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Items: 11


Streptococcal superantigen-induced expansion of human tonsil T cells leads to altered T follicular helper cell phenotype, B cell death and reduced immunoglobulin release.

Davies FJ, Olme C, Lynskey NN, Turner CE, Sriskandan S.

Clin Exp Immunol. 2019 Jul;197(1):83-94. doi: 10.1111/cei.13282. Epub 2019 Mar 13.


Impact of contusion injury on intramuscular emm1 group a streptococcus infection and lymphatic spread.

Lamb LE, Siggins MK, Scudamore C, Macdonald W, Turner CE, Lynskey NN, Tan LKK, Sriskandan S.

Virulence. 2018;9(1):1074-1084. doi: 10.1080/21505594.2018.1482180.


Multi-functional mechanisms of immune evasion by the streptococcal complement inhibitor C5a peptidase.

Lynskey NN, Reglinski M, Calay D, Siggins MK, Mason JC, Botto M, Sriskandan S.

PLoS Pathog. 2017 Aug 14;13(8):e1006493. doi: 10.1371/journal.ppat.1006493. eCollection 2017 Aug.


Identification of commonly expressed exoproteins and proteolytic cleavage events by proteomic mining of clinically relevant UK isolates of Staphylococcus aureus.

Smith DS, Siggins MK, Gierula M, Pichon B, Turner CE, Lynskey NN, Mosavie M, Kearns AM, Edwards RJ, Sriskandan S.

Microb Genom. 2016 Feb 23;2(2):e000049. doi: 10.1099/mgen.0.000049. eCollection 2016 Feb.


Modification of the classical Lancefield assay of group A streptococcal killing to reduce inter-donor variation.

Reglinski M, Lynskey NN, Sriskandan S.

J Microbiol Methods. 2016 May;124:69-71. doi: 10.1016/j.mimet.2016.03.015. Epub 2016 Mar 24.


Development of a multicomponent vaccine for Streptococcus pyogenes based on the antigenic targets of IVIG.

Reglinski M, Lynskey NN, Choi YJ, Edwards RJ, Sriskandan S.

J Infect. 2016 Apr;72(4):450-9. doi: 10.1016/j.jinf.2016.02.002. Epub 2016 Feb 12.


Identification of the Streptococcus pyogenes surface antigens recognised by pooled human immunoglobulin.

Reglinski M, Gierula M, Lynskey NN, Edwards RJ, Sriskandan S.

Sci Rep. 2015 Oct 28;5:15825. doi: 10.1038/srep15825.


Rapid Lymphatic Dissemination of Encapsulated Group A Streptococci via Lymphatic Vessel Endothelial Receptor-1 Interaction.

Lynskey NN, Banerji S, Johnson LA, Holder KA, Reglinski M, Wing PA, Rigby D, Jackson DG, Sriskandan S.

PLoS Pathog. 2015 Sep 9;11(9):e1005137. doi: 10.1371/journal.ppat.1005137. eCollection 2015 Sep.


A truncation in the regulator RocA underlies heightened capsule expression in serotype M3 group A streptococci.

Lynskey NN, Turner CE, Heng LS, Sriskandan S.

Infect Immun. 2015 Apr;83(4):1732-3. doi: 10.1128/IAI.02892-14. No abstract available.


RocA truncation underpins hyper-encapsulation, carriage longevity and transmissibility of serotype M18 group A streptococci.

Lynskey NN, Goulding D, Gierula M, Turner CE, Dougan G, Edwards RJ, Sriskandan S.

PLoS Pathog. 2013;9(12):e1003842. doi: 10.1371/journal.ppat.1003842. Epub 2013 Dec 19.


New understandings in Streptococcus pyogenes.

Lynskey NN, Lawrenson RA, Sriskandan S.

Curr Opin Infect Dis. 2011 Jun;24(3):196-202. doi: 10.1097/QCO.0b013e3283458f7e. Review.


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