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Items: 1 to 50 of 77

1.

Cancer susceptibility of beta HPV49 E6 and E7 transgenic mice to 4-nitroquinoline 1-oxide treatment correlates with mutational signatures of tobacco exposure.

Viarisio D, Robitaille A, Müller-Decker K, Flechtenmacher C, Gissmann L, Tommasino M.

Virology. 2019 Dec;538:53-60. doi: 10.1016/j.virol.2019.09.010. Epub 2019 Sep 24.

PMID:
31569015
2.

A transplantable tumor model allowing investigation of NY-BR-1-specific T cell responses in HLA-DRB1*0401 transgenic mice.

Das K, Eisel D, Vormehr M, Müller-Decker K, Hommertgen A, Jäger D, Zörnig I, Feuerer M, Kopp-Schneider A, Osen W, Eichmüller SB.

BMC Cancer. 2019 Sep 13;19(1):914. doi: 10.1186/s12885-019-6102-6.

3.

Combined inhibition of Bcl-2 and NFκB synergistically induces cell death in cutaneous T-cell lymphoma.

Froehlich TC, Müller-Decker K, Braun JD, Albrecht T, Schroeder A, Gülow K, Goerdt S, Krammer PH, Nicolay JP.

Blood. 2019 Aug 1;134(5):445-455. doi: 10.1182/blood.2019001545. Epub 2019 Jun 5.

PMID:
31167801
4.

MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer.

Zhan T, Ambrosi G, Wandmacher AM, Rauscher B, Betge J, Rindtorff N, Häussler RS, Hinsenkamp I, Bamberg L, Hessling B, Müller-Decker K, Erdmann G, Burgermeister E, Ebert MP, Boutros M.

Nat Commun. 2019 May 16;10(1):2197. doi: 10.1038/s41467-019-09898-0.

5.

Functional Proteomics of Breast Cancer Metabolism Identifies GLUL as Responder during Hypoxic Adaptation.

Bernhardt S, Tönsing C, Mitra D, Erdem N, Müller-Decker K, Korf U, Kreutz C, Timmer J, Wiemann S.

J Proteome Res. 2019 Mar 1;18(3):1352-1362. doi: 10.1021/acs.jproteome.8b00944. Epub 2019 Jan 18.

PMID:
30609375
6.

Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification.

Melnik S, Dvornikov D, Müller-Decker K, Depner S, Stannek P, Meister M, Warth A, Thomas M, Muley T, Risch A, Plass C, Klingmüller U, Niehrs C, Glinka A.

Cell Discov. 2018 Jul 3;4:37. doi: 10.1038/s41421-018-0033-2. eCollection 2018.

7.

Beta HPV38 oncoproteins act with a hit-and-run mechanism in ultraviolet radiation-induced skin carcinogenesis in mice.

Viarisio D, Müller-Decker K, Accardi R, Robitaille A, Dürst M, Beer K, Jansen L, Flechtenmacher C, Bozza M, Harbottle R, Voegele C, Ardin M, Zavadil J, Caldeira S, Gissmann L, Tommasino M.

PLoS Pathog. 2018 Jan 11;14(1):e1006783. doi: 10.1371/journal.ppat.1006783. eCollection 2018 Jan.

8.

Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence.

Rios Garcia M, Steinbauer B, Srivastava K, Singhal M, Mattijssen F, Maida A, Christian S, Hess-Stumpp H, Augustin HG, Müller-Decker K, Nawroth PP, Herzig S, Berriel Diaz M.

Cell Metab. 2017 Dec 5;26(6):842-855.e5. doi: 10.1016/j.cmet.2017.09.018. Epub 2017 Oct 19.

9.

Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells.

Schweizer PA, Darche FF, Ullrich ND, Geschwill P, Greber B, Rivinius R, Seyler C, Müller-Decker K, Draguhn A, Utikal J, Koenen M, Katus HA, Thomas D.

Stem Cell Res Ther. 2017 Oct 16;8(1):229. doi: 10.1186/s13287-017-0681-4.

10.

A Hepatic GAbp-AMPK Axis Links Inflammatory Signaling to Systemic Vascular Damage.

