Format
Sort by
Items per page

Send to

Choose Destination

Best matches for Müller CE[au]:

Anthraquinones As Pharmacological Tools and Drugs. Malik EM et al. Med Res Rev. (2016)

Medicinal chemistry of adenosine, P2Y and P2X receptors. Jacobson KA et al. Neuropharmacology. (2016)

Age-related shift in LTD is dependent on neuronal adenosine A<sub>2A</sub> receptors interplay with mGluR5 and NMDA receptors. Temido-Ferreira M et al. Mol Psychiatry. (2018)

Search results

Items: 1 to 50 of 414

1.

2-Substituted α,β Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.

Bhattarai S, Pippel J, Scaletti ER, Idris R, Freundlieb M, Rolshoven G, Renn C, Lee SY, Abdelrahman A, Zimmermann H, El-Tayeb A, Müller CE, Sträter N.

J Med Chem. 2020 Feb 11. doi: 10.1021/acs.jmedchem.9b01611. [Epub ahead of print]

PMID:
32045236
2.

Update of P2Y Receptor Pharmacology: IUPHAR Review:27.

Jacobson KA, Delicado EG, Gachet C, Kennedy C, von Kügelgen I, Li B, Miras-Portugal MT, Novak I, Schöneberg T, Perez-Sen R, Thor D, Wu B, Yang Z, Müller CE.

Br J Pharmacol. 2020 Feb 9. doi: 10.1111/bph.15005. [Epub ahead of print] Review.

PMID:
32037507
3.

Synthesis of Novel Potent Archazolids: Pharmacology of an Emerging Class of Anticancer Drugs.

Scheeff S, Rivière S, Ruiz J, Abdelrahman A, Schulz-Fincke AC, Köse M, Tiburcy F, Wieczorek H, Gütschow M, Müller CE, Menche D.

J Med Chem. 2020 Feb 13. doi: 10.1021/acs.jmedchem.9b01887. [Epub ahead of print]

PMID:
31990540
4.

Differential Defecation of Solid and Liquid Phases in Horses-A Descriptive Survey.

Lindroth KM, Johansen A, Båverud V, Dicksved J, Lindberg JE, Müller CE.

Animals (Basel). 2020 Jan 1;10(1). pii: E76. doi: 10.3390/ani10010076.

5.

Chromenones as Multineurotargeting Inhibitors of Human Enzymes.

Lemke C, Christmann J, Yin J, Alonso JM, Serrano E, Chioua M, Ismaili L, Martínez-Grau MA, Beadle CD, Vetman T, Dato FM, Bartz U, Elsinghorst PW, Pietsch M, Müller CE, Iriepa I, Wille T, Marco-Contelles J, Gütschow M.

ACS Omega. 2019 Dec 11;4(26):22161-22168. doi: 10.1021/acsomega.9b03409. eCollection 2019 Dec 24.

6.

Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.

Kuschak M, Namasivayam V, Rafehi M, Voss JH, Garg J, Schlegel JG, Abdelrahman A, Kehraus S, Reher R, Küppers J, Sylvester K, Hinz S, Matthey M, Wenzel D, Fleischmann BK, Pfeifer A, Inoue A, Gütschow M, König GM, Müller CE.

Br J Pharmacol. 2019 Dec 27. doi: 10.1111/bph.14960. [Epub ahead of print]

PMID:
31881095
7.

Ligand binding and activation of UTP-activated G protein-coupled P2Y2 and P2Y4 receptors elucidated by mutagenesis, pharmacological and computational studies.

Attah IY, Neumann A, Al-Hroub H, Rafehi M, Baqi Y, Namasivayam V, Müller CE.

Biochim Biophys Acta Gen Subj. 2020 Mar;1864(3):129501. doi: 10.1016/j.bbagen.2019.129501. Epub 2019 Dec 5.

PMID:
31812541
8.

Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists.

Claff T, Yu J, Blais V, Patel N, Martin C, Wu L, Han GW, Holleran BJ, Van der Poorten O, White KL, Hanson MA, Sarret P, Gendron L, Cherezov V, Katritch V, Ballet S, Liu ZJ, Müller CE, Stevens RC.

Sci Adv. 2019 Nov 27;5(11):eaax9115. doi: 10.1126/sciadv.aax9115. eCollection 2019 Nov.

9.

Substituted 4-phenylthiazoles: Development of potent and selective A1, A3 and dual A1/A3 adenosine receptor antagonists.

Abdelrahman A, Yerande SG, Namasivayam V, Klapschinski TA, Alnouri MW, El-Tayeb A, Müller CE.

