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Items: 1 to 50 of 461

1.

Imaging in Biologically-Relevant Environments with AFM Using Stiff qPlus Sensors.

Pürckhauer K, Weymouth AJ, Pfeffer K, Kullmann L, Mulvihill E, Krahn MP, Müller DJ, Giessibl FJ.

Sci Rep. 2018 Jun 19;8(1):9330. doi: 10.1038/s41598-018-27608-6.

2.

Mechanism of membrane pore formation by human gasdermin-D.

Mulvihill E, Sborgi L, Mari SA, Pfreundschuh M, Hiller S, Müller DJ.

EMBO J. 2018 Jun 13. pii: e98321. doi: 10.15252/embj.201798321. [Epub ahead of print]

3.

Single-Molecule Force Spectroscopy of Transmembrane β-Barrel Proteins.

Thoma J, Sapra KT, Müller DJ.

Annu Rev Anal Chem (Palo Alto Calif). 2018 Jun 12;11(1):375-395. doi: 10.1146/annurev-anchem-061417-010055.

PMID:
29894225
4.

POTRA Domains, Extracellular Lid, and Membrane Composition Modulate the Conformational Stability of the β Barrel Assembly Factor BamA.

Thoma J, Sun Y, Ritzmann N, Müller DJ.

Structure. 2018 May 15. pii: S0969-2126(18)30163-1. doi: 10.1016/j.str.2018.04.017. [Epub ahead of print]

PMID:
29861346
5.

Cells Stiffen for Cytokines.

Newton R, Müller DJ.

Cell Chem Biol. 2018 May 17;25(5):495-496. doi: 10.1016/j.chembiol.2018.05.006.

PMID:
29775601
6.

Structural Properties of the Human Protease-Activated Receptor 1 Changing by a Strong Antagonist.

Spoerri PM, Kato HE, Pfreundschuh M, Mari SA, Serdiuk T, Thoma J, Sapra KT, Zhang C, Kobilka BK, Müller DJ.

Structure. 2018 Jun 5;26(6):829-838.e4. doi: 10.1016/j.str.2018.03.020. Epub 2018 May 3.

PMID:
29731231
7.

Genetic testing for CYP2D6 and CYP2C19 suggests improved outcome for antidepressant and antipsychotic medication.

Walden LM, Brandl EJ, Tiwari AK, Cheema S, Freeman N, Braganza N, Kennedy JL, Müller DJ.

Psychiatry Res. 2018 Mar 9. pii: S0165-1781(17)31330-6. doi: 10.1016/j.psychres.2018.02.055. [Epub ahead of print]

PMID:
29699889
8.

Reversible Cation-Selective Attachment and Self-Assembly of Human Tau on Supported Brain Lipid Membranes.

Mari SA, Wegmann S, Tepper K, Hyman BT, Mandelkow EM, Mandelkow E, Müller DJ.

Nano Lett. 2018 May 9;18(5):3271-3281. doi: 10.1021/acs.nanolett.8b01085. Epub 2018 Apr 17.

PMID:
29644863
9.

GWAS-based machine learning approach to predict duloxetine response in major depressive disorder.

Maciukiewicz M, Marshe VS, Hauschild AC, Foster JA, Rotzinger S, Kennedy JL, Kennedy SH, Müller DJ, Geraci J.

J Psychiatr Res. 2018 Apr;99:62-68. doi: 10.1016/j.jpsychires.2017.12.009. Epub 2018 Feb 2.

PMID:
29407288
10.

The Complex Relationship between Antipsychotic-Induced Weight Gain and Therapeutic Benefits: A Systematic Review and Implications for Treatment.

Raben AT, Marshe VS, Chintoh A, Gorbovskaya I, Müller DJ, Hahn MK.

Front Neurosci. 2018 Jan 22;11:741. doi: 10.3389/fnins.2017.00741. eCollection 2017. Review.

11.

Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update.

Phillips EJ, Sukasem C, Whirl-Carrillo M, Müller DJ, Dunnenberger HM, Chantratita W, Goldspiel B, Chen YT, Carleton BC, George AL Jr, Mushiroda T, Klein T, Gammal RS, Pirmohamed M.