Niopek K, Üstünel BE, Seitz S, Sakurai M, Zota A, Mattijssen F, Wang X, Sijmonsma T, Feuchter Y, Gail AM, Leuchs B, Niopek D, Staufer O, Brune M, Sticht C, Gretz N, Müller-Decker K, Hammes HP, Nawroth P, Fleming T, Conkright MD, Blüher M, Zeigerer A, Herzig S, Berriel Diaz M.

Cell Rep. 2017 Aug 8;20(6):1422-1434. doi: 10.1016/j.celrep.2017.07.023.

11.

Models in Translational Oncology: A Public Resource Database for Preclinical Cancer Research.

Galuschka C, Proynova R, Roth B, Augustin HG, Müller-Decker K.

Cancer Res. 2017 May 15;77(10):2557-2563. doi: 10.1158/0008-5472.CAN-16-3099. Review.

12.

The BRAF Inhibitor Vemurafenib Enhances UV-Induced Skin Carcinogenesis in Beta HPV38 E6 and E7 Transgenic Mice.

Viarisio D, Müller-Decker K, Hassel JC, Alvarez JC, Flechtenmacher C, Pawlita M, Gissmann L, Tommasino M.

J Invest Dermatol. 2017 Jan;137(1):261-264. doi: 10.1016/j.jid.2016.08.030. Epub 2016 Sep 17. No abstract available.

13.

K-Ras and cyclooxygenase-2 coactivation augments intraductal papillary mucinous neoplasm and Notch1 mimicking human pancreas lesions.

Chiblak S, Steinbauer B, Pohl-Arnold A, Kucher D, Abdollahi A, Schwager C, Höft B, Esposito I, Müller-Decker K.

Sci Rep. 2016 Jul 6;6:29455. doi: 10.1038/srep29455.

14.

Dimethyl fumarate restores apoptosis sensitivity and inhibits tumor growth and metastasis in CTCL by targeting NF-κB.

Nicolay JP, Müller-Decker K, Schroeder A, Brechmann M, Möbs M, Géraud C, Assaf C, Goerdt S, Krammer PH, Gülow K.

Blood. 2016 Aug 11;128(6):805-15. doi: 10.1182/blood-2016-01-694117. Epub 2016 Jun 6.

15.

Incipient Melanoma Brain Metastases Instigate Astrogliosis and Neuroinflammation.

Schwartz H, Blacher E, Amer M, Livneh N, Abramovitz L, Klein A, Ben-Shushan D, Soffer S, Blazquez R, Barrantes-Freer A, Müller M, Müller-Decker K, Stein R, Tsarfaty G, Satchi-Fainaro R, Umansky V, Pukrop T, Erez N.

Cancer Res. 2016 Aug 1;76(15):4359-71. doi: 10.1158/0008-5472.CAN-16-0485. Epub 2016 Jun 3.

16.

Novel ß-HPV49 Transgenic Mouse Model of Upper Digestive Tract Cancer.

Viarisio D, Müller-Decker K, Zanna P, Kloz U, Aengeneyndt B, Accardi R, Flechtenmacher C, Gissmann L, Tommasino M.

Cancer Res. 2016 Jul 15;76(14):4216-25. doi: 10.1158/0008-5472.CAN-16-0370. Epub 2016 May 23.

17.

Downregulation of the TGFβ Pseudoreceptor BAMBI in Non-Small Cell Lung Cancer Enhances TGFβ Signaling and Invasion.

Marwitz S, Depner S, Dvornikov D, Merkle R, Szczygieł M, Müller-Decker K, Lucarelli P, Wäsch M, Mairbäurl H, Rabe KF, Kugler C, Vollmer E, Reck M, Scheufele S, Kröger M, Ammerpohl O, Siebert R, Goldmann T, Klingmüller U.

Cancer Res. 2016 Jul 1;76(13):3785-801. doi: 10.1158/0008-5472.CAN-15-1326. Epub 2016 May 17.

18.

Mouse redox histology using genetically encoded probes.

Fujikawa Y, Roma LP, Sobotta MC, Rose AJ, Diaz MB, Locatelli G, Breckwoldt MO, Misgeld T, Kerschensteiner M, Herzig S, Müller-Decker K, Dick TP.

Sci Signal. 2016 Mar 15;9(419):rs1. doi: 10.1126/scisignal.aad3895.

