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Preventing injuries must be a priority to prevent disease in the twenty-first century.

Dorney K, Dodington JM, Rees CA, Farrell CA, Hanson HR, Lyons TW, Lee LK; and the Injury Free Coalition for Kids®.

Pediatr Res. 2019 Aug 29. doi: 10.1038/s41390-019-0549-7. [Epub ahead of print] Review.


Racial and Ethnic Differences in Emergency Department Utilization and Diagnosis for Sports-Related Head Injuries.

Lyons TW, Miller KA, Miller AF, Mannix R.

Front Neurol. 2019 Jul 2;10:690. doi: 10.3389/fneur.2019.00690. eCollection 2019.


Association of Herpes Simplex Virus Testing with Hospital Length of Stay for Infants ≤60 Days of Age Undergoing Evaluation for Meningitis.

Aronson PL, Cruz AT, Freedman SB, Balamuth F, Grether-Jones KL, Lyons TW, Fleming AH, Louie J, Mistry RD, Garro AC, Shah SS, Nigrovic LE; Pediatric Emergency Medicine Clinical Research Network (PEM CRC) Herpes Simplex Virus (HSV) Study Group.

J Hosp Med. 2019 Aug 1;14(8):492-495. doi: 10.12788/jhm.3202. Epub 2019 May 12.


Carbonate formation in salt dome cap rocks by microbial anaerobic oxidation of methane.

Caesar KH, Kyle JR, Lyons TW, Tripati A, Loyd SJ.

Nat Commun. 2019 Feb 18;10(1):808. doi: 10.1038/s41467-019-08687-z.


Case 1: A Medically Complex 10-month-old Boy with Lethargy.

Toce MS, Lyons TW.

Pediatr Rev. 2019 Feb;40(2):79-81. doi: 10.1542/pir.2017-0190. No abstract available.


Absence of biomarker evidence for early eukaryotic life from the Mesoproterozoic Roper Group: Searching across a marine redox gradient in mid-Proterozoic habitability.

Nguyen K, Love GD, Zumberge JA, Kelly AE, Owens JD, Rohrssen MK, Bates SM, Cai C, Lyons TW.

Geobiology. 2019 May;17(3):247-260. doi: 10.1111/gbi.12329. Epub 2019 Jan 10.


Risk of Serious Infections Associated with Biologic Agents in Juvenile Idiopathic Arthritis: A Systematic Review and Meta-Analyses.

Aeschlimann FA, Chong SL, Lyons TW, Beinvogl BC, Góez-Mogollón LM, Tan S, Laxer RM.

J Pediatr. 2019 Jan;204:162-171.e3. doi: 10.1016/j.jpeds.2018.08.065. Epub 2018 Oct 11.


Nitrous oxide from chemodenitrification: A possible missing link in the Proterozoic greenhouse and the evolution of aerobic respiration.

Stanton CL, Reinhard CT, Kasting JF, Ostrom NE, Haslun JA, Lyons TW, Glass JB.

Geobiology. 2018 Nov;16(6):597-609. doi: 10.1111/gbi.12311. Epub 2018 Aug 22.


Thallium isotopes reveal protracted anoxia during the Toarcian (Early Jurassic) associated with volcanism, carbon burial, and mass extinction.

Them TR 2nd, Gill BC, Caruthers AH, Gerhardt AM, Gröcke DR, Lyons TW, Marroquín SM, Nielsen SG, Trabucho Alexandre JP, Owens JD.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6596-6601. doi: 10.1073/pnas.1803478115. Epub 2018 Jun 11.


Tracking the rise of eukaryotes to ecological dominance with zinc isotopes.

Isson TT, Love GD, Dupont CL, Reinhard CT, Zumberge AJ, Asael D, Gueguen B, McCrow J, Gill BC, Owens J, Rainbird RH, Rooney AD, Zhao MY, Stueeken EE, Konhauser KO, John SG, Lyons TW, Planavsky NJ.