Clin Pharmacol Ther. 2018 Apr;103(4):574-581. doi: 10.1002/cpt.1004. Epub 2018 Feb 2.

PMID:
29392710
12.

[Pharmacogenetics in psychiatry: state of the art].

Müller DJ, Brandl EJ, Degenhardt F, Domschke K, Grabe H, Gruber O, Hebebrand J, Maier W, Menke A, Riemenschneider M, Rietschel M, Rujescu D, Schulze TG, Tebartz van Elst L, Tüscher O, Deckert J; das DGPPN Referat Neurobiologie und Genetik.

Nervenarzt. 2018 Mar;89(3):290-299. doi: 10.1007/s00115-017-0479-8. Review. German.

PMID:
29383410
13.

Genetic testing as a supporting tool in prescribing psychiatric medication: Design and protocol of the IMPACT study.

Herbert D, Neves-Pereira M, Baidya R, Cheema S, Groleau S, Shahmirian A, Tiwari AK, Zai CC, King N, Müller DJ, Kennedy JL.

J Psychiatr Res. 2017 Sep 27. pii: S0022-3956(17)30288-1. doi: 10.1016/j.jpsychires.2017.09.002. [Epub ahead of print]

PMID:
29301639
14.

Verbal memory improvement in first-episode psychosis APOE-ε4 carriers: a pleiotropic effect?

Vila-Rodriguez F, Lang DJ, Baitz H, Gicas K, Thorton AE, Ehmann TS, Smith GN, Barr AM, Torres IJ, Kopala LC, MacEwan GW, Müller DJ, Kennedy JL, Honer WG.

Neuropsychiatr Dis Treat. 2017 Dec 8;13:2945–2953. doi: 10.2147/NDT.S150488. eCollection 2017.

15.

Corrigendum: Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second.

Strohmeyer N, Bharadwaj M, Costell M, Fässler R, Müller DJ.

Nat Mater. 2017 Dec 19;17(1):103. doi: 10.1038/nmat5054.

PMID:
29255228
16.

Virus stamping for targeted single-cell infection in vitro and in vivo.

Schubert R, Trenholm S, Balint K, Kosche G, Cowan CS, Mohr MA, Munz M, Martinez-Martin D, Fläschner G, Newton R, Krol J, Scherf BG, Yonehara K, Wertz A, Ponti A, Ghanem A, Hillier D, Conzelmann KK, Müller DJ, Roska B.

Nat Biotechnol. 2018 Jan;36(1):81-88. doi: 10.1038/nbt.4034. Epub 2017 Dec 18.

PMID:
29251729
17.

The comparative effectiveness of electroencephalographic indices in predicting response to escitalopram therapy in depression: A pilot study.

Baskaran A, Farzan F, Milev R, Brenner CA, Alturi S, Pat McAndrews M, Blier P, Evans K, Foster JA, Frey BN, Giacobbe P, Lam RW, Leri F, MacQueen GM, Müller DJ, Parikh SV, Rotzinger S, Soares CN, Strother SC, Turecki G, Kennedy SH; CAN-BIND Investigators Team.

J Affect Disord. 2018 Feb;227:542-549. doi: 10.1016/j.jad.2017.10.028. Epub 2017 Nov 3.

PMID:
29169123
18.

Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second.

Strohmeyer N, Bharadwaj M, Costell M, Fässler R, Müller DJ.

Nat Mater. 2017 Dec;16(12):1262-1270. doi: 10.1038/nmat5023. Epub 2017 Nov 6. Erratum in: Nat Mater. 2017 Dec 19;17 (1):103.

PMID:
29115292
19.

Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding.

Toyoda Y, Cattin CJ, Stewart MP, Poser I, Theis M, Kurzchalia TV, Buchholz F, Hyman AA, Müller DJ.

Nat Commun. 2017 Nov 2;8(1):1266. doi: 10.1038/s41467-017-01147-6.

20.

Inertial picobalance reveals fast mass fluctuations in mammalian cells.

Martínez-Martín D, Fläschner G, Gaub B, Martin S, Newton R, Beerli C, Mercer J, Gerber C, Müller DJ.

