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Items: 34

1.

Association of Selenoprotein and Selenium Pathway Genotypes with Risk of Colorectal Cancer and Interaction with Selenium Status.

Fedirko V, Jenab M, Méplan C, Jones JS, Zhu W, Schomburg L, Siddiq A, Hybsier S, Overvad K, Tjønneland A, Omichessan H, Perduca V, Boutron-Ruault MC, Kühn T, Katzke V, Aleksandrova K, Trichopoulou A, Karakatsani A, Kotanidou A, Tumino R, Panico S, Masala G, Agnoli C, Naccarati A, Bueno-de-Mesquita B, Vermeulen RCH, Weiderpass E, Skeie G, Nøst TH, Lujan-Barroso L, Quirós JR, Huerta JM, Rodríguez-Barranco M, Barricarte A, Gylling B, Harlid S, Bradbury KE, Wareham N, Khaw KT, Gunter M, Murphy N, Freisling H, Tsilidis K, Aune D, Riboli E, Hesketh JE, Hughes DJ.

Nutrients. 2019 Apr 25;11(4). pii: E935. doi: 10.3390/nu11040935.

2.

Association of Single Nucleotide Polymorphisms in Selenoprotein Genes with Cancer Risk.

Méplan C.

Methods Mol Biol. 2018;1661:313-324. doi: 10.1007/978-1-4939-7258-6_22.

PMID:
28917054
3.

Modeling and gene knockdown to assess the contribution of nonsense-mediated decay, premature termination, and selenocysteine insertion to the selenoprotein hierarchy.

Zupanic A, Meplan C, Huguenin GV, Hesketh JE, Shanley DP.

RNA. 2016 Jul;22(7):1076-84. doi: 10.1261/rna.055749.115. Epub 2016 May 20.

4.

Transcriptomics and proteomics show that selenium affects inflammation, cytoskeleton, and cancer pathways in human rectal biopsies.

Méplan C, Johnson IT, Polley AC, Cockell S, Bradburn DM, Commane DM, Arasaradnam RP, Mulholland F, Zupanic A, Mathers JC, Hesketh J.

FASEB J. 2016 Aug;30(8):2812-25. doi: 10.1096/fj.201600251R. Epub 2016 Apr 21.

5.

Selenium and chronic diseases: a nutritional genomics perspective.

Méplan C.

Nutrients. 2015 May 15;7(5):3621-51. doi: 10.3390/nu7053621. Review.

6.

Association between maternal micronutrient status, oxidative stress, and common genetic variants in antioxidant enzymes at 15 weeks׳ gestation in nulliparous women who subsequently develop preeclampsia.

Mistry HD, Gill CA, Kurlak LO, Seed PT, Hesketh JE, Méplan C, Schomburg L, Chappell LC, Morgan L, Poston L; SCOPE Consortium.

Free Radic Biol Med. 2015 Jan;78:147-55. doi: 10.1016/j.freeradbiomed.2014.10.580. Epub 2014 Nov 6.

7.

Detecting translational regulation by change point analysis of ribosome profiling data sets.

Zupanic A, Meplan C, Grellscheid SN, Mathers JC, Kirkwood TB, Hesketh JE, Shanley DP.

RNA. 2014 Oct;20(10):1507-18. doi: 10.1261/rna.045286.114. Epub 2014 Aug 21.

8.

Selenium status is associated with colorectal cancer risk in the European prospective investigation of cancer and nutrition cohort.

Hughes DJ, Fedirko V, Jenab M, Schomburg L, Méplan C, Freisling H, Bueno-de-Mesquita HB, Hybsier S, Becker NP, Czuban M, Tjønneland A, Outzen M, Boutron-Ruault MC, Racine A, Bastide N, Kühn T, Kaaks R, Trichopoulos D, Trichopoulou A, Lagiou P, Panico S, Peeters PH, Weiderpass E, Skeie G, Dagrun E, Chirlaque MD, Sánchez MJ, Ardanaz E, Ljuslinder I, Wennberg M, Bradbury KE, Vineis P, Naccarati A, Palli D, Boeing H, Overvad K, Dorronsoro M, Jakszyn P, Cross AJ, Quirós JR, Stepien M, Kong SY, Duarte-Salles T, Riboli E, Hesketh JE.

