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Nicotinamide for skin cancer chemoprevention: effects of nicotinamide on melanoma in vitro and in vivo.

Malesu R, Martin AJ, Lyons JG, Scolyer RA, Chen AC, McKenzie CA, Madore J, Halliday GM, Damian DL.

Photochem Photobiol Sci. 2020 Jan 16. doi: 10.1039/c9pp00388f. [Epub ahead of print]


Peripheral (not central) corneal epithelia contribute to the closure of an annular debridement injury.

Park M, Richardson A, Pandzic E, Lobo EP, Lyons JG, Di Girolamo N.

Proc Natl Acad Sci U S A. 2019 Dec 16. pii: 201912260. doi: 10.1073/pnas.1912260116. [Epub ahead of print]


Understanding utilization patterns of biologics and biosimilars in the United States to support postmarketing studies of safety and effectiveness.

Dutcher SK, Fazio-Eynullayeva E, Eworuke E, Carruth A, Dee EC, Blum MD, Nguyen MD, Toh S, Panozzo CA, Lyons JG.

Pharmacoepidemiol Drug Saf. 2019 Dec 11. doi: 10.1002/pds.4908. [Epub ahead of print]


Additive Manufacturing of Personalized Pharmaceutical Dosage Forms via Stereolithography.

Healy AV, Fuenmayor E, Doran P, Geever LM, Higginbotham CL, Lyons JG.

Pharmaceutics. 2019 Dec 3;11(12). pii: E645. doi: 10.3390/pharmaceutics11120645.


Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4.

Wang Z, Wu VH, Allevato MM, Gilardi M, He Y, Luis Callejas-Valera J, Vitale-Cross L, Martin D, Amornphimoltham P, Mcdermott J, Yung BS, Goto Y, Molinolo AA, Sharabi AB, Cohen EEW, Chen Q, Lyons JG, Alexandrov LB, Gutkind JS.

Nat Commun. 2019 Dec 5;10(1):5546. doi: 10.1038/s41467-019-13471-0.


Mass-customization of oral tablets via the combination of 3D printing and injection molding.

Fuenmayor E, O'Donnell C, Gately N, Doran P, Devine DM, Lyons JG, McConville C, Major I.

Int J Pharm. 2019 Oct 5;569:118611. doi: 10.1016/j.ijpharm.2019.118611. Epub 2019 Aug 12.


Medical record-based ascertainment of behaviors suggestive of opioid misuse, diversion, abuse, and/or addiction among individuals showing evidence of doctor/pharmacy shopping.

Esposito DB, Cepeda MS, Lyons JG, Yin R, Lanes S; Members of the Opioid Post-Marketing Consortium Observational Studies Working Group.

J Pain Res. 2019 Jul 24;12:2291-2303. doi: 10.2147/JPR.S203350. eCollection 2019.


Influence of Annealing and Biaxial Expansion on the Properties of Poly(l-Lactic Acid) Medical Tubing.

Dillon B, Doran P, Fuenmayor E, Healy AV, Gately NM, Major I, Lyons JG.

Polymers (Basel). 2019 Jul 11;11(7). pii: E1172. doi: 10.3390/polym11071172.


Faster Release of Lumen-Loaded Drugs than Matrix-Loaded Equivalent in Polylactic Acid/Halloysite Nanotubes.

Venkatesh C, Clear O, Major I, Lyons JG, Devine DM.

Materials (Basel). 2019 Jun 5;12(11). pii: E1830. doi: 10.3390/ma12111830.


Development of predictive models to identify advanced-stage cancer patients in a US healthcare claims database.

Esposito DB, Russo L, Oksen D, Yin R, Desai VCA, Lyons JG, Verpillat P, Peñalvo JL, Lamy FX, Lanes S.

Cancer Epidemiol. 2019 Aug;61:30-37. doi: 10.1016/j.canep.2019.05.006. Epub 2019 May 22.