Nature. 2017 Oct 25;550(7677):500-505. doi: 10.1038/nature24288.

PMID:
29072271
21.

Combining confocal and atomic force microscopy to quantify single-virus binding to mammalian cell surfaces.

Newton R, Delguste M, Koehler M, Dumitru AC, Laskowski PR, Müller DJ, Alsteens D.

Nat Protoc. 2017 Nov;12(11):2275-2292. doi: 10.1038/nprot.2017.112. Epub 2017 Oct 5.

PMID:
28981124
22.

C-reactive protein and cardiovascular risk in bipolar disorder patients: A systematic review.

Marshe VS, Pira S, Mantere O, Bosche B, Looper KJ, Herrmann N, Müller DJ, Rej S.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Oct 3;79(Pt B):442-451. doi: 10.1016/j.pnpbp.2017.07.026. Epub 2017 Jul 29. Review.

PMID:
28764912
23.

High-Resolution Imaging and Multiparametric Characterization of Native Membranes by Combining Confocal Microscopy and an Atomic Force Microscopy-Based Toolbox.

Laskowski PR, Pfreundschuh M, Stauffer M, Ucurum Z, Fotiadis D, Müller DJ.

ACS Nano. 2017 Aug 22;11(8):8292-8301. doi: 10.1021/acsnano.7b03456. Epub 2017 Aug 1.

PMID:
28745869
24.

Fusion Domains Guide the Oriented Insertion of Light-Driven Proton Pumps into Liposomes.

Ritzmann N, Thoma J, Hirschi S, Kalbermatter D, Fotiadis D, Müller DJ.

Biophys J. 2017 Sep 19;113(6):1181-1186. doi: 10.1016/j.bpj.2017.06.022. Epub 2017 Jul 8.

PMID:
28697898
25.

Genome-wide association studies of placebo and duloxetine response in major depressive disorder.

Maciukiewicz M, Marshe VS, Tiwari AK, Fonseka TM, Freeman N, Kennedy JL, Rotzinger S, Foster JA, Kennedy SH, Müller DJ.

Pharmacogenomics J. 2018 May 22;18(3):406-412. doi: 10.1038/tpj.2017.29. Epub 2017 Jul 11.

PMID:
28696415
26.

A comprehensive analysis of mitochondrial genes variants and their association with antipsychotic-induced weight gain.

Mittal K, Gonçalves VF, Harripaul R, Cuperfain AB, Rollins B, Tiwari AK, Zai CC, Maciukiewicz M, Müller DJ, Vawter MP, Kennedy JL.

Schizophr Res. 2017 Sep;187:67-73. doi: 10.1016/j.schres.2017.06.046. Epub 2017 Jul 8.

27.

Pull-and-Paste of Single Transmembrane Proteins.

Serdiuk T, Mari SA, Müller DJ.

Nano Lett. 2017 Jul 12;17(7):4478-4488. doi: 10.1021/acs.nanolett.7b01844. Epub 2017 Jun 23.

PMID:
28627175
28.

Maltoporin LamB Unfolds β Hairpins along Mechanical Stress-Dependent Unfolding Pathways.

Thoma J, Ritzmann N, Wolf D, Mulvihill E, Hiller S, Müller DJ.

Structure. 2017 Jul 5;25(7):1139-1144.e2. doi: 10.1016/j.str.2017.05.010. Epub 2017 Jun 15.

PMID:
28625789
29.

The microbiome-gut-brain axis: implications for schizophrenia and antipsychotic induced weight gain.

Kanji S, Fonseka TM, Marshe VS, Sriretnakumar V, Hahn MK, Müller DJ.

Eur Arch Psychiatry Clin Neurosci. 2018 Feb;268(1):3-15. doi: 10.1007/s00406-017-0820-z. Epub 2017 Jun 17. Review.

PMID:
28624847
30.

Association Study of Serotonin 3 Receptor Subunit Gene Variants in Antipsychotic-Induced Weight Gain.

Zai CC, Tiwari AK, Chowdhury NI, Brandl EJ, Shaikh SA, Freeman N, Lieberman JA, Meltzer HY, Kennedy JL, Müller DJ.

