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2.

Effect of three-year consumption of erythritol, xylitol and sorbitol candies on various plaque and salivary caries-related variables.

Runnel R, Mäkinen KK, Honkala S, Olak J, Mäkinen PL, Nõmmela R, Vahlberg T, Honkala E, Saag M.

J Dent. 2013 Dec;41(12):1236-44. doi: 10.1016/j.jdent.2013.09.007. Epub 2013 Oct 3.

PMID:
24095985
3.

Topical xylitol administration by parents for the promotion of oral health in infants: a caries prevention experiment at a Finnish Public Health Centre.

Mäkinen KK, Järvinen KL, Anttila CH, Luntamo LM, Vahlberg T.

Int Dent J. 2013 Aug;63(4):210-24. doi: 10.1111/idj.12038. Epub 2013 Apr 15.

PMID:
23879257
4.

Caries experience in the permanent dentition among first- and second-grade schoolchildren in southeastern Estonia.

Runnel R, Honkala S, Honkala E, Olak J, Nõmmela R, Vahlberg T, Mäkinen KK, Saag M.

Acta Odontol Scand. 2013 May-Jul;71(3-4):410-5. doi: 10.3109/00016357.2012.690529. Epub 2012 May 21.

PMID:
22607272
5.

Measuring Dental Caries in the Mixed Dentition by ICDAS.

Honkala E, Runnel R, Honkala S, Olak J, Vahlberg T, Saag M, Mäkinen KK.

Int J Dent. 2011;2011:150424. doi: 10.1155/2011/150424. Epub 2011 Oct 31.

6.

Sugar alcohol sweeteners as alternatives to sugar with special consideration of xylitol.

Mäkinen KK.

Med Princ Pract. 2011;20(4):303-20. doi: 10.1159/000324534. Epub 2011 May 11. Review.

7.

Sugar alcohols, caries incidence, and remineralization of caries lesions: a literature review.

Mäkinen KK.

Int J Dent. 2010;2010:981072. doi: 10.1155/2010/981072. Epub 2010 Jan 5.

8.

An end to crossover designs for studies on the effect of sugar substitutes on caries?

Mäkinen KK.

Caries Res. 2009;43(5):331-3. doi: 10.1159/000231568. Epub 2009 Aug 1.

PMID:
19648742
9.

Thirty-nine-month xylitol chewing-gum programme in initially 8-year-old school children: a feasibility study focusing on mutans streptococci and lactobacilli.

Mäkinen KK, Alanen P, Isokangas P, Isotupa K, Söderling E, Mäkinen PL, Wenhui W, Weijian W, Xiaochi C, Yi W, Boxue Z.

Int Dent J. 2008 Feb;58(1):41-50.

PMID:
18350853
10.

Similarity of the effects of erythritol and xylitol on some risk factors of dental caries.

Mäkinen KK, Saag M, Isotupa KP, Olak J, Nõmmela R, Söderling E, Mäkinen PL.

Caries Res. 2005 May-Jun;39(3):207-15.

PMID:
15914983
11.

Six-month polyol chewing-gum programme in kindergarten-age children: a feasibility study focusing on mutans streptococci and dental plaque.

Mäkinen KK, Isotupa KP, Mäkinen PL, Söderling E, Song KB, Nam SH, Jeong SH.

Int Dent J. 2005 Apr;55(2):81-8.

PMID:
15880962
12.

Xylitol for caries prevention.

Peldyak J, Mäkinen KK.

J Dent Hyg. 2002 Fall;76(4):276-85. Review.

PMID:
12592919
13.

The effect of polyol-combinant saliva stimulants on S. mutans levels in plaque and saliva of patients with mental retardation.

Mäkinen KK, Isotupa KP, Kivilompolo T, Mäkinen PL, Murtomaa S, Petäjä J, Toivanen J, Söderling E.

Spec Care Dentist. 2002 Sep-Oct;22(5):187-93.

14.

Comparison of erythritol and xylitol saliva stimulants in the control of dental plaque and mutans streptococci.

Mäkinen KK, Isotupa KP, Kivilompolo T, Mäkinen PL, Toivanen J, Söderling E.

Caries Res. 2001 Mar-Apr;35(2):129-35.

PMID:
11275673
15.

The rocky road of xylitol to its clinical application.

Mäkinen KK.

J Dent Res. 2000 Jun;79(6):1352-5. No abstract available.

PMID:
10890712
16.
17.

Xylitol-based caries prevention: is there enough evidence for the existence of a specific xylitol effect?

Mäkinen KK.

Oral Dis. 1998 Dec;4(4):226-30. Review. No abstract available.

PMID:
10200700
18.

The optimum time to initiate habitual xylitol gum-chewing for obtaining long-term caries prevention.

Hujoel PP, Mäkinen KK, Bennett CA, Isotupa KP, Isokangas PJ, Allen P, Mäkinen PL.

J Dent Res. 1999 Mar;78(3):797-803.

PMID:
10096456
19.

Physical, chemical, and histologic changes in dentin caries lesions of primary teeth induced by regular use of polyol chewing gums.

Mäkinen KK, Chiego DJ Jr, Allen P, Bennett C, Isotupa KP, Tiekso J, Mäkinen PL.

Acta Odontol Scand. 1998 Jun;56(3):148-56.

PMID:
9688223
20.

Polyol-combinant saliva stimulants: a 4-month pilot study in young adults.

Mäkinen KK, Olak J, Russak S, Saag M, Seedre T, Vasar R, Vihalemm T, Mikelsaar M, Mäkinen PL.

Acta Odontol Scand. 1998 Apr;56(2):90-4.

PMID:
9669459
21.

A descriptive report of the effects of a 16-month xylitol chewing-gum programme subsequent to a 40-month sucrose gum programme.