Micro-Injection Moulding of Poly(vinylpyrrolidone-vinyl acetate) Binary and Ternary Amorphous Solid Dispersions.

Pezzoli R, Hopkins Jnr M, Direur G, Gately N, Lyons JG, Higginbotham CL.

Pharmaceutics. 2019 May 18;11(5). pii: E240. doi: 10.3390/pharmaceutics11050240.


The Influence of Low Shear Microbore Extrusion on the Properties of High Molecular Weight Poly(l-Lactic Acid) for Medical Tubing Applications.

Dillon B, Doran P, Fuenmayor E, Healy AV, Gately NM, Major I, Lyons JG.

Polymers (Basel). 2019 Apr 18;11(4). pii: E710. doi: 10.3390/polym11040710.


Comparison of fused-filament fabrication to direct compression and injection molding in the manufacture of oral tablets.

Fuenmayor E, Forde M, Healy AV, Devine DM, Lyons JG, McConville C, Major I.

Int J Pharm. 2019 Mar 10;558:328-340. doi: 10.1016/j.ijpharm.2019.01.013. Epub 2019 Jan 16.


Visualizing the Contribution of Keratin-14+ Limbal Epithelial Precursors in Corneal Wound Healing.

Park M, Richardson A, Pandzic E, Lobo EP, Whan R, Watson SL, Lyons JG, Wakefield D, Di Girolamo N.

Stem Cell Reports. 2019 Jan 8;12(1):14-28. doi: 10.1016/j.stemcr.2018.11.014. Epub 2018 Dec 13.


Brahma deficiency in keratinocytes promotes UV carcinogenesis by accelerating the escape from cell cycle arrest and the formation of DNA photolesions.

Farrell AW, Halliday GM, Lyons JG.

J Dermatol Sci. 2018 Dec;92(3):254-263. doi: 10.1016/j.jdermsci.2018.11.006. Epub 2018 Nov 22.


A Reduction in Inflammatory Macrophages May Contribute to Skin Cancer Chemoprevention by Nicotinamide.

Minocha R, Martin AJ, Chen AC, Scolyer RA, Lyons JG, McKenzie CA, Madore J, Halliday GM, Damian DL.

J Invest Dermatol. 2019 Feb;139(2):467-469. doi: 10.1016/j.jid.2018.08.018. Epub 2018 Sep 20. No abstract available.


Investigation of miscibility estimation methods between indomethacin and poly(vinylpyrrolidone-co-vinyl acetate).

Pezzoli R, Lyons JG, Gately N, Higginbotham CL.

Int J Pharm. 2018 Oct 5;549(1-2):50-57. doi: 10.1016/j.ijpharm.2018.07.039. Epub 2018 Jul 26.


Assembly and activation of the Hippo signalome by FAT1 tumor suppressor.

Martin D, Degese MS, Vitale-Cross L, Iglesias-Bartolome R, Valera JLC, Wang Z, Feng X, Yeerna H, Vadmal V, Moroishi T, Thorne RF, Zaida M, Siegele B, Cheong SC, Molinolo AA, Samuels Y, Tamayo P, Guan KL, Lippman SM, Lyons JG, Gutkind JS.

Nat Commun. 2018 Jul 9;9(1):2372. doi: 10.1038/s41467-018-04590-1.


Human papillomavirus 16 E6 modulates the expression of miR-496 in oropharyngeal cancer.

Mason D, Zhang X, Marques TM, Rose B, Khoury S, Hill M, Deutsch F, Lyons JG, Gama-Carvalho M, Tran N.

Virology. 2018 Aug;521:149-157. doi: 10.1016/j.virol.2018.05.022. Epub 2018 Jun 20.


Sensitization of prostate cancer to radiation therapy: Molecules and pathways to target.

Yao M, Rogers L, Suchowerska N, Choe D, Al-Dabbas MA, Narula RS, Lyons JG, Sved P, Li Z, Dong Q.

