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Items: 1 to 50 of 61

1.

Loss-Framed Financial Incentives and Personalized Goal-Setting to Increase Physical Activity Among Ischemic Heart Disease Patients Using Wearable Devices: The ACTIVE REWARD Randomized Trial.

Chokshi NP, Adusumalli S, Small DS, Morris A, Feingold J, Ha YP, Lynch MD, Rareshide CAL, Hilbert V, Patel MS.

J Am Heart Assoc. 2018 Jun 13;7(12). pii: e009173. doi: 10.1161/JAHA.118.009173.

2.

Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations.

Philippeos C, Telerman SB, Oulès B, Pisco AO, Shaw TJ, Elgueta R, Lombardi G, Driskell RR, Soldin M, Lynch MD, Watt FM.

J Invest Dermatol. 2018 Apr;138(4):811-825. doi: 10.1016/j.jid.2018.01.016. Epub 2018 Jan 31.

3.

Fibroblast heterogeneity: implications for human disease.

Lynch MD, Watt FM.

J Clin Invest. 2018 Jan 2;128(1):26-35. doi: 10.1172/JCI93555. Epub 2018 Jan 2. Review.

4.

The Completed PacBio Single-Molecule Real-Time Sequence of Methylosinus trichosporium Strain OB3b Reveals the Presence of a Third Large Plasmid.

Heil JR, Lynch MDJ, Cheng J, Matysiakiewicz O, D'Alessio M, Charles TC.

Genome Announc. 2017 Dec 7;5(49). pii: e01349-17. doi: 10.1128/genomeA.01349-17.

5.

Spatial constraints govern competition of mutant clones in human epidermis.

Lynch MD, Lynch CNS, Craythorne E, Liakath-Ali K, Mallipeddi R, Barker JN, Watt FM.

Nat Commun. 2017 Oct 24;8(1):1119. doi: 10.1038/s41467-017-00993-8.

6.

Managing the SOS Response for Enhanced CRISPR-Cas-Based Recombineering in E. coli through Transient Inhibition of Host RecA Activity.

Moreb EA, Hoover B, Yaseen A, Valyasevi N, Roecker Z, Menacho-Melgar R, Lynch MD.

ACS Synth Biol. 2017 Dec 15;6(12):2209-2218. doi: 10.1021/acssynbio.7b00174. Epub 2017 Oct 2.

PMID:
28915012
7.

Age-specific profiling of cutaneous allergy at high temporal resolution suggests age-related alterations in regulatory immune function.

Lynch MD, McFadden JP, White JM, Banerjee P, White IR.

J Allergy Clin Immunol. 2017 Nov;140(5):1451-1453.e5. doi: 10.1016/j.jaci.2017.03.054. Epub 2017 Jun 9. No abstract available.

PMID:
28606588
8.

Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice.

De Palma G, Lynch MD, Lu J, Dang VT, Deng Y, Jury J, Umeh G, Miranda PM, Pigrau Pastor M, Sidani S, Pinto-Sanchez MI, Philip V, McLean PG, Hagelsieb MG, Surette MG, Bergonzelli GE, Verdu EF, Britz-McKibbin P, Neufeld JD, Collins SM, Bercik P.

Sci Transl Med. 2017 Mar 1;9(379). pii: eaaf6397. doi: 10.1126/scitranslmed.aaf6397.

PMID:
28251905
9.

SSUnique: Detecting Sequence Novelty in Microbiome Surveys.

Lynch MD, Neufeld JD.

mSystems. 2016 Dec 20;1(6). pii: e00133-16. doi: 10.1128/mSystems.00133-16. eCollection 2016 Nov-Dec.

10.

A dynamic landscape of allergen associations in delayed-type cutaneous hypersensitivity.

Lynch MD, White JM, McFadden JP, Wang Y, White IR, Banerjee P.

Br J Dermatol. 2017 Jan;176(1):184-196. doi: 10.1111/bjd.14793. Epub 2016 Nov 29.

PMID:
27285898
11.

Into new territory: improved microbial synthesis through engineering of the essential metabolic network.

Lynch MD.

Curr Opin Biotechnol. 2016 Apr;38:106-11. doi: 10.1016/j.copbio.2016.01.009. Epub 2016 Feb 10. Review.

PMID:
26874263
12.

Applications of platelet-rich plasma in dermatology: A critical appraisal of the literature.

Lynch MD, Bashir S.

J Dermatolog Treat. 2016;27(3):285-9. doi: 10.3109/09546634.2015.1094178. Epub 2015 Oct 14. Review.

PMID:
26466811
13.

Ecology and exploration of the rare biosphere.

Lynch MD, Neufeld JD.