Eur J Med Chem. 2020 Jan 15;186:111879. doi: 10.1016/j.ejmech.2019.111879. Epub 2019 Nov 15.

PMID:
31780082
10.

A2A and A2B adenosine receptors: The extracellular loop 2 determines high (A2A) or low affinity (A2B) for adenosine.

De Filippo E, Hinz S, Pellizzari V, Deganutti G, El-Tayeb A, Navarro G, Franco R, Moro S, Schiedel AC, Müller CE.

Biochem Pharmacol. 2020 Feb;172:113718. doi: 10.1016/j.bcp.2019.113718. Epub 2019 Nov 18.

PMID:
31751537
11.

Design, synthesis and biological evaluation of suramin-derived dual antagonists of the proinflammatory G protein-coupled receptors P2Y2 and GPR17.

Pillaiyar T, Funke M, Al-Hroub H, Weyler S, Ivanova S, Schlegel J, Abdelrahman A, Müller CE.

Eur J Med Chem. 2020 Jan 15;186:111789. doi: 10.1016/j.ejmech.2019.111789. Epub 2019 Oct 18.

PMID:
31727469
12.

An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights.

Köse M, Pillaiyar T, Namasivayam V, De Filippo E, Sylvester K, Ulven T, von Kügelgen I, Müller CE.

J Med Chem. 2019 Nov 27. doi: 10.1021/acs.jmedchem.9b01339. [Epub ahead of print]

PMID:
31721581
13.

Adenine-(methoxy)-ethoxy-Pα,α-dithio-triphosphate inhibits pathologic calcium pyrophosphate deposition in osteoarthritic human chondrocytes.

Nassir M, Mirza S, Arad U, Lee S, Rafehi M, Yaw Attah I, Renn C, Zimmermann H, Pelletier J, Sévigny J, Müller CE, Fischer B.

Org Biomol Chem. 2019 Nov 27;17(46):9913-9923. doi: 10.1039/c9ob02199j.

PMID:
31720670
14.

Agonists and Antagonists for Purinergic Receptors.

Müller CE, Baqi Y, Namasivayam V.

Methods Mol Biol. 2020;2041:45-64. doi: 10.1007/978-1-4939-9717-6_3.

PMID:
31646479
15.

Ultrasonographic study of the temporomandibular joint in individuals with and without temporomandibular disorder.

Díaz DZR, Müller CEE, Gavião MBD.

J Oral Sci. 2019 Nov 27;61(4):539-543. doi: 10.2334/josnusd.18-0278. Epub 2019 Oct 5.

16.

Caffeine modulates voluntary alcohol intake in mice depending on the access conditions: Involvement of adenosine receptors and the role of individual differences.

SanMiguel N, López-Cruz L, Müller CE, Salamone JD, Correa M.

Pharmacol Biochem Behav. 2019 Nov;186:172789. doi: 10.1016/j.pbb.2019.172789. Epub 2019 Sep 6.

PMID:
31499144
17.

Identification of aurintricarboxylic acid as a potent allosteric antagonist of P2X1 and P2X3 receptors.

Obrecht AS, Urban N, Schaefer M, Röse A, Kless A, Meents JE, Lampert A, Abdelrahman A, Müller CE, Schmalzing G, Hausmann R.

Neuropharmacology. 2019 Nov 1;158:107749. doi: 10.1016/j.neuropharm.2019.107749. Epub 2019 Aug 25.

PMID:
31461640
18.

Editor's Choice- Impact of identifying precipitating factors on 30-day mortality in acute heart failure patients.

Rossello X, Gil V, Escoda R, Jacob J, Aguirre A, Martín-Sánchez FJ, Llorens P, Herrero Puente P, Rizzi M, Raposeiras-Roubín S, Wussler D, Müller CE, Gayat E, Mebazaa A, Miró Ò; ICA-SEMES Research Group.

Eur Heart J Acute Cardiovasc Care. 2019 Oct;8(7):667-680. doi: 10.1177/2048872619869328. Epub 2019 Aug 22.

PMID:
31436133
19.

Departments involved during the first episode of acute heart failure and subsequent emergency department revisits and rehospitalisations: an outlook through the NOVICA cohort.

Miró Ò, García Sarasola A, Fuenzalida C, Calderón S, Jacob J, Aguirre A, Wu DM, Rizzi MA, Malchair P, Haro A, Herrera S, Gil V, Martín-Sánchez FJ, Llorens P, Herrero Puente P, Bueno H, Domínguez Rodríguez A, Müller CE, Mebazaa A, Chioncel O, Alquézar-Arbé A; ICA-SEMES Research Group.