Geobiology. 2018 Jul;16(4):341-352. doi: 10.1111/gbi.12289. Epub 2018 Jun 5.


Use of a National Database to Assess Pediatric Emergency Care Across United States Emergency Departments.

Michelson KA, Lyons TW, Hudgins JD, Levy JA, Monuteaux MC, Finkelstein JA, Bachur RG.

Acad Emerg Med. 2018 Dec;25(12):1355-1364. doi: 10.1111/acem.13489. Epub 2018 Jul 4.


Late inception of a resiliently oxygenated upper ocean.

Lu W, Ridgwell A, Thomas E, Hardisty DS, Luo G, Algeo TJ, Saltzman MR, Gill BC, Shen Y, Ling HF, Edwards CT, Whalen MT, Zhou X, Gutchess KM, Jin L, Rickaby REM, Jenkyns HC, Lyons TW, Lenton TM, Kump LR, Lu Z.

Science. 2018 Jul 13;361(6398):174-177. doi: 10.1126/science.aar5372. Epub 2018 May 31.


Accuracy of Herpes Simplex Virus Polymerase Chain Reaction Testing of the Blood for Central Nervous System Herpes Simplex Virus Infections in Infants.

Lyons TW, Cruz AT, Freedman SB, Nigrovic LE; Herpes Simplex Virus Study Group of the Pediatric Emergency Medicine Collaborative Research Committee (PEMCRC).

J Pediatr. 2018 Sep;200:274-276.e1. doi: 10.1016/j.jpeds.2018.04.061. Epub 2018 May 18.


Exoplanet Biosignatures: Understanding Oxygen as a Biosignature in the Context of Its Environment.

Meadows VS, Reinhard CT, Arney GN, Parenteau MN, Schwieterman EW, Domagal-Goldman SD, Lincowski AP, Stapelfeldt KR, Rauer H, DasSarma S, Hegde S, Narita N, Deitrick R, Lustig-Yaeger J, Lyons TW, Siegler N, Grenfell JL.

Astrobiology. 2018 Jun;18(6):630-662. doi: 10.1089/ast.2017.1727. Epub 2018 May 10. Review.


Exoplanet Biosignatures: A Review of Remotely Detectable Signs of Life.

Schwieterman EW, Kiang NY, Parenteau MN, Harman CE, DasSarma S, Fisher TM, Arney GN, Hartnett HE, Reinhard CT, Olson SL, Meadows VS, Cockell CS, Walker SI, Grenfell JL, Hegde S, Rugheimer S, Hu R, Lyons TW.

Astrobiology. 2018 Jun;18(6):663-708. doi: 10.1089/ast.2017.1729. Epub 2018 May 4. Review.


Timing and Location of Emergency Department Revisits.

Michelson KA, Lyons TW, Bachur RG, Monuteaux MC, Finkelstein JA.

Pediatrics. 2018 May;141(5). pii: e20174087. doi: 10.1542/peds.2017-4087. Epub 2018 Apr 12.


What the ~1.4 Ga Xiamaling Formation can and cannot tell us about the mid-Proterozoic ocean.

Diamond CW, Planavsky NJ, Wang C, Lyons TW.

Geobiology. 2018 May;16(3):219-236. doi: 10.1111/gbi.12282. Epub 2018 Mar 25.


A Next Generation Synthesis of BACE1 Inhibitor Verubecestat (MK-8931).

Thaisrivongs DA, Morris WJ, Tan L, Song ZJ, Lyons TW, Waldman JH, Naber JR, Chen W, Chen L, Zhang B, Yang J.

Org Lett. 2018 Mar 16;20(6):1568-1571. doi: 10.1021/acs.orglett.8b00259. Epub 2018 Feb 26.


Reactive Oxygen Species: Radical Factors in the Evolution of Animal Life: A molecular timescale from Earth's earliest history to the rise of complex life.

