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Items: 1 to 50 of 212

1.

Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors.

Kharel Y, Agah S, Huang T, Mendelson AJ, Eletu OT, Barkey-Bircann P, Gesualdi J, Smith JS, Santos WL, Lynch KR.

PLoS One. 2018 Apr 19;13(4):e0192179. doi: 10.1371/journal.pone.0192179. eCollection 2018.

2.

Increasing circulating sphingosine-1-phosphate attenuates lung injury during ex vivo lung perfusion.

Mehaffey JH, Charles EJ, Narahari AK, Schubert S, Laubach VE, Teman NR, Lynch KR, Kron IL, Sharma AK.

J Thorac Cardiovasc Surg. 2018 Aug;156(2):910-917. doi: 10.1016/j.jtcvs.2018.02.090. Epub 2018 Mar 11.

PMID:
29609890
3.

Track and Field Practice and Bone Outcomes among Adolescents: A Pilot Study (ABCD-Growth Study).

Faustino-da-Silva YDSV, Agostinete RR, Werneck AO, Maillane-Vanegas S, Lynch KR, Exupério IN, Ito IH, Fernandes RA.

J Bone Metab. 2018 Feb;25(1):35-42. doi: 10.11005/jbm.2018.25.1.35. Epub 2018 Feb 28.

4.

Food Insecurity and Violence in the Home: Investigating Exposure to Violence and Victimization Among Preschool-Aged Children.

Jackson DB, Lynch KR, Helton JJ, Vaughn MG.

Health Educ Behav. 2018 Oct;45(5):756-763. doi: 10.1177/1090198118760683. Epub 2018 Mar 13.

PMID:
29532691
5.

Implementing Domestic Violence Gun Confiscation Policy in Rural and Urban Communities: Assessing the Perceived Risk, Benefits, and Barriers.

Lynch KR, Logan TK.

J Interpers Violence. 2017 Jul 1:886260517719081. doi: 10.1177/0886260517719081. [Epub ahead of print]

PMID:
29294823
6.

Great Sexpectations: The Impact of Participant Gender, Defendant Desirability, and Date Cost on Attributions of a Date Rape Victim and Defendant.

Lynch KR, Jewell JA, Wasarhaley NE, Golding JM, Renzetti CM.

J Interpers Violence. 2017 May 1:886260517709800. doi: 10.1177/0886260517709800. [Epub ahead of print]

PMID:
29294759
7.

Alcohol Use, Hostile Sexism, and Religious Self-Regulation: Investigating Risk and Protective Factors of IPV Perpetration.

Lynch KR, Renzetti CM.

J Interpers Violence. 2017 May 1:886260517708758. doi: 10.1177/0886260517708758. [Epub ahead of print]

PMID:
29294750
8.

Mobilization studies in mice deficient in sphingosine kinase 2 support a crucial role of the plasma level of sphingosine-1-phosphate in the egress of hematopoietic stem progenitor cells.

Adamiak M, Chelvarajan L, Lynch KR, Santos WL, Abdel-Latif A, Ratajczak MZ.

Oncotarget. 2017 Jul 24;8(39):65588-65600. doi: 10.18632/oncotarget.19514. eCollection 2017 Sep 12.

9.

Time trends in physical activity of adult users of the Brazilian National Health System: 2010-2014. Longitudinal study.

Turi BC, Codogno JS, Fernandes RA, Lynch KR, Kokubun E, Monteiro HL.

Sao Paulo Med J. 2017 Jul-Aug;135(4):369-375. doi: 10.1590/1516-3180.2017.0025190317. Epub 2017 Aug 7.

10.

Adverse Housing Conditions and Early-Onset Delinquency.

Jackson DB, Newsome J, Lynch KR.

Am J Community Psychol. 2017 Sep;60(1-2):160-174. doi: 10.1002/ajcp.12153. Epub 2017 Aug 9.

PMID:
28792078
11.

