epub 2011 Aug 18.

36.

OARSI/OMERACT initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis. An OMERACT 10 Special Interest Group.

Gossec L, Paternotte S, Bingham CO 3rd, Clegg DO, Coste P, Conaghan PG, Davis AM, Giacovelli G, Gunther KP, Hawker G, Hochberg MC, Jordan JM, Katz JN, Kloppenburg M, Lanzarotti A, Lim K, Lohmander LS, Mahomed NN, Maillefert JF, Manno RL, March LM, Mazzuca SA, Pavelka K, Punzi L, Roos EM, Rovati LC, Shi H, Singh JA, Suarez-Almazor ME, Tajana-Messi E, Dougados M; OARSI-OMERACT Task Force Total Articular Replacement as Outcome Measure in OA.

J Rheumatol. 2011 Aug;38(8):1765-9. doi: 10.3899/jrheum.110403.

37.

Microarray analysis of the infrapatellar fat pad in knee osteoarthritis: relationship with joint inflammation.

Gandhi R, Takahashi M, Virtanen C, Syed K, Davey JR, Mahomed NN.

J Rheumatol. 2011 Sep;38(9):1966-72. doi: 10.3899/jrheum.101302. Epub 2011 Jul 15.

PMID:
21765106
38.

Who’s in the driver's seat? The influence of patient and physician enthusiasm on regional variation in degenerative lumbar spinal surgery: a population-based study.

Bederman SS, Coyte PC, Kreder HJ, Mahomed NN, McIsaac WJ, Wright JG.

Spine (Phila Pa 1976). 2011 Mar 15;36(6):481-489.

PMID:
21488247
39.

Meta-analysis and systematic review of clinical outcomes comparing mobile bearing and fixed bearing total knee arthroplasty.

Smith H, Jan M, Mahomed NN, Davey JR, Gandhi R.

J Arthroplasty. 2011 Dec;26(8):1205-13. doi: 10.1016/j.arth.2010.12.017. Epub 2011 Feb 4. Review.

PMID:
21295940
40.

Risk of wound infection is greater after skin closure with staples than with sutures in orthopaedic surgery.

Syed KA, Gandhi R, Davey JR, Mahomed NN.

J Bone Joint Surg Am. 2010 Nov 17;92(16):2732. doi: 10.2106/JBJS.9216.ebo818. No abstract available.

PMID:
21084584
41.

Topical application of tranexamic acid reduces postoperative blood loss in total knee arthroplasty: a randomized, controlled trial.

Wong J, Abrishami A, El Beheiry H, Mahomed NN, Roderick Davey J, Gandhi R, Syed KA, Muhammad Ovais Hasan S, De Silva Y, Chung F.

J Bone Joint Surg Am. 2010 Nov 3;92(15):2503-13. doi: 10.2106/JBJS.I.01518.

PMID:
21048170
42.

The role of pain and functional impairment in the decision to recommend total joint replacement in hip and knee osteoarthritis: an international cross-sectional study of 1909 patients. Report of the OARSI-OMERACT Task Force on total joint replacement.

Gossec L, Paternotte S, Maillefert JF, Combescure C, Conaghan PG, Davis AM, Gunther KP, Hawker G, Hochberg M, Katz JN, Kloppenburg M, Lim K, Lohmander LS, Mahomed NN, March L, Pavelka K, Punzi L, Roos EM, Sanchez-Riera L, Singh JA, Suarez-Almazor ME, Dougados M; OARSI-OMERACT Task Force "total articular replacement as outcome measure in OA".

Osteoarthritis Cartilage. 2011 Feb;19(2):147-54. doi: 10.1016/j.joca.2010.10.025. Epub 2010 Oct 31.

43.

Predicting the longer-term outcomes of total hip replacement.

Gandhi R, Dhotar H, Davey JR, Mahomed NN.

J Rheumatol. 2010 Dec;37(12):2573-7. doi: 10.3899/jrheum.100149. Epub 2010 Sep 1.

PMID:
20810497
44.

Quantifying the pain experience in hip and knee osteoarthritis.

Gandhi R, Tsvetkov D, Dhottar H, Davey JR, Mahomed NN.

Pain Res Manag. 2010 Jul-Aug;15(4):224-8.

45.

Referral practices for spinal surgery are poorly predicted by clinical guidelines and opinions of primary care physicians.

Bederman SS, McIsaac WJ, Coyte PC, Kreder HJ, Mahomed NN, Wright JG.

Med Care. 2010 Sep;48(9):852-8. doi: 10.1097/MLR.0b013e3181e3588b.

PMID:
20706169
46.

Incorrect use of the student t test in randomized trials of bilateral hip and knee arthroplasty patients.

Gandhi R, Smith HN, Mahomed NN, Rizek R, Bhandari M.

J Arthroplasty. 2011 Aug;26(5):811-6. doi: 10.1016/j.arth.2010.06.007. Epub 2010 Jul 20. Review.

PMID:
20663639
47.

Metabolic syndrome and the functional outcomes of hip and knee arthroplasty.

Gandhi R, Razak F, Davey JR, Mahomed NN.

J Rheumatol. 2010 Sep;37(9):1917-22. doi: 10.3899/jrheum.091242. Epub 2010 Jul 15.

PMID:
20634242
48.

Decreasing medical complications for total knee arthroplasty: effect of critical pathways on outcomes.

Husni ME, Losina E, Fossel AH, Solomon DH, Mahomed NN, Katz JN.

BMC Musculoskelet Disord. 2010 Jul 14;11:160. doi: 10.1186/1471-2474-11-160.

49.

Variability in physician opinions about the indications for knee arthroplasty.

Toronto Arthroplasty Research Group Writing Committee, Wright JG, Hawker GA, Hudak PL, Croxford R, Glazier RH, Mahomed NN, Kreder HJ, Coyte PC.

J Arthroplasty. 2011 Jun;26(4):569-575.e1. doi: 10.1016/j.arth.2010.04.028. Epub 2010 Jul 1.

PMID:
20580197
50.

Rehabilitation services following total joint replacement: a qualitative analysis of key processes and structures to decrease length of stay and increase surgical volumes in Ontario, Canada.

Fancott C, Jaglal S, Quan V, Berg K, Cott CA, Davis A, Flannery J, Hawker G, Landry MD, Mahomed NN, Badley E.

J Eval Clin Pract. 2010 Aug;16(4):724-30. doi: 10.1111/j.1365-2753.2009.01185.x. Epub 2010 Jun 10.

PMID:
20545803

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