Taverne YJ, Merkus D, Bogers AJ, Halliwell B, Duncker DJ, Lyons TW.

Bioessays. 2018 Mar;40(3). doi: 10.1002/bies.201700158. Epub 2018 Feb 7. Review.


Trends in Severe Pediatric Emergency Conditions in a National Cohort, 2008 to 2014.

Michelson KA, Hudgins JD, Burke LG, Lyons TW, Monuteaux MC, Bachur RG, Finkelstein JA.

Pediatr Emerg Care. 2018 Jan 16. doi: 10.1097/PEC.0000000000001409. [Epub ahead of print]


Herpes Simplex Virus Infection in Infants Undergoing Meningitis Evaluation.

Cruz AT, Freedman SB, Kulik DM, Okada PJ, Fleming AH, Mistry RD, Thomson JE, Schnadower D, Arms JL, Mahajan P, Garro AC, Pruitt CM, Balamuth F, Uspal NG, Aronson PL, Lyons TW, Thompson AD, Curtis SJ, Ishimine PT, Schmidt SM, Bradin SA, Grether-Jones KL, Miller AS, Louie J, Shah SS, Nigrovic LE; HSV Study Group of the Pediatric Emergency Medicine Collaborative Research Committee.

Pediatrics. 2018 Feb;141(2). pii: e20171688. doi: 10.1542/peds.2017-1688. Epub 2018 Jan 3.


A Systematic Review and Meta-Analysis of the Management and Outcomes of Isolated Skull Fractures in Children.

Bressan S, Marchetto L, Lyons TW, Monuteaux MC, Freedman SB, Da Dalt L, Nigrovic LE.

Ann Emerg Med. 2018 Jun;71(6):714-724.e2. doi: 10.1016/j.annemergmed.2017.10.014. Epub 2017 Nov 24.


The oceanic budgets of nickel and zinc isotopes: the importance of sulfidic environments as illustrated by the Black Sea.

Vance D, Little SH, Archer C, Cameron V, Andersen MB, Rijkenberg MJA, Lyons TW.

Philos Trans A Math Phys Eng Sci. 2016 Nov 28;374(2081). pii: 20150294. doi: 10.1098/rsta.2015.0294.


Patients Visiting Multiple Emergency Departments: Patterns, Costs, and Risk Factors.

Lyons TW, Olson KL, Palmer NP, Horwitz R, Mandl KD, Fine AM.

Acad Emerg Med. 2017 Nov;24(11):1349-1357. doi: 10.1111/acem.13304. Epub 2017 Oct 23.


Environmental niches and metabolic diversity in Neoarchean lakes.

Stüeken EE, Buick R, Anderson RE, Baross JA, Planavsky NJ, Lyons TW.

Geobiology. 2017 Nov;15(6):767-783. doi: 10.1111/gbi.12251. Epub 2017 Aug 30.


Impact of Enteroviral Polymerase Chain Reaction Testing on Length of Stay for Infants 60 Days Old or Younger.

Aronson PL, Lyons TW, Cruz AT, Freedman SB, Okada PJ, Fleming AH, Arms JL, Thompson AD, Schmidt SM, Louie J, Alfonzo MJ, Monuteaux MC, Nigrovic LE; Pediatric Emergency Medicine Clinical Research Network (PEM CRC) Herpes Simplex Virus (HSV) Study Group.

J Pediatr. 2017 Oct;189:169-174.e2. doi: 10.1016/j.jpeds.2017.06.021. Epub 2017 Jul 10.


Utility of Lumbar Puncture in Children Presenting With Status Epilepticus.

Michelson KA, Lyons TW, Johnson KB, Nigrovic LE, Harper MB, Kimia AA.

Pediatr Emerg Care. 2017 Aug;33(8):544-547. doi: 10.1097/PEC.0000000000001225.


Correction of Cerebrospinal Fluid Protein in Infants With Traumatic Lumbar Punctures.