Neuropsychobiology. 2016;74(3):169-175. doi: 10.1159/000457903. Epub 2017 May 23.

31.

MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes.

Lopez JP, Fiori LM, Cruceanu C, Lin R, Labonte B, Cates HM, Heller EA, Vialou V, Ku SM, Gerald C, Han MH, Foster J, Frey BN, Soares CN, Müller DJ, Farzan F, Leri F, MacQueen GM, Feilotter H, Tyryshkin K, Evans KR, Giacobbe P, Blier P, Lam RW, Milev R, Parikh SV, Rotzinger S, Strother SC, Lewis CM, Aitchison KJ, Wittenberg GM, Mechawar N, Nestler EJ, Uher R, Kennedy SH, Turecki G.

Nat Commun. 2017 May 22;8:15497. doi: 10.1038/ncomms15497.

32.

Cognitive and psychosocial function in retired professional hockey players.

Esopenko C, Chow TW, Tartaglia MC, Bacopulos A, Kumar P, Binns MA, Kennedy JL, Müller DJ, Levine B.

J Neurol Neurosurg Psychiatry. 2017 Jun;88(6):512-519. doi: 10.1136/jnnp-2016-315260. Epub 2017 Apr 10.

PMID:
28396361
33.

Genetic study of neuregulin 1 and receptor tyrosine-protein kinase erbB-4 in tardive dyskinesia.

Zai CC, Tiwari AK, Chowdhury NI, Yilmaz Z, de Luca V, Müller DJ, Potkin SG, Lieberman JA, Meltzer HY, Voineskos AN, Remington G, Kennedy JL.

World J Biol Psychiatry. 2017 Apr 10:1-5. doi: 10.1080/15622975.2017.1301681. [Epub ahead of print]

PMID:
28394697
34.

Imaging modes of atomic force microscopy for application in molecular and cell biology.

Dufrêne YF, Ando T, Garcia R, Alsteens D, Martinez-Martin D, Engel A, Gerber C, Müller DJ.

Nat Nanotechnol. 2017 Apr 6;12(4):295-307. doi: 10.1038/nnano.2017.45. Review.

PMID:
28383040
35.

Detecting Ligand-Binding Events and Free Energy Landscape while Imaging Membrane Receptors at Subnanometer Resolution.

Pfreundschuh M, Harder D, Ucurum Z, Fotiadis D, Müller DJ.

Nano Lett. 2017 May 10;17(5):3261-3269. doi: 10.1021/acs.nanolett.7b00941. Epub 2017 Apr 5.

PMID:
28361535
36.

Multiparametric Atomic Force Microscopy Imaging of Biomolecular and Cellular Systems.

Alsteens D, Müller DJ, Dufrêne YF.

Acc Chem Res. 2017 Apr 18;50(4):924-931. doi: 10.1021/acs.accounts.6b00638. Epub 2017 Mar 28.

PMID:
28350161
37.

Pharmacogenetic Analysis of Functional Glutamate System Gene Variants and Clinical Response to Clozapine.

Taylor DL, Tiwari AK, Lieberman JA, Potkin SG, Meltzer HY, Knight J, Remington G, Müller DJ, Kennedy JL.

Mol Neuropsychiatry. 2017 Feb;2(4):185-197. doi: 10.1159/000449224. Epub 2016 Oct 12.

38.

Membrane proteins scrambling through a folding landscape.

Müller DJ, Gaub HE.

Science. 2017 Mar 3;355(6328):907-908. doi: 10.1126/science.aam8370. No abstract available.

PMID:
28254899
39.

Mechanical Stimulation of Piezo1 Receptors Depends on Extracellular Matrix Proteins and Directionality of Force.

Gaub BM, Müller DJ.

Nano Lett. 2017 Mar 8;17(3):2064-2072. doi: 10.1021/acs.nanolett.7b00177. Epub 2017 Feb 8.

PMID:
28164706
40.

αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin.

Bharadwaj M, Strohmeyer N, Colo GP, Helenius J, Beerenwinkel N, Schiller HB, Fässler R, Müller DJ.

