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Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. Parhizkar S et al. Nat Neurosci. (2019)

Molecular anatomy of a trafficking organelle. Takamori S et al. Cell. (2006)

Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity. Fecher C et al. Nat Neurosci. (2019)

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Items: 1 to 50 of 348


Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis.

Cunha MI, Su M, Cantuti-Castelvetri L, Müller SA, Schifferer M, Djannatian M, Alexopoulos I, van der Meer F, Winkler A, van Ham TJ, Schmid B, Lichtenthaler SF, Stadelmann C, Simons M.

J Exp Med. 2020 May 4;217(5). pii: e20191390. doi: 10.1084/jem.20191390.


Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.

Papadopoulou AA, Müller SA, Mentrup T, Shmueli MD, Niemeyer J, Haug-Kröper M, von Blume J, Mayerhofer A, Feederle R, Schröder B, Lichtenthaler SF, Fluhrer R.

EMBO Rep. 2019 Mar;20(3):e46451. doi: 10.15252/embr.201846451. Epub 2019 Feb 7.


Role of lymphadenectomy, adjuvant chemotherapy, and treatment at high-volume centers in patients with resected pancreatic cancer-a distinct view on lymph node yield.

Warschkow R, Tsai C, Köhn N, Erdem S, Schmied B, Nussbaum DP, Gloor B, Müller SA, Blazer D 3rd, Worni M.

Langenbecks Arch Surg. 2020 Feb 10. doi: 10.1007/s00423-020-01859-2. [Epub ahead of print]


4/5 Gastrectomy in Patients Undergoing Pancreaticoduodenectomy Reduces Delayed Gastric Emptying.

Müller PC, Ruzza C, Kuemmerli C, Steinemann DC, Müller SA, Kessler U, Z'graggen K.

J Surg Res. 2020 Jan 24;249:180-185. doi: 10.1016/j.jss.2019.12.028. [Epub ahead of print]


Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1.

Rudan Njavro J, Klotz J, Dislich B, Wanngren J, Shmueli MD, Herber J, Kuhn PH, Kumar R, Koeglsperger T, Conrad M, Wurst W, Feederle R, Vlachos A, Michalakis S, Jedlicka P, Müller SA, Lichtenthaler SF.

FASEB J. 2020 Feb;34(2):2465-2482. doi: 10.1096/fj.201902347R. Epub 2019 Dec 27.


Posterior enucleation of the pancreatic head: an alternative route of access for parenchyma-sparing pancreatic resection.

Pärli MS, Müller PC, Müller SA, Ruzza CM, Z'graggen K.

Langenbecks Arch Surg. 2019 Dec;404(8):1023-1028. doi: 10.1007/s00423-019-01835-5. Epub 2019 Nov 11.


Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.

Fecher C, Trovò L, Müller SA, Snaidero N, Wettmarshausen J, Heink S, Ortiz O, Wagner I, Kühn R, Hartmann J, Karl RM, Konnerth A, Korn T, Wurst W, Merkler D, Lichtenthaler SF, Perocchi F, Misgeld T.

Nat Neurosci. 2019 Oct;22(10):1731-1742. doi: 10.1038/s41593-019-0479-z. Epub 2019 Sep 9.


Fibril-induced glutamine-/asparagine-rich prions recruit stress granule proteins in mammalian cells.

Riemschoss K, Arndt V, Bolognesi B, von Eisenhart-Rothe P, Liu S, Buravlova O, Duernberger Y, Paulsen L, Hornberger A, Hossinger A, Lorenzo-Gotor N, Hogl S, Müller SA, Tartaglia G, Lichtenthaler SF, Vorberg IM.

Life Sci Alliance. 2019 Jul 2;2(4). pii: e201800280. doi: 10.26508/lsa.201800280. Print 2019 Aug.


Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.

Papadopoulou AA, Müller SA, Mentrup T, Shmueli MD, Niemeyer J, Haug-Kröper M, von Blume J, Mayerhofer A, Feederle R, Schröder B, Lichtenthaler SF, Fluhrer R.

EMBO Rep. 2019 May;20(5). pii: e48133. doi: 10.15252/embr.201948133. No abstract available.


