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Items: 1 to 50 of 209

1.

Energy balance related lifestyle factors and risk of endometrial and colorectal cancer among individuals with lynch syndrome: a systematic review.

Coletta AM, Peterson SK, Gatus LA, Krause KJ, Schembre SM, Gilchrist SC, Pande M, Vilar E, You YN, Rodriguez-Bigas MA, Strong LL, Lynch PM, Lu KH, Basen-Engquist K.

Fam Cancer. 2019 Jun 24. doi: 10.1007/s10689-019-00135-7. [Epub ahead of print] Review.

PMID:
31236808
2.

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas.

Delacruz RGC, Sandoval IT, Chang K, Miller BN, Reyes-Uribe L, Borras E, Lynch PM, Taggart MW, Hawk ET, Vilar E, Jones DA.

Oncotarget. 2019 Jun 11;10(39):3939-3951. doi: 10.18632/oncotarget.27003. eCollection 2019 Jun 11.

3.

Outcomes of disease-specific next-generation sequencing gene panel testing in adolescents and young adults with colorectal cancer.

Mork ME, Rodriguez A, Bannon SA, Lynch PM, Rodriguez-Bigas MA, Thirumurthi S, You YN, Vilar E.

Cancer Genet. 2019 Jun;235-236:77-83. doi: 10.1016/j.cancergen.2019.04.064. Epub 2019 Apr 26.

PMID:
31101557
4.

Health and lifestyle behaviors in colorectal cancer survivors with and without Lynch syndrome.

Donato KM, Moore K, Parker WM, Peterson SK, Gritz ER, Amos CI, Lu KH, Lynch PM, Rodriguez-Bigas MA, You YN, Burton-Chase AM.

J Community Genet. 2019 Apr 23. doi: 10.1007/s12687-019-00421-y. [Epub ahead of print]

PMID:
31016603
5.

Pancreatic Cancer Early Detection and Interception in an Atypical Case of Peutz-Jeghers Syndrome.

Mork M, Quesada PR, Bannon S, Montiel MF, Fleming JB, Lynch PM, Bhutani MS, Lee JH, McAllister F.

Pancreas. 2019 Apr;48(4):e29-e30. doi: 10.1097/MPA.0000000000001293. No abstract available.

PMID:
30973470
6.

Colorectal premalignancy is associated with consensus molecular subtypes 1 and 2.

Chang K, Willis JA, Reumers J, Taggart MW, San Lucas FA, Thirumurthi S, Kanth P, Delker DA, Hagedorn CH, Lynch PM, Ellis LM, Hawk ET, Scheet PA, Kopetz S, Arts J, Guinney J, Dienstmann R, Vilar E.

Ann Oncol. 2018 Oct 1;29(10):2061-2067. doi: 10.1093/annonc/mdy337.

PMID:
30412224
7.

NCCN Guidelines Insights: Colorectal Cancer Screening, Version 1.2018.

Provenzale D, Gupta S, Ahnen DJ, Markowitz AJ, Chung DC, Mayer RJ, Regenbogen SE, Blanco AM, Bray T, Cooper G, Early DS, Ford JM, Giardiello FM, Grady W, Hall MJ, Halverson AL, Hamilton SR, Hampel H, Klapman JB, Larson DW, Lazenby AJ, Llor X, Lynch PM, Mikkelson J, Ness RM, Slavin TP, Sugandha S, Weiss JM, Dwyer MA, Ogba N.

J Natl Compr Canc Netw. 2018 Aug;16(8):939-949. doi: 10.6004/jnccn.2018.0067.

PMID:
30099370
8.

Role of the Personal KinetiGraph in the routine clinical assessment of Parkinson's disease: recommendations from an expert panel.

Pahwa R, Isaacson SH, Torres-Russotto D, Nahab FB, Lynch PM, Kotschet KE.