Eur J Heart Fail. 2019 Oct;21(10):1231-1244. doi: 10.1002/ejhf.1567. Epub 2019 Aug 7.

PMID:
31389111
20.

Correction to: Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes.

Nassir M, Arad U, Lee SY, Journo S, Renn SMC, Zimmermann H, Pelletier J, Sévigny J, Müller CE, Fischer B.

Purinergic Signal. 2019 Sep;15(3):421. doi: 10.1007/s11302-019-09671-4.

21.

Structural and Conformational Studies on Carboxamides of 5,6-Diaminouracils-Precursors of Biologically Active Xanthine Derivatives.

Marx D, Schnakenburg G, Grimme S, Müller CE.

Molecules. 2019 Jun 9;24(11). pii: E2168. doi: 10.3390/molecules24112168.

22.

[Progress in cannabis research from a pharmaceutical chemist's point of view].

Müller CE.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2019 Jul;62(7):818-824. doi: 10.1007/s00103-019-02964-4. Review. German.

PMID:
31161229
23.

Memory deficits induced by chronic cannabinoid exposure are prevented by adenosine A2AR receptor antagonism.

Mouro FM, Köfalvi A, André LA, Baqi Y, Müller CE, Ribeiro JA, Sebastião AM.

Neuropharmacology. 2019 Sep 1;155:10-21. doi: 10.1016/j.neuropharm.2019.05.003. Epub 2019 May 16.

24.

Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes.

Nassir M, Arad U, Lee SY, Journo S, Mirza S, Renn C, Zimmermann H, Pelletier J, Sévigny J, Müller CE, Fischer B.

Purinergic Signal. 2019 Jun;15(2):247-263. doi: 10.1007/s11302-019-09649-2. Epub 2019 Apr 25. Erratum in: Purinergic Signal. 2019 Jul 20;:.

25.

Investigation on 2',3'-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists.

Dal Ben D, Buccioni M, Lambertucci C, Marucci G, Spinaci A, Marchenkova A, Abdelrahman A, Nistri A, Müller CE, Volpini R.

ACS Med Chem Lett. 2018 Dec 26;10(4):493-498. doi: 10.1021/acsmedchemlett.8b00524. eCollection 2019 Apr 11.

PMID:
30996785
26.

Coordination of capsule assembly and cell wall biosynthesis in Staphylococcus aureus.

Rausch M, Deisinger JP, Ulm H, Müller A, Li W, Hardt P, Wang X, Li X, Sylvester M, Engeser M, Vollmer W, Müller CE, Sahl HG, Lee JC, Schneider T.

Nat Commun. 2019 Mar 29;10(1):1404. doi: 10.1038/s41467-019-09356-x.

27.

Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors.

Junker A, Renn C, Dobelmann C, Namasivayam V, Jain S, Losenkova K, Irjala H, Duca S, Balasubramanian R, Chakraborty S, Börgel F, Zimmermann H, Yegutkin GG, Müller CE, Jacobson KA.

J Med Chem. 2019 Apr 11;62(7):3677-3695. doi: 10.1021/acs.jmedchem.9b00164. Epub 2019 Mar 21.

PMID:
30895781
28.

A2B Adenosine Receptor Antagonists with Picomolar Potency.

Jiang J, Seel CJ, Temirak A, Namasivayam V, Arridu A, Schabikowski J, Baqi Y, Hinz S, Hockemeyer J, Müller CE.

J Med Chem. 2019 Apr 25;62(8):4032-4055. doi: 10.1021/acs.jmedchem.9b00071. Epub 2019 Apr 15.

PMID:
30835463
29.

Fast, Efficient, and Versatile Synthesis of 6-amino-5-carboxamidouracils as Precursors for 8-Substituted Xanthines.

Marx D, Wingen LM, Schnakenburg G, Müller CE, Scholz MS.

Front Chem. 2019 Feb 18;7:56. doi: 10.3389/fchem.2019.00056. eCollection 2019.

30.

Novel multi-target directed ligands based on annelated xanthine scaffold with aromatic substituents acting on adenosine receptor and monoamine oxidase B. Synthesis, in vitro and in silico studies.

Załuski M, Schabikowski J, Schlenk M, Olejarz-Maciej A, Kubas B, Karcz T, Kuder K, Latacz G, Zygmunt M, Synak D, Hinz S, Müller CE, Kieć-Kononowicz K.

Bioorg Med Chem. 2019 Apr 1;27(7):1195-1210. doi: 10.1016/j.bmc.2019.02.004. Epub 2019 Feb 2.

PMID:
30808606
31.

