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Best matches for Müller CE[au]:

Anthraquinones As Pharmacological Tools and Drugs. Malik EM et al. Med Res Rev. (2016)

Medicinal chemistry of adenosine, P2Y and P2X receptors. Jacobson KA et al. Neuropharmacology. (2016)

The experimental power of FR900359 to study Gq-regulated biological processes. Schrage R et al. Nat Commun. (2015)

Search results

Items: 1 to 50 of 405

1.

Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists.

Claff T, Yu J, Blais V, Patel N, Martin C, Wu L, Han GW, Holleran BJ, Van der Poorten O, White KL, Hanson MA, Sarret P, Gendron L, Cherezov V, Katritch V, Ballet S, Liu ZJ, Müller CE, Stevens RC.

Sci Adv. 2019 Nov 27;5(11):eaax9115. doi: 10.1126/sciadv.aax9115. eCollection 2019 Nov.

PMID:
31807708
2.

Substituted 4-phenylthiazoles: Development of potent and selective A1, A3 and dual A1/A3 adenosine receptor antagonists.

Abdelrahman A, Yerande SG, Namasivayam V, Klapschinski TA, Alnouri MW, El-Tayeb A, Müller CE.

Eur J Med Chem. 2019 Nov 15:111879. doi: 10.1016/j.ejmech.2019.111879. [Epub ahead of print]

PMID:
31780082
3.

A2A and A2B adenosine receptors: The extracellular loop 2 determines high (A2A) or low affinity (A2B) for adenosine.

De Filippo E, Hinz S, Pellizzari V, Deganutti G, El-Tayeb A, Navarro G, Franco R, Moro S, Schiedel AC, Müller CE.

Biochem Pharmacol. 2019 Nov 18;172:113718. doi: 10.1016/j.bcp.2019.113718. [Epub ahead of print]

PMID:
31751537
4.

Design, synthesis and biological evaluation of suramin-derived dual antagonists of the proinflammatory G protein-coupled receptors P2Y2 and GPR17.

Pillaiyar T, Funke M, Al-Hroub H, Weyler S, Ivanova S, Schlegel J, Abdelrahman A, Müller CE.

Eur J Med Chem. 2019 Oct 18:111789. doi: 10.1016/j.ejmech.2019.111789. [Epub ahead of print]

PMID:
31727469
5.

An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights.

Köse M, Pillaiyar T, Namasivayam V, De Filippo E, Sylvester K, Ulven T, von Kügelgen I, Müller CE.

J Med Chem. 2019 Nov 27. doi: 10.1021/acs.jmedchem.9b01339. [Epub ahead of print]

PMID:
31721581
6.

Adenine-(methoxy)-ethoxy-Pα,α-dithio-triphosphate inhibits pathologic calcium pyrophosphate deposition in osteoarthritic human chondrocytes.

Nassir M, Mirza S, Arad U, Lee S, Rafehi M, Yaw Attah I, Renn C, Zimmermann H, Pelletier J, Sévigny J, Müller CE, Fischer B.

Org Biomol Chem. 2019 Nov 27;17(46):9913-9923. doi: 10.1039/c9ob02199j.

PMID:
31720670
7.

Agonists and Antagonists for Purinergic Receptors.

Müller CE, Baqi Y, Namasivayam V.

Methods Mol Biol. 2020;2041:45-64. doi: 10.1007/978-1-4939-9717-6_3.

PMID:
31646479
8.

Ultrasonographic study of the temporomandibular joint in individuals with and without temporomandibular disorder.

Díaz DZR, Müller CEE, Gavião MBD.

J Oral Sci. 2019 Nov 27;61(4):539-543. doi: 10.2334/josnusd.18-0278. Epub 2019 Oct 5.

9.

Caffeine modulates voluntary alcohol intake in mice depending on the access conditions: Involvement of adenosine receptors and the role of individual differences.

SanMiguel N, López-Cruz L, Müller CE, Salamone JD, Correa M.

Pharmacol Biochem Behav. 2019 Nov;186:172789. doi: 10.1016/j.pbb.2019.172789. Epub 2019 Sep 6.

PMID:
31499144
10.

Identification of aurintricarboxylic acid as a potent allosteric antagonist of P2X1 and P2X3 receptors.

Obrecht AS, Urban N, Schaefer M, Röse A, Kless A, Meents JE, Lampert A, Abdelrahman A, Müller CE, Schmalzing G, Hausmann R.

Neuropharmacology. 2019 Nov 1;158:107749. doi: 10.1016/j.neuropharm.2019.107749. Epub 2019 Aug 25.