Expert Rev Neurother. 2018 Aug;18(8):669-680. doi: 10.1080/14737175.2018.1503948. Epub 2018 Jul 26.

PMID:
30032695
9.

Physical activity and the risk of colorectal cancer in Lynch syndrome.

Dashti SG, Win AK, Hardikar SS, Glombicki SE, Mallenahalli S, Thirumurthi S, Peterson SK, You YN, Buchanan DD, Figueiredo JC, Campbell PT, Gallinger S, Newcomb PA, Potter JD, Lindor NM, Le Marchand L, Haile RW, Hopper JL, Jenkins MA, Basen-Engquist KM, Lynch PM, Pande M.

Int J Cancer. 2018 Nov 1;143(9):2250-2260. doi: 10.1002/ijc.31611. Epub 2018 Aug 7.

PMID:
29904935
10.

Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome.

Chang K, Taggart MW, Reyes-Uribe L, Borras E, Riquelme E, Barnett RM, Leoni G, San Lucas FA, Catanese MT, Mori F, Diodoro MG, You YN, Hawk ET, Roszik J, Scheet P, Kopetz S, Nicosia A, Scarselli E, Lynch PM, McAllister F, Vilar E.

JAMA Oncol. 2018 Aug 1;4(8):1085-1092. doi: 10.1001/jamaoncol.2018.1482.

11.

Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies.

Pande M, Joon A, Brewster AM, Chen WV, Hopper JL, Eng C, Shete S, Casey G, Schumacher F, Lin Y, Harrison TA, White E, Ahsan H, Andrulis IL, Whittemore AS, John EM, Ko Win A, Makalic E, Schmidt DF, Kapuscinski MK, Ochs-Balcom HM, Gallinger S, Jenkins MA, Newcomb PA, Lindor NM, Peters U, Amos CI, Lynch PM.

PLoS One. 2018 Apr 26;13(4):e0196245. doi: 10.1371/journal.pone.0196245. eCollection 2018.

12.

NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 3.2017.

Gupta S, Provenzale D, Regenbogen SE, Hampel H, Slavin TP, Hall MJ, Llor X, Chung DC, Ahnen DJ, Bray T, Cooper G, Early DS, Ford JM, Giardiello FM, Grady W, Halverson AL, Hamilton SR, Klapman JB, Larson DW, Lazenby AJ, Lynch PM, Markowitz AJ, Mayer RJ, Ness RM, Samadder NJ, Shike M, Sugandha S, Weiss JM, Dwyer MA, Ogba N.

J Natl Compr Canc Netw. 2017 Dec;15(12):1465-1475. doi: 10.6004/jnccn.2017.0176.

PMID:
29223984
13.

Colorectal Cancer Genetics Screening in the Community: Are We Ready? Can We Do It?

Lynch PM.

Clin Gastroenterol Hepatol. 2018 Jan;16(1):21-23. doi: 10.1016/j.cgh.2017.09.049. Epub 2017 Oct 5. No abstract available.

PMID:
28987506
14.

Children's International Polyposis (CHIP) study: a randomized, double-blind, placebo-controlled study of celecoxib in children with familial adenomatous polyposis.

Burke CA, Phillips R, Berger MF, Li C, Essex MN, Iorga D, Lynch PM.

Clin Exp Gastroenterol. 2017 Jul 19;10:177-185. doi: 10.2147/CEG.S121841. eCollection 2017.

15.

In Silico Systems Biology Analysis of Variants of Uncertain Significance in Lynch Syndrome Supports the Prioritization of Functional Molecular Validation.

Borras E, Chang K, Pande M, Cuddy A, Bosch JL, Bannon SA, Mork ME, Rodriguez-Bigas MA, Taggart MW, Lynch PM, You YN, Vilar E.

Cancer Prev Res (Phila). 2017 Oct;10(10):580-587. doi: 10.1158/1940-6207.CAPR-17-0058. Epub 2017 Aug 1.

16.

Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis.