Mäkinen KK, Hujoel PP, Bennett CA, Isokangas P, Isotupa K, Pape HR Jr, Mäkinen PL.

Caries Res. 1998;32(2):107-12.

PMID:
9544858
22.
23.

Dietary xylitol, sorbitol and D-mannitol but not erythritol retard bone resorption in rats.

Mattila PT, Svanberg MJ, Mäkinen KK, Knuuttila ML.

J Nutr. 1996 Jul;126(7):1865-70.

PMID:
8683349
24.

Polyol-combinant saliva stimulants and oral health in Veterans Affairs patients--an exploratory study.

Mäkinen KK, Pemberton D, Mäkinen PL, Chen CY, Cole J, Hujoel PP, Lopatin D, Lambert P.

Spec Care Dentist. 1996 May-Jun;16(3):104-15.

25.

The peptidolytic capacity of the spirochete system.

Mäkinen KK, Mäkinen PL.

Med Microbiol Immunol. 1996 May;185(1):1-10. Review.

26.

Dietary shifts may explain the incidence of periodontitis in industrialized countries.

Sewón LA, Mäkinen KK.

Med Hypotheses. 1996 Mar;46(3):269-75.

PMID:
8676765
27.
28.

Conclusion and review of the Michigan Xylitol Programme (1986-1995) for the prevention of dental caries.

Mäkinen KK, Mäkinen PL, Pape HR Jr, Peldyak J, Hujoel P, Isotupa KP, Soderling E, Isokangas PJ, Allen P, Bennett C.

Int Dent J. 1996 Feb;46(1):22-34.

PMID:
8744914
29.

Polyol chewing gums and caries rates in primary dentition: a 24-month cohort study.

Mäkinen KK, Hujoel PP, Bennett CA, Isotupa KP, Mäkinen PL, Allen P.

Caries Res. 1996;30(6):408-17.

PMID:
8946097
30.

Properties of whole saliva and dental plaque in relation to 40-month consumption of chewing gums containing xylitol, sorbitol of sucrose.

Mäkinen KK, Chen CY, Mäkinen PL, Bennett CA, Isokangas PJ, Isotupa KP, Pape HR Jr.

Caries Res. 1996;30(3):180-8.

PMID:
8860027
31.

Analysis in gingival crevicular fluid of two oligopeptides derived from human hemoglobin beta-chain.

Mäkinen KK, Sewon L, Mäkinen Pl.

J Periodontal Res. 1996 Jan;31(1):43-6.

32.

Xylitol chewing gums and caries rates: a 40-month cohort study.

Mäkinen KK, Bennett CA, Hujoel PP, Isokangas PJ, Isotupa KP, Pape HR Jr, Mäkinen PL.

J Dent Res. 1995 Dec;74(12):1904-13.

PMID:
8600188
34.

Saliva stimulants and the oral health of geriatric patients.

Mäkinen KK, Pemberton D, Cole J, Mäkinen PL, Chen CY, Lambert P.

Adv Dent Res. 1995 Jul;9(2):125-6.

PMID:
7546130
35.

Effect of polyol gums on dental plaque in orthodontic patients.

Isotupa KP, Gunn S, Chen CY, Lopatin D, Mäkinen KK.

Am J Orthod Dentofacial Orthop. 1995 May;107(5):497-504.

PMID:
7733059
36.

Purification and general properties of an oligopeptidase from Treponema denticola ATCC 35405--a human oral spirochete.

Mäkinen KK, Mäkinen PL, Loesche WJ, Syed SA.

Arch Biochem Biophys. 1995 Feb 1;316(2):689-98.

PMID:
7864624
37.

Stabilisation of rampant caries: polyol gums and arrest of dentine caries in two long-term cohort studies in young subjects.

Mäkinen KK, Mäkinen PL, Pape HR Jr, Allen P, Bennett CA, Isokangas PJ, Isotupa KP.

Int Dent J. 1995 Feb;45(1 Suppl 1):93-107.

PMID:
7607749
38.

Do caries explorers transmit infections with persons? An evaluation of second molar caries onsets.

Hujoel PP, Mäkinen KK, Bennett CB, Isokangas PJ, Isotupa KP, Pape HR Jr, Lamont RJ, DeRouen TA, Davis S.

Caries Res. 1995;29(6):461-6.

PMID:
8556749
39.

Verification and maintenance of dental explorer sharpness.

Pape HR Jr, Mäkinen KK.

Oper Dent. 1994 Nov-Dec;19(6):221-3.

PMID:
9028241
42.

A re-analysis of caries rates in a preventive trial using Poisson regression models.

Hujoel PP, Isokangas PJ, Tiekso J, Davis S, Lamont RJ, DeRouen TA, Mäkinen KK.

J Dent Res. 1994 Feb;73(2):573-9.

PMID:
8120223
43.

Proteolytic and oxidoreductase activity of Treponema denticola ATCC 35405 grown in an aerobic and anaerobic gaseous environment.

Syed SA, Mäkinen KK, Mäkinen PL, Chen CY, Muhammad Z.

Res Microbiol. 1993 May;144(4):317-26.

44.

A dietary procedure for preventing dental caries in young adults.

Mäkinen KK.

J Am Coll Health. 1993 Jan;41(4):172-80. Review.

PMID:
8436732
45.

Dentistry in the future--on the role and goal of basic research in oral biology.

Mäkinen KK.

Proc Finn Dent Soc. 1993;89(1-2):5-14.

PMID:
8284302
46.
47.
48.
50.

Purification and characterization of a soluble endopeptidase from rat bone.

Bollen AM, Makinen KK.

Calcif Tissue Int. 1991 Feb;48(2):111-9.

PMID:
2013011

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