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Items: 1 to 50 of 52

1.

Influenza binds phosphorylated glycans from human lung.

Byrd-Leotis L, Jia N, Dutta S, Trost JF, Gao C, Cummings SF, Braulke T, Müller-Loennies S, Heimburg-Molinaro J, Steinhauer DA, Cummings RD.

Sci Adv. 2019 Feb 13;5(2):eaav2554. doi: 10.1126/sciadv.aav2554. eCollection 2019 Feb.

2.

Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.

Haji-Ghassemi O, Müller-Loennies S, Brooks CL, MacKenzie CR, Caveney N, Van Petegem F, Brade L, Kosma P, Brade H, Evans SV.

Biochemistry. 2019 Feb 12;58(6):714-726. doi: 10.1021/acs.biochem.8b00318. Epub 2019 Jan 10.

PMID:
30571096
3.

Lysosomal Proteome and Secretome Analysis Identifies Missorted Enzymes and Their Nondegraded Substrates in Mucolipidosis III Mouse Cells.

Di Lorenzo G, Velho RV, Winter D, Thelen M, Ahmadi S, Schweizer M, De Pace R, Cornils K, Yorgan TA, Grüb S, Hermans-Borgmeyer I, Schinke T, Müller-Loennies S, Braulke T, Pohl S.

Mol Cell Proteomics. 2018 Aug;17(8):1612-1626. doi: 10.1074/mcp.RA118.000720. Epub 2018 May 17.

4.

Polyspecificity of Anti-lipid A Antibodies and Its Relevance to the Development of Autoimmunity.

Haji-Ghassemi O, Gagnon SML, Müller-Loennies S, Evans SV.

Adv Exp Med Biol. 2017;966:181-202. doi: 10.1007/5584_2017_94. Review.

PMID:
28887790
5.

The Combining Sites of Anti-lipid A Antibodies Reveal a Widely Utilized Motif Specific for Negatively Charged Groups.

Haji-Ghassemi O, Müller-Loennies S, Rodriguez T, Brade L, Grimmecke HD, Brade H, Evans SV.

J Biol Chem. 2016 May 6;291(19):10104-18. doi: 10.1074/jbc.M115.712448. Epub 2016 Mar 1.

6.

Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishes N-glycan phosphorylation in a branch-specific manner†.

Blackler RJ, Evans DW, Smith DF, Cummings RD, Brooks CL, Braulke T, Liu X, Evans SV, Müller-Loennies S.

Glycobiology. 2016 Feb;26(2):181-92. doi: 10.1093/glycob/cwv093. Epub 2015 Oct 26.

7.

Structural Basis for Antibody Recognition of Lipid A: INSIGHTS TO POLYSPECIFICITY TOWARD SINGLE-STRANDED DNA.

Haji-Ghassemi O, Müller-Loennies S, Rodriguez T, Brade L, Kosma P, Brade H, Evans SV.

J Biol Chem. 2015 Aug 7;290(32):19629-40. doi: 10.1074/jbc.M115.657874. Epub 2015 Jun 17.

8.
9.

Groove-type recognition of chlamydiaceae-specific lipopolysaccharide antigen by a family of antibodies possessing an unusual variable heavy chain N-linked glycan.

Haji-Ghassemi O, Müller-Loennies S, Saldova R, Muniyappa M, Brade L, Rudd PM, Harvey DJ, Kosma P, Brade H, Evans SV.

J Biol Chem. 2014 Jun 13;289(24):16644-61. doi: 10.1074/jbc.M113.528224. Epub 2014 Mar 28.

10.

Evaluation of butyrate-induced production of a mannose-6-phosphorylated therapeutic enzyme using parallel bioreactors.

Madhavarao CN, Agarabi CD, Wong L, Müller-Loennies S, Braulke T, Khan M, Anderson H, Johnson GR.

Biotechnol Appl Biochem. 2014 Mar-Apr;61(2):184-92. doi: 10.1002/bab.1151. Epub 2014 Feb 20.