Usefulness of Genetic Testing in Sudden Cardiac Arrest Survivors With or Without Previous Clinical Evidence of Heart Disease.

Asatryan B, Schaller A, Seiler J, Servatius H, Noti F, Baldinger SH, Tanner H, Roten L, Dillier R, Lam A, Haeberlin A, Conte G, Saguner AM, Müller SA, Duru F, Auricchio A, Ammann P, Sticherling C, Burri H, Reichlin T, Wilhelm M, Medeiros-Domingo A.

Am J Cardiol. 2019 Jun 15;123(12):2031-2038. doi: 10.1016/j.amjcard.2019.02.061. Epub 2019 Mar 18.


NrCAM is a marker for substrate-selective activation of ADAM10 in Alzheimer's disease.

Brummer T, Müller SA, Pan-Montojo F, Yoshida F, Fellgiebel A, Tomita T, Endres K, Lichtenthaler SF.

EMBO Mol Med. 2019 Apr;11(4). pii: e9695. doi: 10.15252/emmm.201809695.


Signal Peptide Peptidase-Like 2c (SPPL2c) impairs vesicular transport and cleavage of SNARE proteins.

Papadopoulou AA, Müller SA, Mentrup T, Shmueli MD, Niemeyer J, Haug-Kröper M, von Blume J, Mayerhofer A, Feederle R, Schröder B, Lichtenthaler SF, Fluhrer R.

EMBO Rep. 2019 Mar;20(3). pii: e46451. doi: 10.15252/embr.201846451. Epub 2019 Feb 7. Erratum in: EMBO Rep. 2019 May;20(5):.


The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban.

Niemeyer J, Mentrup T, Heidasch R, Müller SA, Biswas U, Meyer R, Papadopoulou AA, Dederer V, Haug-Kröper M, Adamski V, Lüllmann-Rauch R, Bergmann M, Mayerhofer A, Saftig P, Wennemuth G, Jessberger R, Fluhrer R, Lichtenthaler SF, Lemberg MK, Schröder B.

EMBO Rep. 2019 Mar;20(3). pii: e46449. doi: 10.15252/embr.201846449. Epub 2019 Feb 7.


Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.

Parhizkar S, Arzberger T, Brendel M, Kleinberger G, Deussing M, Focke C, Nuscher B, Xiong M, Ghasemigharagoz A, Katzmarski N, Krasemann S, Lichtenthaler SF, Müller SA, Colombo A, Monasor LS, Tahirovic S, Herms J, Willem M, Pettkus N, Butovsky O, Bartenstein P, Edbauer D, Rominger A, Ertürk A, Grathwohl SA, Neher JJ, Holtzman DM, Meyer-Luehmann M, Haass C.

Nat Neurosci. 2019 Feb;22(2):191-204. doi: 10.1038/s41593-018-0296-9. Epub 2019 Jan 7.


Response of the Injured Tendon to Growth Factors in the Presence or Absence of the Paratenon.

Müller SA, Quirk NP, Müller-Lebschi JA, Heisterbach PE, Dürselen L, Majewski M, Evans CH.

Am J Sports Med. 2019 Feb;47(2):462-467. doi: 10.1177/0363546518814534. Epub 2018 Dec 14.


Effects of freeze-thaw on the biomechanical and structural properties of the rat Achilles tendon.

Quirk NP, Lopez De Padilla C, De La Vega RE, Coenen MJ, Tovar A, Evans CH, Müller SA.

J Biomech. 2018 Nov 16;81:52-57. doi: 10.1016/j.jbiomech.2018.09.012. Epub 2018 Sep 15.


Increased TIMP-3 expression alters the cellular secretome through dual inhibition of the metalloprotease ADAM10 and ligand-binding of the LRP-1 receptor.

Scilabra SD, Pigoni M, Pravatá V, Schätzl T, Müller SA, Troeberg L, Lichtenthaler SF.

Sci Rep. 2018 Oct 2;8(1):14697. doi: 10.1038/s41598-018-32910-4.


