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Items: 1 to 50 of 82

1.

Whole-exome sequencing suggests multiallelic inheritance for childhood-onset Ménière's disease.

Skarp S, Kanervo L, Kotimäki J, Sorri M, Männikkö M, Hietikko E.

Ann Hum Genet. 2019 May 20. doi: 10.1111/ahg.12327. [Epub ahead of print]

PMID:
31106404
2.

Exploring the role of genetic confounding in the association between maternal and offspring body mass index: evidence from three birth cohorts.

Bond TA, Karhunen V, Wielscher M, Auvinen J, Männikkö M, Keinänen-Kiukaanniemi S, Gunter MJ, Felix JF, Prokopenko I, Yang J, Visscher PM, Evans DM, Sebert S, Lewin A, O'Reilly PF, Lawlor DA, Jarvelin MR.

Int J Epidemiol. 2019 May 10. pii: dyz095. doi: 10.1093/ije/dyz095. [Epub ahead of print]

PMID:
31074781
3.

Genome-wide meta-analysis identifies genetic locus on chromosome 9 associated with Modic changes.

Freidin M, Kraatari M, Skarp S, Määttä J, Kettunen J, Niinimäki J, Karppinen J, Williams F, Männikkö M.

J Med Genet. 2019 Feb 26. pii: jmedgenet-2018-105726. doi: 10.1136/jmedgenet-2018-105726. [Epub ahead of print]

PMID:
30808802
4.

Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics.

Tynkkynen T, Wang Q, Ekholm J, Anufrieva O, Ohukainen P, Vepsäläinen J, Männikkö M, Keinänen-Kiukaanniemi S, Holmes MV, Goodwin M, Ring S, Chambers JC, Kooner J, Järvelin MR, Kettunen J, Hill M, Davey Smith G, Ala-Korpela M.

Int J Epidemiol. 2019 Jan 25. doi: 10.1093/ije/dyy287. [Epub ahead of print]

5.

Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland.

Kurki MI, Saarentaus E, Pietiläinen O, Gormley P, Lal D, Kerminen S, Torniainen-Holm M, Hämäläinen E, Rahikkala E, Keski-Filppula R, Rauhala M, Korpi-Heikkilä S, Komulainen-Ebrahim J, Helander H, Vieira P, Männikkö M, Peltonen M, Havulinna AS, Salomaa V, Pirinen M, Suvisaari J, Moilanen JS, Körkkö J, Kuismin O, Daly MJ, Palotie A.

Nat Commun. 2019 Jan 24;10(1):410. doi: 10.1038/s41467-018-08262-y.

6.

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.

Karlsson Linnér R, Biroli P, Kong E, Meddens SFW, Wedow R, Fontana MA, Lebreton M, Tino SP, Abdellaoui A, Hammerschlag AR, Nivard MG, Okbay A, Rietveld CA, Timshel PN, Trzaskowski M, Vlaming R, Zünd CL, Bao Y, Buzdugan L, Caplin AH, Chen CY, Eibich P, Fontanillas P, Gonzalez JR, Joshi PK, Karhunen V, Kleinman A, Levin RZ, Lill CM, Meddens GA, Muntané G, Sanchez-Roige S, Rooij FJV, Taskesen E, Wu Y, Zhang F; 23and Me Research Team; eQTLgen Consortium; International Cannabis Consortium; Social Science Genetic Association Consortium, Auton A, Boardman JD, Clark DW, Conlin A, Dolan CC, Fischbacher U, Groenen PJF, Harris KM, Hasler G, Hofman A, Ikram MA, Jain S, Karlsson R, Kessler RC, Kooyman M, MacKillop J, Männikkö M, Morcillo-Suarez C, McQueen MB, Schmidt KM, Smart MC, Sutter M, Thurik AR, Uitterlinden AG, White J, Wit H, Yang J, Bertram L, Boomsma DI, Esko T, Fehr E, Hinds DA, Johannesson M, Kumari M, Laibson D, Magnusson PKE, Meyer MN, Navarro A, Palmer AA, Pers TH, Posthuma D, Schunk D, Stein MB, Svento R, Tiemeier H, Timmers PRHJ, Turley P, Ursano RJ, Wagner GG, Wilson JF, Gratten J, Lee JJ, Cesarini D, Benjamin DJ, Koellinger PD, Beauchamp JP.