Impact of Martial Arts (Judo, Karate, and Kung Fu) on Bone Mineral Density Gains in Adolescents of Both Genders: 9-Month Follow-Up.

Ito IH, Kemper HCG, Agostinete RR, Lynch KR, Christofaro DGD, Ronque ER, Fernandes RA.

Pediatr Exerc Sci. 2017 Nov 1;29(4):496-503. doi: 10.1123/pes.2017-0019. Epub 2017 Sep 22.

PMID:
28714773
12.

The Impact of Training Load on Bone Mineral Density of Adolescent Swimmers: A Structural Equation Modeling Approach.

Agostinete RR, Maillane-Vanegas S, Lynch KR, Turi-Lynch B, Coelho-E-Silva MJ, Campos EZ, Cayres SU, Araújo Fernandes R.

Pediatr Exerc Sci. 2017 Nov 1;29(4):520-528. doi: 10.1123/pes.2017-0008. Epub 2017 Oct 11.

PMID:
28605234
13.

Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and in Vivo Activity.

Childress ES, Kharel Y, Brown AM, Bevan DR, Lynch KR, Santos WL.

J Med Chem. 2017 May 11;60(9):3933-3957. doi: 10.1021/acs.jmedchem.7b00233. Epub 2017 Apr 25.

14.

TV viewing time is associated with increased all-cause mortality in Brazilian adults independent of physical activity.

Turi BC, Monteiro HL, Lemes ÍR, Codogno JS, Lynch KR, Asahi Mesquita CA, Fernandes RA.

Scand J Med Sci Sports. 2018 Feb;28(2):596-603. doi: 10.1111/sms.12882. Epub 2017 Apr 26.

PMID:
28329411
15.

Lysophosphatidic acid counteracts glucagon-induced hepatocyte glucose production via STAT3.

Taddeo EP, Hargett SR, Lahiri S, Nelson ME, Liao JA, Li C, Slack-Davis JK, Tomsig JL, Lynch KR, Yan Z, Harris TE, Hoehn KL.

Sci Rep. 2017 Mar 9;7(1):127. doi: 10.1038/s41598-017-00210-y.

16.

Impact sports and bone fractures among adolescents.

Lynch KR, Kemper HCG, Turi-Lynch B, Agostinete RR, Ito IH, Luiz-De-Marco R, Rodrigues-Junior MA, Fernandes RA.

J Sports Sci. 2017 Dec;35(24):2421-2426. doi: 10.1080/02640414.2016.1272708. Epub 2016 Dec 27.

PMID:
28026207
17.

Endothelial Sphingosine 1‑Phosphate Receptor‑1 Mediates Protection and Recovery from Acute Kidney Injury.

Perry HM, Huang L, Ye H, Liu C, Sung SJ, Lynch KR, Rosin DL, Bajwa A, Okusa MD.

J Am Soc Nephrol. 2016 Nov;27(11):3383-3393. Epub 2016 Mar 9.

18.

Sphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ.

Bajwa A, Huang L, Kurmaeva E, Ye H, Dondeti KR, Chroscicki P, Foley LS, Balogun ZA, Alexander KJ, Park H, Lynch KR, Rosin DL, Okusa MD.

J Am Soc Nephrol. 2017 Apr;28(4):1145-1161. doi: 10.1681/ASN.2016030306. Epub 2016 Oct 31.

19.

Prolonged Practice of Swimming Is Negatively Related to Bone Mineral Density Gains in Adolescents.

Ribeiro-Dos-Santos MR, Lynch KR, Agostinete RR, Maillane-Vanegas S, Turi-Lynch B, Ito IH, Luiz-de-Marco R, Rodrigues-Junior MA, Fernandes RA.

J Bone Metab. 2016 Aug;23(3):149-55. doi: 10.11005/jbm.2016.23.3.149. Epub 2016 Aug 31.

20.

Sphingosine kinase inhibitors: a review of patent literature (2006-2015).