Gausachs M, Borras E, Chang K, Gonzalez S, Azuara D, Delgado Amador A, Lopez-Doriga A, San Lucas FA, Sanjuan X, Paules MJ, Taggart MW, Davies GE, Ehli EA, Fowler J, Moreno V, Pineda M, You YN, Lynch PM, Lazaro C, Navin NE, Scheet PA, Hawk ET, Capella G, Vilar E.

Clin Cancer Res. 2017 Oct 1;23(19):5936-5947. doi: 10.1158/1078-0432.CCR-17-0821. Epub 2017 Jun 23.

17.

Can Microsatellite Status of Colorectal Cancer Be Reliably Assessed after Neoadjuvant Therapy?

Goldstein JB, Wu W, Borras E, Masand G, Cuddy A, Mork ME, Bannon SA, Lynch PM, Rodriguez-Bigas M, Taggart MW, Wu J, Scheet P, Kopetz S, You YN, Vilar E.

Clin Cancer Res. 2017 Sep 1;23(17):5246-5254. doi: 10.1158/1078-0432.CCR-16-2994. Epub 2017 May 18.

18.

A comparison between Lynch syndrome and sporadic colorectal cancer survivors' satisfaction with their healthcare providers.

Burton-Chase AM, Parker WM, Polivka KM, Gritz ER, Amos CI, Lu KH, Lynch PM, Rodriguez-Bigas MA, Nancy You Y, Peterson SK.

Cancer Med. 2017 Mar;6(3):698-707. doi: 10.1002/cam4.1033. Epub 2017 Feb 17.

19.

Health-related quality of life in colorectal cancer survivors: are there differences between sporadic and hereditary patients?

Burton-Chase AM, Parker WM, Donato KM, McCormick S, Gritz ER, Amos CI, Lu KH, Lynch PM, Rodriguez-Bigas MA, Nancy You Y, Peterson SK.

J Patient Rep Outcomes. 2017;2(1):21. doi: 10.1186/s41687-018-0047-4. Epub 2018 May 1.

20.

Identification of MSH2 inversion of exons 1-7 in clinical evaluation of families with suspected Lynch syndrome.

Mork ME, Rodriguez A, Taggart MW, Rodriguez-Bigas MA, Lynch PM, Bannon SA, You YN, Vilar E.

Fam Cancer. 2017 Jul;16(3):357-361. doi: 10.1007/s10689-016-9960-y.

21.

Cancer screening behaviors and risk perceptions among family members of colorectal cancer patients with unexplained mismatch repair deficiency.

Katz LH, Advani S, Burton-Chase AM, Fellman B, Polivka KM, Yuan Y, Lynch PM, Peterson SK.

Fam Cancer. 2017 Apr;16(2):231-237. doi: 10.1007/s10689-016-9947-8.

22.

Clinical and economic benefits of integrated pump/CGM technology therapy in patients with type 1 diabetes in Colombia.

Gomez AM, Alfonso-Cristancho R, Orozco JJ, Lynch PM, Prieto D, Saunders R, Roze S, Valencia JE.

Endocrinol Nutr. 2016 Nov;63(9):466-474. doi: 10.1016/j.endonu.2016.05.011. Epub 2016 Aug 30. English, Spanish.

PMID:
27595241
23.

Genetic/Familial High-Risk Assessment: Colorectal Version 1.2016, NCCN Clinical Practice Guidelines in Oncology.

Provenzale D, Gupta S, Ahnen DJ, Bray T, Cannon JA, Cooper G, David DS, Early DS, Erwin D, Ford JM, Giardiello FM, Grady W, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Klapman JB, Larson DW, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Regenbogen SE, Samadder NJ, Shike M, Steinbach G, Weinberg D, Dwyer M, Darlow S.

J Natl Compr Canc Netw. 2016 Aug;14(8):1010-30.

PMID:
27496117
24.