Routinely measured hematological parameters and prediction of recurrent vascular events in patients with clinically manifest vascular disease.

Kofink D, Muller SA, Patel RS, Dorresteijn JAN, Berkelmans GFN, de Groot MCH, van Solinge WW, Haitjema S, Leiner T, Visseren FLJ, Hoefer IE, Asselbergs FW; SMART Study Group.

PLoS One. 2018 Sep 7;13(9):e0202682. doi: 10.1371/journal.pone.0202682. eCollection 2018.


An Improved, Chemically Modified RNA Encoding BMP-2 Enhances Osteogenesis In Vitro and In Vivo.

Zhang W, De La Vega RE, Coenen MJ, Müller SA, Peniche Silva CJ, Aneja MK, Plank C, van Griensven M, Evans CH, Balmayor ER.

Tissue Eng Part A. 2019 Jan;25(1-2):131-144. doi: 10.1089/ten.TEA.2018.0112. Epub 2018 Oct 3.


Improved tendon healing using bFGF, BMP-12 and TGFβ1 in a rat model.

Majewski M, Heisterbach P, Jaquiéry C, Dürselen L, Todorov A, Martin I, Evans CH, Müller SA.

Eur Cell Mater. 2018 Jun 13;35:318-334. doi: 10.22203/eCM.v035a22.


CADASIL brain vessels show a HTRA1 loss-of-function profile.

Zellner A, Scharrer E, Arzberger T, Oka C, Domenga-Denier V, Joutel A, Lichtenthaler SF, Müller SA, Dichgans M, Haffner C.

Acta Neuropathol. 2018 Jul;136(1):111-125. doi: 10.1007/s00401-018-1853-8. Epub 2018 May 3.


Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome.

Herber J, Njavro J, Feederle R, Schepers U, Müller UC, Bräse S, Müller SA, Lichtenthaler SF.

Mol Cell Proteomics. 2018 Aug;17(8):1487-1501. doi: 10.1074/mcp.RA118.000608. Epub 2018 May 1.


The Role of the Paratenon in Achilles Tendon Healing: A Study in Rats.

Müller SA, Evans CH, Heisterbach PE, Majewski M.

Am J Sports Med. 2018 Apr;46(5):1214-1219. doi: 10.1177/0363546518756093. Epub 2018 Mar 5.


Miniaturizing EM Sample Preparation: Opportunities, Challenges, and "Visual Proteomics".

Arnold SA, Müller SA, Schmidli C, Syntychaki A, Rima L, Chami M, Stahlberg H, Goldie KN, Braun T.

Proteomics. 2018 Mar;18(5-6):e1700176. doi: 10.1002/pmic.201700176. Review.


Proteome Data Improves Protein Function Prediction in the Interactome of Helicobacter pylori.

Wuchty S, Müller SA, Caufield JH, Häuser R, Aloy P, Kalkhof S, Uetz P.

Mol Cell Proteomics. 2018 May;17(5):961-973. doi: 10.1074/mcp.RA117.000474. Epub 2018 Feb 1.


An optimised version of the secretome protein enrichment with click sugars (SPECS) method leads to enhanced coverage of the secretome.

Serdaroglu A, Müller SA, Schepers U, Bräse S, Weichert W, Lichtenthaler SF, Kuhn PH.

Proteomics. 2017 Mar;17(5). doi: 10.1002/pmic.201600423. Epub 2017 Jan 31.


Short- versus long-term complementary nutritional support via needle catheter jejunostomy after pancreaticoduodenectomy: Study protocol of a randomized controlled trial.

Müller PC, Probst P, Moltzahn F, Steinemann DC, Pärli MS, Schmid SW, Müller SA, Z'graggen K.

Int J Surg Protoc. 2016 Nov 21;3:1-6. doi: 10.1016/j.isjp.2016.11.001. eCollection 2017.


Proteomic Substrate Identification for Membrane Proteases in the Brain.

Müller SA, Scilabra SD, Lichtenthaler SF.

Front Mol Neurosci. 2016 Oct 13;9:96. eCollection 2016. Review.


Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.