Modulating P1 Adenosine Receptors in Disease Progression of SOD1G93A Mutant Mice.

Armida M, Matteucci A, Pèzzola A, Baqi Y, Müller CE, Popoli P, Potenza RL.

Neurochem Res. 2019 May;44(5):1037-1042. doi: 10.1007/s11064-019-02745-0. Epub 2019 Feb 12.

PMID:
30756215
32.

Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage.

Zeiner J, Loukovaara S, Losenkova K, Zuccarini M, Korhonen AM, Lehti K, Kauppinen A, Kaarniranta K, Müller CE, Jalkanen S, Yegutkin GG.

J Mol Med (Berl). 2019 Mar;97(3):341-354. doi: 10.1007/s00109-018-01734-0. Epub 2019 Jan 7.

33.

Koala and Wombat Gammaherpesviruses Encode the First Known Viral NTPDase Homologs and Are Phylogenetically Divergent from All Known Gammaherpesviruses.

Vaz PK, Hartley CA, Lee SY, Sansom FM, Adams TE, Stalder K, Pearce L, Lovrecz G, Browning GF, Müller CE, Devlin JM.

J Virol. 2019 Mar 5;93(6). pii: e01404-18. doi: 10.1128/JVI.01404-18. Print 2019 Mar 15.

34.

Diabetes-induced Neuropathic Mechanical Hyperalgesia Depends on P2X4 Receptor Activation in Dorsal Root Ganglia.

Teixeira JM, Dos Santos GG, Neves AF, Athie MCP, Bonet IJM, Nishijima CM, Farias FH, Figueiredo JG, Hernandez-Olmos V, Alshaibani S, Tambeli CH, Müller CE, Parada CA.

Neuroscience. 2019 Feb 1;398:158-170. doi: 10.1016/j.neuroscience.2018.12.003. Epub 2018 Dec 8.

PMID:
30537520
35.

Development of a selective and highly sensitive fluorescence assay for nucleoside triphosphate diphosphohydrolase1 (NTPDase1, CD39).

Lee SY, Luo X, Namasivayam V, Geiss J, Mirza S, Pelletier J, Stephan H, Sévigny J, Müller CE.

Analyst. 2018 Nov 5;143(22):5417-5430. doi: 10.1039/c8an01108g.

PMID:
30303204
36.

Cyclopropane-Containing Fatty Acids from the Marine Bacterium Labrenzia sp. 011 with Antimicrobial and GPR84 Activity.

Amiri Moghaddam J, Dávila-Céspedes A, Kehraus S, Crüsemann M, Köse M, Müller CE, König GM.

Mar Drugs. 2018 Oct 8;16(10). pii: E369. doi: 10.3390/md16100369.

37.

The role of triage to reduce waiting times in primary health care facilities in the North West province of South Africa.

Swart AT, Muller CE, Rabie T.

Health SA. 2018 Oct 10;23:1097. doi: 10.4102/hsag.v23i0.1097. eCollection 2018.

38.

Evaluating the Integrated Management of Childhood Illness counselling skills of professional nurses in the North West Province of South Africa.

Malan MF, Rabie T, Muller CE.

Health SA. 2018 Oct 10;23:1074. doi: 10.4102/hsag.v23i0.1074. eCollection 2018.

39.

Antithrombotic P2Y12 receptor antagonists: recent developments in drug discovery.

Baqi Y, Müller CE.

Drug Discov Today. 2019 Jan;24(1):325-333. doi: 10.1016/j.drudis.2018.09.021. Epub 2018 Oct 3. Review.

PMID:
30291899
40.

Tricyclic xanthine derivatives containing a basic substituent: adenosine receptor affinity and drug-related properties.

Załuski M, Stanuch K, Karcz T, Hinz S, Latacz G, Szymańska E, Schabikowski J, Doroż-Płonka A, Handzlik J, Drabczyńska A, Müller CE, Kieć-Kononowicz K.

Medchemcomm. 2018 May 14;9(6):951-962. doi: 10.1039/c8md00070k. eCollection 2018 Jun 1.

41.

Radiosynthesis and in vivo evaluation of a fluorine-18 labeled pyrazine based radioligand for PET imaging of the adenosine A2B receptor.

Lindemann M, Hinz S, Deuther-Conrad W, Namasivayam V, Dukic-Stefanovic S, Teodoro R, Toussaint M, Kranz M, Juhl C, Steinbach J, Brust P, Müller CE, Wenzel B.

Bioorg Med Chem. 2018 Sep 1;26(16):4650-4663. doi: 10.1016/j.bmc.2018.07.045. Epub 2018 Jul 29.