Nat Genet. 2019 Feb;51(2):245-257. doi: 10.1038/s41588-018-0309-3. Epub 2019 Jan 14.

PMID:
30643258
7.

Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment.

Sliz E, Kettunen J, Holmes MV, Williams CO, Boachie C, Wang Q, Männikkö M, Sebert S, Walters R, Lin K, Millwood IY, Clarke R, Li L, Rankin N, Welsh P, Delles C, Jukema JW, Trompet S, Ford I, Perola M, Salomaa V, Järvelin MR, Chen Z, Lawlor DA, Ala-Korpela M, Danesh J, Davey Smith G, Sattar N, Butterworth A, Würtz P.

Circulation. 2018 Nov 27;138(22):2499-2512. doi: 10.1161/CIRCULATIONAHA.118.034942. Epub 2018 Aug 15.

PMID:
30524137
8.

Metabolomic Consequences of Genetic Inhibition of PCSK9 Compared With Statin Treatment

Sliz E, Kettunen J, Holmes MV, Williams CO, Boachie C, Wang Q, Männikkö M, Sebert S, Walters R, Lin K, Millwood LY, Clarke R, Li L, Rankin N, Welsh P, Delles C, Jukema JW, Trompet S, Ford I, Perola M, Salomaa V, Järvelin MR, Chen Z, Lawlor DA, Ala-Korpela M, Danesh J, Smith GD, Sattar N, Butterworth A, Würtz P.

Circulation. 2018 Nov 27;138(22):2499–2512.

9.

Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males.

Smith SB, Parisien M, Bair E, Belfer I, Chabot-Doré AJ, Gris P, Khoury S, Tansley S, Torosyan Y, Zaykin DV, Bernhardt O, de Oliveira Serrano P, Gracely RH, Jain D, Järvelin MR, Kaste LM, Kerr KF, Kocher T, Lähdesmäki R, Laniado N, Laurie CC, Laurie CA, Männikkö M, Meloto CB, Nackley AG, Nelson SC, Pesonen P, Ribeiro-Dasilva MC, Rizzatti-Barbosa CM, Sanders AE, Schwahn C, Sipilä K, Sofer T, Teumer A, Mogil JS, Fillingim RB, Greenspan JD, Ohrbach R, Slade GD, Maixner W, Diatchenko L.

Pain. 2019 Mar;160(3):579-591. doi: 10.1097/j.pain.0000000000001438.

10.

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families.

Gormley P, Kurki MI, Hiekkala ME, Veerapen K, Häppölä P, Mitchell AA, Lal D, Palta P, Surakka I, Kaunisto MA, Hämäläinen E, Vepsäläinen S, Havanka H, Harno H, Ilmavirta M, Nissilä M, Säkö E, Sumelahti ML, Liukkonen J, Sillanpää M, Metsähonkala L, Koskinen S, Lehtimäki T, Raitakari O, Männikkö M, Ran C, Belin AC, Jousilahti P, Anttila V, Salomaa V, Artto V, Färkkilä M; 23andMe Research Team; International Headache Genetics Consortium (IHGC), Runz H, Daly MJ, Neale BM, Ripatti S, Kallela M, Wessman M, Palotie A.

Neuron. 2018 Sep 5;99(5):1098. doi: 10.1016/j.neuron.2018.08.029. No abstract available.

PMID:
30189203
11.

Whole exome sequencing in Finnish families identifies new candidate genes for osteoarthritis.

