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Items: 1 to 50 of 81

1.

Ambivalence: A Key to Clinical Trial Participation?

Chilton JA, Rasmus ML, Lytton J, Kaplan CD, Jones LA, Hurd TC.

Front Oncol. 2018 Aug 10;8:300. doi: 10.3389/fonc.2018.00300. eCollection 2018. Review.

2.

Building trust and diversity in patient-centered oncology clinical trials: An integrated model.

Hurd TC, Kaplan CD, Cook ED, Chilton JA, Lytton JS, Hawk ET, Jones LA.

Clin Trials. 2017 Apr;14(2):170-179. doi: 10.1177/1740774516688860. Epub 2017 Feb 7. Review.

PMID:
28166647
3.

Reduced Protein Expression of the Na+/Ca2++K+-Exchanger (SLC24A4) in Apical Plasma Membranes of Maturation Ameloblasts of Fluorotic Mice.

Bronckers AL, Jalali R, Lytton J.

Calcif Tissue Int. 2017 Jan;100(1):80-86. doi: 10.1007/s00223-016-0197-4. Epub 2016 Oct 17.

4.

Anatomical evidence for a non-synaptic influence of the K+ -dependent Na+/Ca2+ -exchanger, NCKX2, on hippocampal plasticity.

Zhang Y, Sharma S, Lytton J.

Neuroscience. 2015 Dec 3;310:372-88. doi: 10.1016/j.neuroscience.2015.09.049. Epub 2015 Sep 26.

PMID:
26410028
5.

An essential role for the K+-dependent Na+/Ca2+-exchanger, NCKX4, in melanocortin-4-receptor-dependent satiety.

Li XF, Lytton J.

J Biol Chem. 2014 Sep 12;289(37):25445-59. doi: 10.1074/jbc.M114.564450. Epub 2014 Aug 5.

6.

Purinergic stimulation of K+-dependent Na+/Ca2+ exchanger isoform 4 requires dual activation by PKC and CaMKII.

Yang X, Lytton J.

Biosci Rep. 2013 Dec 19;33(6). pii: e00087. doi: 10.1042/BSR20130099.

7.

KIF21A-mediated axonal transport and selective endocytosis underlie the polarized targeting of NCKX2.

Lee KH, Lee JS, Lee D, Seog DH, Lytton J, Ho WK, Lee SH.

J Neurosci. 2012 Mar 21;32(12):4102-17. doi: 10.1523/JNEUROSCI.6331-11.2012.

8.

Determination of apparent calcium affinity for endogenously expressed human sarco(endo)plasmic reticulum calcium-ATPase isoform SERCA3.

Chandrasekera PC, Kargacin ME, Deans JP, Lytton J.

Am J Physiol Cell Physiol. 2009 May;296(5):C1105-14. doi: 10.1152/ajpcell.00650.2008. Epub 2009 Feb 18.

9.

A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage.

Cuomo O, Gala R, Pignataro G, Boscia F, Secondo A, Scorziello A, Pannaccione A, Viggiano D, Adornetto A, Molinaro P, Li XF, Lytton J, Di Renzo G, Annunziato L.

J Neurosci. 2008 Feb 27;28(9):2053-63. doi: 10.1523/JNEUROSCI.4912-07.2008.

10.

Na+/Ca2+ exchangers: three mammalian gene families control Ca2+ transport.

Lytton J.

Biochem J. 2007 Sep 15;406(3):365-82. Review.

PMID:
17716241
11.

K+ -dependent Na+/Ca2+ exchangers: key contributors to Ca2+ signaling.

Visser F, Lytton J.

Physiology (Bethesda). 2007 Jun;22:185-92. Review.

12.

Involvement of the potassium-dependent sodium/calcium exchanger gene product NCKX2 in the brain insult induced by permanent focal cerebral ischemia.

Cuomo O, Pignataro G, Gala R, Boscia F, Tortiglione A, Molinaro P, Di Renzo G, Lytton J, Annunziato L.

Ann N Y Acad Sci. 2007 Mar;1099:486-9.

PMID:
17446491
13.

Exchangers NCKX2, NCKX3, and NCKX4: identification of Thr-551 as a key residue in defining the apparent K(+) affinity of NCKX2.

Visser F, Valsecchi V, Annunziato L, Lytton J.

J Biol Chem. 2007 Feb 16;282(7):4453-62. Epub 2006 Dec 15.

14.

Protein kinase C-dependent enhancement of activity of rat brain NCKX2 heterologously expressed in HEK293 cells.

Lee JY, Visser F, Lee JS, Lee KH, Soh JW, Ho WK, Lytton J, Lee SH.

