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Items: 1 to 50 of 154

1.

A call for action: Improve reporting of research studies to increase the scientific basis for regulatory decision-making.

Ågerstrand M, Christiansen S, Hanberg A, Rudén C, Andersson L, Andersen S, Appelgren H, Bjørge C, Clausen IH, Eide DM, Hartmann NB, Husøy T, Halldórsson HP, van der Hagen M, Ingre-Khans E, Lillicrap AD, Beltoft VM, Mörk AK, Murtomaa-Hautala M, Nielsen E, Ólafsdóttir K, Palomäki J, Papponen H, Reiler EM, Stockmann-Juvala H, Suutari T, Tyle H, Beronius A.

J Appl Toxicol. 2018 May;38(5):783-785. doi: 10.1002/jat.3578. Epub 2018 Jan 3.

2.

A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission.

Nielsen J, Fejgin K, Sotty F, Nielsen V, Mørk A, Christoffersen CT, Yavich L, Lauridsen JB, Clausen D, Larsen PH, Egebjerg J, Werge TM, Kallunki P, Christensen KV, Didriksen M.

Transl Psychiatry. 2017 Nov 30;7(11):1261. doi: 10.1038/s41398-017-0011-8.

3.

Acute effects of vortioxetine and duloxetine on resting-state functional connectivity in the awake rat.

Pérez PD, Ma Z, Hamilton C, Sánchez C, Mørk A, Pehrson AL, Bundgaard C, Zhang N.

Neuropharmacology. 2018 Jan;128:379-387. doi: 10.1016/j.neuropharm.2017.10.038. Epub 2017 Nov 2.

PMID:
29104073
4.

Sequential Vacc-4x and romidepsin during combination antiretroviral therapy (cART): Immune responses to Vacc-4x regions on p24 and changes in HIV reservoirs.

Tapia G, Højen JF, Ökvist M, Olesen R, Leth S, Nissen SK, VanBelzen DJ, O'Doherty U, Mørk A, Krogsgaard K, Søgaard OS, Østergaard L, Tolstrup M, Pantaleo G, Sommerfelt MA.

J Infect. 2017 Dec;75(6):555-571. doi: 10.1016/j.jinf.2017.09.004. Epub 2017 Sep 14.

PMID:
28917661
5.
6.

The Care Team Visit: Approaching Interdisciplinary Rounds With Renewed Focus.

Malec A, Mørk A, Hoffman R, Carlson E.

J Nurs Care Qual. 2018 Apr/Jun;33(2):135-142. doi: 10.1097/NCQ.0000000000000279.

PMID:
28767466
7.

Including surface ligand effects in continuum elastic models of nanocrystal vibrations.

Lee EMY, Mork AJ, Willard AP, Tisdale WA.

J Chem Phys. 2017 Jul 28;147(4):044711. doi: 10.1063/1.4995439.

PMID:
28764341
8.

Antagonism of the 5-HT6 receptor - Preclinical rationale for the treatment of Alzheimer's disease.

de Jong IEM, Mørk A.

Neuropharmacology. 2017 Oct;125:50-63. doi: 10.1016/j.neuropharm.2017.07.010. Epub 2017 Jul 12. Review.

PMID:
28711518
9.

Using Kotter's Change Framework to Implement and Sustain Multiple Complementary ICU Initiatives.

Mørk A, Krupp A, Hankwitz J, Malec A.

J Nurs Care Qual. 2018 Jan/Mar;33(1):38-45. doi: 10.1097/NCQ.0000000000000263.

PMID:
28658182
10.

Effects of the 5-HT6 receptor antagonist idalopirdine on extracellular levels of monoamines, glutamate and acetylcholine in the rat medial prefrontal cortex.

Mørk A, Russell RV, de Jong IE, Smagin G.

Eur J Pharmacol. 2017 Mar 15;799:1-6. doi: 10.1016/j.ejphar.2017.02.010. Epub 2017 Feb 8.

PMID:
28188762
11.

Involvement of presynaptic 5-HT1A receptors in the low propensity of brexpiprazole to induce extrapyramidal side effects in rats.

Mombereau C, Arnt J, Mørk A.

Pharmacol Biochem Behav. 2017 Feb;153:141-146. doi: 10.1016/j.pbb.2016.12.015. Epub 2017 Jan 3.

PMID:
28057524
12.

Selegiline induces a wake promoting effect in rats which is related to formation of its active metabolites.

Bundgaard C, Montezinho LP, Anderson N, Thomsen C, Mørk A.

Pharmacol Biochem Behav. 2016 Nov - Dec;150-151:147-152. doi: 10.1016/j.pbb.2016.10.003. Epub 2016 Oct 29.