PMID:
26980443
19.

Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia.

Schäfer M, Oeing CU, Rohm M, Baysal-Temel E, Lehmann LH, Bauer R, Volz HC, Boutros M, Sohn D, Sticht C, Gretz N, Eichelbaum K, Werner T, Hirt MN, Eschenhagen T, Müller-Decker K, Strobel O, Hackert T, Krijgsveld J, Katus HA, Berriel Diaz M, Backs J, Herzig S.

Mol Metab. 2015 Nov 26;5(2):67-78. doi: 10.1016/j.molmet.2015.11.004. eCollection 2016 Feb.

20.

An in vivo RNAi screen identifies SALL1 as a tumor suppressor in human breast cancer with a role in CDH1 regulation.

Wolf J, Müller-Decker K, Flechtenmacher C, Zhang F, Shahmoradgoli M, Mills GB, Hoheisel JD, Boettcher M.

Oncogene. 2014 Aug 14;33(33):4273-8. doi: 10.1038/onc.2013.515. Epub 2013 Dec 2.

21.

A mammosphere formation RNAi screen reveals that ATG4A promotes a breast cancer stem-like phenotype.

Wolf J, Dewi DL, Fredebohm J, Müller-Decker K, Flechtenmacher C, Hoheisel JD, Boettcher M.

Breast Cancer Res. 2013 Nov 14;15(6):R109. doi: 10.1186/bcr3576.

22.

Impact of S100A8/A9 expression on prostate cancer progression in vitro and in vivo.

Grebhardt S, Müller-Decker K, Bestvater F, Hershfinkel M, Mayer D.

J Cell Physiol. 2014 May;229(5):661-71. doi: 10.1002/jcp.24489.

PMID:
24122301
23.

TSC22D4 is a molecular output of hepatic wasting metabolism.

Jones A, Friedrich K, Rohm M, Schäfer M, Algire C, Kulozik P, Seibert O, Müller-Decker K, Sijmonsma T, Strzoda D, Sticht C, Gretz N, Dallinga-Thie GM, Leuchs B, Kögl M, Stremmel W, Diaz MB, Herzig S.

EMBO Mol Med. 2013 Feb;5(2):294-308. doi: 10.1002/emmm.201201869. Epub 2013 Jan 11. Erratum in: EMBO Mol Med. 2013 Jun;5(6):965.

24.

Tumor-microenvironment interactions studied by zonal transcriptional profiling of squamous cell lung carcinoma.

Wu H, Haag D, Muley T, Warth A, Zapatka M, Toedt G, Pscherer A, Hahn M, Rieker RJ, Wachter DL, Meister M, Schnabel P, Müller-Decker K, Rogers MA, Hoffmann H, Lichter P.

Genes Chromosomes Cancer. 2013 Mar;52(3):250-64. doi: 10.1002/gcc.22025. Epub 2012 Oct 17.

PMID:
23074073
25.

Deleted in malignant brain tumors 1 is present in the vascular extracellular matrix and promotes angiogenesis.

Müller H, Hu J, Popp R, Schmidt MHH, Müller-Decker K, Mollenhauer J, Fisslthaler B, Eble JA, Fleming I.

Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):442-8. doi: 10.1161/ATVBAHA.111.239830. Epub 2011 Nov 3.

PMID:
22053071
26.

Cyclooxygenase-dependent signaling is causally linked to non-melanoma skin carcinogenesis: pharmacological, genetic, and clinical evidence.

Müller-Decker K.

Cancer Metastasis Rev. 2011 Dec;30(3-4):343-61. doi: 10.1007/s10555-011-9306-z. Review.

PMID:
22038018
27.

Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues.

Aichler M, Seiler C, Tost M, Siveke J, Mazur PK, Da Silva-Buttkus P, Bartsch DK, Langer P, Chiblak S, Dürr A, Höfler H, Klöppel G, Müller-Decker K, Brielmeier M, Esposito I.

J Pathol. 2012 Apr;226(5):723-34. doi: 10.1002/path.3017. Epub 2012 Jan 17.

PMID:
21984419
28.

Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.