J Biol Chem. 2006 Dec 22;281(51):39205-16. Epub 2006 Oct 12.

15.

Metabolic regulation of sodium-calcium exchange by intracellular acyl CoAs.

Riedel MJ, Baczkó I, Searle GJ, Webster N, Fercho M, Jones L, Lang J, Lytton J, Dyck JR, Light PE.

EMBO J. 2006 Oct 4;25(19):4605-14. Epub 2006 Sep 14.

16.

Novel role for K+-dependent Na+/Ca2+ exchangers in regulation of cytoplasmic free Ca2+ and contractility in arterial smooth muscle.

Dong H, Jiang Y, Triggle CR, Li X, Lytton J.

Am J Physiol Heart Circ Physiol. 2006 Sep;291(3):H1226-35. Epub 2006 Apr 14.

17.

Importance of K+-dependent Na+/Ca2+-exchanger 2, NCKX2, in motor learning and memory.

Li XF, Kiedrowski L, Tremblay F, Fernandez FR, Perizzolo M, Winkfein RJ, Turner RW, Bains JS, Rancourt DE, Lytton J.

J Biol Chem. 2006 Mar 10;281(10):6273-82. Epub 2006 Jan 10.

19.
20.

The cation/Ca(2+) exchanger superfamily: phylogenetic analysis and structural implications.

Cai X, Lytton J.

Mol Biol Evol. 2004 Sep;21(9):1692-703. Epub 2004 May 26.

PMID:
15163769
21.

Molecular cloning of a sixth member of the K+-dependent Na+/Ca2+ exchanger gene family, NCKX6.

Cai X, Lytton J.

J Biol Chem. 2004 Feb 13;279(7):5867-76. Epub 2003 Nov 18.

22.

Store-operated cation entry mediated by CD20 in membrane rafts.

Li H, Ayer LM, Lytton J, Deans JP.

J Biol Chem. 2003 Oct 24;278(43):42427-34. Epub 2003 Aug 14.

23.

Inhibition of human SERCA3 by PL/IM430. Molecular analysis of the interaction.

Chandrasekera CP, Lytton J.

J Biol Chem. 2003 Apr 4;278(14):12482-8. Epub 2003 Jan 22.

24.

K+-dependent Na+/Ca2+ exchangers in the brain.

Lytton J, Li XF, Dong H, Kraev A.

Ann N Y Acad Sci. 2002 Nov;976:382-93.

PMID:
12502585
25.

Electrophysiological studies of the cloned rat cardiac NCX1.1 in transfected HEK cells: a focus on the stoichiometry.

Dong H, Dunn J, Lytton J.

Ann N Y Acad Sci. 2002 Nov;976:159-65. No abstract available.

PMID:
12502557
26.

Rat heart NCX1.1 stoichiometry measured in a transfected cell system.

Lytton J, Dong H.

Ann N Y Acad Sci. 2002 Nov;976:137-41.

PMID:
12502552
27.

Studies on the oligomeric state of the sodium/calcium + potassium exchanger NCKX2.

Yoo SS, Leach S, Lytton J.

Ann N Y Acad Sci. 2002 Nov;976:94-6. No abstract available.

PMID:
12502543
28.

Topological studies of the rat brain K+-dependent Na+/Ca2+ exchanger NCKX2.

Cai X, Zhang K, Lytton J.

Ann N Y Acad Sci. 2002 Nov;976:90-3. No abstract available.

PMID:
12502542
29.

Differential expression of Na/Ca exchanger and Na/Ca + K exchanger transcripts in rat brain.

Li XF, Lytton J.

Ann N Y Acad Sci. 2002 Nov;976:64-6. No abstract available.

PMID:
12502535
30.

How many sodium ions does it take to turn an exchanger?

Lytton J.

J Physiol. 2002 Dec 1;545(2):335. No abstract available.

31.

Molecular cloning of a fourth member of the potassium-dependent sodium-calcium exchanger gene family, NCKX4.

Li XF, Kraev AS, Lytton J.

J Biol Chem. 2002 Dec 13;277(50):48410-7. Epub 2002 Oct 11.

32.

A novel topology and redox regulation of the rat brain K+-dependent Na+/Ca2+ exchanger, NCKX2.

Cai X, Zhang K, Lytton J.

J Biol Chem. 2002 Dec 13;277(50):48923-30. Epub 2002 Oct 10.

33.

Effects of Na(+)/Ca(2+) exchanger downregulation on contractility and [Ca(2+)](i) transients in adult rat myocytes.

Tadros GM, Zhang XQ, Song J, Carl LL, Rothblum LI, Tian Q, Dunn J, Lytton J, Cheung JY.

