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Items: 1 to 50 of 341

1.

Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines.

Hassett KJ, Benenato KE, Jacquinet E, Lee A, Woods A, Yuzhakov O, Himansu S, Deterling J, Geilich BM, Ketova T, Mihai C, Lynn A, McFadyen I, Moore MJ, Senn JJ, Stanton MG, Almarsson Ö, Ciaramella G, Brito LA.

Mol Ther Nucleic Acids. 2019 Feb 7;15:1-11. doi: 10.1016/j.omtn.2019.01.013. [Epub ahead of print]

2.

Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial.

McCann ME, de Graaff JC, Dorris L, Disma N, Withington D, Bell G, Grobler A, Stargatt R, Hunt RW, Sheppard SJ, Marmor J, Giribaldi G, Bellinger DC, Hartmann PL, Hardy P, Frawley G, Izzo F, von Ungern Sternberg BS, Lynn A, Wilton N, Mueller M, Polaner DM, Absalom AR, Szmuk P, Morton N, Berde C, Soriano S, Davidson AJ; GAS Consortium.

Lancet. 2019 Feb 16;393(10172):664-677. doi: 10.1016/S0140-6736(18)32485-1. Epub 2019 Feb 14.

PMID:
30782342
3.

GCAC: galaxy workflow system for predictive model building for virtual screening.

Bharti DR, Hemrom AJ, Lynn AM.

BMC Bioinformatics. 2019 Feb 4;19(Suppl 13):550. doi: 10.1186/s12859-018-2492-8.

4.

Information theoretic measures and mutagenesis identify a novel linchpin residue involved in substrate selection within the nucleotide-binding domain of an ABCG family exporter Cdr1p.

Banerjee A, Vishwakarma P, Kumar A, Lynn AM, Prasad R.

Arch Biochem Biophys. 2019 Mar 15;663:143-150. doi: 10.1016/j.abb.2019.01.013. Epub 2019 Jan 14.

PMID:
30653962
5.

The E-helix is a central core in a conserved helical bundle involved in nucleotide binding and transmembrane domain intercalation in the ABC transporter superfamily.

Vishwakarma P, Banerjee A, Pasrija R, Prasad R, Lynn AM.

Int J Biol Macromol. 2019 Jan 9;127:95-106. doi: 10.1016/j.ijbiomac.2019.01.030. [Epub ahead of print]

PMID:
30639597
6.

Standardization of virtual-screening and post-processing protocols relevant to in-silico drug discovery.

Gupta S, Lynn AM, Gupta V.

3 Biotech. 2018 Dec;8(12):504. doi: 10.1007/s13205-018-1523-5. Epub 2018 Nov 30.

PMID:
30555765
7.

Corrigendum: Inflammation and Tissue Remodeling in the Bladder and Urethra in Feline Interstitial Cystitis.

Kullmann FA, McDonnell BM, Wolf-Johnston AS, Lynn AM, Giglio D, Getchell SE, Ruiz WG, Zabbarova IV, Ikeda Y, Kanai AJ, Roppolo JR, Bastacky SI, Apodaca G, Buffington CAT, Birder LA.

Front Syst Neurosci. 2018 Nov 8;12:58. doi: 10.3389/fnsys.2018.00058. eCollection 2018.

8.

Protein folding: Molecular dynamics simulations and in vitro studies for probing mechanism of urea- and guanidinium chloride-induced unfolding of horse cytochrome-c.

Khan SH, Prakash A, Pandey P, Lynn AM, Islam A, Hassan MI, Ahmad F.

Int J Biol Macromol. 2019 Feb 1;122:695-704. doi: 10.1016/j.ijbiomac.2018.10.186. Epub 2018 Oct 30.

PMID:
30389526
9.

Enrollment challenges in multicenter, international studies: The example of the GAS trial.

Gentry KR, Arnup SJ, Disma N, Dorris L, de Graaff JC, Hunyady A, Morton NS, Withington DE, McCann ME, Davidson AJ, Lynn AM; GAS Trial Consortium.