Radiother Oncol. 2018 Aug;128(2):283-300. doi: 10.1016/j.radonc.2018.05.021. Epub 2018 Jun 18. Review.


Material Considerations for Fused-Filament Fabrication of Solid Dosage Forms.

Fuenmayor E, Forde M, Healy AV, Devine DM, Lyons JG, McConville C, Major I.

Pharmaceutics. 2018 Apr 2;10(2). pii: E44. doi: 10.3390/pharmaceutics10020044.


Erratum: Higher glomerular filtration rate is related to insulin resistance but not to obesity in a predominantly obese non-diabetic cohort.

Naderpoor N, Lyons JG, Mousa A, Ranasinha S, de Courten MPJ, Soldatos G, de Courten B.

Sci Rep. 2018 Mar 19;8:46962. doi: 10.1038/srep46962.


Challenges and recommendations for minimally resourced biobanks in tertiary Australian hospitals.

Chia N, Wen L, Lyons JG, Elliott M, Lee M, Palme CE, Clark JR, Gupta R.

ANZ J Surg. 2018 Jan;88(1-2):115-116. doi: 10.1111/ans.13909. No abstract available.


Patient and prescriber characteristics among patients with type 2 diabetes mellitus continuing or discontinuing sulfonylureas following insulin initiation: data from a large commercial database.

Beachler DC, Fernandes G, Deshpande G, Jemison J, Lyons JG, Lanes S, Liu J, McNeill A.

Curr Med Res Opin. 2018 Jun;34(6):1061-1069. doi: 10.1080/03007995.2017.1416348. Epub 2018 Jan 5.


Bone Loss at the Hip and Subsequent Mortality in Older Men: The Osteoporotic Fractures in Men (MrOS) Study.

Cawthon PM, Patel S, Ewing SK, Lui LY, Cauley JA, Lyons JG, Fredman L, Kado DM, Hoffman AR, Lane NE, Ensrud KE, Cummings SR, Orwoll ES; Osteoporotic Fractures in Men (MrOS) Study Research Group.

JBMR Plus. 2017 Aug;1(1):31-35. doi: 10.1002/jbm4.10006. Epub 2017 Jul 10.


Keratin-14-Positive Precursor Cells Spawn a Population of Migratory Corneal Epithelia that Maintain Tissue Mass throughout Life.

Richardson A, Lobo EP, Delic NC, Myerscough MR, Lyons JG, Wakefield D, Di Girolamo N.

Stem Cell Reports. 2017 Oct 10;9(4):1081-1096. doi: 10.1016/j.stemcr.2017.08.015. Epub 2017 Sep 21.


Synthesis, characterisation and phase transition behaviour of temperature-responsive physically crosslinked poly (N-vinylcaprolactam) based polymers for biomedical applications.

Halligan SC, Dalton MB, Murray KA, Dong Y, Wang W, Lyons JG, Geever LM.

Mater Sci Eng C Mater Biol Appl. 2017 Oct 1;79:130-139. doi: 10.1016/j.msec.2017.03.241. Epub 2017 Mar 29.


Higher glomerular filtration rate is related to insulin resistance but not to obesity in a predominantly obese non-diabetic cohort.

Naderpoor N, Lyons JG, Mousa A, Ranasinha S, de Courten MPJ, Soldatos G, de Courten B.

Sci Rep. 2017 Apr 3;7:45522. doi: 10.1038/srep45522. Erratum in: Sci Rep. 2018 Mar 19;8:46962.


Damaging Effects of Ultraviolet Radiation on the Cornea.

Delic NC, Lyons JG, Di Girolamo N, Halliday GM.

Photochem Photobiol. 2017 Jul;93(4):920-929. doi: 10.1111/php.12686. Epub 2017 Feb 28. Review.


Slow Gait Speed and Risk of Long-Term Nursing Home Residence in Older Women, Adjusting for Competing Risk of Mortality: Results from the Study of Osteoporotic Fractures.

