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Items: 1 to 50 of 116

1.

A randomized, placebo-controlled trial of canakinumab in patients with peripheral artery disease.

Russell KS, Yates DP, Kramer CM, Feller A, Mahling P, Colin L, Clough T, Wang T, LaPerna L, Patel A, Lawall H, Shennak MM, Fulmer J, Nikol S, Smith WB, Müller OJ, Ratchford EV, Basson CT.

Vasc Med. 2019 Jul 5:1358863X19859072. doi: 10.1177/1358863X19859072. [Epub ahead of print]

PMID:
31277561
2.

O-GlcNAcylation of Histone Deacetylase 4 Protects the Diabetic Heart from Failure.

Kronlage M, Dewenter M, Grosso J, Fleming T, Oehl UY, Lehmann LH, Falcão-Pires I, Leite-Moreira AF, Volk N, Gröne HJ, Müller OJ, Sickmann A, Katus HA, Backs J.

Circulation. 2019 Jun 14. doi: 10.1161/CIRCULATIONAHA.117.031942. [Epub ahead of print]

PMID:
31195810
3.

CaMKII activation participates in doxorubicin cardiotoxicity and is attenuated by moderate GRP78 overexpression.

Tscheschner H, Meinhardt E, Schlegel P, Jungmann A, Lehmann LH, Müller OJ, Most P, Katus HA, Raake PW.

PLoS One. 2019 Apr 29;14(4):e0215992. doi: 10.1371/journal.pone.0215992. eCollection 2019.

4.

Anticoagulation in addition to dual antiplatelet therapy has no impact on long-term follow-up after endovascular treatment of (sub)acute lower limb ischemia.

Kronlage M, Blessing E, Müller OJ, Heilmeier B, Katus HA, Erbel C.

Vasa. 2019 Jul;48(4):321-329. doi: 10.1024/0301-1526/a000786. Epub 2019 Apr 8.

PMID:
30958111
5.

Marfan syndrome: A therapeutic challenge for long-term care.

Wagner AH, Zaradzki M, Arif R, Remes A, Müller OJ, Kallenbach K.

Biochem Pharmacol. 2019 Jun;164:53-63. doi: 10.1016/j.bcp.2019.03.034. Epub 2019 Mar 27. Review.

PMID:
30926475
6.

Various effects of AAV9-mediated βARKct gene therapy on the heart in dystrophin-deficient (mdx) mice and δ-sarcoglycan-deficient (Sgcd-/-) mice.

Bauer R, Enns H, Jungmann A, Leuchs B, Volz C, Schinkel S, Koch WJ, Raake PW, Most P, Katus HA, Müller OJ.

Neuromuscul Disord. 2019 Mar;29(3):231-241. doi: 10.1016/j.nmd.2018.12.006. Epub 2018 Dec 20.

PMID:
30782477
7.

Cardio-toxicity of checkpoint inhibitors.

Müller OJ, Spehlmann ME, Frey N.

J Thorac Dis. 2018 Dec;10(Suppl 35):S4400-S4404. doi: 10.21037/jtd.2018.12.78. Review.

8.

Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response.

Binder P, Wang S, Radu M, Zin M, Collins L, Khan S, Li Y, Sekeres K, Humphreys N, Swanton E, Reid A, Pu F, Oceandy D, Guan K, Hille SS, Frey N, Müller OJ, Cartwright EJ, Chernoff J, Wang X, Liu W.

Circ Res. 2019 Mar;124(5):696-711. doi: 10.1161/CIRCRESAHA.118.312829.

9.

ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb.

Blackwood EA, Hofmann C, Santo Domingo M, Bilal AS, Sarakki A, Stauffer W, Arrieta A, Thuerauf DJ, Kolkhorst FW, Müller OJ, Jakobi T, Dieterich C, Katus HA, Doroudgar S, Glembotski CC.

Circ Res. 2019 Jan 4;124(1):79-93. doi: 10.1161/CIRCRESAHA.118.313854.

PMID:
30582446
10.

Comprehensive plasma and tissue profiling reveals systemic metabolic alterations in cardiac hypertrophy and failure.

Müller OJ, Heckmann MB, Ding L, Rapti K, Rangrez AY, Gerken T, Christiansen N, Rennefahrt UEE, Witt H, González Maldonado S, Ternes P, Schwab DM, Ruf T, Hille S, Remes A, Jungmann A, Weis TM, Kreußer JS, Gröne HJ, Backs J, Schatz P, Katus HA, Frey N.