PMID:
24033810
11.

Molecular and structural basis of inner core lipopolysaccharide alterations in Escherichia coli: incorporation of glucuronic acid and phosphoethanolamine in the heptose region.

Klein G, Müller-Loennies S, Lindner B, Kobylak N, Brade H, Raina S.

J Biol Chem. 2013 Mar 22;288(12):8111-27. doi: 10.1074/jbc.M112.445981. Epub 2013 Jan 31.

12.

Exploring the cross-reactivity of S25-2: complex with a 5,6-dehydro-Kdo disaccharide.

Brooks CL, Wimmer K, Kosma P, Müller-Loennies S, Brade L, Brade H, Evans SV.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jan 1;69(Pt 1):2-5. doi: 10.1107/S1744309112047422. Epub 2012 Dec 25.

13.

Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS.

Gomery K, Müller-Loennies S, Brooks CL, Brade L, Kosma P, Di Padova F, Brade H, Evans SV.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20877-82. doi: 10.1073/pnas.1209253109. Epub 2012 Nov 26.

14.

Mannose 6 dephosphorylation of lysosomal proteins mediated by acid phosphatases Acp2 and Acp5.

Makrypidi G, Damme M, Müller-Loennies S, Trusch M, Schmidt B, Schlüter H, Heeren J, Lübke T, Saftig P, Braulke T.

Mol Cell Biol. 2012 Feb;32(4):774-82. doi: 10.1128/MCB.06195-11. Epub 2011 Dec 12.

15.

Immunization with an anti-idiotypic antibody against the broadly lipopolysaccharide-reactive antibody WN1 222-5 induces Escherichia coli R3-core-type specific antibodies in rabbits.

Brade L, Heine H, Raina S, Klein G, Di Padova F, Brade H, Müller-Loennies S.

Innate Immun. 2012 Apr;18(2):279-93. doi: 10.1177/1753425911401055. Epub 2011 Aug 15.

PMID:
21844130
16.

Structural insights into parallel strategies for germline antibody recognition of lipopolysaccharide from Chlamydia.

Evans DW, Müller-Loennies S, Brooks CL, Brade L, Kosma P, Brade H, Evans SV.

Glycobiology. 2011 Aug;21(8):1049-59. doi: 10.1093/glycob/cwr041. Epub 2011 May 4.

PMID:
21543444
17.

A common NH53K mutation in the combining site of antibodies raised against chlamydial LPS glycoconjugates significantly increases avidity.

Blackler RJ, Müller-Loennies S, Brooks CL, Evans DW, Brade L, Kosma P, Brade H, Evans SV.

Biochemistry. 2011 Apr 26;50(16):3357-68. doi: 10.1021/bi101886v. Epub 2011 Apr 1.

PMID:
21405106
18.

Proteolytic processing of the gamma-subunit is associated with the failure to form GlcNAc-1-phosphotransferase complexes and mannose 6-phosphate residues on lysosomal enzymes in human macrophages.

Pohl S, Tiede S, Marschner K, Encarnação M, Castrichini M, Kollmann K, Muschol N, Ullrich K, Müller-Loennies S, Braulke T.

J Biol Chem. 2010 Jul 30;285(31):23936-44. doi: 10.1074/jbc.M110.129684. Epub 2010 May 19.

19.

A novel single-chain antibody fragment for detection of mannose 6-phosphate-containing proteins: application in mucolipidosis type II patients and mice.

Müller-Loennies S, Galliciotti G, Kollmann K, Glatzel M, Braulke T.

Am J Pathol. 2010 Jul;177(1):240-7. doi: 10.2353/ajpath.2010.090954. Epub 2010 May 14.

20.

Synthesis of a neoglycoconjugate containing a Chlamydophila psittaci-specific branched Kdo trisaccharide epitope.

Kosma P, Hofinger A, Müller-Loennies S, Brade H.