Paediatr Anaesth. 2019 Jan;29(1):51-58. doi: 10.1111/pan.13522. Epub 2018 Oct 29.

PMID:
30375133
10.

Phylogenetic and conservation analyses of MFS transporters.

Vishwakarma P, Banerjee A, Pasrija R, Prasad R, Lynn AM.

3 Biotech. 2018 Nov;8(11):462. doi: 10.1007/s13205-018-1476-8. Epub 2018 Oct 27.

PMID:
30370203
11.

Exploring the aggregation-prone regions from structural domains of human TDP-43.

Kumar V, Wahiduzzaman, Prakash A, Tomar AK, Srivastava A, Kundu B, Lynn AM, Imtaiyaz Hassan M.

Biochim Biophys Acta Proteins Proteom. 2019 Mar;1867(3):286-296. doi: 10.1016/j.bbapap.2018.10.008. Epub 2018 Oct 11.

PMID:
30315897
12.

Phylogenetic Analysis of the vesicular fusion SNARE machinery revealing its functional divergence across Eukaryotes.

Khurana GK, Vishwakarma P, Puri N, Lynn AM.

Bioinformation. 2018 Jul 31;14(7):361-368. doi: 10.6026/97320630014361. eCollection 2018.

13.

A multifaceted programme to reduce the rate of tongue-tie release surgery in newborn infants: Observational study.

Dixon B, Gray J, Elliot N, Shand B, Lynn A.

Int J Pediatr Otorhinolaryngol. 2018 Oct;113:156-163. doi: 10.1016/j.ijporl.2018.07.045. Epub 2018 Jul 27.

14.

ABC transportome inventory of human pathogenic yeast Candida glabrata: Phylogenetic and expression analysis.

Kumari S, Kumar M, Khandelwal NK, Kumari P, Varma M, Vishwakarma P, Shahi G, Sharma S, Lynn AM, Prasad R, Gaur NA.

PLoS One. 2018 Aug 28;13(8):e0202993. doi: 10.1371/journal.pone.0202993. eCollection 2018.

15.

A Randomized Controlled Trial of a Video-Enhanced Advanced Airway Curriculum for Pediatric Residents.

Miller KA, Monuteaux MC, Aftab S, Lynn A, Hillier D, Nagler J.

Acad Med. 2018 Dec;93(12):1858-1864. doi: 10.1097/ACM.0000000000002392.

PMID:
30095451
16.

Sensitivity of the C-Terminal Nuclease Domain of Kaposi's Sarcoma-Associated Herpesvirus ORF29 to Two Classes of Active-Site Ligands.

Miller JT, Zhao H, Masaoka T, Varnado B, Cornejo Castro EM, Marshall VA, Kouhestani K, Lynn AY, Aron KE, Xia A, Beutler JA, Hirsch DR, Tang L, Whitby D, Murelli RP, Le Grice SFJ.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e00233-18. doi: 10.1128/AAC.00233-18. Print 2018 Oct.

PMID:
30061278
17.

Involvement of TRPM4 in detrusor overactivity following spinal cord transection in mice.

Kullmann FA, Beckel JM, McDonnell B, Gauthier C, Lynn AM, Wolf-Johnston A, Kanai A, Zabbarova IV, Ikeda Y, de Groat WC, Birder LA.

Naunyn Schmiedebergs Arch Pharmacol. 2018 Nov;391(11):1191-1202. doi: 10.1007/s00210-018-1542-0. Epub 2018 Jul 27.

PMID:
30054681
18.

Insights into the DNA binding induced thermal stabilization of transcription factor FOXP3.

Prakash A, Kumar V, Lynn AM, Haque R.

J Biomol Struct Dyn. 2018 Nov 13:1-11. doi: 10.1080/07391102.2018.1486228. [Epub ahead of print]

PMID:
30047314
19.

Visits to Pediatric Clinics by Adult Patients: A Nationwide Survey in Taiwan.