Cardiovasc Res. 2019 Jul 1;115(8):1296-1305. doi: 10.1093/cvr/cvy274.

PMID:
30418544
11.

Impact of thrombin injection in femoral artery pseudoaneurysms with AV-fistula.

Müller OJ, Frey N.

Vasa. 2018 Oct;47(6):437-438. doi: 10.1024/0301-1526/a000734. No abstract available.

12.

Optical prediction of single muscle fiber force production using a combined biomechatronics and second harmonic generation imaging approach.

Schneidereit D, Nübler S, Prölß G, Reischl B, Schürmann S, Müller OJ, Friedrich O.

Light Sci Appl. 2018 Oct 24;7:79. doi: 10.1038/s41377-018-0080-3. eCollection 2018.

13.

Reduction of Transplant Vasculopathy by Intraoperative Nucleic Acid-based Therapy in a Mouse Aortic Allograft Model.

Arif R, Franz M, Remes A, Zaradzki M, Hecker M, Karck M, Müller OJ, Kallenbach K, Wagner AH.

Thorac Cardiovasc Surg. 2018 Oct 23. doi: 10.1055/s-0038-1673633. [Epub ahead of print]

PMID:
30352477
14.

Author response.

Stoll F, Gödde M, Leo A, Katus HA, Müller OJ.

Clin Cardiol. 2018 Dec;41(12):1528. doi: 10.1002/clc.23084. Epub 2018 Oct 4. No abstract available.

15.

Characterization of hospitalized cardiovascular patients with suspected heparin-induced thrombocytopenia.

Stoll F, Gödde M, Leo A, Katus HA, Müller OJ.

Clin Cardiol. 2018 Dec;41(12):1521-1526. doi: 10.1002/clc.23061. Epub 2018 Dec 3.

16.

Stage-dependent remodeling of projections to motor cortex in ALS mouse model revealed by a new variant retrograde-AAV9.

Commisso B, Ding L, Varadi K, Gorges M, Bayer D, Boeckers TM, Ludolph AC, Kassubek J, Müller OJ, Roselli F.

Elife. 2018 Aug 23;7. pii: e36892. doi: 10.7554/eLife.36892.

17.

Dried-Blood-Spot Technique to Monitor Direct Oral Anticoagulants: Clinical Validation of a UPLC-MS/MS-Based Assay.

Foerster KI, Huppertz A, Meid AD, Müller OJ, Rizos T, Tilemann L, Haefeli WE, Burhenne J.

Anal Chem. 2018 Aug 7;90(15):9395-9402. doi: 10.1021/acs.analchem.8b02046. Epub 2018 Jul 17.

PMID:
29985592
18.

A gene therapeutic approach to inhibit calcium and integrin binding protein 1 ameliorates maladaptive remodelling in pressure overload.

Grund A, Szaroszyk M, Döppner JK, Malek Mohammadi M, Kattih B, Korf-Klingebiel M, Gigina A, Scherr M, Kensah G, Jara-Avaca M, Gruh I, Martin U, Wollert KC, Gohla A, Katus HA, Müller OJ, Bauersachs J, Heineke J.

Cardiovasc Res. 2019 Jan 1;115(1):71-82. doi: 10.1093/cvr/cvy154.

PMID:
29931050
19.

Long-term heart-specific mortality among 347 476 breast cancer patients treated with radiotherapy or chemotherapy: a registry-based cohort study.

Weberpals J, Jansen L, Müller OJ, Brenner H.

Eur Heart J. 2018 Nov 14;39(43):3896-3903. doi: 10.1093/eurheartj/ehy167.

PMID:
29635274
20.

Ion Channel Dysfunctions in Dilated Cardiomyopathy in Limb-Girdle Muscular Dystrophy.

El-Battrawy I, Zhao Z, Lan H, Li X, Yücel G, Lang S, Sattler K, Schünemann JD, Zimmermann WH, Cyganek L, Utikal J, Wieland T, Bieback K, Bauer R, Ratte A, Pribe-Wolferts R, Rapti K, Nowak D, Wittig J, Thomas D, Most P, Katus HA, Ravens U, Schmidt C, Borggrefe M, Zhou XB, Müller OJ, Akin I.

Circ Genom Precis Med. 2018 Mar;11(3):e001893. doi: 10.1161/CIRCGEN.117.001893.

PMID:
29545480
21.

Cardio-oncology: conflicting priorities of anticancer treatment and cardiovascular outcome.