Int J Cancer. 2015 Mar 1;136(5):1149-61. doi: 10.1002/ijc.29071. Epub 2014 Jul 21.

9.

Selenium and cancer: a story that should not be forgotten-insights from genomics.

Méplan C, Hesketh J.

Cancer Treat Res. 2014;159:145-66. doi: 10.1007/978-3-642-38007-5_9. Review.

PMID:
24114479
10.

Association between polymorphisms in glutathione peroxidase and selenoprotein P genes, glutathione peroxidase activity, HRT use and breast cancer risk.

Méplan C, Dragsted LO, Ravn-Haren G, Tjønneland A, Vogel U, Hesketh J.

PLoS One. 2013 Sep 10;8(9):e73316. doi: 10.1371/journal.pone.0073316. eCollection 2013.

11.

Polymorphisms in thioredoxin reductase and selenoprotein K genes and selenium status modulate risk of prostate cancer.

Méplan C, Rohrmann S, Steinbrecher A, Schomburg L, Jansen E, Linseisen J, Hesketh J.

PLoS One. 2012;7(11):e48709. doi: 10.1371/journal.pone.0048709. Epub 2012 Nov 1.

12.

The influence of selenium and selenoprotein gene variants on colorectal cancer risk.

Méplan C, Hesketh J.

Mutagenesis. 2012 Mar;27(2):177-86. doi: 10.1093/mutage/ger058. Review.

PMID:
22294765
13.

Marginal selenium deficiency down-regulates inflammation-related genes in splenic leukocytes of the mouse.

Kipp AP, Banning A, van Schothorst EM, Méplan C, Coort SL, Evelo CT, Keijer J, Hesketh J, Brigelius-Flohé R.

J Nutr Biochem. 2012 Sep;23(9):1170-7. doi: 10.1016/j.jnutbio.2011.06.011. Epub 2011 Dec 1.

PMID:
22137268
14.

Differential effects of selenium and knock-down of glutathione peroxidases on TNFα and flagellin inflammatory responses in gut epithelial cells.

Gong G, Méplan C, Gautrey H, Hall J, Hesketh JE.

Genes Nutr. 2012 Apr;7(2):167-78. doi: 10.1007/s12263-011-0256-4. Epub 2011 Nov 9.

15.
16.

Polymorphisms affecting trace element bioavailability.

Mathers JC, Méplan C, Hesketh JE.

Int J Vitam Nutr Res. 2010 Oct;80(4-5):314-8. doi: 10.1024/0300-9831/a000039. Review.

PMID:
21462115
17.

The Micronutrient Genomics Project: a community-driven knowledge base for micronutrient research.

van Ommen B, El-Sohemy A, Hesketh J, Kaput J, Fenech M, Evelo CT, McArdle HJ, Bouwman J, Lietz G, Mathers JC, Fairweather-Tait S, van Kranen H, Elliott R, Wopereis S, Ferguson LR, Méplan C, Perozzi G, Allen L, Rivero D; Micronutrient Genomics Project Working Group.

Genes Nutr. 2010 Dec;5(4):285-96. doi: 10.1007/s12263-010-0192-8. Epub 2010 Oct 30.

18.

Trace elements and ageing, a genomic perspective using selenium as an example.

Méplan C.

J Trace Elem Med Biol. 2011 Jan;25 Suppl 1:S11-6. doi: 10.1016/j.jtemb.2010.10.002. Epub 2010 Dec 9. Review.

PMID:
21145717
19.

Effects of selenium status and polymorphisms in selenoprotein genes on prostate cancer risk in a prospective study of European men.

Steinbrecher A, Méplan C, Hesketh J, Schomburg L, Endermann T, Jansen E, Akesson B, Rohrmann S, Linseisen J.

Cancer Epidemiol Biomarkers Prev. 2010 Nov;19(11):2958-68. doi: 10.1158/1055-9965.EPI-10-0364. Epub 2010 Sep 17.

20.

Genetic variants in selenoprotein genes increase risk of colorectal cancer.

Méplan C, Hughes DJ, Pardini B, Naccarati A, Soucek P, Vodickova L, Hlavatá I, Vrána D, Vodicka P, Hesketh JE.

Carcinogenesis. 2010 Jun;31(6):1074-9. doi: 10.1093/carcin/bgq076. Epub 2010 Apr 8.