Lee KL, Lynn AM, Chen TJ, Yang LY, Chiang SC.

Int J Environ Res Public Health. 2018 Jul 20;15(7). pii: E1538. doi: 10.3390/ijerph15071538.

20.

Inventory of ABC proteins and their putative role in salt and drug tolerance in Debaryomyces hansenii.

Wasi M, Khandelwal NK, Vishwakarma P, Lynn AM, Mondal AK, Prasad R.

Gene. 2018 Nov 15;676:227-242. doi: 10.1016/j.gene.2018.07.029. Epub 2018 Jul 17.

PMID:
30025928
21.

Illuminating the Black Box: The Real Risk of Serious Infection With Inflammatory Bowel Disease Therapies.

Lynn AM, Loftus EV Jr.

Gastroenterology. 2018 Aug;155(2):262-265. doi: 10.1053/j.gastro.2018.06.053. Epub 2018 Jul 5. No abstract available.

PMID:
29966613
22.

Safe and effective glycaemic control in premature infants: observational clinical results from the computerised STAR-GRYPHON protocol.

Knopp Nee Dickson JL, Lynn AM, Shaw GM, Chase JG.

Arch Dis Child Fetal Neonatal Ed. 2019 Mar;104(2):F205-F211. doi: 10.1136/archdischild-2017-314072. Epub 2018 Jun 21.

PMID:
29930148
23.

Effect of bilberry juice on indices of muscle damage and inflammation in runners completing a half-marathon: a randomised, placebo-controlled trial.

Lynn A, Garner S, Nelson N, Simper TN, Hall AC, Ranchordas MK.

J Int Soc Sports Nutr. 2018 May 2;15:22. doi: 10.1186/s12970-018-0227-x. eCollection 2018.

24.

Inflammation and Tissue Remodeling in the Bladder and Urethra in Feline Interstitial Cystitis.

Kullmann FA, McDonnell BM, Wolf-Johnston AS, Lynn AM, Giglio D, Getchell SE, Ruiz WG, Zabbarova IV, Ikeda Y, Kanai AJ, Roppolo JR, Bastacky SI, Apodaca G, Buffington CAT, Birder LA.

Front Syst Neurosci. 2018 Apr 13;12:13. doi: 10.3389/fnsys.2018.00013. eCollection 2018. Erratum in: Front Syst Neurosci. 2018 Nov 08;12:58.

25.

TFE-induced local unfolding and fibrillation of SOD1: bridging the experiment and simulation studies.

Kumar V, Prakash A, Pandey P, Lynn AM, Hassan MI.

Biochem J. 2018 May 18;475(10):1701-1719. doi: 10.1042/BCJ20180085.

PMID:
29686043
26.

A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates.

Sabnis S, Kumarasinghe ES, Salerno T, Mihai C, Ketova T, Senn JJ, Lynn A, Bulychev A, McFadyen I, Chan J, Almarsson Ö, Stanton MG, Benenato KE.

Mol Ther. 2018 Jun 6;26(6):1509-1519. doi: 10.1016/j.ymthe.2018.03.010. Epub 2018 Mar 14.

PMID:
29653760
27.

Surgical practice and outcome in 711 neonates and infants undergoing hernia repair in a large multicenter RCT: Secondary results from the GAS Study.

Disma N, Withington D, McCann ME, Hunt RW, Arnup SJ, Izzo F, de Graaff JC, Mattioli G, Morton N, Frawley G, Davidson A, Lynn A, Szmuk P, Thomas JJ, Ragg P, Pini Prato A; GAS Consortium.

J Pediatr Surg. 2018 Sep;53(9):1643-1650. doi: 10.1016/j.jpedsurg.2018.01.003. Epub 2018 Jan 31.

PMID:
29602555
28.

Effects of Caffeinated Gum on a Battery of Soccer-Specific Tests in Trained University-Standard Male Soccer Players.

