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Items: 28

1.

Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP Inhibitors In Vitro and In Vivo.

Siemeister G, Mengel A, Fernández-Montalván AE, Bone W, Schröder J, Zitzmann-Kolbe S, Briem H, Prechtl S, Holton SJ, Mönning U, von Ahsen O, Johanssen S, Cleve A, Pütter V, Hitchcock M, von Nussbaum F, Brands M, Ziegelbauer K, Mumberg D.

Clin Cancer Res. 2019 Feb 15;25(4):1404-1414. doi: 10.1158/1078-0432.CCR-18-0628. Epub 2018 Nov 14.

PMID:
30429199
2.

Super-enhancers define a proliferative PGC-1α-expressing melanoma subgroup sensitive to BET inhibition.

Gelato KA, Schöckel L, Klingbeil O, Rückert T, Lesche R, Toedling J, Kalfon E, Héroult M, Lejeune P, Mönning U, Fernández-Montalván AE, Bäurle S, Siegel S, Haendler B.

Oncogene. 2018 Jan 25;37(4):512-521. doi: 10.1038/onc.2017.325. Epub 2017 Oct 9.

3.

Preclinical evaluation of BAY 1075553, a novel (18)F-labelled inhibitor of prostate-specific membrane antigen for PET imaging of prostate cancer.

Lesche R, Kettschau G, Gromov AV, Böhnke N, Borkowski S, Mönning U, Hegele-Hartung C, Döhr O, Dinkelborg LM, Graham K.

Eur J Nucl Med Mol Imaging. 2014 Jan;41(1):89-101. doi: 10.1007/s00259-013-2527-3. Epub 2013 Aug 17.

PMID:
23955632
4.

Gene expression profiling of scrapie-infected brain tissue.

Riemer C, Neidhold S, Burwinkel M, Schwarz A, Schultz J, Krätzschmar J, Mönning U, Baier M.

Biochem Biophys Res Commun. 2004 Oct 15;323(2):556-64.

PMID:
15369787
5.

Cerebrospinal fluid levels of amyloid precursor protein and amyloid beta-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity.

Hock C, Golombowski S, Müller-Spahn F, Naser W, Beyreuther K, Mönning U, Schenk D, Vigo-Pelfrey C, Bush AM, Moir R, Tanzi RE, Growdon JH, Nitsch RM.

Eur Neurol. 1998;39(2):111-8.

PMID:
9520072
6.

Expression of the APP gene family in brain cells, brain development and aging.

Sandbrink R, Mönning U, Masters CL, Beyreuther K.

Gerontology. 1997;43(1-2):119-31.

PMID:
8996834
7.

Regulation of APP expression, biogenesis and metabolism by extracellular matrix and cytokines.

Beyreuther K, Multhaup G, Mönning U, Sandbrink R, Beher D, Hesse L, Small DH, Masters CL.

Ann N Y Acad Sci. 1996 Jan 17;777:74-6. Review.

PMID:
8624129
8.

The amplifying effect of beta-amyloid on cellular calcium signalling is reduced in Alzheimer's disease.

Eckert A, Förstl H, Hartmann H, Czech C, Mönning U, Beyreuther K, Müller WE.

Neuroreport. 1995 May 30;6(8):1199-202.

PMID:
7662907
9.

Intracellular routing of human amyloid protein precursor: axonal delivery followed by transport to the dendrites.

Simons M, Ikonen E, Tienari PJ, Cid-Arregui A, Mönning U, Beyreuther K, Dotti CG.

J Neurosci Res. 1995 May 1;41(1):121-8.

PMID:
7674373
10.

Extracellular matrix influences the biogenesis of amyloid precursor protein in microglial cells.

Mönning U, Sandbrink R, Weidemann A, Banati RB, Masters CL, Beyreuther K.

J Biol Chem. 1995 Mar 31;270(13):7104-10.

11.

Age-associated memory impairment and early Alzheimer's disease. Only time will tell the difference.

Förstl H, Hentschel F, Sattel H, Geiger-Kabisch C, Besthorn C, Czech C, Mönning U, Beyreuther K.

Arzneimittelforschung. 1995 Mar;45(3A):394-7.

PMID:
7763332
12.

[Apolipoprotein E and Alzheimer dementia. Personal results and brief literature review].

Förstl H, Czech C, Sattel H, Geiger-Kabisch C, Besthorn C, Kreger S, Mönning U, Hartmann T, Masters C, Beyreuther K.

Nervenarzt. 1994 Nov;65(11):780-6. Review. German.

PMID:
7816155
13.

Amyloid precursor protein secretion and beta A4 amyloid generation are not mutually exclusive.

Dyrks T, Mönning U, Beyreuther K, Turner J.