PMID:
20378690
21.

Four selenoproteins, protein biosynthesis, and Wnt signalling are particularly sensitive to limited selenium intake in mouse colon.

Kipp A, Banning A, van Schothorst EM, Méplan C, Schomburg L, Evelo C, Coort S, Gaj S, Keijer J, Hesketh J, Brigelius-Flohé R.

Mol Nutr Food Res. 2009 Dec;53(12):1561-72. doi: 10.1002/mnfr.200900105.

PMID:
19810021
22.

Relative abundance of selenoprotein P isoforms in human plasma depends on genotype, se intake, and cancer status.

Méplan C, Nicol F, Burtle BT, Crosley LK, Arthur JR, Mathers JC, Hesketh JE.

Antioxid Redox Signal. 2009 Nov;11(11):2631-40. doi: 10.1089/ARS.2009.2533.

PMID:
19453253
23.

Two common single nucleotide polymorphisms in the gene encoding beta-carotene 15,15'-monoxygenase alter beta-carotene metabolism in female volunteers.

Leung WC, Hessel S, Méplan C, Flint J, Oberhauser V, Tourniaire F, Hesketh JE, von Lintig J, Lietz G.

FASEB J. 2009 Apr;23(4):1041-53. doi: 10.1096/fj.08-121962. Epub 2008 Dec 22.

PMID:
19103647
24.

Functional effects of a common single-nucleotide polymorphism (GPX4c718t) in the glutathione peroxidase 4 gene: interaction with sex.

Méplan C, Crosley LK, Nicol F, Horgan GW, Mathers JC, Arthur JR, Hesketh JE.

Am J Clin Nutr. 2008 Apr;87(4):1019-27.

PMID:
18400727
25.

Supplementation of healthy volunteers with nutritionally relevant amounts of selenium increases the expression of lymphocyte protein biosynthesis genes.

Pagmantidis V, Méplan C, van Schothorst EM, Keijer J, Hesketh JE.

Am J Clin Nutr. 2008 Jan;87(1):181-9.

PMID:
18175754
26.

Genetic polymorphisms in the human selenoprotein P gene determine the response of selenoprotein markers to selenium supplementation in a gender-specific manner (the SELGEN study).

Méplan C, Crosley LK, Nicol F, Beckett GJ, Howie AF, Hill KE, Horgan G, Mathers JC, Arthur JR, Hesketh JE.

FASEB J. 2007 Oct;21(12):3063-74. Epub 2007 May 29.

PMID:
17536041
27.

Differential regulation of expression of cytosolic and mitochondrial thioredoxin reductase in rat liver and kidney.

Crosley LK, Méplan C, Nicol F, Rundlöf AK, Arnér ES, Hesketh JE, Arthur JR.

Arch Biochem Biophys. 2007 Mar 15;459(2):178-88. Epub 2007 Jan 22.

PMID:
17291446
28.

Effects of tobacco smoke and benzo[a]pyrene on human endothelial cell and monocyte stress responses.

Vayssier-Taussat M, Camilli T, Aron Y, Meplan C, Hainaut P, Polla BS, Weksler B.

Am J Physiol Heart Circ Physiol. 2001 Mar;280(3):H1293-300.

30.

Redox signalling and transition metals in the control of the p53 pathway.

Méplan C, Richard MJ, Hainaut P.

Biochem Pharmacol. 2000 Jan 1;59(1):25-33. Review.

PMID:
10605931
31.

Metal ions as regulators of the conformation and function of the tumour suppressor protein p53: implications for carcinogenesis.

Méplan C, Verhaegh G, Richard MJ, Hainaut P.

Proc Nutr Soc. 1999 Aug;58(3):565-71. Review.

PMID:
10604188
32.
33.

Impairment of cultured cell proliferation and metallothionein expression by metal chelator NNN'N'-tetrakis-(2-pyridylmethyl)ethylene diamine.

Parat MO, Richard MJ, Meplan C, Favier A, Béani JC.

Biol Trace Elem Res. 1999 Oct;70(1):51-68.

PMID:
10493184
34.

S-phase-dependent action of cycloheximide in relieving chromatin-mediated general transcriptional repression.

Cesari M, Héliot L, Meplan C, Pabion M, Khochbin S.

Biochem J. 1998 Dec 15;336 ( Pt 3):619-24.

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