Lyons JG, Ensrud KE, Schousboe JT, McCulloch CE, Taylor BC, Heeren TC, Stuver SO, Fredman L.

J Am Geriatr Soc. 2016 Dec;64(12):2522-2527. doi: 10.1111/jgs.14346. Epub 2016 Nov 22.


Bioengineered human heparin with anticoagulant activity.

Lord MS, Cheng B, Tang F, Lyons JG, Rnjak-Kovacina J, Whitelock JM.

Metab Eng. 2016 Nov;38:105-114. doi: 10.1016/j.ymben.2016.07.006. Epub 2016 Jul 18.


Impact of Competing Risk of Mortality on Association of Weight Loss With Risk of Central Body Fractures in Older Men: A Prospective Cohort Study.

Ensrud KE, Harrison SL, Cauley JA, Langsetmo L, Schousboe JT, Kado DM, Gourlay ML, Lyons JG, Fredman L, Napoli N, Crandall CJ, Lewis CE, Orwoll ES, Stefanick ML, Cawthon PM; Osteoporotic Fractures in Men (MrOS) Research Group.

J Bone Miner Res. 2017 Mar;32(3):624-632. doi: 10.1002/jbmr.3020. Epub 2016 Nov 7.


Renewal of the Holocrine Meibomian Glands by Label-Retaining, Unipotent Epithelial Progenitors.

Parfitt GJ, Lewis PN, Young RD, Richardson A, Lyons JG, Di Girolamo N, Jester JV.

Stem Cell Reports. 2016 Sep 13;7(3):399-410. doi: 10.1016/j.stemcr.2016.07.010. Epub 2016 Aug 11.


Self-organized centripetal movement of corneal epithelium in the absence of external cues.

Lobo EP, Delic NC, Richardson A, Raviraj V, Halliday GM, Di Girolamo N, Myerscough MR, Lyons JG.

Nat Commun. 2016 Aug 8;7:12388. doi: 10.1038/ncomms12388.


α3 Integrin of Cell-Cell Contact Mediates Kidney Fibrosis by Integrin-Linked Kinase in Proximal Tubular E-Cadherin Deficient Mice.

Zheng G, Zhang J, Zhao H, Wang H, Pang M, Qiao X, Lee SR, Hsu TT, Tan TK, Lyons JG, Zhao Y, Tian X, Loebel DAF, Rubera I, Tauc M, Wang Y, Wang Y, Wang YM, Cao Q, Wang C, Lee VWS, Alexander SI, Tam PPL, Harris DCH.

Am J Pathol. 2016 Jul;186(7):1847-1860. doi: 10.1016/j.ajpath.2016.03.015. Epub 2016 May 13.


Relationships between p53 mutation, HPV status and outcome in oropharyngeal squamous cell carcinoma.

Hong A, Zhang X, Jones D, Veillard AS, Zhang M, Martin A, Lyons JG, Lee CS, Rose B.

Radiother Oncol. 2016 Feb;118(2):342-9. doi: 10.1016/j.radonc.2016.02.009. Epub 2016 Mar 4.


E6 viral protein ratio correlates with outcomes in human papillomavirus related oropharyngeal cancer.

Hong A, Zhang X, Jones D, Zhang M, Lee CS, Lyons JG, Veillard AS, Rose B.

Cancer Biol Ther. 2016;17(2):181-7. doi: 10.1080/15384047.2015.1108489. Epub 2015 Nov 17.


Bisphenol A and the risk of cardiometabolic disorders: a systematic review with meta-analysis of the epidemiological evidence.

Rancière F, Lyons JG, Loh VH, Botton J, Galloway T, Wang T, Shaw JE, Magliano DJ.

Environ Health. 2015 May 31;14:46. doi: 10.1186/s12940-015-0036-5. Review.


5-HT1A Receptor-Mediated Autoinhibition and the Control of Serotonergic Cell Firing.

Andrade R, Huereca D, Lyons JG, Andrade EM, McGregor KM.