FEBS Lett. 1994 Aug 1;349(2):210-4.

14.

Transforming growth factor beta mediates increase of mature transmembrane amyloid precursor protein in microglial cells.

Mönning U, Sandbrink R, Banati RB, Masters CL, Beyreuther K.

FEBS Lett. 1994 Apr 11;342(3):267-72.

15.

Amyloid precursor protein (APP) as a microglial acute phase protein.

Banati RB, Gehrmann J, Mönning U, Czech C, Beyreuther K, Kreutzberg GW.

Neuropathol Appl Neurobiol. 1994 Apr;20(2):194-5. No abstract available.

PMID:
7521020
16.

Apolipoprotein E-4 gene dose in clinically diagnosed Alzheimer's disease: prevalence, plasma cholesterol levels and cerebrovascular change.

Czech C, Förstl H, Hentschel F, Mönning U, Besthorn C, Geiger-Kabisch C, Sattel H, Masters C, Beyreuther K.

Eur Arch Psychiatry Clin Neurosci. 1994;243(5):291-2.

PMID:
8172944
17.

Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11.

Hilbich C, Mönning U, Grund C, Masters CL, Beyreuther K.

J Biol Chem. 1993 Dec 15;268(35):26571-7.

18.

Generation of beta A4 from the amyloid protein precursor and fragments thereof.

Dyrks T, Dyrks E, Mönning U, Urmoneit B, Turner J, Beyreuther K.

FEBS Lett. 1993 Nov 29;335(1):89-93.

19.

APP expression in primary neuronal cell cultures from P6 mice during in vitro differentiation.

Dichgans M, Mönning U, König G, Sandbrink R, Masters CL, Beyreuther K.

Dementia. 1993 Nov-Dec;4(6):301-7.

PMID:
8136892
20.

Early and rapid de novo synthesis of Alzheimer beta A4-amyloid precursor protein (APP) in activated microglia.

Banati RB, Gehrmann J, Czech C, Mönning U, Jones LL, König G, Beyreuther K, Kreutzberg GW.

Glia. 1993 Nov;9(3):199-210.

PMID:
7507467
21.

Regulation and expression of the Alzheimer's beta/A4 amyloid protein precursor in health, disease, and Down's syndrome.

Beyreuther K, Pollwein P, Multhaup G, Mönning U, König G, Dyrks T, Schubert W, Masters CL.

Ann N Y Acad Sci. 1993 Sep 24;695:91-102. Review.

PMID:
8239320
22.

Alzheimer beta A4-amyloid protein precursor in immunocompetent cells.

Mönning U, König G, Banati RB, Mechler H, Czech C, Gehrmann J, Schreiter-Gasser U, Masters CL, Beyreuther K.

J Biol Chem. 1992 Nov 25;267(33):23950-6.

23.

Identification and differential expression of a novel alternative splice isoform of the beta A4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells.

König G, Mönning U, Czech C, Prior R, Banati R, Schreiter-Gasser U, Bauer J, Masters CL, Beyreuther K.

J Biol Chem. 1992 May 25;267(15):10804-9.

24.

Amyloid precursor protein (APP) and beta A4 amyloid in Alzheimer's disease and Down syndrome.

Beyreuther K, Dyrks T, Hilbich C, Mönning U, König G, Multhaup G, Pollwein P, Masters CL.

Prog Clin Biol Res. 1992;379:159-82. Review. No abstract available.

PMID:
1409743
25.

In-vitro matured human macrophages express Alzheimer's beta A4-amyloid precursor protein indicating synthesis in microglial cells.

Bauer J, König G, Strauss S, Jonas U, Ganter U, Weidemann A, Mönning U, Masters CL, Volk B, Berger M, et al.

FEBS Lett. 1991 May 6;282(2):335-40.

26.

Quantitative changes in the amyloid beta A4 precursor protein in Alzheimer cerebrospinal fluid.

Prior R, Mönning U, Schreiter-Gasser U, Weidemann A, Blennow K, Gottfries CG, Masters CL, Beyreuther K.

Neurosci Lett. 1991 Mar 11;124(1):69-73.

PMID:
1677459
27.

Mechanisms of amyloid deposition in Alzheimer's disease.

Beyreuther K, Bush AI, Dyrks T, Hilbich C, König G, Mönning U, Multhaup G, Prior R, Rumble B, Schubert W, et al.

Ann N Y Acad Sci. 1991;640:129-39. Review.

PMID:
1776729
28.

Synthesis and secretion of Alzheimer amyloid beta A4 precursor protein by stimulated human peripheral blood leucocytes.

Mönning U, König G, Prior R, Mechler H, Schreiter-Gasser U, Masters CL, Beyreuther K.

FEBS Lett. 1990 Dec 17;277(1-2):261-6.

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