Pigoni M, Wanngren J, Kuhn PH, Munro KM, Gunnersen JM, Takeshima H, Feederle R, Voytyuk I, De Strooper B, Levasseur MD, Hrupka BJ, Müller SA, Lichtenthaler SF.

Mol Neurodegener. 2016 Oct 5;11(1):67.


Case-matched study of lesser versus greater curvature approach in laparoscopic Warshaw pancreatectomy.

Müller PC, Müller SA, Steinemann DC, Pärli MS, Moltzahn F, Schmid SW, Z'graggen K.

Am J Surg. 2017 Apr;213(4):711-717. doi: 10.1016/j.amjsurg.2016.05.015. Epub 2016 Jul 21.


Dissecting the interaction between tissue inhibitor of metalloproteinases-3 (TIMP-3) and low density lipoprotein receptor-related protein-1 (LRP-1): Development of a "TRAP" to increase levels of TIMP-3 in the tissue.

Scilabra SD, Yamamoto K, Pigoni M, Sakamoto K, Müller SA, Papadopoulou A, Lichtenthaler SF, Troeberg L, Nagase H, Kadomatsu K.

Matrix Biol. 2017 May;59:69-79. doi: 10.1016/j.matbio.2016.07.004. Epub 2016 Jul 29.


Autograft versus sterilized allograft for lateral calcaneal lengthening osteotomies: Comparison of 50 patients.

Müller SA, Barg A, Vavken P, Valderrabano V, Müller AM.

Medicine (Baltimore). 2016 Jul;95(30):e4343. doi: 10.1097/MD.0000000000004343.


Contributions of the lower dimer to supramolecular actin patterning revealed by TIRF microscopy.

Silván U, Hyotyla J, Mannherz HG, Ringler P, Müller SA, Aebi U, Maier T, Schoenenberger CA.

J Struct Biol. 2016 Aug;195(2):159-166. doi: 10.1016/j.jsb.2016.05.008. Epub 2016 May 14.


Effect of a Simple Collagen Type I Sponge for Achilles Tendon Repair in a Rat Model.

Müller SA, Dürselen L, Heisterbach P, Evans C, Majewski M.

Am J Sports Med. 2016 Aug;44(8):1998-2004. doi: 10.1177/0363546516641942. Epub 2016 Apr 22.


Does caffeine reduce postoperative bowel paralysis after elective laparoscopic colectomy? (CaCo trial): study protocol for a randomized controlled trial.

Kruse C, Müller SA, Warschkow R, Lüthi C, Brunner W, Marti L, Sulz MC, Schmied BM, Tarantino I, Beutner U.

Trials. 2016 Apr 4;17:186. doi: 10.1186/s13063-016-1297-1.


Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP.

Lauer ME, Graff-Meyer A, Rufer AC, Maugeais C, von der Mark E, Matile H, D'Arcy B, Magg C, Ringler P, Müller SA, Scherer S, Dernick G, Thoma R, Hennig M, Niesor EJ, Stahlberg H.

J Struct Biol. 2016 May;194(2):191-8. doi: 10.1016/j.jsb.2016.02.016. Epub 2016 Feb 12.


Principles Governing the Self-Assembly of Coiled-Coil Protein Nanoparticles.

Indelicato G, Wahome N, Ringler P, Müller SA, Nieh MP, Burkhard P, Twarock R.

Biophys J. 2016 Feb 2;110(3):646-660. doi: 10.1016/j.bpj.2015.10.057.


Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells.

Schulz AM, Stutte S, Hogl S, Luckashenak N, Dudziak D, Leroy C, Forné I, Imhof A, Müller SA, Brakebusch CH, Lichtenthaler SF, Brocker T.

J Cell Biol. 2015 Nov 9;211(3):553-67. doi: 10.1083/jcb.201503128.


Very high-density lipoprotein and vitellin as carriers of novel biliverdins IXα with a farnesyl side-chain presumably derived from heme A in Spodoptera littoralis.

Kayser H, Nimtz M, Ringler P, Müller SA.

Insect Biochem Mol Biol. 2016 Jan;68:41-51. doi: 10.1016/j.ibmb.2015.10.017. Epub 2015 Nov 4.