Lyons TW, Cruz AT, Freedman SB, Arms JL, Aronson PL, Fleming AH, Kulik DM, Mahajan P, Mistry RD, Pruitt CM, Thompson AD, Nigrovic LE; Herpes Simplex Virus Study Group of the Pediatric Emergency Medicine Collaborative Research Committee (PEM CRC).

Pediatr Infect Dis J. 2017 Oct;36(10):1006-1008. doi: 10.1097/INF.0000000000001634.


False Negatives for Remote Life Detection on Ocean-Bearing Planets: Lessons from the Early Earth.

Reinhard CT, Olson SL, Schwieterman EW, Lyons TW.

Astrobiology. 2017 Apr;17(4):287-297. doi: 10.1089/ast.2016.1598.


Paleoecology and paleoceanography of the Athel silicilyte, Ediacaran-Cambrian boundary, Sultanate of Oman.

Stolper DA, Love GD, Bates S, Lyons TW, Young E, Sessions AL, Grotzinger JP.

Geobiology. 2017 May;15(3):401-426. doi: 10.1111/gbi.12236. Epub 2017 Apr 7.


Interpretation of Cerebrospinal Fluid White Blood Cell Counts in Young Infants With a Traumatic Lumbar Puncture.

Lyons TW, Cruz AT, Freedman SB, Neuman MI, Balamuth F, Mistry RD, Mahajan P, Aronson PL, Thomson JE, Pruitt CM, Shah SS, Nigrovic LE; Pediatric Emergency Medicine Clinical Research Network (PEM CRC) Herpes Simplex Virus Study Group.

Ann Emerg Med. 2017 May;69(5):622-631. doi: 10.1016/j.annemergmed.2016.10.008. Epub 2016 Dec 29.


Evolution of the global phosphorus cycle.

Reinhard CT, Planavsky NJ, Gill BC, Ozaki K, Robbins LJ, Lyons TW, Fischer WW, Wang C, Cole DB, Konhauser KO.

Nature. 2017 Jan 19;541(7637):386-389. doi: 10.1038/nature20772. Epub 2016 Dec 21.


Uncovering the spatial heterogeneity of Ediacaran carbon cycling.

Li C, Hardisty DS, Luo G, Huang J, Algeo TJ, Cheng M, Shi W, An Z, Tong J, Xie S, Jiao N, Lyons TW.

Geobiology. 2017 Mar;15(2):211-224. doi: 10.1111/gbi.12222. Epub 2016 Dec 20.


Cyanobacterial Diazotrophy and Earth's Delayed Oxygenation.

Olson SL, Reinhard CT, Lyons TW.

Front Microbiol. 2016 Sep 23;7:1526. eCollection 2016.


Limited role for methane in the mid-Proterozoic greenhouse.

Olson SL, Reinhard CT, Lyons TW.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11447-11452. Epub 2016 Sep 26.


Earth's oxygen cycle and the evolution of animal life.

Reinhard CT, Planavsky NJ, Olson SL, Lyons TW, Erwin DH.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):8933-8. doi: 10.1073/pnas.1521544113. Epub 2016 Jul 25.


A QI Initiative to Reduce Hospitalization for Children With Isolated Skull Fractures.

Lyons TW, Stack AM, Monuteaux MC, Parver SL, Gordon CR, Gordon CD, Proctor MR, Nigrovic LE.

Pediatrics. 2016 Jun;137(6). pii: e20153370. doi: 10.1542/peds.2015-3370. Epub 2016 May 11.


Carbon and Sulfur Cycling below the Chemocline in a Meromictic Lake and the Identification of a Novel Taxonomic Lineage in the FCB Superphylum, Candidatus Aegiribacteria.

Hamilton TL, Bovee RJ, Sattin SR, Mohr W, Gilhooly WP 3rd, Lyons TW, Pearson A, Macalady JL.