PMID:
30104122
42.

Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer's Disease.

Faivre E, Coelho JE, Zornbach K, Malik E, Baqi Y, Schneider M, Cellai L, Carvalho K, Sebda S, Figeac M, Eddarkaoui S, Caillierez R, Chern Y, Heneka M, Sergeant N, Müller CE, Halle A, Buée L, Lopes LV, Blum D.

Front Mol Neurosci. 2018 Jul 12;11:235. doi: 10.3389/fnmol.2018.00235. eCollection 2018.

43.

3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17.

Baqi Y, Pillaiyar T, Abdelrahman A, Kaufmann O, Alshaibani S, Rafehi M, Ghasimi S, Akkari R, Ritter K, Simon K, Spinrath A, Kostenis E, Zhao Q, Köse M, Namasivayam V, Müller CE.

J Med Chem. 2018 Sep 27;61(18):8136-8154. doi: 10.1021/acs.jmedchem.7b01768. Epub 2018 Sep 5.

PMID:
30048589
44.

General Synthesis of Unsymmetrical 3,3'-(Aza)diindolylmethane Derivatives.

Pillaiyar T, Gorska E, Schnakenburg G, Müller CE.

J Org Chem. 2018 Sep 7;83(17):9902-9913. doi: 10.1021/acs.joc.8b01349. Epub 2018 Jul 31.

PMID:
30025207
45.

6-(Ar)Alkylamino-Substituted Uracil Derivatives: Lipid Mimetics with Potent Activity at the Orphan G Protein-Coupled Receptor 84 (GPR84).

Pillaiyar T, Köse M, Namasivayam V, Sylvester K, Borges G, Thimm D, von Kügelgen I, Müller CE.

ACS Omega. 2018 Mar 31;3(3):3365-3383. doi: 10.1021/acsomega.7b02092. Epub 2018 Mar 20.

46.

Extracellular adenosine reversibly inhibits the activation of human regulatory T cells and negatively influences the achievement of the operational tolerance in liver transplantation.

Baroja-Mazo A, Revilla-Nuin B, de Bejar Á, Martínez-Alarcón L, Herrero JI, El-Tayeb A, Müller CE, Aparicio P, Pelegrín P, Pons JA.

Am J Transplant. 2019 Jan;19(1):48-61. doi: 10.1111/ajt.15023. Epub 2018 Aug 31.

47.

Probing Substituents in the 1- and 3-Position: Tetrahydropyrazino-Annelated Water-Soluble Xanthine Derivatives as Multi-Target Drugs With Potent Adenosine Receptor Antagonistic Activity.

Koch P, Brunschweiger A, Namasivayam V, Ullrich S, Maruca A, Lazzaretto B, Küppers P, Hinz S, Hockemeyer J, Wiese M, Heer J, Alcaro S, Kiec-Kononowicz K, Müller CE.

Front Chem. 2018 Jun 26;6:206. doi: 10.3389/fchem.2018.00206. eCollection 2018.

48.

Pharmacological evaluation of new constituents of "Spice": synthetic cannabinoids based on indole, indazole, benzimidazole and carbazole scaffolds.

Schoeder CT, Hess C, Madea B, Meiler J, Müller CE.

Forensic Toxicol. 2018;36(2):385-403. doi: 10.1007/s11419-018-0415-z. Epub 2018 Apr 26.

49.

Age-related shift in LTD is dependent on neuronal adenosine A2A receptors interplay with mGluR5 and NMDA receptors.

Temido-Ferreira M, Ferreira DG, Batalha VL, Marques-Morgado I, Coelho JE, Pereira P, Gomes R, Pinto A, Carvalho S, Canas PM, Cuvelier L, Buée-Scherrer V, Faivre E, Baqi Y, Müller CE, Pimentel J, Schiffmann SN, Buée L, Bader M, Outeiro TF, Blum D, Cunha RA, Marie H, Pousinha PA, Lopes LV.

Mol Psychiatry. 2018 Jun 27. doi: 10.1038/s41380-018-0110-9. [Epub ahead of print]

PMID:
29950682
50.

Applying Molecular Networking for the Detection of Natural Sources and Analogues of the Selective Gq Protein Inhibitor FR900359.

Reher R, Kuschak M, Heycke N, Annala S, Kehraus S, Dai HF, Müller CE, Kostenis E, König GM, Crüsemann M.

J Nat Prod. 2018 Jul 27;81(7):1628-1635. doi: 10.1021/acs.jnatprod.8b00222. Epub 2018 Jun 26.

PMID:
29943987

Supplemental Content

Loading ...
Support Center