Kulozik P, Jones A, Mattijssen F, Rose AJ, Reimann A, Strzoda D, Kleinsorg S, Raupp C, Kleinschmidt J, Müller-Decker K, Wahli W, Sticht C, Gretz N, von Loeffelholz C, Stockmann M, Pfeiffer A, Stöhr S, Dallinga-Thie GM, Nawroth PP, Diaz MB, Herzig S.

Cell Metab. 2011 Apr 6;13(4):389-400. doi: 10.1016/j.cmet.2011.02.011.

29.

Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes.

Vegiopoulos A, Müller-Decker K, Strzoda D, Schmitt I, Chichelnitskiy E, Ostertag A, Berriel Diaz M, Rozman J, Hrabe de Angelis M, Nüsing RM, Meyer CW, Wahli W, Klingenspor M, Herzig S.

Science. 2010 May 28;328(5982):1158-61. doi: 10.1126/science.1186034. Epub 2010 May 6.

30.

Localization of cyclo-oxygenase-2 in human recurrent colorectal cancer.

Loukanov Ts, Kirilov M, Fürstenberger G, Müller-Decker K.

Clin Invest Med. 2010 Feb 1;33(1):E22-9.

PMID:
20144265
31.

Polymorphisms in fatty-acid-metabolism-related genes are associated with colorectal cancer risk.

Hoeft B, Linseisen J, Beckmann L, Müller-Decker K, Canzian F, Hüsing A, Kaaks R, Vogel U, Jakobsen MU, Overvad K, Hansen RD, Knüppel S, Boeing H, Trichopoulou A, Koumantaki Y, Trichopoulos D, Berrino F, Palli D, Panico S, Tumino R, Bueno-de-Mesquita HB, van Duijnhoven FJ, van Gils CH, Peeters PH, Dumeaux V, Lund E, Huerta Castaño JM, Muñoz X, Rodriguez L, Barricarte A, Manjer J, Jirström K, Van Guelpen B, Hallmans G, Spencer EA, Crowe FL, Khaw KT, Wareham N, Morois S, Boutron-Ruault MC, Clavel-Chapelon F, Chajes V, Jenab M, Boffetta P, Vineis P, Mouw T, Norat T, Riboli E, Nieters A.

Carcinogenesis. 2010 Mar;31(3):466-72. doi: 10.1093/carcin/bgp325. Epub 2009 Dec 30.

PMID:
20042636
32.

The glucocorticoid receptor controls hepatic dyslipidemia through Hes1.

Lemke U, Krones-Herzig A, Berriel Diaz M, Narvekar P, Ziegler A, Vegiopoulos A, Cato AC, Bohl S, Klingmüller U, Screaton RA, Müller-Decker K, Kersten S, Herzig S.

Cell Metab. 2008 Sep;8(3):212-23. doi: 10.1016/j.cmet.2008.08.001.

33.

Nuclear receptor cofactor receptor interacting protein 140 controls hepatic triglyceride metabolism during wasting in mice.

Berriel Diaz M, Krones-Herzig A, Metzger D, Ziegler A, Vegiopoulos A, Klingenspor M, Müller-Decker K, Herzig S.

Hepatology. 2008 Sep;48(3):782-91. doi: 10.1002/hep.22383.

PMID:
18712775
34.

RAGE signaling sustains inflammation and promotes tumor development.

Gebhardt C, Riehl A, Durchdewald M, Németh J, Fürstenberger G, Müller-Decker K, Enk A, Arnold B, Bierhaus A, Nawroth PP, Hess J, Angel P.

J Exp Med. 2008 Feb 18;205(2):275-85. doi: 10.1084/jem.20070679. Epub 2008 Jan 21.

35.

cAMP-dependent signaling regulates the adipogenic effect of n-6 polyunsaturated fatty acids.

Madsen L, Pedersen LM, Liaset B, Ma T, Petersen RK, van den Berg S, Pan J, Müller-Decker K, Dülsner ED, Kleemann R, Kooistra T, Døskeland SO, Kristiansen K.

J Biol Chem. 2008 Mar 14;283(11):7196-205. Epub 2007 Dec 10.

36.

The cyclooxygenase-2-mediated prostaglandin signaling is causally related to epithelial carcinogenesis.

Müller-Decker K, Fürstenberger G.