PMID:
31461640
11.

Editor's Choice- Impact of identifying precipitating factors on 30-day mortality in acute heart failure patients.

Rossello X, Gil V, Escoda R, Jacob J, Aguirre A, Martín-Sánchez FJ, Llorens P, Herrero Puente P, Rizzi M, Raposeiras-Roubín S, Wussler D, Müller CE, Gayat E, Mebazaa A, Miró Ò; ICA-SEMES Research Group.

Eur Heart J Acute Cardiovasc Care. 2019 Oct;8(7):667-680. doi: 10.1177/2048872619869328. Epub 2019 Aug 22.

PMID:
31436133
12.

Departments involved during the first episode of acute heart failure and subsequent emergency department revisits and rehospitalisations: an outlook through the NOVICA cohort.

Miró Ò, García Sarasola A, Fuenzalida C, Calderón S, Jacob J, Aguirre A, Wu DM, Rizzi MA, Malchair P, Haro A, Herrera S, Gil V, Martín-Sánchez FJ, Llorens P, Herrero Puente P, Bueno H, Domínguez Rodríguez A, Müller CE, Mebazaa A, Chioncel O, Alquézar-Arbé A; ICA-SEMES Research Group.

Eur J Heart Fail. 2019 Oct;21(10):1231-1244. doi: 10.1002/ejhf.1567. Epub 2019 Aug 7.

PMID:
31389111
13.

Correction to: Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes.

Nassir M, Arad U, Lee SY, Journo S, Renn SMC, Zimmermann H, Pelletier J, Sévigny J, Müller CE, Fischer B.

Purinergic Signal. 2019 Sep;15(3):421. doi: 10.1007/s11302-019-09671-4.

14.

Structural and Conformational Studies on Carboxamides of 5,6-Diaminouracils-Precursors of Biologically Active Xanthine Derivatives.

Marx D, Schnakenburg G, Grimme S, Müller CE.

Molecules. 2019 Jun 9;24(11). pii: E2168. doi: 10.3390/molecules24112168.

15.

[Progress in cannabis research from a pharmaceutical chemist's point of view].

Müller CE.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2019 Jul;62(7):818-824. doi: 10.1007/s00103-019-02964-4. Review. German.

PMID:
31161229
16.

Memory deficits induced by chronic cannabinoid exposure are prevented by adenosine A2AR receptor antagonism.

Mouro FM, Köfalvi A, André LA, Baqi Y, Müller CE, Ribeiro JA, Sebastião AM.

Neuropharmacology. 2019 Sep 1;155:10-21. doi: 10.1016/j.neuropharm.2019.05.003. Epub 2019 May 16.

17.

Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes.

Nassir M, Arad U, Lee SY, Journo S, Mirza S, Renn C, Zimmermann H, Pelletier J, Sévigny J, Müller CE, Fischer B.

Purinergic Signal. 2019 Jun;15(2):247-263. doi: 10.1007/s11302-019-09649-2. Epub 2019 Apr 25. Erratum in: Purinergic Signal. 2019 Jul 20;:.

18.

Investigation on 2',3'-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists.

Dal Ben D, Buccioni M, Lambertucci C, Marucci G, Spinaci A, Marchenkova A, Abdelrahman A, Nistri A, Müller CE, Volpini R.

ACS Med Chem Lett. 2018 Dec 26;10(4):493-498. doi: 10.1021/acsmedchemlett.8b00524. eCollection 2019 Apr 11.

PMID:
30996785
19.

Coordination of capsule assembly and cell wall biosynthesis in Staphylococcus aureus.

Rausch M, Deisinger JP, Ulm H, Müller A, Li W, Hardt P, Wang X, Li X, Sylvester M, Engeser M, Vollmer W, Müller CE, Sahl HG, Lee JC, Schneider T.

Nat Commun. 2019 Mar 29;10(1):1404. doi: 10.1038/s41467-019-09356-x.

20.

Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors.

Junker A, Renn C, Dobelmann C, Namasivayam V, Jain S, Losenkova K, Irjala H, Duca S, Balasubramanian R, Chakraborty S, Börgel F, Zimmermann H, Yegutkin GG, Müller CE, Jacobson KA.

J Med Chem. 2019 Apr 11;62(7):3677-3695. doi: 10.1021/acs.jmedchem.9b00164. Epub 2019 Mar 21.

PMID:
30895781
21.

A2B Adenosine Receptor Antagonists with Picomolar Potency.

Jiang J, Seel CJ, Temirak A, Namasivayam V, Arridu A, Schabikowski J, Baqi Y, Hinz S, Hockemeyer J, Müller CE.