Carbohydr Res. 2010 Mar 30;345(5):704-8. doi: 10.1016/j.carres.2009.12.015. Epub 2009 Dec 21.

PMID:
20116048
21.

Antiserum against Raoultella terrigena ATCC 33257 identifies a large number of Raoultella and Klebsiella clinical isolates as serotype O12.

Mertens K, Müller-Loennies S, Stengel P, Podschun R, Hansen DS, Mamat U.

Innate Immun. 2010 Dec;16(6):366-80. doi: 10.1177/1753425909350057. Epub 2010 Jan 6.

PMID:
20053705
22.

Loss of N-acetylglucosamine-1-phosphotransferase gamma subunit due to intronic mutation in GNPTG causes mucolipidosis type III gamma: Implications for molecular and cellular diagnostics.

Pohl S, Encarnacão M, Castrichini M, Müller-Loennies S, Muschol N, Braulke T.

Am J Med Genet A. 2010 Jan;152A(1):124-32. doi: 10.1002/ajmg.a.33170.

PMID:
20034096
23.

Analysis of cross-reactive and specific anti-carbohydrate antibodies against lipopolysaccharide from Chlamydophila psittaci.

Gerstenbruch S, Brooks CL, Kosma P, Brade L, Mackenzie CR, Evans SV, Brade H, Müller-Loennies S.

Glycobiology. 2010 Jan;20(4):461-72. doi: 10.1093/glycob/cwp198. Epub 2009 Dec 18.

24.

Antibodies raised against chlamydial lipopolysaccharide antigens reveal convergence in germline gene usage and differential epitope recognition.

Brooks CL, Müller-Loennies S, Borisova SN, Brade L, Kosma P, Hirama T, Mackenzie CR, Brade H, Evans SV.

Biochemistry. 2010 Jan 26;49(3):570-81. doi: 10.1021/bi9011308.

25.

Mannose phosphorylation in health and disease.

Kollmann K, Pohl S, Marschner K, Encarnação M, Sakwa I, Tiede S, Poorthuis BJ, Lübke T, Müller-Loennies S, Storch S, Braulke T.

Eur J Cell Biol. 2010 Jan;89(1):117-23. doi: 10.1016/j.ejcb.2009.10.008. Epub 2009 Nov 28. Review.

PMID:
19945768
26.

Site-specific analysis of N-linked oligosaccharides of recombinant lysosomal arylsulfatase A produced in different cell lines.

Schröder S, Matthes F, Hyden P, Andersson C, Fogh J, Müller-Loennies S, Braulke T, Gieselmann V, Matzner U.

Glycobiology. 2010 Feb;20(2):248-59. doi: 10.1093/glycob/cwp171. Epub 2009 Oct 28.

PMID:
19864504
27.

The role of CDR H3 in antibody recognition of a synthetic analog of a lipopolysaccharide antigen.

Brooks CL, Blackler RJ, Sixta G, Kosma P, Müller-Loennies S, Brade L, Hirama T, MacKenzie CR, Brade H, Evans SV.

Glycobiology. 2010 Feb;20(2):138-47. doi: 10.1093/glycob/cwp150. Epub 2009 Sep 18.

PMID:
19767317
28.
29.

Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments.

Brooks CL, Blackler RJ, Gerstenbruch S, Kosma P, Müller-Loennies S, Brade H, Evans SV.

Acta Crystallogr D Biol Crystallogr. 2008 Dec;64(Pt 12):1250-8. doi: 10.1107/S0907444908033453. Epub 2008 Nov 18.

PMID:
19018101
30.

Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes.

Brooks CL, Müller-Loennies S, Brade L, Kosma P, Hirama T, MacKenzie CR, Brade H, Evans SV.

J Mol Biol. 2008 Mar 21;377(2):450-68. doi: 10.1016/j.jmb.2008.01.018. Epub 2008 Jan 16.

PMID:
18272175
31.

Recognition of heptoses and the inner core of bacterial lipopolysaccharides by surfactant protein d.