Nat Commun. 2017 Jan 27;8:14348. doi: 10.1038/ncomms14348.

41.

Association study between the neurexin-1 gene and tardive dyskinesia.

Lanning R, Lett TA, Tiwari AK, Brandl EJ, de Luca V, Voineskos AN, Potkin SG, Lieberman JA, Meltzer HY, Müller DJ, Remington G, Kennedy JL, Zai CC.

Hum Psychopharmacol. 2017 Jan;32(1). doi: 10.1002/hup.2568.

PMID:
28120489
42.

The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes.

Benito-Jardón M, Klapproth S, Gimeno-LLuch I, Petzold T, Bharadwaj M, Müller DJ, Zuchtriegel G, Reichel CA, Costell M.

Elife. 2017 Jan 16;6. pii: e22264. doi: 10.7554/eLife.22264.

43.

Norepinephrine Transporter Gene Variants and Remission From Depression With Venlafaxine Treatment in Older Adults.

Marshe VS, Maciukiewicz M, Rej S, Tiwari AK, Sibille E, Blumberger DM, Karp JF, Lenze EJ, Reynolds CF 3rd, Kennedy JL, Mulsant BH, Müller DJ.

Am J Psychiatry. 2017 May 1;174(5):468-475. doi: 10.1176/appi.ajp.2016.16050617. Epub 2017 Jan 10.

PMID:
28068779
44.

Childhood Abuse History in Depression Predicts Better Response to Antidepressants with Higher Serotonin Transporter Affinity: A Pilot Investigation.

Quilty LC, Marshe V, Lobo DS, Harkness KL, Müller DJ, Bagby RM.

Neuropsychobiology. 2016;74(2):78-83. doi: 10.1159/000453549. Epub 2017 Jan 7.

PMID:
28064281
45.

Special issue: Biomolecular forces.

Rief M, Müller DJ.

J Struct Biol. 2017 Jan;197(1):1-2. doi: 10.1016/j.jsb.2016.12.008. No abstract available.

PMID:
28061956
46.

Low-Dose Lithium Stabilizes Human Endothelial Barrier by Decreasing MLC Phosphorylation and Universally Augments Cholinergic Vasorelaxation Capacity in a Direct Manner.

Bosche B, Molcanyi M, Rej S, Doeppner TR, Obermann M, Müller DJ, Das A, Hescheler J, Macdonald RL, Noll T, Härtel FV.

Front Physiol. 2016 Dec 6;7:593. doi: 10.3389/fphys.2016.00593. eCollection 2016.

47.

Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update.

Hicks JK, Sangkuhl K, Swen JJ, Ellingrod VL, Müller DJ, Shimoda K, Bishop JR, Kharasch ED, Skaar TC, Gaedigk A, Dunnenberger HM, Klein TE, Caudle KE, Stingl JC.

Clin Pharmacol Ther. 2016 Dec 20. doi: 10.1002/cpt.597. [Epub ahead of print] No abstract available.

48.

The biomechanical properties of an epithelial tissue determine the location of its vasculature.

Kragl M, Schubert R, Karsjens H, Otter S, Bartosinska B, Jeruschke K, Weiss J, Chen C, Alsteens D, Kuss O, Speier S, Eberhard D, Müller DJ, Lammert E.

Nat Commun. 2016 Dec 20;7:13560. doi: 10.1038/ncomms13560.

49.

Mechanism of allosteric regulation of β2-adrenergic receptor by cholesterol.

Manna M, Niemelä M, Tynkkynen J, Javanainen M, Kulig W, Müller DJ, Rog T, Vattulainen I.

Elife. 2016 Nov 29;5. pii: e18432. doi: 10.7554/eLife.18432.

50.

Impact of histamine receptors H1 and H3 polymorphisms on antipsychotic-induced weight gain.

Tiwari AK, Zhang D, Pouget JG, Zai CC, Chowdhury NI, Brandl EJ, Qin L, Freeman N, Lieberman JA, Meltzer HY, Kennedy JL, Müller DJ.

World J Biol Psychiatry. 2016 Dec 15:1-9. doi: 10.1080/15622975.2016.1262061. [Epub ahead of print]

PMID:
27855565

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