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Items: 49

1.

Nanobody stability engineering by employing the ΔTm shift; a comparison with apparent rate constants of heat-induced aggregation.

Kunz P, Ortale A, Mücke N, Zinner K, Hoheisel JD.

Protein Eng Des Sel. 2019 Dec 31;32(5):241-249. doi: 10.1093/protein/gzz017.

PMID:
31340035
2.

The structural basis of nanobody unfolding reversibility and thermoresistance.

Kunz P, Zinner K, Mücke N, Bartoschik T, Muyldermans S, Hoheisel JD.

Sci Rep. 2018 May 21;8(1):7934. doi: 10.1038/s41598-018-26338-z.

3.

Assembly Kinetics of Vimentin Tetramers to Unit-Length Filaments: A Stopped-Flow Study.

Mücke N, Kämmerer L, Winheim S, Kirmse R, Krieger J, Mildenberger M, Baßler J, Hurt E, Goldmann WH, Aebi U, Toth K, Langowski J, Herrmann H.

Biophys J. 2018 May 22;114(10):2408-2418. doi: 10.1016/j.bpj.2018.04.032. Epub 2018 May 10.

4.

Threonine 150 Phosphorylation of Keratin 5 Is Linked to Epidermolysis Bullosa Simplex and Regulates Filament Assembly and Cell Viability.

Sawant M, Schwarz N, Windoffer R, Magin TM, Krieger J, Mücke N, Obara B, Jankowski V, Jankowski J, Wally V, Lettner T, Leube RE.

J Invest Dermatol. 2018 Mar;138(3):627-636. doi: 10.1016/j.jid.2017.10.011. Epub 2017 Dec 6.

5.

Effects of charge-modifying mutations in histone H2A α3-domain on nucleosome stability assessed by single-pair FRET and MD simulations.

Lehmann K, Zhang R, Schwarz N, Gansen A, Mücke N, Langowski J, Toth K.

Sci Rep. 2017 Oct 16;7(1):13303. doi: 10.1038/s41598-017-13416-x.

6.

Defining the epichromatin epitope.

Gould TJ, Tóth K, Mücke N, Langowski J, Hakusui AS, Olins AL, Olins DE.

Nucleus. 2017 Nov 2;8(6):625-640. doi: 10.1080/19491034.2017.1380141. Epub 2017 Oct 30.

7.

Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq.

Schulz EC, Seiler M, Zuliani C, Voigt F, Rybin V, Pogenberg V, Mücke N, Wilmanns M, Gibson TJ, Barabas O.

Sci Rep. 2017 Aug 29;7(1):9903. doi: 10.1038/s41598-017-10085-8.

8.

Insights into the molecular architecture and histone H3-H4 deposition mechanism of yeast Chromatin assembly factor 1.

Sauer PV, Timm J, Liu D, Sitbon D, Boeri-Erba E, Velours C, Mücke N, Langowski J, Ochsenbein F, Almouzni G, Panne D.

Elife. 2017 Mar 18;6. pii: e23474. doi: 10.7554/eLife.23474.

9.

Structural Dynamics of the Vimentin Coiled-coil Contact Regions Involved in Filament Assembly as Revealed by Hydrogen-Deuterium Exchange.

Premchandar A, Mücke N, Poznański J, Wedig T, Kaus-Drobek M, Herrmann H, Dadlez M.

J Biol Chem. 2016 Nov 25;291(48):24931-24950. Epub 2016 Sep 30.

10.

EGFP oligomers as natural fluorescence and hydrodynamic standards.

Vámosi G, Mücke N, Müller G, Krieger JW, Curth U, Langowski J, Tóth K.

Sci Rep. 2016 Sep 13;6:33022. doi: 10.1038/srep33022.

11.

In Vitro Assembly Kinetics of Cytoplasmic Intermediate Filaments: A Correlative Monte Carlo Simulation Study.

Mücke N, Winheim S, Merlitz H, Buchholz J, Langowski J, Herrmann H.

PLoS One. 2016 Jun 15;11(6):e0157451. doi: 10.1371/journal.pone.0157451. eCollection 2016.

12.

Analysis of distinct molecular assembly complexes of keratin K8 and K18 by hydrogen-deuterium exchange.

Premchandar A, Kupniewska A, Tarnowski K, Mücke N, Mauermann M, Kaus-Drobek M, Edelman A, Herrmann H, Dadlez M.