Patients with Adenocarcinoma of the Small Intestine with 9 or More Regional Lymph Nodes Retrieved Have a Higher Rate of Positive Lymph Nodes and Improved Survival.

Wilhelm A, Müller SA, Steffen T, Schmied BM, Beutner U, Warschkow R.

J Gastrointest Surg. 2016 Feb;20(2):401-10.


Label-free Quantitative Proteomics of Mouse Cerebrospinal Fluid Detects β-Site APP Cleaving Enzyme (BACE1) Protease Substrates In Vivo.

Dislich B, Wohlrab F, Bachhuber T, Müller SA, Kuhn PH, Hogl S, Meyer-Luehmann M, Lichtenthaler SF.

Mol Cell Proteomics. 2015 Oct;14(10):2550-63. doi: 10.1074/mcp.M114.041533. Epub 2015 Jul 2.


Optimizing the design of protein nanoparticles as carriers for vaccine applications.

Doll TA, Neef T, Duong N, Lanar DE, Ringler P, Müller SA, Burkhard P.

Nanomedicine. 2015 Oct;11(7):1705-13. doi: 10.1016/j.nano.2015.05.003. Epub 2015 Jun 4.


Stable isotope labeling by amino acids in cell culture based proteomics reveals differences in protein abundances between spiral and coccoid forms of the gastric pathogen Helicobacter pylori.

Müller SA, Pernitzsch SR, Haange SB, Uetz P, von Bergen M, Sharma CM, Kalkhof S.

J Proteomics. 2015 Aug 3;126:34-45. doi: 10.1016/j.jprot.2015.05.011. Epub 2015 May 12.


High prevalence of anaemia among African migrants in Germany persists after exclusion of iron deficiency and erythrocyte polymorphisms.

Müller SA, Amoah SK, Meese S, Spranger J, Mockenhaupt FP.

Trop Med Int Health. 2015 Sep;20(9):1180-1189. doi: 10.1111/tmi.12530. Epub 2015 May 21.


Simulated activity but real trauma: a systematic review on Nintendo Wii injuries based on a case report of an acute anterior cruciate ligament rupture.

Müller SA, Vavken P, Pagenstert G.

Medicine (Baltimore). 2015 Mar;94(12):e648. doi: 10.1097/MD.0000000000000648. Review.


Survival after renal cell carcinoma metastasis to the thyroid: single center experience and systematic review of the literature.

Beutner U, Leowardi C, Bork U, Lüthi C, Tarantino I, Pahernik S, Wente MN, Büchler MW, Schmied BM, Müller SA.

Thyroid. 2015 Mar;25(3):314-24. doi: 10.1089/thy.2014.0498. Epub 2015 Jan 14. Review.


Biologics for tendon repair.

Docheva D, Müller SA, Majewski M, Evans CH.

Adv Drug Deliv Rev. 2015 Apr;84:222-39. doi: 10.1016/j.addr.2014.11.015. Epub 2014 Nov 21. Review.


Integration of conventional quantitative and phospho-proteomics reveals new elements in activated Jurkat T-cell receptor pathway maintenance.

Jouy F, Müller SA, Wagner J, Otto W, von Bergen M, Tomm JM.

Proteomics. 2015 Jan;15(1):25-33. doi: 10.1002/pmic.201400119. Epub 2014 Dec 10.


Baseline mortality-adjusted survival in resected rectal cancer patients.

Tarantino I, Müller SA, Warschkow R, Kulu Y, Schmied BM, Büchler MW, Ulrich A.

J Gastrointest Surg. 2014 Oct;18(10):1837-44. doi: 10.1007/s11605-014-2618-x. Epub 2014 Aug 5.


Use of human fibrin glue (Tisseel) versus staples for mesh fixation in laparoscopic transabdominal preperitoneal hernioplasty (TISTA): a randomized controlled trial (NCT01641718).

Müller SA, Warschkow R, Beutner U, Lüthi C, Ukegjini K, Schmied BM, Tarantino I.

BMC Surg. 2014 Apr 1;14:18. doi: 10.1186/1471-2482-14-18.

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