Tilemann LM, Heckmann MB, Katus HA, Lehmann LH, Müller OJ.

Clin Res Cardiol. 2018 Apr;107(4):271-280. doi: 10.1007/s00392-018-1202-x. Epub 2018 Feb 16. Review.

22.

AAV-9 mediated phosphatase-1 inhibitor-1 overexpression improves cardiac contractility in unchallenged mice but is deleterious in pressure-overload.

Schwab DM, Tilemann L, Bauer R, Heckmann M, Jungmann A, Wagner M, Burgis J, Vettel C, Katus HA, El-Armouche A, Müller OJ.

Gene Ther. 2018 Jan;25(1):13-19. doi: 10.1038/gt.2017.97. Epub 2018 Jan 19.

PMID:
29350681
23.

AP-1 Oligodeoxynucleotides Reduce Aortic Elastolysis in a Murine Model of Marfan Syndrome.

Arif R, Zaradzki M, Remes A, Seppelt P, Kunze R, Schröder H, Schwill S, Ensminger SM, Robinson PN, Karck M, Müller OJ, Hecker M, Wagner AH, Kallenbach K.

Mol Ther Nucleic Acids. 2017 Dec 15;9:69-79. doi: 10.1016/j.omtn.2017.08.014. Epub 2017 Sep 20.

24.

A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.

Lehmann LH, Jebessa ZH, Kreusser MM, Horsch A, He T, Kronlage M, Dewenter M, Sramek V, Oehl U, Krebs-Haupenthal J, von der Lieth AH, Schmidt A, Sun Q, Ritterhoff J, Finke D, Völkers M, Jungmann A, Sauer SW, Thiel C, Nickel A, Kohlhaas M, Schäfer M, Sticht C, Maack C, Gretz N, Wagner M, El-Armouche A, Maier LS, Londoño JEC, Meder B, Freichel M, Gröne HJ, Most P, Müller OJ, Herzig S, Furlong EEM, Katus HA, Backs J.

Nat Med. 2018 Jan;24(1):62-72. doi: 10.1038/nm.4452. Epub 2017 Dec 11.

PMID:
29227474
25.

Platelet function monitoring for stent thrombosis in critically III patients with an acute Coronary syndrome.

Tilemann L, Mohr SK, Preusch M, Chorianopoulos E, Giannitsis E, Katus HA, Müller OJ.

J Interv Cardiol. 2018 Jun;31(3):277-283. doi: 10.1111/joic.12474. Epub 2017 Dec 6.

PMID:
29214676
26.

Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy.

Hu J, Dziumbla S, Lin J, Bibli SI, Zukunft S, de Mos J, Awwad K, Frömel T, Jungmann A, Devraj K, Cheng Z, Wang L, Fauser S, Eberhart CG, Sodhi A, Hammock BD, Liebner S, Müller OJ, Glaubitz C, Hammes HP, Popp R, Fleming I.

Nature. 2017 Dec 14;552(7684):248-252. doi: 10.1038/nature25013. Epub 2017 Dec 6.

27.

Idiopathic catastrophic thrombosis with happy ending.

Heid J, Greinacher A, Katus HA, Müller OJ.

BMJ Case Rep. 2017 Oct 23;2017. pii: bcr-2017-221194. doi: 10.1136/bcr-2017-221194.

PMID:
29066639
28.

Short vs prolonged dual antiplatelet treatment upon endovascular stenting of peripheral arteries.

Kronlage M, Wassmann M, Vogel B, Müller OJ, Blessing E, Katus H, Erbel C.

Drug Des Devel Ther. 2017 Oct 6;11:2937-2945. doi: 10.2147/DDDT.S143226. eCollection 2017.

29.

Simultaneous quantification of direct oral anticoagulants currently used in anticoagulation therapy.

Foerster KI, Huppertz A, Müller OJ, Rizos T, Tilemann L, Haefeli WE, Burhenne J.

J Pharm Biomed Anal. 2018 Jan 30;148:238-244. doi: 10.1016/j.jpba.2017.10.011. Epub 2017 Oct 16.

PMID:
29055248
30.

Protocol for Efficient Generation and Characterization of Adeno-Associated Viral Vectors.

Jungmann A, Leuchs B, Rommelaere J, Katus HA, Müller OJ.

Hum Gene Ther Methods. 2017 Oct;28(5):235-246. doi: 10.1089/hgtb.2017.192.

PMID:
29048971
31.

Protocol for efficient generation and characterization of adeno-associated viral (AAV) vectors.