PMID:
27984094
13.

The Schizophrenia-Associated BRD1 Gene Regulates Behavior, Neurotransmission, and Expression of Schizophrenia Risk Enriched Gene Sets in Mice.

Qvist P, Christensen JH, Vardya I, Rajkumar AP, Mørk A, Paternoster V, Füchtbauer EM, Pallesen J, Fryland T, Dyrvig M, Hauberg ME, Lundsberg B, Fejgin K, Nyegaard M, Jensen K, Nyengaard JR, Mors O, Didriksen M, Børglum AD.

Biol Psychiatry. 2017 Jul 1;82(1):62-76. doi: 10.1016/j.biopsych.2016.08.037. Epub 2016 Sep 15.

PMID:
27837920
14.
15.

Modulation of Low-Frequency Acoustic Vibrations in Semiconductor Nanocrystals through Choice of Surface Ligand.

Mork AJ, Lee EMY, Dahod NS, Willard AP, Tisdale WA.

J Phys Chem Lett. 2016 Oct 20;7(20):4213-4216. doi: 10.1021/acs.jpclett.6b01659. Epub 2016 Oct 10.

PMID:
27700102
16.

Combined effect of Vacc-4x, recombinant human granulocyte macrophage colony-stimulating factor vaccination, and romidepsin on the HIV-1 reservoir (REDUC): a single-arm, phase 1B/2A trial.

Leth S, Schleimann MH, Nissen SK, Højen JF, Olesen R, Graversen ME, Jørgensen S, Kjær AS, Denton PW, Mørk A, Sommerfelt MA, Krogsgaard K, Østergaard L, Rasmussen TA, Tolstrup M, Søgaard OS.

Lancet HIV. 2016 Oct;3(10):e463-72. doi: 10.1016/S2352-3018(16)30055-8. Epub 2016 Jul 7.

PMID:
27658863
17.

Task- and Treatment Length-Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats.

Pehrson AL, Hillhouse TM, Haddjeri N, Rovera R, Porter JH, Mørk A, Smagin G, Song D, Budac D, Cajina M, Sanchez C.

J Pharmacol Exp Ther. 2016 Sep;358(3):472-82. doi: 10.1124/jpet.116.233924. Epub 2016 Jul 11.

18.

Evidence for Compensatory Photosynthetic and Yield Response of Soybeans to Aphid Herbivory.

Kucharik CJ, Mork AC, Meehan TD, Serbin SP, Singh A, Townsend PA, Stack Whitney K, Gratton C.

J Econ Entomol. 2016 Apr 13;109(3):1177-1187. doi: 10.1093/jee/tow066.

PMID:
27076674
19.

The 5-HT6 receptor antagonist idalopirdine potentiates the effects of acetylcholinesterase inhibition on neuronal network oscillations and extracellular acetylcholine levels in the rat dorsal hippocampus.

Herrik KF, Mørk A, Richard N, Bundgaard C, Bastlund JF, de Jong IEM.

Neuropharmacology. 2016 Aug;107:351-363. doi: 10.1016/j.neuropharm.2016.03.043. Epub 2016 Mar 31.

20.

Pharmacokinetic/Pharmacodynamic Relationship of Gabapentin in a CFA-induced Inflammatory Hyperalgesia Rat Model.

Larsen MS, Keizer R, Munro G, Mørk A, Holm R, Savic R, Kreilgaard M.

Pharm Res. 2016 May;33(5):1133-43. doi: 10.1007/s11095-016-1859-7. Epub 2016 Jan 15.

PMID:
26780452
21.

Comparing Pharmacological Modulation of Sensory Gating in Healthy Humans and Rats: The Effects of Reboxetine and Haloperidol.

Witten L, Bastlund JF, Glenthøj BY, Bundgaard C, Steiniger-Brach B, Mørk A, Oranje B.

Neuropsychopharmacology. 2016 Jan;41(2):638-45. doi: 10.1038/npp.2015.194. Epub 2015 Jul 1.

22.

A 5-HT3 receptor antagonist potentiates the behavioral, neurochemical and electrophysiological actions of an SSRI antidepressant.

Bétry C, Overstreet D, Haddjeri N, Pehrson AL, Bundgaard C, Sanchez C, Mørk A.

Pharmacol Biochem Behav. 2015 Apr;131:136-42. doi: 10.1016/j.pbb.2015.02.011. Epub 2015 Feb 16.

PMID:
25697477
23.

Precision-cut intestinal slices as a culture system to analyze the infection of differentiated intestinal epithelial cells by avian influenza viruses.