Ranchordas MK, King G, Russell M, Lynn A, Russell M.

Int J Sport Nutr Exerc Metab. 2018 Nov 1;28(6):629-634. doi: 10.1123/ijsnem.2017-0405. Epub 2018 Sep 3.

PMID:
29584462
29.

Alterations in local stability and dynamics of A4V SOD1 in the presence of trifluoroethanol.

Kumar V, Prakash A, Lynn AM.

Biopolymers. 2018 Mar;109(3):e23102. doi: 10.1002/bip.23102. Epub 2018 Jan 25.

PMID:
29369331
30.

Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data.

Chaudhry A, Chung G, Lynn A, Yalvigi A, Brown C, Ellens H, O'Connor M, Lee C, Bentz J.

Drug Metab Dispos. 2018 Mar;46(3):279-290. doi: 10.1124/dmd.117.075606. Epub 2018 Jan 9.

PMID:
29317410
31.

Comparative analysis of thermal unfolding simulations of RNA recognition motifs (RRMs) of TAR DNA-binding protein 43 (TDP-43).

Prakash A, Kumar V, Meena NK, Hassan MI, Lynn AM.

J Biomol Struct Dyn. 2019 Jan;37(1):178-194. doi: 10.1080/07391102.2017.1422026. Epub 2018 Jan 10.

PMID:
29279008
32.

On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products.

Saar KL, Zhang Y, Müller T, Kumar CP, Devenish S, Lynn A, Łapińska U, Yang X, Linse S, Knowles TPJ.

Lab Chip. 2017 Dec 19;18(1):162-170. doi: 10.1039/c7lc00797c.

PMID:
29192926
33.

Safety Evaluation of Lipid Nanoparticle-Formulated Modified mRNA in the Sprague-Dawley Rat and Cynomolgus Monkey.

Sedic M, Senn JJ, Lynn A, Laska M, Smith M, Platz SJ, Bolen J, Hoge S, Bulychev A, Jacquinet E, Bartlett V, Smith PF.

Vet Pathol. 2018 Mar;55(2):341-354. doi: 10.1177/0300985817738095. Epub 2017 Nov 30.

PMID:
29191134
34.

Clinical trial designs and models for analgesic medications for acute pain in neonates, infants, toddlers, children, and adolescents: ACTTION recommendations.

Walco GA, Kopecky EA, Weisman SJ, Stinson J, Stevens B, Desjardins PJ, Berde CB, Krane EJ, Anand KJS, Yaster M, Dampier CD, Dworkin RH, Gilron I, Lynn AM, Maxwell LG, Raja S, Schachtel B, Turk DC.

Pain. 2018 Feb;159(2):193-205. doi: 10.1097/j.pain.0000000000001104.

35.

Exploring the interaction between Mycobacterium tuberculosis enolase and human plasminogen using computational methods and experimental techniques.

Rahi A, Dhiman A, Singh D, Lynn AM, Rehan M, Bhatnagar R.

J Cell Biochem. 2018 Feb;119(2):2408-2417. doi: 10.1002/jcb.26403. Epub 2017 Oct 18.

PMID:
28888036
36.

Solvent sensitivity of protein aggregation in Cu, Zn superoxide dismutase: a molecular dynamics simulation study.

Prakash A, Kumar V, Pandey P, Bharti DR, Vishwakarma P, Singh R, Hassan MI, Lynn AM.

J Biomol Struct Dyn. 2018 Aug;36(10):2605-2617. doi: 10.1080/07391102.2017.1364670. Epub 2017 Aug 20.

PMID:
28782426
37.

Patterns of fixation during face recognition: Differences in autism across age.

Fedor J, Lynn A, Foran W, DiCicco-Bloom J, Luna B, O'Hearn K.

Autism. 2018 Oct;22(7):866-880. doi: 10.1177/1362361317714989. Epub 2017 Aug 6.

PMID:
28782371
38.

Elucidation of stable intermediates in urea-induced unfolding pathway of human carbonic anhydrase IX.