Nat Rev Microbiol. 2015 Apr;13(4):217-29. doi: 10.1038/nrmicro3400. Epub 2015 Mar 2. Review.

PMID:
25730701
14.

Disseminated coxsackievirus A6 affecting children with atopic dermatitis.

Lynch MD, Sears A, Cookson H, Lew T, Laftah Z, Orrin L, Zuckerman M, Creamer D, Higgins E.

Clin Exp Dermatol. 2015 Jul;40(5):525-8. doi: 10.1111/ced.12574. Epub 2015 Feb 10.

PMID:
25677678
15.

Bacterial community composition of chronic periodontitis and novel oral sampling sites for detecting disease indicators.

Galimanas V, Hall MW, Singh N, Lynch MD, Goldberg M, Tenenbaum H, Cvitkovitch DG, Neufeld JD, Senadheera DB.

Microbiome. 2014 Aug 26;2:32. doi: 10.1186/2049-2618-2-32. eCollection 2014.

16.

Aquatic metagenomes implicate Thaumarchaeota in global cobalamin production.

Doxey AC, Kurtz DA, Lynch MD, Sauder LA, Neufeld JD.

ISME J. 2015 Feb;9(2):461-71. doi: 10.1038/ismej.2014.142. Epub 2014 Aug 15.

17.

Evaluating bias of illumina-based bacterial 16S rRNA gene profiles.

Kennedy K, Hall MW, Lynch MD, Moreno-Hagelsieb G, Neufeld JD.

Appl Environ Microbiol. 2014 Sep;80(18):5717-22. doi: 10.1128/AEM.01451-14. Epub 2014 Jul 7.

18.

Authors' reply to Cockayne and colleagues.

Lynch MD, Cliffe J, Morris-Jones R.

BMJ. 2014 Jun 24;348:g4092. doi: 10.1136/bmj.g4092. No abstract available.

PMID:
24961397
19.

Norwegian deep-water coral reefs: cultivation and molecular analysis of planktonic microbial communities.

Jensen S, Lynch MD, Ray JL, Neufeld JD, Hovland M.

Environ Microbiol. 2015 Oct;17(10):3597-609. doi: 10.1111/1462-2920.12531. Epub 2014 Jul 7.

PMID:
24911121
20.

Management of cutaneous viral warts.

Lynch MD, Cliffe J, Morris-Jones R.

BMJ. 2014 May 27;348:g3339. doi: 10.1136/bmj.g3339. Review. No abstract available.

PMID:
24865780
21.

A lexicon of assessment and outcome measures for telemental health.

Shore JH, Mishkind MC, Bernard J, Doarn CR, Bell I Jr, Bhatla R, Brooks E, Caudill R, Cohn ER, Delphin BJ, Eppolito A, Fortney J, Friedl K, Hirsch P, Jordan PJ, Kim TJ, Luxton DD, Lynch MD, Maheu MM, McVeigh FL, Nelson EL, Officer C, O'Neil PT, Roberts LJ, Rye C, Turvey C, Vo A.

Telemed J E Health. 2014 Mar;20(3):282-92. doi: 10.1089/tmj.2013.0357. Epub 2014 Jan 29.

PMID:
24476192
22.

Exploring links between pH and bacterial community composition in soils from the Craibstone Experimental Farm.

Bartram AK, Jiang X, Lynch MD, Masella AP, Nicol GW, Dushoff J, Neufeld JD.

FEMS Microbiol Ecol. 2014 Feb;87(2):403-15. doi: 10.1111/1574-6941.12231. Epub 2013 Oct 25.

23.

AXIOME: automated exploration of microbial diversity.

Lynch MDj, Masella AP, Hall MW, Bartram AK, Neufeld JD.

Gigascience. 2013 Mar 13;2(1):3. doi: 10.1186/2047-217X-2-3.

24.

Targeted recovery of novel phylogenetic diversity from next-generation sequence data.

Lynch MD, Bartram AK, Neufeld JD.

ISME J. 2012 Nov;6(11):2067-77. doi: 10.1038/ismej.2012.50. Epub 2012 Jul 12.

25.

The liver toxicity biomarker study phase I: markers for the effects of tolcapone or entacapone.

McBurney RN, Hines WM, VonTungeln LS, Schnackenberg LK, Beger RD, Moland CL, Han T, Fuscoe JC, Chang CW, Chen JJ, Su Z, Fan XH, Tong W, Booth SA, Balasubramanian R, Courchesne PL, Campbell JM, Graber A, Guo Y, Juhasz P, Li TY, Lynch MD, Morel NM, Plasterer TN, Takach EJ, Zeng C, Beland FA.