Punyadarsaniya D, Winter C, Mork AK, Amiri M, Naim HY, Rautenschlein S, Herrler G.

J Virol Methods. 2015 Feb;212:71-5. doi: 10.1016/j.jviromet.2014.10.015. Epub 2014 Nov 13.

PMID:
25445801
24.

Physiologically based pharmacokinetic modeling of hydrogen cyanide levels in human breath.

Stamyr K, Mörk AK, Johanson G.

Arch Toxicol. 2015 Aug;89(8):1287-96. doi: 10.1007/s00204-014-1310-y. Epub 2014 Jul 29.

PMID:
25069802
25.

Hippocampal P3-like auditory event-related potentials are disrupted in a rat model of cholinergic degeneration in Alzheimer's disease: reversal by donepezil treatment.

Laursen B, Mørk A, Kristiansen U, Bastlund JF.

J Alzheimers Dis. 2014;42(4):1179-89. doi: 10.3233/JAD-131502.

PMID:
25024305
26.

Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulator.

Maeda K, Sugino H, Akazawa H, Amada N, Shimada J, Futamura T, Yamashita H, Ito N, McQuade RD, Mørk A, Pehrson AL, Hentzer M, Nielsen V, Bundgaard C, Arnt J, Stensbøl TB, Kikuchi T.

J Pharmacol Exp Ther. 2014 Sep;350(3):589-604. doi: 10.1124/jpet.114.213793. Epub 2014 Jun 19.

PMID:
24947465
27.
28.

Subdiffusive exciton transport in quantum dot solids.

Akselrod GM, Prins F, Poulikakos LV, Lee EM, Weidman MC, Mork AJ, Willard AP, Bulović V, Tisdale WA.

Nano Lett. 2014 Jun 11;14(6):3556-62. doi: 10.1021/nl501190s. Epub 2014 May 13.

PMID:
24807586
29.

Does stress elicit depression? Evidence from clinical and preclinical studies.

Sickmann HM, Li Y, Mørk A, Sanchez C, Gulinello M.

Curr Top Behav Neurosci. 2014;18:123-59. doi: 10.1007/7854_2014_292.

PMID:
24633891
30.

Adjustment factors for toluene, styrene and methyl chloride by population modeling of toxicokinetic variability.

Mörk AK, Jonsson F, Johanson G.

Regul Toxicol Pharmacol. 2014 Jun;69(1):78-90. doi: 10.1016/j.yrtph.2014.02.015. Epub 2014 Mar 6.

PMID:
24613484
31.

Auditory sensory processing deficits in sensory gating and mismatch negativity-like responses in the social isolation rat model of schizophrenia.

Witten L, Oranje B, Mørk A, Steiniger-Brach B, Glenthøj BY, Bastlund JF.

Behav Brain Res. 2014 Jun 1;266:85-93. doi: 10.1016/j.bbr.2014.02.048. Epub 2014 Mar 5.

PMID:
24613239
32.

Addiction-related effects of DOV 216,303 and cocaine: A comparative study in the mouse.

Sørensen G, Husum H, Brennum LT, Bundgaard C, Montezinho LC, Mørk A, Wörtwein G, Woldbye DP.

Basic Clin Pharmacol Toxicol. 2014 Jun;114(6):451-9. doi: 10.1111/bcpt.12182. Epub 2014 Jan 16.

33.

Impaired hippocampal acetylcholine release parallels spatial memory deficits in Tg2576 mice subjected to basal forebrain cholinergic degeneration.

Laursen B, Mørk A, Plath N, Kristiansen U, Bastlund JF.

Brain Res. 2014 Jan 16;1543:253-62. doi: 10.1016/j.brainres.2013.10.055. Epub 2013 Nov 11.

PMID:
24231553
34.
35.

Cost-effectiveness of roflumilast as an add-on treatment to long-acting bronchodilators in the treatment of COPD associated with chronic bronchitis in the United Kingdom.

Samyshkin Y, Kotchie RW, Mörk AC, Briggs AH, Bateman ED.

Eur J Health Econ. 2014 Jan;15(1):69-82. doi: 10.1007/s10198-013-0456-5. Epub 2013 Feb 8.

36.

Vortioxetine (Lu AA21004), a novel multimodal antidepressant, enhances memory in rats.

Mørk A, Montezinho LP, Miller S, Trippodi-Murphy C, Plath N, Li Y, Gulinello M, Sanchez C.

Pharmacol Biochem Behav. 2013 Apr;105:41-50. doi: 10.1016/j.pbb.2013.01.019. Epub 2013 Feb 1.