Prakash A, Dixit G, Meena NK, Singh R, Vishwakarma P, Mishra S, Lynn AM.

J Biomol Struct Dyn. 2018 Jul;36(9):2391-2406. doi: 10.1080/07391102.2017.1355847. Epub 2017 Jul 28.

PMID:
28705076
39.

QSAR based predictive modeling for anti-malarial molecules.

Bharti DR, Lynn AM.

Bioinformation. 2017 May 31;13(5):154-159. doi: 10.6026/97320630013154. eCollection 2017.

40.

Identification of inhibitors against α-Isopropylmalate Synthase of Mycobacterium tuberculosis using docking-MM/PBSA hybrid approach.

Pandey P, Lynn AM, Bandyopadhyay P.

Bioinformation. 2017 May 31;13(5):144-148. doi: 10.6026/97320630013144. eCollection 2017.

41.

A pre-therapeutic coating for medical devices that prevents the attachment of Candida albicans.

Vargas-Blanco D, Lynn A, Rosch J, Noreldin R, Salerni A, Lambert C, Rao RP.

Ann Clin Microbiol Antimicrob. 2017 May 19;16(1):41. doi: 10.1186/s12941-017-0215-z.

42.

Consensus-Driven Development of a Terminology for Biobanking, the Duke Experience.

Ellis H, Joshi MB, Lynn AJ, Walden A.

Biopreserv Biobank. 2017 Apr;15(2):126-133. doi: 10.1089/bio.2016.0092. Epub 2017 Mar 24.

43.

Structure of a headful DNA-packaging bacterial virus at 2.9 Å resolution by electron cryo-microscopy.

Zhao H, Li K, Lynn AY, Aron KE, Yu G, Jiang W, Tang L.

Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):3601-3606. doi: 10.1073/pnas.1615025114. Epub 2017 Mar 20.

44.

A review of perioperative anesthesia and analgesia for infants: updates and trends to watch.

Martin LD, Jimenez N, Lynn AM.

F1000Res. 2017 Feb 8;6:120. doi: 10.12688/f1000research.10272.1. eCollection 2017. Review.

45.

Distinctive Mechanisms of Adversity and Socioeconomic Inequality in Child Development: A Review and Recommendations for Evidence-Based Policy.

Amso D, Lynn A.

Policy Insights Behav Brain Sci. 2017;4(2):139-146. doi: 10.1177/2372732217721933. Epub 2017 Jul 25.

46.

Model-based glycaemic control: methodology and initial results from neonatal intensive care.

Dickson JL, Chase JG, Lynn A, Shaw GM.

Biomed Tech (Berl). 2017 Apr 1;62(2):225-233. doi: 10.1515/bmt-2016-0051.

PMID:
27811342
47.

Functional connectivity differences in autism during face and car recognition: underconnectivity and atypical age-related changes.

Lynn AC, Padmanabhan A, Simmonds D, Foran W, Hallquist MN, Luna B, O'Hearn K.

Dev Sci. 2018 Jan;21(1). doi: 10.1111/desc.12508. Epub 2016 Oct 16.

48.

Reply.

Lynn AM, Leise MD.

Liver Transpl. 2016 Dec;22(12):1736-1737. doi: 10.1002/lt.24647. No abstract available.

49.

Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease.

Mishra CB, Kumari S, Manral A, Prakash A, Saini V, Lynn AM, Tiwari M.

Eur J Med Chem. 2017 Jan 5;125:736-750. doi: 10.1016/j.ejmech.2016.09.057. Epub 2016 Sep 19.

PMID:
27721157
50.

Insulin kinetics and the Neonatal Intensive Care Insulin-Nutrition-Glucose (NICING) model.

Dickson JL, Pretty CG, Alsweiler J, Lynn A, Chase JG.

Math Biosci. 2017 Feb;284:61-70. doi: 10.1016/j.mbs.2016.08.006. Epub 2016 Aug 30.

PMID:
27590773

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