DNA Mismatch Repair Deficiency in Rectal Cancer: Benchmarking Its Impact on Prognosis, Neoadjuvant Response Prediction, and Clinical Cancer Genetics.

de Rosa N, Rodriguez-Bigas MA, Chang GJ, Veerapong J, Borras E, Krishnan S, Bednarski B, Messick CA, Skibber JM, Feig BW, Lynch PM, Vilar E, You YN.

J Clin Oncol. 2016 Sep 1;34(25):3039-46. doi: 10.1200/JCO.2016.66.6826. Epub 2016 Jul 18.

25.

Genomic Landscape of Colorectal Mucosa and Adenomas.

Borras E, San Lucas FA, Chang K, Zhou R, Masand G, Fowler J, Mork ME, You YN, Taggart MW, McAllister F, Jones DA, Davies GE, Edelmann W, Ehli EA, Lynch PM, Hawk ET, Capella G, Scheet P, Vilar E.

Cancer Prev Res (Phila). 2016 Jun;9(6):417-27. doi: 10.1158/1940-6207.CAPR-16-0081. Epub 2016 May 24.

26.

Chemoprevention of hereditary colon cancers: time for new strategies.

Ricciardiello L, Ahnen DJ, Lynch PM.

Nat Rev Gastroenterol Hepatol. 2016 Jun;13(6):352-61. doi: 10.1038/nrgastro.2016.56. Epub 2016 Apr 20. Review.

PMID:
27095653
27.

Chemoprevention of familial adenomatous polyposis.

Lynch PM.

Fam Cancer. 2016 Jul;15(3):467-75. doi: 10.1007/s10689-016-9901-9. Review.

PMID:
27083160
28.

Identification of a novel PMS2 alteration c.505C>G (R169G) in trans with a PMS2 pathogenic mutation in a patient with constitutional mismatch repair deficiency.

Mork ME, Borras E, Taggart MW, Cuddy A, Bannon SA, You YN, Lynch PM, Ramirez PT, Rodriguez-Bigas MA, Vilar E.

Fam Cancer. 2016 Oct;15(4):587-91. doi: 10.1007/s10689-016-9902-8.

29.

Outcome of EMR as an alternative to surgery in patients with complex colon polyps.

Raju GS, Lum PJ, Ross WA, Thirumurthi S, Miller E, Lynch PM, Lee JH, Bhutani MS, Shafi MA, Weston BR, Pande M, Bresalier RS, Rashid A, Mishra L, Davila ML, Stroehlein JR.

Gastrointest Endosc. 2016 Aug;84(2):315-25. doi: 10.1016/j.gie.2016.01.067. Epub 2016 Feb 6.

30.

A proposed staging system and stage-specific interventions for familial adenomatous polyposis.

Lynch PM, Morris JS, Wen S, Advani SM, Ross W, Chang GJ, Rodriguez-Bigas M, Raju GS, Ricciardiello L, Iwama T, Rossi BM, Pellise M, Stoffel E, Wise PE, Bertario L, Saunders B, Burt R, Belluzzi A, Ahnen D, Matsubara N, B├╝low S, Jespersen N, Clark SK, Erdman SH, Markowitz AJ, Bernstein I, De Haas N, Syngal S, Moeslein G.

Gastrointest Endosc. 2016 Jul;84(1):115-125.e4. doi: 10.1016/j.gie.2015.12.029. Epub 2016 Jan 6.

31.

Colorectal Cancer Screening, Version 1.2015.

Provenzale D, Jasperson K, Ahnen DJ, Aslanian H, Bray T, Cannon JA, David DS, Early DS, Erwin D, Ford JM, Giardiello FM, Gupta S, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Klapman JB, Larson DW, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Rao MS, Regenbogen SE, Shike M, Steinbach G, Weinberg D, Dwyer MA, Freedman-Cass DA, Darlow S; National comprehensive cancer netwok.