Jungmann A, Leuchs B, Katus HA, Rommelaere J, Müller OJ.

Hum Gene Ther Methods. 2017 Sep 21. doi: 10.1089/hum.2017.192. [Epub ahead of print]

PMID:
28934862
32.

Metabolic stress-induced cardiomyopathy is caused by mitochondrial dysfunction due to attenuated Erk5 signaling.

Liu W, Ruiz-Velasco A, Wang S, Khan S, Zi M, Jungmann A, Dolores Camacho-Muñoz M, Guo J, Du G, Xie L, Oceandy D, Nicolaou A, Galli G, Müller OJ, Cartwright EJ, Ji Y, Wang X.

Nat Commun. 2017 Sep 8;8(1):494. doi: 10.1038/s41467-017-00664-8.

33.

The cardiac microenvironment uses non-canonical WNT signaling to activate monocytes after myocardial infarction.

Meyer IS, Jungmann A, Dieterich C, Zhang M, Lasitschka F, Werkmeister S, Haas J, Müller OJ, Boutros M, Nahrendorf M, Katus HA, Hardt SE, Leuschner F.

EMBO Mol Med. 2017 Sep;9(9):1279-1293. doi: 10.15252/emmm.201707565.

34.

Short and long-term results after endovascular management of vascular complications during transfemoral aortic valve implantation.

Heger T, Strauß S, Blessing E, Andrassy M, Erbel C, Müller OJ, Chorianopoulos E, Pleger S, Leuschner F, Korosoglou G, Bekeredjian R, Katus HA, Vogel B.

Acta Cardiol. 2017 Aug;72(4):474-482. doi: 10.1080/00015385.2017.1335455. Epub 2017 Jul 14.

PMID:
28705072
35.

Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease.

Siede D, Rapti K, Gorska AA, Katus HA, Altmüller J, Boeckel JN, Meder B, Maack C, Völkers M, Müller OJ, Backs J, Dieterich C.

J Mol Cell Cardiol. 2017 Aug;109:48-56. doi: 10.1016/j.yjmcc.2017.06.015. Epub 2017 Jul 1.

PMID:
28676412
36.

Evaluation of MYBPC3 trans-Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes.

Prondzynski M, Krämer E, Laufer SD, Shibamiya A, Pless O, Flenner F, Müller OJ, Münch J, Redwood C, Hansen A, Patten M, Eschenhagen T, Mearini G, Carrier L.

Mol Ther Nucleic Acids. 2017 Jun 16;7:475-486. doi: 10.1016/j.omtn.2017.05.008. Epub 2017 May 17.

37.

Complex interventional iliocaval recanalization due to plasmacytoma and cystic echinococcosis.

Stoll F, Kucher N, Vogel B, Katus HA, Müller OJ, Erbel C.

Vasa. 2017 Aug;46(5):395-399. doi: 10.1024/0301-1526/a000636. Epub 2017 Jun 14.

38.

[Choosing wisely recommendations in angiology].

Müller OJ, Sternitzky R.

Internist (Berl). 2017 Jun;58(6):532-538. doi: 10.1007/s00108-017-0252-x. German.

PMID:
28516250
39.

A comparative study on endovascular treatment of (sub)acute critical limb ischemia: mechanical thrombectomy vs thrombolysis.

Kronlage M, Printz I, Vogel B, Blessing E, Müller OJ, Katus HA, Erbel C.

Drug Des Devel Ther. 2017 Apr 18;11:1233-1241. doi: 10.2147/DDDT.S131503. eCollection 2017.

40.

Metabolic profiles in heart failure due to non-ischemic cardiomyopathy at rest and under exercise.

Mueller-Hennessen M, Sigl J, Fuhrmann JC, Witt H, Reszka R, Schmitz O, Kastler J, Fischer JJ, Müller OJ, Giannitsis E, Weis T, Frey N, Katus HA.

ESC Heart Fail. 2017 May;4(2):178-189. doi: 10.1002/ehf2.12133. Epub 2017 Mar 8.

41.

A Novel Lipid Biomarker Panel for the Detection of Heart Failure with Reduced Ejection Fraction.

Mueller-Hennessen M, Düngen HD, Lutz M, Trippel TD, Kreuter M, Sigl J, Müller OJ, Tahirovic E, Witt H, Ternes P, Carvalho S, Peter E, Rein D, Schatz P, Herth F, Giannitsis E, Weis T, Frey N, Katus HA.