J Struct Biol. 2015 Dec;192(3):426-440. doi: 10.1016/j.jsb.2015.10.001. Epub 2015 Oct 3.

PMID:
26434626
13.

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation.

Zhao H, Ghirlando R, Alfonso C, Arisaka F, Attali I, Bain DL, Bakhtina MM, Becker DF, Bedwell GJ, Bekdemir A, Besong TM, Birck C, Brautigam CA, Brennerman W, Byron O, Bzowska A, Chaires JB, Chaton CT, Cölfen H, Connaghan KD, Crowley KA, Curth U, Daviter T, Dean WL, Díez AI, Ebel C, Eckert DM, Eisele LE, Eisenstein E, England P, Escalante C, Fagan JA, Fairman R, Finn RM, Fischle W, de la Torre JG, Gor J, Gustafsson H, Hall D, Harding SE, Cifre JG, Herr AB, Howell EE, Isaac RS, Jao SC, Jose D, Kim SJ, Kokona B, Kornblatt JA, Kosek D, Krayukhina E, Krzizike D, Kusznir EA, Kwon H, Larson A, Laue TM, Le Roy A, Leech AP, Lilie H, Luger K, Luque-Ortega JR, Ma J, May CA, Maynard EL, Modrak-Wojcik A, Mok YF, Mücke N, Nagel-Steger L, Narlikar GJ, Noda M, Nourse A, Obsil T, Park CK, Park JK, Pawelek PD, Perdue EE, Perkins SJ, Perugini MA, Peterson CL, Peverelli MG, Piszczek G, Prag G, Prevelige PE, Raynal BD, Rezabkova L, Richter K, Ringel AE, Rosenberg R, Rowe AJ, Rufer AC, Scott DJ, Seravalli JG, Solovyova AS, Song R, Staunton D, Stoddard C, Stott K, Strauss HM, Streicher WW, Sumida JP, Swygert SG, Szczepanowski RH, Tessmer I, Toth RT 4th, Tripathy A, Uchiyama S, Uebel SF, Unzai S, Gruber AV, von Hippel PH, Wandrey C, Wang SH, Weitzel SE, Wielgus-Kutrowska B, Wolberger C, Wolff M, Wright E, Wu YS, Wubben JM, Schuck P.

PLoS One. 2015 May 21;10(5):e0126420. doi: 10.1371/journal.pone.0126420. eCollection 2015.

14.

Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold.

Gaik M, Flemming D, von Appen A, Kastritis P, Mücke N, Fischer J, Stelter P, Ori A, Bui KH, Baßler J, Barbar E, Beck M, Hurt E.

J Cell Biol. 2015 Feb 2;208(3):283-97. doi: 10.1083/jcb.201411003.

15.

Attractive interactions among intermediate filaments determine network mechanics in vitro.

Pawelzyk P, Mücke N, Herrmann H, Willenbacher N.

PLoS One. 2014 Apr 1;9(4):e93194. doi: 10.1371/journal.pone.0093194. eCollection 2014. Erratum in: PLoS One. 2014;9(9): doi/10.1371/journal.pone.0109450.

16.

Reconstitution of the human cytoplasmic dynein complex.

Trokter M, Mücke N, Surrey T.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20895-900. doi: 10.1073/pnas.1210573110. Epub 2012 Dec 4.

17.

Complex formation and kinetics of filament assembly exhibited by the simple epithelial keratins K8 and K18.

Lichtenstern T, Mücke N, Aebi U, Mauermann M, Herrmann H.

J Struct Biol. 2012 Jan;177(1):54-62. doi: 10.1016/j.jsb.2011.11.003. Epub 2011 Nov 9.

PMID:
22085677
18.

Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I).

Binder M, Eberle F, Seitz S, Mücke N, Hüber CM, Kiani N, Kaderali L, Lohmann V, Dalpke A, Bartenschlager R.

J Biol Chem. 2011 Aug 5;286(31):27278-87. doi: 10.1074/jbc.M111.256974. Epub 2011 Jun 9.

19.

Deconstructing the late phase of vimentin assembly by total internal reflection fluorescence microscopy (TIRFM).

Winheim S, Hieb AR, Silbermann M, Surmann EM, Wedig T, Herrmann H, Langowski J, Mücke N.

PLoS One. 2011 Apr 22;6(4):e19202. doi: 10.1371/journal.pone.0019202.