J Natl Compr Canc Netw. 2015 Aug;13(8):959-68; quiz 968.

PMID:
26285241
32.

Screening adherence and cancer risk perceptions in colorectal cancer survivors with Lynch-like syndrome.

Katz LH, Burton-Chase AM, Advani S, Fellman B, Polivka KM, Yuan Y, Lynch PM, Peterson SK.

Clin Genet. 2016 Mar;89(3):392-8. doi: 10.1111/cge.12653. Epub 2015 Sep 14.

33.

Mutation spectrum and risk of colorectal cancer in African American families with Lynch syndrome.

Guindalini RS, Win AK, Gulden C, Lindor NM, Newcomb PA, Haile RW, Raymond V, Stoffel E, Hall M, Llor X, Ukaegbu CI, Solomon I, Weitzel J, Kalady M, Blanco A, Terdiman J, Shuttlesworth GA, Lynch PM, Hampel H, Lynch HT, Jenkins MA, Olopade OI, Kupfer SS.

Gastroenterology. 2015 Nov;149(6):1446-53. doi: 10.1053/j.gastro.2015.07.052. Epub 2015 Aug 3.

34.

High Prevalence of Hereditary Cancer Syndromes in Adolescents and Young Adults With Colorectal Cancer.

Mork ME, You YN, Ying J, Bannon SA, Lynch PM, Rodriguez-Bigas MA, Vilar E.

J Clin Oncol. 2015 Nov 1;33(31):3544-9. doi: 10.1200/JCO.2015.61.4503. Epub 2015 Jul 20.

35.

A Prospective Six Sigma Quality Improvement Trial to Optimize Universal Screening for Genetic Syndrome Among Patients With Young-Onset Colorectal Cancer.

Dineen S, Lynch PM, Rodriguez-Bigas MA, Bannon S, Taggart M, Reeves C, Modaro C, Overman M, Chang GJ, Skibber JM, You YN.

J Natl Compr Canc Netw. 2015 Jul;13(7):865-72.

PMID:
26150580
36.

The Case for Universal Testing of Colorectal Tumors for Microsatellite Instability: A Coming Mismatch Between Clinical and Laboratory Testing.

Lynch PM.

Dig Dis Sci. 2015 Aug;60(8):2225-7. doi: 10.1007/s10620-015-3739-0. No abstract available.

PMID:
26123836
37.

Natural language processing as an alternative to manual reporting of colonoscopy quality metrics.

Raju GS, Lum PJ, Slack RS, Thirumurthi S, Lynch PM, Miller E, Weston BR, Davila ML, Bhutani MS, Shafi MA, Bresalier RS, Dekovich AA, Lee JH, Guha S, Pande M, Blechacz B, Rashid A, Routbort M, Shuttlesworth G, Mishra L, Stroehlein JR, Ross WA.

Gastrointest Endosc. 2015 Sep;82(3):512-9. doi: 10.1016/j.gie.2015.01.049. Epub 2015 Apr 22.

38.

An international randomised trial of celecoxib versus celecoxib plus difluoromethylornithine in patients with familial adenomatous polyposis.

Lynch PM, Burke CA, Phillips R, Morris JS, Slack R, Wang X, Liu J, Patterson S, Sinicrope FA, Rodriguez-Bigas MA, Half E, Bulow S, Latchford A, Clark S, Ross WA, Malone B, Hasson H, Richmond E, Hawk E.

Gut. 2016 Feb;65(2):286-95. doi: 10.1136/gutjnl-2014-307235. Epub 2015 Mar 19.

39.

Detection rates of premalignant polyps during screening colonoscopy: time to revise quality standards?

Ross WA, Thirumurthi S, Lynch PM, Rashid A, Pande M, Shafi MA, Lee JH, Raju GS.

Gastrointest Endosc. 2015 Mar;81(3):567-74. doi: 10.1016/j.gie.2014.07.030. Epub 2015 Jan 10.

40.