Toxicol Pathol. 2012 Aug;40(6):951-64. doi: 10.1177/0192623312444026. Epub 2012 May 9.

PMID:
22573522
26.

Bacterial biogeography of the human digestive tract.

Stearns JC, Lynch MD, Senadheera DB, Tenenbaum HC, Goldberg MB, Cvitkovitch DG, Croitoru K, Moreno-Hagelsieb G, Neufeld JD.

Sci Rep. 2011;1:170. doi: 10.1038/srep00170. Epub 2011 Nov 25.

27.

Intragenic enhancers act as alternative promoters.

Kowalczyk MS, Hughes JR, Garrick D, Lynch MD, Sharpe JA, Sloane-Stanley JA, McGowan SJ, De Gobbi M, Hosseini M, Vernimmen D, Brown JM, Gray NE, Collavin L, Gibbons RJ, Flint J, Taylor S, Buckle VJ, Milne TA, Wood WG, Higgs DR.

Mol Cell. 2012 Feb 24;45(4):447-58. doi: 10.1016/j.molcel.2011.12.021. Epub 2012 Jan 19.

28.

Identification of a 21 amino acid peptide conferring 3-hydroxypropionic acid stress-tolerance to Escherichia coli.

Warnecke TE, Lynch MD, Lipscomb ML, Gill RT.

Biotechnol Bioeng. 2012 May;109(5):1347-52. doi: 10.1002/bit.24398. Epub 2012 Jan 2.

PMID:
22161628
29.

An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment.

Lynch MD, Smith AJ, De Gobbi M, Flenley M, Hughes JR, Vernimmen D, Ayyub H, Sharpe JA, Sloane-Stanley JA, Sutherland L, Meek S, Burdon T, Gibbons RJ, Garrick D, Higgs DR.

EMBO J. 2012 Jan 18;31(2):317-29. doi: 10.1038/emboj.2011.399. Epub 2011 Nov 4.

30.

A NEW LOOK AT AN ANCIENT ORDER: GENERIC REVISION OF THE BANGIALES (RHODOPHYTA)(1).

Sutherland JE, Lindstrom SC, Nelson WA, Brodie J, Lynch MD, Hwang MS, Choi HG, Miyata M, Kikuchi N, Oliveira MC, Farr T, Neefus C, Mols-Mortensen A, Milstein D, Müller KM.

J Phycol. 2011 Oct;47(5):1131-51. doi: 10.1111/j.1529-8817.2011.01052.x. Epub 2011 Sep 13.

PMID:
27020195
31.

Polycomb eviction as a new distant enhancer function.

Vernimmen D, Lynch MD, De Gobbi M, Garrick D, Sharpe JA, Sloane-Stanley JA, Smith AJ, Higgs DR.

Genes Dev. 2011 Aug 1;25(15):1583-8. doi: 10.1101/gad.16985411.

32.

Prevalence of anaerobic ammonium-oxidizing bacteria in contaminated groundwater.

Moore TA, Xing Y, Lazenby B, Lynch MD, Schiff S, Robertson WD, Timlin R, Lanza S, Ryan MC, Aravena R, Fortin D, Clark ID, Neufeld JD.

Environ Sci Technol. 2011 Sep 1;45(17):7217-25. doi: 10.1021/es201243t. Epub 2011 Aug 11.

PMID:
21786759
33.

Generation of multimillion-sequence 16S rRNA gene libraries from complex microbial communities by assembling paired-end illumina reads.

Bartram AK, Lynch MD, Stearns JC, Moreno-Hagelsieb G, Neufeld JD.

Appl Environ Microbiol. 2011 Jun;77(11):3846-52. doi: 10.1128/AEM.02772-10. Epub 2011 Apr 1. Erratum in: Appl Environ Microbiol. 2011 Aug;77(15):5569.

34.

Aquaporin expression in the brains of patients with or without cerebral amyloid angiopathy.

Moftakhar P, Lynch MD, Pomakian JL, Vinters HV.

J Neuropathol Exp Neurol. 2010 Dec;69(12):1201-9. doi: 10.1097/NEN.0b013e3181fd252c.

35.

Broad-host-range vectors for protein expression across gram negative hosts.

Prior JE, Lynch MD, Gill RT.

Biotechnol Bioeng. 2010 Jun 1;106(2):326-32. doi: 10.1002/bit.22695.

PMID:
20148414
36.

Rapid dissection of a complex phenotype through genomic-scale mapping of fitness altering genes.

Warnecke TE, Lynch MD, Karimpour-Fard A, Lipscomb ML, Handke P, Mills T, Ramey CJ, Hoang T, Gill RT.