Wang H, Head J, Kosma P, Brade H, Müller-Loennies S, Sheikh S, McDonald B, Smith K, Cafarella T, Seaton B, Crouch E.

Biochemistry. 2008 Jan 15;47(2):710-20. Epub 2007 Dec 20.

PMID:
18092821
32.

Neutralizing and cross-reactive antibodies against enterobacterial lipopolysaccharide.

Müller-Loennies S, Brade L, Brade H.

Int J Med Microbiol. 2007 Sep;297(5):321-40. Epub 2007 Jun 1. Review.

PMID:
17544324
33.
34.
35.

Identification of a cross-reactive epitope widely present in lipopolysaccharide from enterobacteria and recognized by the cross-protective monoclonal antibody WN1 222-5.

Muller-Loennies S, Brade L, MacKenzie CR, Di Padova FE, Brade H.

J Biol Chem. 2003 Jul 11;278(28):25618-27. Epub 2003 Apr 25.

36.
37.
38.

A novel strategy for the synthesis of neoglycoconjugates from deacylated deep rough lipopolysaccharides.

Müller-Loennies S, Grimmecke D, Brade L, Lindner B, Kosma P, Brade H.

J Endotoxin Res. 2002;8(4):295-305.

PMID:
12230919
39.
41.

Characterization of high affinity monoclonal antibodies specific for chlamydial lipopolysaccharide.

Müller-Loennies S, MacKenzie CR, Patenaude SI, Evans SV, Kosma P, Brade H, Brade L, Narang S.

Glycobiology. 2000 Feb;10(2):121-30.

PMID:
10642603
42.

The dual role of lipopolysaccharide as effector and target molecule.

Wiese A, Brandenburg K, Ulmer AJ, Seydel U, Müller-Loennies S.

Biol Chem. 1999 Jul-Aug;380(7-8):767-84. Review.

PMID:
10494826
43.
44.

Isolation and structural analysis of phosphorylated oligosaccharides obtained from Escherichia coli J-5 lipopolysaccharide.

Müller-Loennies S, Holst O, Lindner B, Brade H.

Eur J Biochem. 1999 Feb;260(1):235-49.

45.

What we know and don't know about the chemical and physical structure of lipopolysaccharide in relation to biological activity.

Müller-Loennies S, Zähringer U, Seydel U, Kusumoto S, Ulmer AJ, Rietschel ET.

Prog Clin Biol Res. 1998;397:51-72. Review. No abstract available.

PMID:
9575547
47.

Structural investigation of the lipopolysaccharide from Acinetobacter haemolyticus strain NCTC 10305 (ATCC 17906, DNA group 4).

Vinogradov EV, Müller-Loennies S, Petersen BO, Meshkov S, Thomas-Oates JE, Holst O, Brade H.

Eur J Biochem. 1997 Jul 1;247(1):82-90.

48.

Regarding galactofuranose-containing glycoconjugates.

Bock K, Müller-Loennies S.

Glycobiology. 1996 Jan;6(1):3. No abstract available.

PMID:
8991506
49.

Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification.

Rietschel ET, Brade H, Holst O, Brade L, Müller-Loennies S, Mamat U, Zähringer U, Beckmann F, Seydel U, Brandenburg K, Ulmer AJ, Mattern T, Heine H, Schletter J, Loppnow H, Schönbeck U, Flad HD, Hauschildt S, Schade UF, Di Padova F, Kusumoto S, Schumann RR.

Curr Top Microbiol Immunol. 1996;216:39-81. Review. No abstract available.

PMID:
8791735
50.

Structural investigation on the carbohydrate backbone of the lipopolysaccharide from Klebsiella pneumoniae rough mutant R20/O1-.

Süsskind M, Müller-Loennies S, Nimmich W, Brade H, Holst O.

Carbohydr Res. 1995 Apr 3;269(1):C1-7. No abstract available.

PMID:
7773983

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