20.

Distinct binding properties distinguish LQ-type calmodulin-binding domains in cyclic nucleotide-gated channels.

Ungerer N, Mücke N, Broecker J, Keller S, Frings S, Möhrlen F.

Biochemistry. 2011 Apr 19;50(15):3221-8. doi: 10.1021/bi200115m. Epub 2011 Mar 25.

PMID:
21413724
21.

Mutations in desmin's carboxy-terminal "tail" domain severely modify filament and network mechanics.

Bär H, Schopferer M, Sharma S, Hochstein B, Mücke N, Herrmann H, Willenbacher N.

J Mol Biol. 2010 Apr 16;397(5):1188-98. doi: 10.1016/j.jmb.2010.02.024. Epub 2010 Feb 18.

PMID:
20171226
22.

Vimentin intermediate filament formation: in vitro measurement and mathematical modeling of the filament length distribution during assembly.

Portet S, Mücke N, Kirmse R, Langowski J, Beil M, Herrmann H.

Langmuir. 2009 Aug 4;25(15):8817-23.

PMID:
20050052
23.

Characterization of the head-to-tail overlap complexes formed by human lamin A, B1 and B2 "half-minilamin" dimers.

Kapinos LE, Schumacher J, Mücke N, Machaidze G, Burkhard P, Aebi U, Strelkov SV, Herrmann H.

J Mol Biol. 2010 Feb 26;396(3):719-31. doi: 10.1016/j.jmb.2009.12.001. Epub 2009 Dec 7.

PMID:
20004208
24.

Filamentous biopolymers on surfaces: atomic force microscopy images compared with Brownian dynamics simulation of filament deposition.

Mücke N, Klenin K, Kirmse R, Bussiek M, Herrmann H, Hafner M, Langowski J.

PLoS One. 2009 Nov 4;4(11):e7756. doi: 10.1371/journal.pone.0007756.

25.

Disease mutations in the "head" domain of the extra-sarcomeric protein desmin distinctly alter its assembly and network-forming properties.

Sharma S, Mücke N, Katus HA, Herrmann H, Bär H.

J Mol Med (Berl). 2009 Dec;87(12):1207-19. doi: 10.1007/s00109-009-0521-9. Epub 2009 Sep 8.

PMID:
19763525
26.

Interference of amino-terminal desmin fragments with desmin filament formation.

Bär H, Sharma S, Kleiner H, Mücke N, Zentgraf H, Katus HA, Aebi U, Herrmann H.

Cell Motil Cytoskeleton. 2009 Nov;66(11):986-99. doi: 10.1002/cm.20396.

PMID:
19530175
27.

Analysis of modified human papillomavirus type 16 L1 capsomeres: the ability to assemble into larger particles correlates with higher immunogenicity.

Schädlich L, Senger T, Gerlach B, Mücke N, Klein C, Bravo IG, Müller M, Gissmann L.

J Virol. 2009 Aug;83(15):7690-705. doi: 10.1128/JVI.02588-08. Epub 2009 May 20.

28.

Desmin and vimentin intermediate filament networks: their viscoelastic properties investigated by mechanical rheometry.

Schopferer M, Bär H, Hochstein B, Sharma S, Mücke N, Herrmann H, Willenbacher N.

J Mol Biol. 2009 Apr 24;388(1):133-43. doi: 10.1016/j.jmb.2009.03.005. Epub 2009 Mar 10.

PMID:
19281820
29.

A quantitative kinetic model for the in vitro assembly of intermediate filaments from tetrameric vimentin.

Kirmse R, Portet S, Mücke N, Aebi U, Herrmann H, Langowski J.

J Biol Chem. 2007 Jun 22;282(25):18563-72. Epub 2007 Apr 2.

30.

Conspicuous involvement of desmin tail mutations in diverse cardiac and skeletal myopathies.

Bär H, Goudeau B, Wälde S, Casteras-Simon M, Mücke N, Shatunov A, Goldberg YP, Clarke C, Holton JL, Eymard B, Katus HA, Fardeau M, Goldfarb L, Vicart P, Herrmann H.

Hum Mutat. 2007 Apr;28(4):374-86.

PMID:
17221859
31.

Assembly defects of desmin disease mutants carrying deletions in the alpha-helical rod domain are rescued by wild type protein.

Bär H, Mücke N, Katus HA, Aebi U, Herrmann H.