Mol Carcinog. 2007 Aug;46(8):705-10. Review.

PMID:
17546626
37.

The expression pattern of prostaglandin E synthase and EP receptor isoforms in normal mouse skin and preinvasive skin neoplasms.

Neumann M, Dülsner E, Fürstenberger G, Müller-Decker K.

Exp Dermatol. 2007 May;16(5):445-53.

PMID:
17437488
38.

Tumor promotion as a target of cancer prevention.

Marks F, Fürstenberger G, Müller-Decker K.

Recent Results Cancer Res. 2007;174:37-47. Review.

PMID:
17302183
39.

What are cyclooxygenases and lipoxygenases doing in the driver's seat of carcinogenesis?

Fürstenberger G, Krieg P, Müller-Decker K, Habenicht AJ.

Int J Cancer. 2006 Nov 15;119(10):2247-54. Review.

40.

Preinvasive duct-derived neoplasms in pancreas of keratin 5-promoter cyclooxygenase-2 transgenic mice.

Müller-Decker K, Fürstenberger G, Annan N, Kucher D, Pohl-Arnold A, Steinbauer B, Esposito I, Chiblak S, Friess H, Schirmacher P, Berger I.

Gastroenterology. 2006 Jun;130(7):2165-78.

PMID:
16762637
41.

Differential protein expression in the epidermis of wild-type and COX-2 transgenic mice.

Müller-Decker K, Furstenberger G, Neumann M, Schnolzer M.

Skin Pharmacol Physiol. 2006;19(2):89-94. Epub 2006 May 9. Review.

PMID:
16685147
42.

Enzymes involved in the biosynthesis of leukotriene B4 and prostaglandin E2 are active in sebaceous glands.

Alestas T, Ganceviciene R, Fimmel S, Müller-Decker K, Zouboulis CC.

J Mol Med (Berl). 2006 Jan;84(1):75-87. Epub 2005 Dec 31.

PMID:
16388388
43.

[Cyclooxygenases in the skin].

Müller-Decker K.

J Dtsch Dermatol Ges. 2004 Aug;2(8):668-75. German.

PMID:
16279229
44.

Transitional cell hyperplasia and carcinomas in urinary bladders of transgenic mice with keratin 5 promoter-driven cyclooxygenase-2 overexpression.

Klein RD, Van Pelt CS, Sabichi AL, Dela Cerda J, Fischer SM, Fürstenberger G, Müller-Decker K.

Cancer Res. 2005 Mar 1;65(5):1808-13.

45.

Inhibition of cell proliferation by bacterial lipopolysaccharides in TLR4-positive epithelial cells: independence of nitric oxide and cytokine release.

Müller-Decker K, Manegold G, Butz H, Hinz DE, Hüttner D, Richter KH, Tremmel M, Weissflog R, Marks F.

J Invest Dermatol. 2005 Mar;124(3):553-61.

46.

Cystic duct dilatations and proliferative epithelial lesions in mouse mammary glands upon keratin 5 promoter-driven overexpression of cyclooxygenase-2.

Müller-Decker K, Berger I, Ackermann K, Ehemann V, Zoubova S, Aulmann S, Pyerin W, Fürstenberger G.

Am J Pathol. 2005 Feb;166(2):575-84.

47.
48.

Arachidonic acid-dependent inhibition of adipocyte differentiation requires PKA activity and is associated with sustained expression of cyclooxygenases.

Petersen RK, Jørgensen C, Rustan AC, Frøyland L, Muller-Decker K, Furstenberger G, Berge RK, Kristiansen K, Madsen L.

J Lipid Res. 2003 Dec;44(12):2320-30. Epub 2003 Aug 16.

49.

Mouse skin as a model for cancer chemoprevention by nonsteroidal anti-inflammatory drugs.

Marks F, Fürstenberger G, Neufang G, Müller-Decker K.

Recent Results Cancer Res. 2003;163:46-57; discussion 264-6. Review.

PMID:
12903842
50.

PAF-receptor in inflammatory versus non inflammatory human epidermis, cell cultures and embryonal cells.

Bayerl C, Brandt H, Niemczyk M, Müller-Decker K, Gretz N.

Inflamm Res. 2003 Jun;52(7):283-6.

PMID:
12861392

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