Clin Chem. 2017 Jan;63(1):267-277. doi: 10.1373/clinchem.2016.257279. Epub 2016 Oct 25.

42.

C1q-TNF-Related Protein-9 Promotes Cardiac Hypertrophy and Failure.

Appari M, Breitbart A, Brandes F, Szaroszyk M, Froese N, Korf-Klingebiel M, Mohammadi MM, Grund A, Scharf GM, Wang H, Zwadlo C, Fraccarollo D, Schrameck U, Nemer M, Wong GW, Katus HA, Wollert KC, Müller OJ, Bauersachs J, Heineke J.

Circ Res. 2017 Jan 6;120(1):66-77. doi: 10.1161/CIRCRESAHA.116.309398. Epub 2016 Nov 7.

PMID:
27821723
43.

Sumoylation-independent activation of Calcineurin-NFAT-signaling via SUMO2 mediates cardiomyocyte hypertrophy.

Bernt A, Rangrez AY, Eden M, Jungmann A, Katz S, Rohr C, Müller OJ, Katus HA, Sossalla ST, Williams T, Ritter O, Frank D, Frey N.

Sci Rep. 2016 Oct 21;6:35758. doi: 10.1038/srep35758.

44.

Inducible cardiomyocyte-specific deletion of CaM kinase II protects from pressure overload-induced heart failure.

Kreusser MM, Lehmann LH, Wolf N, Keranov S, Jungmann A, Gröne HJ, Müller OJ, Katus HA, Backs J.

Basic Res Cardiol. 2016 Nov;111(6):65. Epub 2016 Sep 28.

PMID:
27683174
45.

Adverse Events Following International Normalized Ratio Reversal in Intracerebral Hemorrhage.

Laible M, Jenetzky E, Beynon C, Müller OJ, Sander P, Schüler S, Purrucker J, Möhlenbruch M, Steiner T, Veltkamp R, Ringleb PA, Rizos T.

Cerebrovasc Dis. 2016;42(5-6):446-454. Epub 2016 Aug 19.

46.

Off-resonance magnetic resonance angiography improves visualization of in-stent lumen in peripheral nitinol stents compared to conventional T1-weighted acquisitions: an in vitro comparison study.

Gitsioudis G, Fortner P, Stuber M, Missiou A, Andre F, Müller OJ, Katus HA, Korosoglou G.

Int J Cardiovasc Imaging. 2016 Nov;32(11):1645-1655. Epub 2016 Aug 17.

PMID:
27535040
47.

AMP-activated protein kinase α1-sensitive activation of AP-1 in cardiomyocytes.

Voelkl J, Alesutan I, Primessnig U, Feger M, Mia S, Jungmann A, Castor T, Viereck R, Stöckigt F, Borst O, Gawaz M, Schrickel JW, Metzler B, Katus HA, Müller OJ, Pieske B, Heinzel FR, Lang F.

J Mol Cell Cardiol. 2016 Aug;97:36-43. doi: 10.1016/j.yjmcc.2016.04.009. Epub 2016 Apr 19.

PMID:
27106803
48.

AAV9-mediated gene transfer of desmin ameliorates cardiomyopathy in desmin-deficient mice.

Heckmann MB, Bauer R, Jungmann A, Winter L, Rapti K, Strucksberg KH, Clemen CS, Li Z, Schröder R, Katus HA, Müller OJ.

Gene Ther. 2016 Aug;23(8-9):673-9. doi: 10.1038/gt.2016.40. Epub 2016 Apr 21.

49.

Treatment With Prothrombin Complex Concentrate to Enable Emergency Lumbar Puncture in Patients Receiving Vitamin K Antagonists.

Laible M, Beynon C, Sander P, Purrucker J, Müller OJ, Möhlenbruch M, Ringleb PA, Rizos T.

Ann Emerg Med. 2016 Sep;68(3):340-4. doi: 10.1016/j.annemergmed.2016.03.003. Epub 2016 Apr 14.

PMID:
27085368
50.

Pulmonary Targeting of Adeno-associated Viral Vectors by Next-generation Sequencing-guided Screening of Random Capsid Displayed Peptide Libraries.

Körbelin J, Sieber T, Michelfelder S, Lunding L, Spies E, Hunger A, Alawi M, Rapti K, Indenbirken D, Müller OJ, Pasqualini R, Arap W, Kleinschmidt JA, Trepel M.

Mol Ther. 2016 Jun;24(6):1050-1061. doi: 10.1038/mt.2016.62. Epub 2016 Mar 28.

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