J Med Chem. 2019 Apr 25;62(8):4032-4055. doi: 10.1021/acs.jmedchem.9b00071. Epub 2019 Apr 15.

PMID:
30835463
22.

Fast, Efficient, and Versatile Synthesis of 6-amino-5-carboxamidouracils as Precursors for 8-Substituted Xanthines.

Marx D, Wingen LM, Schnakenburg G, Müller CE, Scholz MS.

Front Chem. 2019 Feb 18;7:56. doi: 10.3389/fchem.2019.00056. eCollection 2019.

23.

Novel multi-target directed ligands based on annelated xanthine scaffold with aromatic substituents acting on adenosine receptor and monoamine oxidase B. Synthesis, in vitro and in silico studies.

Załuski M, Schabikowski J, Schlenk M, Olejarz-Maciej A, Kubas B, Karcz T, Kuder K, Latacz G, Zygmunt M, Synak D, Hinz S, Müller CE, Kieć-Kononowicz K.

Bioorg Med Chem. 2019 Apr 1;27(7):1195-1210. doi: 10.1016/j.bmc.2019.02.004. Epub 2019 Feb 2.

PMID:
30808606
24.

Modulating P1 Adenosine Receptors in Disease Progression of SOD1G93A Mutant Mice.

Armida M, Matteucci A, Pèzzola A, Baqi Y, Müller CE, Popoli P, Potenza RL.

Neurochem Res. 2019 May;44(5):1037-1042. doi: 10.1007/s11064-019-02745-0. Epub 2019 Feb 12.

PMID:
30756215
25.

Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage.

Zeiner J, Loukovaara S, Losenkova K, Zuccarini M, Korhonen AM, Lehti K, Kauppinen A, Kaarniranta K, Müller CE, Jalkanen S, Yegutkin GG.

J Mol Med (Berl). 2019 Mar;97(3):341-354. doi: 10.1007/s00109-018-01734-0. Epub 2019 Jan 7.

26.

Koala and Wombat Gammaherpesviruses Encode the First Known Viral NTPDase Homologs and Are Phylogenetically Divergent from All Known Gammaherpesviruses.

Vaz PK, Hartley CA, Lee SY, Sansom FM, Adams TE, Stalder K, Pearce L, Lovrecz G, Browning GF, Müller CE, Devlin JM.

J Virol. 2019 Mar 5;93(6). pii: e01404-18. doi: 10.1128/JVI.01404-18. Print 2019 Mar 15.

27.

Diabetes-induced Neuropathic Mechanical Hyperalgesia Depends on P2X4 Receptor Activation in Dorsal Root Ganglia.

Teixeira JM, Dos Santos GG, Neves AF, Athie MCP, Bonet IJM, Nishijima CM, Farias FH, Figueiredo JG, Hernandez-Olmos V, Alshaibani S, Tambeli CH, Müller CE, Parada CA.

Neuroscience. 2019 Feb 1;398:158-170. doi: 10.1016/j.neuroscience.2018.12.003. Epub 2018 Dec 8.

PMID:
30537520
28.

Development of a selective and highly sensitive fluorescence assay for nucleoside triphosphate diphosphohydrolase1 (NTPDase1, CD39).

Lee SY, Luo X, Namasivayam V, Geiss J, Mirza S, Pelletier J, Stephan H, Sévigny J, Müller CE.

Analyst. 2018 Nov 5;143(22):5417-5430. doi: 10.1039/c8an01108g.

PMID:
30303204
29.

Cyclopropane-Containing Fatty Acids from the Marine Bacterium Labrenzia sp. 011 with Antimicrobial and GPR84 Activity.

Amiri Moghaddam J, Dávila-Céspedes A, Kehraus S, Crüsemann M, Köse M, Müller CE, König GM.

Mar Drugs. 2018 Oct 8;16(10). pii: E369. doi: 10.3390/md16100369.

30.

Antithrombotic P2Y12 receptor antagonists: recent developments in drug discovery.

Baqi Y, Müller CE.

Drug Discov Today. 2019 Jan;24(1):325-333. doi: 10.1016/j.drudis.2018.09.021. Epub 2018 Oct 3. Review.

PMID:
30291899
31.

Tricyclic xanthine derivatives containing a basic substituent: adenosine receptor affinity and drug-related properties.

Załuski M, Stanuch K, Karcz T, Hinz S, Latacz G, Szymańska E, Schabikowski J, Doroż-Płonka A, Handzlik J, Drabczyńska A, Müller CE, Kieć-Kononowicz K.