Role of microsatellite instability-low as a diagnostic biomarker of Lynch syndrome in colorectal cancer.

Vilar E, Mork ME, Cuddy A, Borras E, Bannon SA, Taggart MW, Ying J, Broaddus RR, Luthra R, Rodriguez-Bigas MA, Lynch PM, You YQ.

Cancer Genet. 2014 Oct-Dec;207(10-12):495-502. doi: 10.1016/j.cancergen.2014.10.002. Epub 2014 Oct 13.

41.

DNA damage caused by inorganic particulate matter on Raji and HepG2 cell lines exposed to ultraviolet radiation.

Xiao M, Helsing AV, Lynch PM, El-Naggar A, Alegre MM, Robison RA, O'Neill KL.

Mutat Res Genet Toxicol Environ Mutagen. 2014 Sep 1;771:6-14. doi: 10.1016/j.mrgentox.2014.06.004. Epub 2014 Jun 23.

PMID:
25308436
42.

Combined colonoscopy and endometrial biopsy cancer screening results in women with Lynch syndrome.

Nebgen DR, Lu KH, Rimes S, Keeler E, Broaddus R, Munsell MF, Lynch PM.

Gynecol Oncol. 2014 Oct;135(1):85-9. doi: 10.1016/j.ygyno.2014.08.017. Epub 2014 Aug 19.

43.

Colorectal cancer screening in the American Indian/Alaska Native population: progress and at least one new challenge.

Lynch PM.

Cancer. 2014 Oct 15;120(20):3105-7. doi: 10.1002/cncr.28848. Epub 2014 Aug 13. No abstract available.

44.

Patient-reported disease knowledge and educational needs in Lynch syndrome: findings of an interactive multidisciplinary patient conference.

Bannon SA, Mork M, Vilar E, Peterson SK, Lu K, Lynch PM, Rodriguez-Bigas MA, You YN.

Hered Cancer Clin Pract. 2014 Feb 5;12(1):1. doi: 10.1186/1897-4287-12-1.

45.

Establishing a diagnostic road map for MUTYH-associated polyposis.

Borras E, Taggart MW, Lynch PM, Vilar E.

Clin Cancer Res. 2014 Mar 1;20(5):1061-3. doi: 10.1158/1078-0432.CCR-13-3295. Epub 2014 Jan 31.

46.

Communication and technology in genetic counseling for familial cancer.

Lynch HT, Snyder C, Stacey M, Olson B, Peterson SK, Buxbaum S, Shaw T, Lynch PM.

Clin Genet. 2014 Mar;85(3):213-22. doi: 10.1111/cge.12317. Epub 2013 Dec 20. Review.

47.

When and how to perform genetic testing for inherited colorectal cancer syndromes.

Lynch PM.

J Natl Compr Canc Netw. 2013 Dec 1;11(12):1577-83. Review.

PMID:
24335689
48.

Colorectal cancer screening.

Burt RW, Cannon JA, David DS, Early DS, Ford JM, Giardiello FM, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Jasperson K, Klapman JB, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Provenzale D, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D, Dwyer M, Freedman-Cass D; National comprehensive cancer network.

J Natl Compr Canc Netw. 2013 Dec 1;11(12):1538-75.

PMID:
24335688
49.

Tumor-based screening for hereditary nonpolyposis colorectal cancer: does age-based selection optimize yield?

Lynch PM.

J Oncol Pract. 2013 Jul;9(4):180-1. doi: 10.1200/JOP.2012.000786. Epub 2013 Apr 2. No abstract available.

50.

Adenoma detection in patients undergoing a comprehensive colonoscopy screening.

Raju GS, Vadyala V, Slack R, Krishna SG, Ross WA, Lynch PM, Bresalier RS, Hawk E, Stroehlein JR.

Cancer Med. 2013 Jun;2(3):391-402. doi: 10.1002/cam4.73. Epub 2013 Apr 20.

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