ACS Chem Neurosci. 2015 Jul 15;6(7):1110-5. doi: 10.1021/acschemneuro.5b00034. Epub 2015 May 26. Review.


The Relationship Between Caregiving and Mortality After Accounting for Time-Varying Caregiver Status and Addressing the Healthy Caregiver Hypothesis.

Fredman L, Lyons JG, Cauley JA, Hochberg M, Applebaum KM.

J Gerontol A Biol Sci Med Sci. 2015 Sep;70(9):1163-8. doi: 10.1093/gerona/glv009. Epub 2015 Apr 15.


The Effect of Transitions in Caregiving Status and Intensity on Perceived Stress Among 992 Female Caregivers and Noncaregivers.

Lyons JG, Cauley JA, Fredman L.

J Gerontol A Biol Sci Med Sci. 2015 Aug;70(8):1018-23. doi: 10.1093/gerona/glv001. Epub 2015 Mar 20.


Assessing the agreement between 3-meter and 6-meter walk tests in 136 community-dwelling older adults.

Lyons JG, Heeren T, Stuver SO, Fredman L.

J Aging Health. 2015 Jun;27(4):594-605. doi: 10.1177/0898264314556987. Epub 2014 Nov 4.


The head and neck cancer cell oncogenome: a platform for the development of precision molecular therapies.

Martin D, Abba MC, Molinolo AA, Vitale-Cross L, Wang Z, Zaida M, Delic NC, Samuels Y, Lyons JG, Gutkind JS.

Oncotarget. 2014 Oct 15;5(19):8906-23.


Brm inhibits the proliferative response of keratinocytes and corneal epithelial cells to ultraviolet radiation-induced damage.

Hassan NM, Painter N, Howlett CR, Farrell AW, Di Girolamo N, Lyons JG, Halliday GM.

PLoS One. 2014 Sep 25;9(9):e107931. doi: 10.1371/journal.pone.0107931. eCollection 2014.


Lower levels of high-density lipoprotein cholesterol in urban Africans presenting with communicable versus non-communicable forms of heart disease: the 'Heart of Soweto' hospital registry study.

Lyons JG, Sliwa K, Carrington MJ, Raal F, Pretorius S, Thienemann F, Stewart S.

BMJ Open. 2014 Jul 14;4(7):e005069. doi: 10.1136/bmjopen-2014-005069.


Tracing the fate of limbal epithelial progenitor cells in the murine cornea.

Di Girolamo N, Bobba S, Raviraj V, Delic NC, Slapetova I, Nicovich PR, Halliday GM, Wakefield D, Whan R, Lyons JG.

Stem Cells. 2015 Jan;33(1):157-69. doi: 10.1002/stem.1769.


Evidence for low high-density lipoprotein cholesterol levels in Australian indigenous peoples: a systematic review.

Lyons JG, O'Dea K, Walker KZ.

BMC Public Health. 2014 Jun 2;14:545. doi: 10.1186/1471-2458-14-545. Review.


Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects.

Forbes JM, Sourris KC, de Courten MP, Dougherty SL, Chand V, Lyons JG, Bertovic D, Coughlan MT, Schlaich MP, Soldatos G, Cooper ME, Straznicky NE, Kingwell BA, de Courten B.

Amino Acids. 2014 Feb;46(2):321-6. doi: 10.1007/s00726-013-1542-9. Epub 2013 Jul 6.


Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure.

Sourris KC, Lyons JG, Dougherty SL, Chand V, Straznicky NE, Schlaich MP, Grima MT, Cooper ME, Kingwell BA, de Courten MP, Forbes JM, de Courten B.

Clin Chem Lab Med. 2014 Jan 1;52(1):129-38. doi: 10.1515/cclm-2012-0850.


Commentary: tuberculosis, diabetes and smoking: a burden greater than the sum of its parts.

Lyons JG, Stewart S.

Int J Epidemiol. 2013 Feb;42(1):230-2. doi: 10.1093/ije/dys217. No abstract available.


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