Medchemcomm. 2018 May 14;9(6):951-962. doi: 10.1039/c8md00070k. eCollection 2018 Jun 1.

32.

Radiosynthesis and in vivo evaluation of a fluorine-18 labeled pyrazine based radioligand for PET imaging of the adenosine A2B receptor.

Lindemann M, Hinz S, Deuther-Conrad W, Namasivayam V, Dukic-Stefanovic S, Teodoro R, Toussaint M, Kranz M, Juhl C, Steinbach J, Brust P, Müller CE, Wenzel B.

Bioorg Med Chem. 2018 Sep 1;26(16):4650-4663. doi: 10.1016/j.bmc.2018.07.045. Epub 2018 Jul 29.

PMID:
30104122
33.

Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer's Disease.

Faivre E, Coelho JE, Zornbach K, Malik E, Baqi Y, Schneider M, Cellai L, Carvalho K, Sebda S, Figeac M, Eddarkaoui S, Caillierez R, Chern Y, Heneka M, Sergeant N, Müller CE, Halle A, Buée L, Lopes LV, Blum D.

Front Mol Neurosci. 2018 Jul 12;11:235. doi: 10.3389/fnmol.2018.00235. eCollection 2018.

34.

3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17.

Baqi Y, Pillaiyar T, Abdelrahman A, Kaufmann O, Alshaibani S, Rafehi M, Ghasimi S, Akkari R, Ritter K, Simon K, Spinrath A, Kostenis E, Zhao Q, Köse M, Namasivayam V, Müller CE.

J Med Chem. 2018 Sep 27;61(18):8136-8154. doi: 10.1021/acs.jmedchem.7b01768. Epub 2018 Sep 5.

PMID:
30048589
35.

General Synthesis of Unsymmetrical 3,3'-(Aza)diindolylmethane Derivatives.

Pillaiyar T, Gorska E, Schnakenburg G, Müller CE.

J Org Chem. 2018 Sep 7;83(17):9902-9913. doi: 10.1021/acs.joc.8b01349. Epub 2018 Jul 31.

PMID:
30025207
36.

6-(Ar)Alkylamino-Substituted Uracil Derivatives: Lipid Mimetics with Potent Activity at the Orphan G Protein-Coupled Receptor 84 (GPR84).

Pillaiyar T, Köse M, Namasivayam V, Sylvester K, Borges G, Thimm D, von Kügelgen I, Müller CE.

ACS Omega. 2018 Mar 31;3(3):3365-3383. doi: 10.1021/acsomega.7b02092. Epub 2018 Mar 20.

37.

Extracellular adenosine reversibly inhibits the activation of human regulatory T cells and negatively influences the achievement of the operational tolerance in liver transplantation.

Baroja-Mazo A, Revilla-Nuin B, de Bejar Á, Martínez-Alarcón L, Herrero JI, El-Tayeb A, Müller CE, Aparicio P, Pelegrín P, Pons JA.

Am J Transplant. 2019 Jan;19(1):48-61. doi: 10.1111/ajt.15023. Epub 2018 Aug 31.

PMID:
30019408
38.

Probing Substituents in the 1- and 3-Position: Tetrahydropyrazino-Annelated Water-Soluble Xanthine Derivatives as Multi-Target Drugs With Potent Adenosine Receptor Antagonistic Activity.

Koch P, Brunschweiger A, Namasivayam V, Ullrich S, Maruca A, Lazzaretto B, Küppers P, Hinz S, Hockemeyer J, Wiese M, Heer J, Alcaro S, Kiec-Kononowicz K, Müller CE.

Front Chem. 2018 Jun 26;6:206. doi: 10.3389/fchem.2018.00206. eCollection 2018.

39.

Pharmacological evaluation of new constituents of "Spice": synthetic cannabinoids based on indole, indazole, benzimidazole and carbazole scaffolds.

Schoeder CT, Hess C, Madea B, Meiler J, Müller CE.

Forensic Toxicol. 2018;36(2):385-403. doi: 10.1007/s11419-018-0415-z. Epub 2018 Apr 26.

40.

Age-related shift in LTD is dependent on neuronal adenosine A2A receptors interplay with mGluR5 and NMDA receptors.

Temido-Ferreira M, Ferreira DG, Batalha VL, Marques-Morgado I, Coelho JE, Pereira P, Gomes R, Pinto A, Carvalho S, Canas PM, Cuvelier L, Buée-Scherrer V, Faivre E, Baqi Y, Müller CE, Pimentel J, Schiffmann SN, Buée L, Bader M, Outeiro TF, Blum D, Cunha RA, Marie H, Pousinha PA, Lopes LV.