J Struct Biol. 2007 Apr;158(1):107-15. Epub 2006 Nov 10.

PMID:
17188893
32.

Monitoring intermediate filament assembly by small-angle x-ray scattering reveals the molecular architecture of assembly intermediates.

Sokolova AV, Kreplak L, Wedig T, Mücke N, Svergun DI, Herrmann H, Aebi U, Strelkov SV.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16206-11. Epub 2006 Oct 18.

33.

Interactions between merozoite surface proteins 1, 6, and 7 of the malaria parasite Plasmodium falciparum.

Kauth CW, Woehlbier U, Kern M, Mekonnen Z, Lutz R, Mücke N, Langowski J, Bujard H.

J Biol Chem. 2006 Oct 20;281(42):31517-27. Epub 2006 Aug 29.

34.

Impact of disease mutations on the desmin filament assembly process.

Bär H, Mücke N, Ringler P, Müller SA, Kreplak L, Katus HA, Aebi U, Herrmann H.

J Mol Biol. 2006 Jul 28;360(5):1031-42. Epub 2006 Jun 16.

PMID:
16828798
35.

Solubility properties and specific assembly pathways of the B-type lamin from Caenorhabditis elegans.

Foeger N, Wiesel N, Lotsch D, Mücke N, Kreplak L, Aebi U, Gruenbaum Y, Herrmann H.

J Struct Biol. 2006 Aug;155(2):340-50. Epub 2006 Apr 27.

PMID:
16713298
36.

Mutations in vimentin disrupt the cytoskeleton in fibroblasts and delay execution of apoptosis.

Schietke R, Bröhl D, Wedig T, Mücke N, Herrmann H, Magin TM.

Eur J Cell Biol. 2006 Jan;85(1):1-10. Epub 2005 Nov 8.

PMID:
16373170
37.

Severe muscle disease-causing desmin mutations interfere with in vitro filament assembly at distinct stages.

Bär H, Mücke N, Kostareva A, Sjöberg G, Aebi U, Herrmann H.

Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15099-104. Epub 2005 Oct 10.

38.

Investigation of the morphology of intermediate filaments adsorbed to different solid supports.

Mücke N, Kirmse R, Wedig T, Leterrier JF, Kreplak L.

J Struct Biol. 2005 Jun;150(3):268-76. Epub 2005 Apr 2.

PMID:
15890275
39.

Characterization of the in vitro co-assembly process of the intermediate filament proteins vimentin and desmin: mixed polymers at all stages of assembly.

Wickert U, Mücke N, Wedig T, Müller SA, Aebi U, Herrmann H.

Eur J Cell Biol. 2005 Mar;84(2-3):379-91.

PMID:
15819415
40.

Molecular and biophysical characterization of assembly-starter units of human vimentin.

Mücke N, Wedig T, Bürer A, Marekov LN, Steinert PM, Langowski J, Aebi U, Herrmann H.

J Mol Biol. 2004 Jun 25;340(1):97-114.

PMID:
15184025
41.

Assessing the flexibility of intermediate filaments by atomic force microscopy.

Mücke N, Kreplak L, Kirmse R, Wedig T, Herrmann H, Aebi U, Langowski J.

J Mol Biol. 2004 Jan 30;335(5):1241-50.

PMID:
14729340
42.

Conformation of reconstituted mononucleosomes and effect of linker histone H1 binding studied by scanning force microscopy.

Kepert JF, Tóth KF, Caudron M, Mücke N, Langowski J, Rippe K.

Biophys J. 2003 Dec;85(6):4012-22.

44.

The in vitro assembly of hair follicle keratins: comparison of cortex and companion layer keratins.

Hofmann I, Winter H, Mücke N, Langowski J, Schweizer J.

Biol Chem. 2002 Sep;383(9):1373-81.

PMID:
12437130
45.
46.

Physical characterization of plakophilin 1 reconstituted with and without zinc.

Hofmann I, Mücke N, Reed J, Herrmann H, Langowski J.

Eur J Biochem. 2000 Jul;267(14):4381-9.

47.

Scanning force microscopy of Escherichia coli RNA polymerase.sigma54 holoenzyme complexes with DNA in buffer and in air.

Schulz A, Mücke N, Langowski J, Rippe K.

J Mol Biol. 1998 Nov 6;283(4):821-36.

PMID:
9790843
48.
49.

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