Skarp S, Kämäräinen OP, Wei GH, Jakkula E, Kiviranta I, Kröger H, Auvinen J, Lehenkari P, Ala-Kokko L, Männikkö M.

PLoS One. 2018 Aug 29;13(8):e0203313. doi: 10.1371/journal.pone.0203313. eCollection 2018.

12.

Rare Copy Number Variants in Array-Based Comparative Genomic Hybridization in Early-Onset Skeletal Fragility.

Costantini A, Skarp S, Kämpe A, Mäkitie RE, Pettersson M, Männikkö M, Jiao H, Taylan F, Lindstrand A, Mäkitie O.

Front Endocrinol (Lausanne). 2018 Jul 10;9:380. doi: 10.3389/fendo.2018.00380. eCollection 2018.

13.

Genome-Wide Association Study of Erosive Tooth Wear in a Finnish Cohort.

Alaraudanjoki VK, Koivisto S, Pesonen P, Männikkö M, Leinonen J, Tjäderhane L, Laitala ML, Lussi A, Anttonen VA.

Caries Res. 2019;53(1):49-59. doi: 10.1159/000488208. Epub 2018 Jun 13.

PMID:
29898447
14.

Early determinants of metabolically healthy obesity in young adults: study of the Northern Finland Birth Cohort 1966.

Nedelec R, Jokelainen J, Miettunen J, Ruokonen A, Herzig KH, Männikkö M, Järvelin MR, Sebert S.

Int J Obes (Lond). 2018 Oct;42(10):1704-1714. doi: 10.1038/s41366-018-0115-0. Epub 2018 May 24.

15.

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families.

Gormley P, Kurki MI, Hiekkala ME, Veerapen K, Häppölä P, Mitchell AA, Lal D, Palta P, Surakka I, Kaunisto MA, Hämäläinen E, Vepsäläinen S, Havanka H, Harno H, Ilmavirta M, Nissilä M, Säkö E, Sumelahti ML, Liukkonen J, Sillanpää M, Metsähonkala L, Koskinen S, Lehtimäki T, Raitakari O, Männikkö M, Ran C, Belin AC, Jousilahti P, Anttila V, Salomaa V, Artto V, Färkkilä M; 23andMe Research Team; International Headache Genetics Consortium (IHGC), Runz H, Daly MJ, Neale BM, Ripatti S, Kallela M, Wessman M, Palotie A.

Neuron. 2018 May 16;98(4):743-753.e4. doi: 10.1016/j.neuron.2018.04.014. Epub 2018 May 3. Erratum in: Neuron. 2018 Sep 5;99(5):1098.

16.

Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland.

Martin AR, Karczewski KJ, Kerminen S, Kurki MI, Sarin AP, Artomov M, Eriksson JG, Esko T, Genovese G, Havulinna AS, Kaprio J, Konradi A, Korányi L, Kostareva A, Männikkö M, Metspalu A, Perola M, Prasad RB, Raitakari O, Rotar O, Salomaa V, Groop L, Palotie A, Neale BM, Ripatti S, Pirinen M, Daly MJ.

Am J Hum Genet. 2018 May 3;102(5):760-775. doi: 10.1016/j.ajhg.2018.03.003. Epub 2018 Apr 26.

17.

A GWAS meta-analysis from 5 population-based cohorts implicates ion channel genes in the pathogenesis of irritable bowel syndrome.

Bonfiglio F, Henström M, Nag A, Hadizadeh F, Zheng T, Cenit MC, Tigchelaar E, Williams F, Reznichenko A, Ek WE, Rivera NV, Homuth G, Aghdassi AA, Kacprowski T, Männikkö M, Karhunen V, Bujanda L, Rafter J, Wijmenga C, Ronkainen J, Hysi P, Zhernakova A, D'Amato M.

Neurogastroenterol Motil. 2018 Sep;30(9):e13358. doi: 10.1111/nmo.13358. Epub 2018 Apr 19.

PMID:
29673008
18.