Am J Physiol Heart Circ Physiol. 2002 Oct;283(4):H1616-26. Epub 2002 Jun 27.

34.

Preferential expression of plasmalemmal K-dependent Na+/Ca2+ exchangers in neurons versus astrocytes.

Kiedrowski L, Czyz A, Li XF, Lytton J.

Neuroreport. 2002 Aug 27;13(12):1529-32.

PMID:
12218699
35.

The molecular determinants of ionic regulatory differences between brain and kidney Na+/Ca2+ exchanger (NCX1) isoforms.

Dunn J, Elias CL, Le HD, Omelchenko A, Hryshko LV, Lytton J.

J Biol Chem. 2002 Sep 13;277(37):33957-62. Epub 2002 Jul 12.

36.
37.

Overexpression of Na+/Ca2+ exchanger alters contractility and SR Ca2+ content in adult rat myocytes.

Zhang XQ, Song J, Rothblum LI, Lun M, Wang X, Ding F, Dunn J, Lytton J, McDermott PJ, Cheung JY.

Am J Physiol Heart Circ Physiol. 2001 Nov;281(5):H2079-88.

38.

Electrophysiological characterization and ionic stoichiometry of the rat brain K(+)-dependent NA(+)/CA(2+) exchanger, NCKX2.

Dong H, Light PE, French RJ, Lytton J.

J Biol Chem. 2001 Jul 13;276(28):25919-28. Epub 2001 May 7.

39.

Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3.

Kraev A, Quednau BD, Leach S, Li XF, Dong H, Winkfein R, Perizzolo M, Cai X, Yang R, Philipson KD, Lytton J.

J Biol Chem. 2001 Jun 22;276(25):23161-72. Epub 2001 Apr 9. Erratum in: J Biol Chem. 2006 Mar 31;281(13):8996.

40.

Regulation of SERCA Ca2+ pump expression by cytoplasmic Ca2+ in vascular smooth muscle cells.

Wu KD, Bungard D, Lytton J.

Am J Physiol Cell Physiol. 2001 Apr;280(4):C843-51.

41.

Alternatively spliced isoforms of the rat eye sodium/calcium+potassium exchanger NCKX1.

Poon S, Leach S, Li XF, Tucker JE, Schnetkamp PP, Lytton J.

Am J Physiol Cell Physiol. 2000 Apr;278(4):C651-60.

42.

Physiological and molecular characterization of the Na+/Ca2+ exchanger in human platelets.

Kimura M, Jeanclos EM, Donnelly RJ, Lytton J, Reeves JP, Aviv A.

Am J Physiol. 1999 Sep;277(3):H911-7. doi: 10.1152/ajpheart.1999.277.3.H911.

PMID:
10484410
43.
44.

The relationship between Ca2+-ATPase and freely exchangeable Ca2+ in the dense tubules: a study in platelets from women.

Horiguchi M, Kimura M, Lytton J, Poch E, Aviv A.

Am J Hypertens. 1999 Feb;12(2 Pt 1):120-7.

PMID:
10090338
45.

A circularized sodium-calcium exchanger exon 2 transcript.

Li XF, Lytton J.

J Biol Chem. 1999 Mar 19;274(12):8153-60.

46.

Functional characterization of alternatively spliced human SERCA3 transcripts.

Poch E, Leach S, Snape S, Cacic T, MacLennan DH, Lytton J.

Am J Physiol. 1998 Dec;275(6):C1449-58. doi: 10.1152/ajpcell.1998.275.6.C1449.

PMID:
9843705
47.

Enhanced myocardial contractility and increased Ca2+ transport function in transgenic hearts expressing the fast-twitch skeletal muscle sarcoplasmic reticulum Ca2+-ATPase.

Loukianov E, Ji Y, Grupp IL, Kirkpatrick DL, Baker DL, Loukianova T, Grupp G, Lytton J, Walsh RA, Periasamy M.

Circ Res. 1998 Nov 2;83(9):889-97.

PMID:
9797337
48.

Upregulation of atrial natriuretic peptide gene expression in remnant kidney of rats with reduced renal mass.

Totsune K, Mackenzie HS, Totsune H, Troy JL, Lytton J, Brenner BM.

J Am Soc Nephrol. 1998 Sep;9(9):1613-9.

49.

Molecular cloning of a novel potassium-dependent sodium-calcium exchanger from rat brain.

Tsoi M, Rhee KH, Bungard D, Li XF, Lee SL, Auer RN, Lytton J.

J Biol Chem. 1998 Feb 13;273(7):4155-62.

50.

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