Mol Psychiatry. 2018 Jun 27. doi: 10.1038/s41380-018-0110-9. [Epub ahead of print]

PMID:
29950682
41.

Applying Molecular Networking for the Detection of Natural Sources and Analogues of the Selective Gq Protein Inhibitor FR900359.

Reher R, Kuschak M, Heycke N, Annala S, Kehraus S, Dai HF, Müller CE, Kostenis E, König GM, Crüsemann M.

J Nat Prod. 2018 Jul 27;81(7):1628-1635. doi: 10.1021/acs.jnatprod.8b00222. Epub 2018 Jun 26.

PMID:
29943987
42.

Structure-activity relationships of imidazothiazinones and analogs as antagonists of the cannabinoid-activated orphan G protein-coupled receptor GPR18.

Schoeder CT, Kaleta M, Mahardhika AB, Olejarz-Maciej A, Łażewska D, Kieć-Kononowicz K, Müller CE.

Eur J Med Chem. 2018 Jul 15;155:381-397. doi: 10.1016/j.ejmech.2018.05.050. Epub 2018 Jun 1.

PMID:
29902723
43.

Molecular and functional interaction between GPR18 and cannabinoid CB2 G-protein-coupled receptors. Relevance in neurodegenerative diseases.

Reyes-Resina I, Navarro G, Aguinaga D, Canela EI, Schoeder CT, Załuski M, Kieć-Kononowicz K, Saura CA, Müller CE, Franco R.

Biochem Pharmacol. 2018 Nov;157:169-179. doi: 10.1016/j.bcp.2018.06.001. Epub 2018 Jun 2.

44.

Tritium-labeled agonists as tools for studying adenosine A2B receptors.

Hinz S, Alnouri WM, Pleiss U, Müller CE.

Purinergic Signal. 2018 Sep;14(3):223-233. doi: 10.1007/s11302-018-9608-5. Epub 2018 May 11.

45.

Time trends in characteristics, clinical course, and outcomes of 13,791 patients with acute heart failure.

Llorens P, Javaloyes P, Martín-Sánchez FJ, Jacob J, Herrero-Puente P, Gil V, Garrido JM, Salvo E, Fuentes M, Alonso H, Richard F, Lucas FJ, Bueno H, Parissis J, Müller CE, Miró Ò; ICA-SEMES Research Group.

Clin Res Cardiol. 2018 Oct;107(10):897-913. doi: 10.1007/s00392-018-1261-z. Epub 2018 May 4.

PMID:
29728831
46.

Fluorescent-Labeled Selective Adenosine A2B Receptor Antagonist Enables Competition Binding Assay by Flow Cytometry.

Köse M, Gollos S, Karcz T, Fiene A, Heisig F, Behrenswerth A, Kieć-Kononowicz K, Namasivayam V, Müller CE.

J Med Chem. 2018 May 24;61(10):4301-4316. doi: 10.1021/acs.jmedchem.7b01627. Epub 2018 May 15.

PMID:
29681156
47.

Mechanism underlying the contractile activity of UTP in the mammalian heart.

Gergs U, Rothkirch D, Hofmann B, Treede H, Robaye B, Simm A, Müller CE, Neumann J.

Eur J Pharmacol. 2018 Jul 5;830:47-58. doi: 10.1016/j.ejphar.2018.04.013. Epub 2018 Apr 17.

PMID:
29673908
48.

Tools and drugs for uracil nucleotide-activated P2Y receptors.

Rafehi M, Müller CE.

Pharmacol Ther. 2018 Oct;190:24-80. doi: 10.1016/j.pharmthera.2018.04.002. Epub 2018 Apr 13. Review.

PMID:
29660366
49.

Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells.

Kwak SH, Shin S, Lee JH, Shim JK, Kim M, Lee SD, Lee A, Bae J, Park JH, Abdelrahman A, Müller CE, Cho SK, Kang SG, Bae MA, Yang JY, Ko H, Goddard WA 3rd, Kim YC.

Eur J Med Chem. 2018 May 10;151:462-481. doi: 10.1016/j.ejmech.2018.03.023. Epub 2018 Mar 9.

PMID:
29649742
50.

Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity.

Poppe D, Doerr J, Schneider M, Wilkens R, Steinbeck JA, Ladewig J, Tam A, Paschon DE, Gregory PD, Reik A, Müller CE, Koch P, Brüstle O.

Stem Cells Transl Med. 2018 Jun;7(6):477-486. doi: 10.1002/sctm.16-0272. Epub 2018 Mar 28.

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