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Items: 16


On the diverse and opposing effects of nutrition on pathogen virulence.

Pike VL, Lythgoe KA, King KC.

Proc Biol Sci. 2019 Jul 10;286(1906):20191220. doi: 10.1098/rspb.2019.1220. Epub 2019 Jul 10.


Link between the numbers of particles and variants founding new HIV-1 infections depends on the timing of transmission.

Thompson RN, Wymant C, Spriggs RA, Raghwani J, Fraser C, Lythgoe KA.

Virus Evol. 2019 Jan 30;5(1):vey038. doi: 10.1093/ve/vey038. eCollection 2019 Jan.


High-Resolution Evolutionary Analysis of Within-Host Hepatitis C Virus Infection.

Raghwani J, Wu CH, Ho CKY, De Jong M, Molenkamp R, Schinkel J, Pybus OG, Lythgoe KA.

J Infect Dis. 2019 May 5;219(11):1722-1729. doi: 10.1093/infdis/jiy747.


Structure-Guided Identification of a Nonhuman Morbillivirus with Zoonotic Potential.

Abdullah N, Kelly JT, Graham SC, Birch J, Gonçalves-Carneiro D, Mitchell T, Thompson RN, Lythgoe KA, Logan N, Hosie MJ, Bavro VN, Willett BJ, Heaton MP, Bailey D.

J Virol. 2018 Nov 12;92(23). pii: e01248-18. doi: 10.1128/JVI.01248-18. Print 2018 Dec 1.


Hepatitis B Virus Adaptation to the CD8+ T Cell Response: Consequences for Host and Pathogen.

Lumley SF, McNaughton AL, Klenerman P, Lythgoe KA, Matthews PC.

Front Immunol. 2018 Jul 16;9:1561. doi: 10.3389/fimmu.2018.01561. eCollection 2018. Review.


Evolution of HIV-1 within untreated individuals and at the population scale in Uganda.

Raghwani J, Redd AD, Longosz AF, Wu CH, Serwadda D, Martens C, Kagaayi J, Sewankambo N, Porcella SF, Grabowski MK, Quinn TC, Eller MA, Eller LA, Wabwire-Mangen F, Robb ML, Fraser C, Lythgoe KA.

PLoS Pathog. 2018 Jul 27;14(7):e1007167. doi: 10.1371/journal.ppat.1007167. eCollection 2018 Jul.


Short-Sighted Virus Evolution and a Germline Hypothesis for Chronic Viral Infections.

Lythgoe KA, Gardner A, Pybus OG, Grove J.

Trends Microbiol. 2017 May;25(5):336-348. doi: 10.1016/j.tim.2017.03.003. Epub 2017 Apr 1. Review.


Effect of the Latent Reservoir on the Evolution of HIV at the Within- and Between-Host Levels.

Doekes HM, Fraser C, Lythgoe KA.

PLoS Comput Biol. 2017 Jan 19;13(1):e1005228. doi: 10.1371/journal.pcbi.1005228. eCollection 2017 Jan.


A transmission-virulence evolutionary trade-off explains attenuation of HIV-1 in Uganda.

Blanquart F, Grabowski MK, Herbeck J, Nalugoda F, Serwadda D, Eller MA, Robb ML, Gray R, Kigozi G, Laeyendecker O, Lythgoe KA, Nakigozi G, Quinn TC, Reynolds SJ, Wawer MJ, Fraser C.

Elife. 2016 Nov 5;5. pii: e20492. doi: 10.7554/eLife.20492.


Large Variations in HIV-1 Viral Load Explained by Shifting-Mosaic Metapopulation Dynamics.

Lythgoe KA, Blanquart F, Pellis L, Fraser C.

PLoS Biol. 2016 Oct 5;14(10):e1002567. doi: 10.1371/journal.pbio.1002567. eCollection 2016 Oct.


Is HIV short-sighted? Insights from a multistrain nested model.

Lythgoe KA, Pellis L, Fraser C.

Evolution. 2013 Oct;67(10):2769-82. doi: 10.1111/evo.12166. Epub 2013 Jun 13.


New insights into the evolutionary rate of HIV-1 at the within-host and epidemiological levels.

Lythgoe KA, Fraser C.

Proc Biol Sci. 2012 Aug 22;279(1741):3367-75. doi: 10.1098/rspb.2012.0595. Epub 2012 May 16.


Effects of acquired immunity and mating strategy on the genetic structure of parasite populations.

Lythgoe KA.

Am Nat. 2002 May;159(5):519-29. doi: 10.1086/339462.


Parasite-intrinsic factors can explain ordered progression of trypanosome antigenic variation.

Lythgoe KA, Morrison LJ, Read AF, Barry JD.

Proc Natl Acad Sci U S A. 2007 May 8;104(19):8095-100. Epub 2007 Apr 26.


Catching the Red Queen? The advice of the Rose.

Lythgoe KA, Read AF.

Trends Ecol Evol. 1998 Dec 1;13(12):473-4. No abstract available.


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