37.

Cholinergic degeneration is associated with increased plaque deposition and cognitive impairment in APPswe/PS1dE9 mice.

Laursen B, Mørk A, Plath N, Kristiansen U, Bastlund JF.

Behav Brain Res. 2013 Mar 1;240:146-52. doi: 10.1016/j.bbr.2012.11.012. Epub 2012 Nov 22.

PMID:
23178660
38.

Therapeutic potential of metabotropic glutamate receptor modulators.

Hovelsø N, Sotty F, Montezinho LP, Pinheiro PS, Herrik KF, Mørk A.

Curr Neuropharmacol. 2012 Mar;10(1):12-48. doi: 10.2174/157015912799362805.

39.

An air-stable low-bandgap n-type organic polymer semiconductor exhibiting selective solubility in perfluorinated solvents.

Takeda Y, Andrew TL, Lobez JM, Mork AJ, Swager TM.

Angew Chem Int Ed Engl. 2012 Sep 3;51(36):9042-6. doi: 10.1002/anie.201204066. Epub 2012 Aug 9.

PMID:
22887312
40.

Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder.

Mørk A, Pehrson A, Brennum LT, Nielsen SM, Zhong H, Lassen AB, Miller S, Westrich L, Boyle NJ, Sánchez C, Fischer CW, Liebenberg N, Wegener G, Bundgaard C, Hogg S, Bang-Andersen B, Stensbøl TB.

J Pharmacol Exp Ther. 2012 Mar;340(3):666-75. doi: 10.1124/jpet.111.189068. Epub 2011 Dec 9.

PMID:
22171087
41.

Involvement of a subpopulation of neuronal M4 muscarinic acetylcholine receptors in the antipsychotic-like effects of the M1/M4 preferring muscarinic receptor agonist xanomeline.

Dencker D, Wörtwein G, Weikop P, Jeon J, Thomsen M, Sager TN, Mørk A, Woldbye DP, Wess J, Fink-Jensen A.

J Neurosci. 2011 Apr 20;31(16):5905-8. doi: 10.1523/JNEUROSCI.0370-11.2011.

42.

Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder.

Bang-Andersen B, Ruhland T, Jørgensen M, Smith G, Frederiksen K, Jensen KG, Zhong H, Nielsen SM, Hogg S, Mørk A, Stensbøl TB.

J Med Chem. 2011 May 12;54(9):3206-21. doi: 10.1021/jm101459g. Epub 2011 Apr 12.

PMID:
21486038
44.

The effects of acute treatment with escitalopram on the different stages of contextual fear conditioning are reversed by atomoxetine.

Montezinho LP, Miller S, Plath N, Jensen NH, Karlsson JJ, Witten L, Mørk A.

Psychopharmacology (Berl). 2010 Oct;212(2):131-43. doi: 10.1007/s00213-010-1917-5. Epub 2010 Jul 30.

PMID:
20676614
45.

HIF prolyl hydroxylase inhibition increases cell viability and potentiates dopamine release in dopaminergic cells.

Johansen JL, Sager TN, Lotharius J, Witten L, Mørk A, Egebjerg J, Thirstrup K.

J Neurochem. 2010 Oct;115(1):209-19. doi: 10.1111/j.1471-4159.2010.06917.x. Epub 2010 Aug 19.

46.

Percutaneous laser disc decompression for thoracic disc disease: report of 10 cases.

Haufe SM, Mork AR, Pyne M, Baker RA.

Int J Med Sci. 2010 Jun 1;7(3):155-9.

47.
48.

Chemical-specific adjustment factors for intraspecies variability of acetone toxicokinetics using a probabilistic approach.

Mörk AK, Johanson G.

Toxicol Sci. 2010 Jul;116(1):336-48. doi: 10.1093/toxsci/kfq116. Epub 2010 Apr 16.

PMID:
20400482
49.

A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors.

Jeon J, Dencker D, Wörtwein G, Woldbye DP, Cui Y, Davis AA, Levey AI, Schütz G, Sager TN, Mørk A, Li C, Deng CX, Fink-Jensen A, Wess J.

J Neurosci. 2010 Feb 10;30(6):2396-405. doi: 10.1523/JNEUROSCI.3843-09.2010.

50.

Nest building performance following MPTP toxicity in mice.

Sager TN, Kirchhoff J, Mørk A, Van Beek J, Thirstrup K, Didriksen M, Lauridsen JB.

Behav Brain Res. 2010 Apr 2;208(2):444-9. doi: 10.1016/j.bbr.2009.12.014. Epub 2009 Dec 23.

PMID:
20035793

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