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Items: 21


Activation of the Extracytoplasmic Function σ Factor σP by β-Lactams in Bacillus thuringiensis Requires the Site-2 Protease RasP.

Ho TD, Nauta KM, Müh U, Ellermeier CD.

mSphere. 2019 Aug 7;4(4). pii: e00511-19. doi: 10.1128/mSphere.00511-19.


A Xylose-Inducible Expression System and a CRISPR Interference Plasmid for Targeted Knockdown of Gene Expression in Clostridioides difficile.

Müh U, Pannullo AG, Weiss DS, Ellermeier CD.

J Bacteriol. 2019 Jun 21;201(14). pii: e00711-18. doi: 10.1128/JB.00711-18. Print 2019 Jul 15.


Bacterial sensing: A putative amphipathic helix in RsiV is the switch for activating σV in response to lysozyme.

Lewerke LT, Kies PJ, Müh U, Ellermeier CD.

PLoS Genet. 2018 Jul 18;14(7):e1007527. doi: 10.1371/journal.pgen.1007527. eCollection 2018 Jul.


Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions.

Wang T, Bemis G, Hanzelka B, Zuccola H, Wynn M, Moody CS, Green J, Locher C, Liu A, Gao H, Xu Y, Wang S, Wang J, Bennani YL, Thomson JA, Müh U.

ACS Med Chem Lett. 2017 Nov 28;8(12):1224-1229. doi: 10.1021/acsmedchemlett.7b00239. eCollection 2017 Dec 14.


In vitro phenotypic characterization of hepatitis C virus NS3 protease variants observed in clinical studies of telaprevir.

Jiang M, Mani N, Lin C, Ardzinski A, Nelson M, Reagan D, Bartels D, Zhou Y, Nicolas O, Rao BG, Müh U, Hanzelka B, Tigges A, Rijnbrand R, Kieffer TL.

Antimicrob Agents Chemother. 2013 Dec;57(12):6236-45. doi: 10.1128/AAC.01578-13. Epub 2013 Oct 7.


Phenotypic characterization of resistant Val36 variants of hepatitis C virus NS3-4A serine protease.

Zhou Y, Bartels DJ, Hanzelka BL, Müh U, Wei Y, Chu HM, Tigges AM, Brennan DL, Rao BG, Swenson L, Kwong AD, Lin C.

Antimicrob Agents Chemother. 2008 Jan;52(1):110-20. Epub 2007 Oct 15.


Phenotypic and structural analyses of hepatitis C virus NS3 protease Arg155 variants: sensitivity to telaprevir (VX-950) and interferon alpha.

Zhou Y, Müh U, Hanzelka BL, Bartels DJ, Wei Y, Rao BG, Brennan DL, Tigges AM, Swenson L, Kwong AD, Lin C.

J Biol Chem. 2007 Aug 3;282(31):22619-28. Epub 2007 Jun 6.


Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir.

Sarrazin C, Kieffer TL, Bartels D, Hanzelka B, Müh U, Welker M, Wincheringer D, Zhou Y, Chu HM, Lin C, Weegink C, Reesink H, Zeuzem S, Kwong AD.

Gastroenterology. 2007 May;132(5):1767-77. Epub 2007 Feb 21.


A structurally unrelated mimic of a Pseudomonas aeruginosa acyl-homoserine lactone quorum-sensing signal.

Müh U, Hare BJ, Duerkop BA, Schuster M, Hanzelka BL, Heim R, Olson ER, Greenberg EP.

Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16948-52. Epub 2006 Oct 30.


Novel Pseudomonas aeruginosa quorum-sensing inhibitors identified in an ultra-high-throughput screen.

Müh U, Schuster M, Heim R, Singh A, Olson ER, Greenberg EP.

Antimicrob Agents Chemother. 2006 Nov;50(11):3674-9. Epub 2006 Sep 11.


In vitro characterization of the antibacterial spectrum of novel bacterial type II topoisomerase inhibitors of the aminobenzimidazole class.

Mani N, Gross CH, Parsons JD, Hanzelka B, Müh U, Mullin S, Liao Y, Grillot AL, Stamos D, Charifson PS, Grossman TH.

Antimicrob Agents Chemother. 2006 Apr;50(4):1228-37.


Class I and III polyhydroxyalkanoate synthases from Ralstonia eutropha and Allochromatium vinosum: characterization and substrate specificity studies.

Yuan W, Jia Y, Tian J, Snell KD, Müh U, Sinskey AJ, Lambalot RH, Walsh CT, Stubbe J.

Arch Biochem Biophys. 2001 Oct 1;394(1):87-98.


PHA synthase from chromatium vinosum: cysteine 149 is involved in covalent catalysis.

Müh U, Sinskey AJ, Kirby DP, Lane WS, Stubbe J.

Biochemistry. 1999 Jan 12;38(2):826-37.


Lactate monooxygenase. II. Site-directed mutagenesis of the postulated active site base histidine 290.

Müh U, Williams CH Jr, Massey V.

J Biol Chem. 1994 Mar 18;269(11):7989-93.


Direct effect of protirelin (TRH) on PB[123I] in autonomous thyroid adenoma.

Kallee E, Müh U, Wahl R.

Thyroidology. 1993 Dec;5(3):81-5.


The pyramidal lobe--a helpful criterion in the differential diagnosis of thyroid diseases.

Wahl R, Müh U, Kallee E.

Klin Wochenschr. 1989 Jun 15;67(12):647. No abstract available.


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