NAFLD risk alleles in PNPLA3, TM6SF2, GCKR and LYPLAL1 show divergent metabolic effects.

Sliz E, Sebert S, Würtz P, Kangas AJ, Soininen P, Lehtimäki T, Kähönen M, Viikari J, Männikkö M, Ala-Korpela M, Raitakari OT, Kettunen J.

Hum Mol Genet. 2018 Jun 15;27(12):2214-2223. doi: 10.1093/hmg/ddy124.

19.

Genome-Wide Association Study Implicates Atrial Natriuretic Peptide Rather Than B-Type Natriuretic Peptide in the Regulation of Blood Pressure in the General Population.

Salo PP, Havulinna AS, Tukiainen T, Raitakari O, Lehtimäki T, Kähönen M, Kettunen J, Männikkö M, Eriksson JG, Jula A, Blankenberg S, Zeller T, Salomaa V, Kristiansson K, Perola M.

Circ Cardiovasc Genet. 2017 Dec;10(6). pii: e001713. doi: 10.1161/CIRCGENETICS.117.001713.

20.

Functional polymorphisms in asporin and CILP together with joint loading predispose to hand osteoarthritis.

Taipale M, Solovieva S, Leino-Arjas P, Männikkö M.

BMC Genet. 2017 Dec 12;18(1):108. doi: 10.1186/s12863-017-0585-4.

21.

Concomitant diseases and their effect on disease prognosis in Meniere's disease: diabetes mellitus identified as a negative prognostic factor.

Pieskä T, Kotimäki J, Männikkö M, Sorri M, Hietikko E.

Acta Otolaryngol. 2018 Jan;138(1):36-40. doi: 10.1080/00016489.2017.1373850. Epub 2017 Sep 15.

PMID:
28914106
22.

TUFT1, a novel candidate gene for metatarsophalangeal osteoarthritis, plays a role in chondrogenesis on a calcium-related pathway.

Sliz E, Taipale M, Welling M, Skarp S, Alaraudanjoki V, Ignatius J, Ruddock L, Nissi R, Männikkö M.

PLoS One. 2017 Apr 14;12(4):e0175474. doi: 10.1371/journal.pone.0175474. eCollection 2017.

23.

Association between height and osteoarthritis of the knee and hip: The Northern Finland Birth Cohort 1966 Study.

Welling M, Auvinen J, Lehenkari P, Männikkö M, Karppinen J, Eskola PJ.

Int J Rheum Dis. 2017 Sep;20(9):1095-1104. doi: 10.1111/1756-185X.13059. Epub 2017 Mar 10.

PMID:
28296269
24.

GWAS Identifies New Loci for Painful Temporomandibular Disorder: Hispanic Community Health Study/Study of Latinos.

Sanders AE, Jain D, Sofer T, Kerr KF, Laurie CC, Shaffer JR, Marazita ML, Kaste LM, Slade GD, Fillingim RB, Ohrbach R, Maixner W, Kocher T, Bernhardt O, Teumer A, Schwahn C, Sipilä K, Lähdesmäki R, Männikkö M, Pesonen P, Järvelin M, Rizzatti-Barbosa CM, Meloto CB, Ribeiro-Dasilva M, Diatchenko L, Serrano P, Smith SB.

J Dent Res. 2017 Mar;96(3):277-284. doi: 10.1177/0022034516686562. Epub 2017 Jan 12.

25.

A Whole Exome Study Identifies Novel Candidate Genes for Vertebral Bone Marrow Signal Changes (Modic Changes).

Kraatari M, Skarp S, Niinimäki J, Karppinen J, Männikkö M.

Spine (Phila Pa 1976). 2017 Aug 15;42(16):1201-1206. doi: 10.1097/BRS.0000000000002049.

PMID:
27997510
26.

Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.

Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, Kallela M, Freilinger TM, Ran C, Gordon SG, Stam AH, Steinberg S, Borck G, Koiranen M, Quaye L, Adams HH, Lehtimäki T, Sarin AP, Wedenoja J, Hinds DA, Buring JE, Schürks M, Ridker PM, Hrafnsdottir MG, Stefansson H, Ring SM, Hottenga JJ, Penninx BW, Färkkilä M, Artto V, Kaunisto M, Vepsäläinen S, Malik R, Heath AC, Madden PA, Martin NG, Montgomery GW, Kurki MI, Kals M, Mägi R, Pärn K, Hämäläinen E, Huang H, Byrnes AE, Franke L, Huang J, Stergiakouli E, Lee PH, Sandor C, Webber C, Cader Z, Muller-Myhsok B, Schreiber S, Meitinger T, Eriksson JG, Salomaa V, Heikkilä K, Loehrer E, Uitterlinden AG, Hofman A, van Duijn CM, Cherkas L, Pedersen LM, Stubhaug A, Nielsen CS, Männikkö M, Mihailov E, Milani L, Göbel H, Esserlind AL, Christensen AF, Hansen TF, Werge T; International Headache Genetics Consortium, Kaprio J, Aromaa AJ, Raitakari O, Ikram MA, Spector T, Järvelin MR, Metspalu A, Kubisch C, Strachan DP, Ferrari MD, Belin AC, Dichgans M, Wessman M, van den Maagdenberg AM, Zwart JA, Boomsma DI, Smith GD, Stefansson K, Eriksson N, Daly MJ, Neale BM, Olesen J, Chasman DI, Nyholt DR, Palotie A.

Nat Genet. 2016 Sep 28;48(10):1296. doi: 10.1038/ng1016-1296c. No abstract available.

PMID:
27681292
27.

A meta-analysis of reflux genome-wide association studies in 6750 Northern Europeans from the general population.

Bonfiglio F, Hysi PG, Ek W, Karhunen V, Rivera NV, Männikkö M, Nordenstedt H, Zucchelli M, Bresso F, Williams F, Tornblom H, Magnusson PK, Pedersen NL, Ronkainen J, Schmidt PT, D'Amato M.

Neurogastroenterol Motil. 2017 Feb;29(2). doi: 10.1111/nmo.12923. Epub 2016 Aug 3.

PMID:
27485664
28.

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.

Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, Kallela M, Freilinger TM, Ran C, Gordon SG, Stam AH, Steinberg S, Borck G, Koiranen M, Quaye L, Adams HH, Lehtimäki T, Sarin AP, Wedenoja J, Hinds DA, Buring JE, Schürks M, Ridker PM, Hrafnsdottir MG, Stefansson H, Ring SM, Hottenga JJ, Penninx BW, Färkkilä M, Artto V, Kaunisto M, Vepsäläinen S, Malik R, Heath AC, Madden PA, Martin NG, Montgomery GW, Kurki MI, Kals M, Mägi R, Pärn K, Hämäläinen E, Huang H, Byrnes AE, Franke L, Huang J, Stergiakouli E, Lee PH, Sandor C, Webber C, Cader Z, Muller-Myhsok B, Schreiber S, Meitinger T, Eriksson JG, Salomaa V, Heikkilä K, Loehrer E, Uitterlinden AG, Hofman A, van Duijn CM, Cherkas L, Pedersen LM, Stubhaug A, Nielsen CS, Männikkö M, Mihailov E, Milani L, Göbel H, Esserlind AL, Christensen AF, Hansen TF, Werge T; International Headache Genetics Consortium, Kaprio J, Aromaa AJ, Raitakari O, Ikram MA, Spector T, Järvelin MR, Metspalu A, Kubisch C, Strachan DP, Ferrari MD, Belin AC, Dichgans M, Wessman M, van den Maagdenberg AM, Zwart JA, Boomsma DI, Smith GD, Stefansson K, Eriksson N, Daly MJ, Neale BM, Olesen J, Chasman DI, Nyholt DR, Palotie A.