Metab Eng. 2010 May;12(3):241-50. doi: 10.1016/j.ymben.2009.12.002. Epub 2010 Jan 6.

PMID:
20060059
37.

Cerebral microinfarcts associated with severe cerebral beta-amyloid angiopathy.

Soontornniyomkij V, Lynch MD, Mermash S, Pomakian J, Badkoobehi H, Clare R, Vinters HV.

Brain Pathol. 2010 Mar;20(2):459-67. doi: 10.1111/j.1750-3639.2009.00322.x. Epub 2009 Jul 16.

38.

Genes restoring redox balance in fermentation-deficient E. coli NZN111.

Singh A, Lynch MD, Gill RT.

Metab Eng. 2009 Nov;11(6):347-54. doi: 10.1016/j.ymben.2009.07.002. Epub 2009 Jul 21.

PMID:
19628049
39.

The liver toxicity biomarker study: phase I design and preliminary results.

McBurney RN, Hines WM, Von Tungeln LS, Schnackenberg LK, Beger RD, Moland CL, Han T, Fuscoe JC, Chang CW, Chen JJ, Su Z, Fan XH, Tong W, Booth SA, Balasubramanian R, Courchesne PL, Campbell JM, Graber A, Guo Y, Juhasz PJ, Li TY, Lynch MD, Morel NM, Plasterer TN, Takach EJ, Zeng C, Beland FA.

Toxicol Pathol. 2009 Jan;37(1):52-64. doi: 10.1177/0192623308329287. Epub 2009 Jan 26.

PMID:
19171931
40.

Insights into the evolutionary origins of clostridial neurotoxins from analysis of the Clostridium botulinum strain A neurotoxin gene cluster.

Doxey AC, Lynch MD, Müller KM, Meiering EM, McConkey BJ.

BMC Evol Biol. 2008 Nov 14;8:316. doi: 10.1186/1471-2148-8-316.

41.

Parallel mapping of genotypes to phenotypes contributing to overall biological fitness.

Gall S, Lynch MD, Sandoval NR, Gill RT.

Metab Eng. 2008 Nov;10(6):382-93. doi: 10.1016/j.ymben.2008.08.003. Epub 2008 Aug 23.

PMID:
18789396
42.

A genomics approach to improve the analysis and design of strain selections.

Warnecke TE, Lynch MD, Karimpour-Fard A, Sandoval N, Gill RT.

Metab Eng. 2008 May-Jul;10(3-4):154-65. doi: 10.1016/j.ymben.2008.04.004. Epub 2008 May 9.

PMID:
18514004
43.

Functionalized magnetonanoparticles for MRI diagnosis and localization in epilepsy.

Akhtari M, Bragin A, Cohen M, Moats R, Brenker F, Lynch MD, Vinters HV, Engel J Jr.

Epilepsia. 2008 Aug;49(8):1419-30. doi: 10.1111/j.1528-1167.2008.01615.x. Epub 2008 May 8.

44.

Genome-scale analysis of anti-metabolite directed strain engineering.

Bonomo J, Lynch MD, Warnecke T, Price JV, Gill RT.

Metab Eng. 2008 Mar;10(2):109-20. Epub 2007 Nov 5.

PMID:
18093856
45.

Fibroblast growth factor 1 gene and hypertension: from the quantitative trait locus to positional analysis.

Tomaszewski M, Charchar FJ, Lynch MD, Padmanabhan S, Wang WY, Miller WH, Grzeszczak W, Maric C, Zukowska-Szczechowska E, Dominiczak AF.

Circulation. 2007 Oct 23;116(17):1915-24. Epub 2007 Oct 1.

PMID:
17909102
46.

SCALEs: multiscale analysis of library enrichment.

Lynch MD, Warnecke T, Gill RT.

Nat Methods. 2007 Jan;4(1):87-93. Epub 2006 Nov 12.

PMID:
17099705
47.

Diversity of basidiomycetes in michigan agricultural soils.

Lynch MD, Thorn RG.

Appl Environ Microbiol. 2006 Nov;72(11):7050-6. Epub 2006 Sep 1.

48.

Breast cancer, stem cells and prospects for therapy.

Lynch MD, Cariati M, Purushotham AD.

Breast Cancer Res. 2006;8(3):211. Epub 2006 Jul 3. Review.

49.

Malignant eccrine poroma in breast cancer-related lymphoedema.

Lynch MD, Jones AE, Marker A, Grant JW, Purushotham AD.

Ann R Coll Surg Engl. 2004 Nov;86(6):W32-5.

50.

Broad host range vectors for stable genomic library construction.

Lynch MD, Gill RT.

Biotechnol Bioeng. 2006 May 5;94(1):151-8.

PMID:
16496398

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