Front Microbiol. 2016 Apr 27;7:598. doi: 10.3389/fmicb.2016.00598. eCollection 2016.


No evidence for high atmospheric oxygen levels 1,400 million years ago.

Planavsky NJ, Cole DB, Reinhard CT, Diamond C, Love GD, Luo G, Zhang S, Konhauser KO, Lyons TW.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2550-1. doi: 10.1073/pnas.1601925113. Epub 2016 Apr 20. No abstract available.


Oceanic oxygenation events in the anoxic Ediacaran ocean.

Sahoo SK, Planavsky NJ, Jiang G, Kendall B, Owens JD, Wang X, Shi X, Anbar AD, Lyons TW.

Geobiology. 2016 Sep;14(5):457-68. doi: 10.1111/gbi.12182. Epub 2016 Mar 30.


Yield of emergent neuroimaging in children with new-onset seizure and status epilepticus.

Lyons TW, Johnson KB, Michelson KA, Nigrovic LE, Loddenkemper T, Prabhu SP, Kimia AA.

Seizure. 2016 Feb;35:4-10. doi: 10.1016/j.seizure.2015.12.009. Epub 2015 Dec 25.


Transient episodes of mild environmental oxygenation and oxidative continental weathering during the late Archean.

Kendall B, Creaser RA, Reinhard CT, Lyons TW, Anbar AD.

Sci Adv. 2015 Nov 20;1(10):e1500777. doi: 10.1126/sciadv.1500777. eCollection 2015 Nov.


Quality Improvement Effort to Reduce Cranial CTs for Children With Minor Blunt Head Trauma.

Nigrovic LE, Stack AM, Mannix RC, Lyons TW, Samnaliev M, Bachur RG, Proctor MR.

Pediatrics. 2015 Jul;136(1):e227-33. doi: 10.1542/peds.2014-3588.


Earth history. Low mid-Proterozoic atmospheric oxygen levels and the delayed rise of animals.

Planavsky NJ, Reinhard CT, Wang X, Thomson D, McGoldrick P, Rainbird RH, Johnson T, Fischer WW, Lyons TW.

Science. 2014 Oct 31;346(6209):635-8. doi: 10.1126/science.1258410.


Deep-water microbialites of the Mesoproterozoic Dismal Lakes Group: microbial growth, lithification, and implications for coniform stromatolites.

Bartley JK, Kah LC, Frank TD, Lyons TW.

Geobiology. 2015 Jan;13(1):15-32. doi: 10.1111/gbi.12114. Epub 2014 Oct 29.


Coupled reductive and oxidative sulfur cycling in the phototrophic plate of a meromictic lake.

Hamilton TL, Bovee RJ, Thiel V, Sattin SR, Mohr W, Schaperdoth I, Vogl K, Gilhooly WP 3rd, Lyons TW, Tomsho LP, Schuster SC, Overmann J, Bryant DA, Pearson A, Macalady JL.

Geobiology. 2014 Sep;12(5):451-68. doi: 10.1111/gbi.12092. Epub 2014 Jun 28.


Pediatric status epilepticus: how common is cerebrospinal fluid pleocytosis in the absence of infection?

Johnson KB, Michelson KA, Lyons TW, Nigrovic LE, Landschaft A, Loddenkemper T, Kimia AA.

Seizure. 2014 Aug;23(7):573-5. doi: 10.1016/j.seizure.2014.03.015. Epub 2014 Apr 26.


Evolution: a fixed-nitrogen fix in the early ocean?

Lyons TW, Reinhard CT, Planavsky NJ.

Curr Biol. 2014 Mar 31;24(7):R276-8. doi: 10.1016/j.cub.2014.02.034.


The rise of oxygen in Earth's early ocean and atmosphere.

Lyons TW, Reinhard CT, Planavsky NJ.

Nature. 2014 Feb 20;506(7488):307-15. doi: 10.1038/nature13068. Review.


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