Nat Genet. 2016 Aug;48(8):856-66. doi: 10.1038/ng.3598. Epub 2016 Jun 20. Erratum in: Nat Genet. 2016 Sep 28;48(10 ):1296.

29.

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.

Singh T, Kurki MI, Curtis D, Purcell SM, Crooks L, McRae J, Suvisaari J, Chheda H, Blackwood D, Breen G, Pietiläinen O, Gerety SS, Ayub M, Blyth M, Cole T, Collier D, Coomber EL, Craddock N, Daly MJ, Danesh J, DiForti M, Foster A, Freimer NB, Geschwind D, Johnstone M, Joss S, Kirov G, Körkkö J, Kuismin O, Holmans P, Hultman CM, Iyegbe C, Lönnqvist J, Männikkö M, McCarroll SA, McGuffin P, McIntosh AM, McQuillin A, Moilanen JS, Moore C, Murray RM, Newbury-Ecob R, Ouwehand W, Paunio T, Prigmore E, Rees E, Roberts D, Sambrook J, Sklar P, St Clair D, Veijola J, Walters JT, Williams H; Swedish Schizophrenia Study; INTERVAL Study; DDD Study; UK10 K Consortium, Sullivan PF, Hurles ME, O'Donovan MC, Palotie A, Owen MJ, Barrett JC.

Nat Neurosci. 2016 Apr;19(4):571-7. doi: 10.1038/nn.4267. Epub 2016 Mar 14.

PMID:
26974950
30.

Targeted re-sequencing of linkage region on 2q21 identifies a novel functional variant for hip and knee osteoarthritis.

Taipale M, Jakkula E, Kämäräinen OP, Gao P, Skarp S, Barral S, Kiviranta I, Kröger H, Ott J, Wei GH, Ala-Kokko L, Männikkö M.

Osteoarthritis Cartilage. 2016 Apr;24(4):655-63. doi: 10.1016/j.joca.2015.10.019. Epub 2015 Nov 19.

31.
32.

Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant.

Song YQ, Karasugi T, Cheung KM, Chiba K, Ho DW, Miyake A, Kao PY, Sze KL, Yee A, Takahashi A, Kawaguchi Y, Mikami Y, Matsumoto M, Togawa D, Kanayama M, Shi D, Dai J, Jiang Q, Wu C, Tian W, Wang N, Leong JC, Luk KD, Yip SP, Cherny SS, Wang J, Mundlos S, Kelempisioti A, Eskola PJ, Männikkö M, Mäkelä P, Karppinen J, Järvelin MR, O'Reilly PF, Kubo M, Kimura T, Kubo T, Toyama Y, Mizuta H, Cheah KS, Tsunoda T, Sham PC, Ikegawa S, Chan D.

J Clin Invest. 2013 Nov;123(11):4909-17.

33.

Genome-wide association studies of lumbar disc degeneration--are we there yet?

Eskola PJ, Männikkö M, Samartzis D, Karppinen J.

Spine J. 2014 Mar 1;14(3):479-82. doi: 10.1016/j.spinee.2013.07.437. Epub 2013 Nov 5. No abstract available.

PMID:
24210639
34.

High incidence of Meniere-like symptoms in relatives of Meniere patients in the areas of Oulu University Hospital and Kainuu Central Hospital in Finland.

Hietikko E, Kotimäki J, Sorri M, Männikkö M.

Eur J Med Genet. 2013 Jun;56(6):279-85. doi: 10.1016/j.ejmg.2013.03.010. Epub 2013 Mar 29.

PMID:
23542667
35.

Role of environmental factors and history of low back pain in sciatica symptoms among Finnish adolescents.

Karjalainen U, Paananen M, Okuloff A, Taimela S, Auvinen J, Männikkö M, Karppinen J.

Spine (Phila Pa 1976). 2013 Jun 1;38(13):1105-11. doi: 10.1097/BRS.0b013e318287fb3a.

PMID:
23354107
36.

Genetic association studies in lumbar disc degeneration: a systematic review.

Eskola PJ, Lemmelä S, Kjaer P, Solovieva S, Männikkö M, Tommerup N, Lind-Thomsen A, Husgafvel-Pursiainen K, Cheung KM, Chan D, Samartzis D, Karppinen J.

PLoS One. 2012;7(11):e49995. doi: 10.1371/journal.pone.0049995. Epub 2012 Nov 21.

37.

Gender difference in genetic association between IL1A variant and early lumbar disc degeneration: a three-year follow-up.

Eskola PJ, Kjaer P, Sorensen JS, Okuloff A, Wedderkopp N, Daavittila I, Ala-Kokko L, Männikkö M, Karppinen J.

Int J Mol Epidemiol Genet. 2012;3(3):195-204. Epub 2012 Aug 31.

38.

A replication study on proposed candidate genes in Ménière's disease, and a review of the current status of genetic studies.

Hietikko E, Kotimäki J, Okuloff A, Sorri M, Männikkö M.

Int J Audiol. 2012 Nov;51(11):841-5. doi: 10.3109/14992027.2012.705900. Epub 2012 Aug 30. Review.

PMID:
22934933
39.

Rare variations in WNT3A and DKK1 may predispose carriers to primary osteoporosis.

Korvala J, Löija M, Mäkitie O, Sochett E, Jüppner H, Schnabel D, Mora S, Cole WG, Ala-Kokko L, Männikkö M.

Eur J Med Genet. 2012 Oct;55(10):515-9. doi: 10.1016/j.ejmg.2012.06.011. Epub 2012 Jul 9.

PMID:
22789636
40.

Mutations in LRP5 cause primary osteoporosis without features of OI by reducing Wnt signaling activity.

Korvala J, Jüppner H, Mäkitie O, Sochett E, Schnabel D, Mora S, Bartels CF, Warman ML, Deraska D, Cole WG, Hartikka H, Ala-Kokko L, Männikkö M.

BMC Med Genet. 2012 Apr 10;13:26. doi: 10.1186/1471-2350-13-26.

41.

Genetic susceptibility of intervertebral disc degeneration among young Finnish adults.

Kelempisioti A, Eskola PJ, Okuloff A, Karjalainen U, Takatalo J, Daavittila I, Niinimäki J, Sequeiros RB, Tervonen O, Solovieva S, Kao PY, Song YQ, Cheung KM, Chan D, Ala-Kokko L, Järvelin MR, Karppinen J, Männikkö M.

BMC Med Genet. 2011 Nov 22;12:153. doi: 10.1186/1471-2350-12-153.

42.

Finnish familial Meniere disease is not linked to chromosome 12p12.3, and anticipation and cosegregation with migraine are not common findings.

Hietikko E, Kotimäki J, Kentala E, Klockars T, Sorri M, Männikkö M.

Genet Med. 2011 May;13(5):415-20. doi: 10.1097/GIM.0b013e3182091a41.

PMID:
21346584
43.

Candidate gene association study of magnetic resonance imaging-based hip osteoarthritis (OA): evidence for COL9A2 gene as a common predisposing factor for hip OA and lumbar disc degeneration.

Näkki A, Videman T, Kujala UM, Suhonen M, Männikkö M, Peltonen L, Battié MC, Kaprio J, Saarela J.

J Rheumatol. 2011 Apr;38(4):747-52. doi: 10.3899/jrheum.100080. Epub 2010 Dec 15.

PMID:
21159828
44.

Genetic predisposition for femoral neck stress fractures in military conscripts.

Korvala J, Hartikka H, Pihlajamäki H, Solovieva S, Ruohola JP, Sahi T, Barral S, Ott J, Ala-Kokko L, Männikkö M.

BMC Genet. 2010 Oct 21;11:95. doi: 10.1186/1471-2156-11-95.

45.

Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1.

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