Lynch KR, Thorpe SB, Santos WL.

Expert Opin Ther Pat. 2016 Dec;26(12):1409-1416. Epub 2016 Aug 30. Review.

21.

Structural Requirements and Docking Analysis of Amidine-Based Sphingosine Kinase 1 Inhibitors Containing Oxadiazoles.

Houck JD, Dawson TK, Kennedy AJ, Kharel Y, Naimon ND, Field SD, Lynch KR, Macdonald TL.

ACS Med Chem Lett. 2016 Mar 1;7(5):487-92. doi: 10.1021/acsmedchemlett.6b00002. eCollection 2016 May 12.

22.

Basketball Affects Bone Mineral Density Accrual in Boys More Than Swimming and Other Impact Sports: 9-mo Follow-Up.

Agostinete RR, Lynch KR, Gobbo LA, Lima MC, Ito IH, Luiz-de-Marco R, Rodrigues-Junior MA, Fernandes RA.

J Clin Densitom. 2016 Jul-Sep;19(3):375-81. doi: 10.1016/j.jocd.2016.04.006. Epub 2016 May 9.

PMID:
27174316
23.

Associations Between Sexual Behavior Norm Beliefs in Relationships and Intimate Partner Rape Judgments.

Lynch KR, Jewell JA, Golding JM, Kembel HB.

Violence Against Women. 2017 Mar;23(4):426-451. doi: 10.1177/1077801216642871. Epub 2016 Jul 9.

PMID:
27153859
24.

Structure-Activity Relationship Studies and Molecular Modeling of Naphthalene-Based Sphingosine Kinase 2 Inhibitors.

Congdon MD, Kharel Y, Brown AM, Lewis SN, Bevan DR, Lynch KR, Santos WL.

ACS Med Chem Lett. 2016 Feb 2;7(3):229-34. doi: 10.1021/acsmedchemlett.5b00304. eCollection 2016 Mar 10.

25.

"You Better Say Your Prayers and Get Ready": Guns Within the Context of Partner Abuse.

Lynch KR, Logan TK.

J Interpers Violence. 2018 Feb;33(4):686-711. doi: 10.1177/0886260515613344. Epub 2015 Nov 5.

PMID:
26545394
26.

Police Officers' Attitudes and Challenges With Charging Stalking.

Lynch KR, Logan TK.

Violence Vict. 2015;30(6):1037-48. doi: 10.1891/0886-6708.VV-D-13-00085. Epub 2015 Oct 5.

PMID:
26440289
27.

Ambivalent Sexism, Alcohol Use, and Intimate Partner Violence Perpetration.

Renzetti CM, Lynch KR, DeWall CN.

J Interpers Violence. 2018 Jan;33(2):183-210. doi: 10.1177/0886260515604412. Epub 2015 Sep 9.

PMID:
26354500
28.

Improving the Credibility of Child Sexual Assault Victims in Court: The Impact of a Sexual Assault Nurse Examiner.

Golding JM, Wasarhaley NE, Lynch KR, Lippert A, Magyarics CL.

Behav Sci Law. 2015 Aug;33(4):493-507. doi: 10.1002/bsl.2188.

PMID:
26294384
29.

Sphingosine Kinase 2 Inhibition and Blood Sphingosine 1-Phosphate Levels.

Kharel Y, Morris EA, Congdon MD, Thorpe SB, Tomsig JL, Santos WL, Lynch KR.

J Pharmacol Exp Ther. 2015 Oct;355(1):23-31. doi: 10.1124/jpet.115.225862. Epub 2015 Aug 4.

30.

The impact of frequency of behavior and type of contact on judgments involving a criminal stalking case.

Magyarics CL, Lynch KR, Golding JM, Lippert A.

Law Hum Behav. 2015 Dec;39(6):602-13. doi: 10.1037/lhb0000151. Epub 2015 Aug 3.

PMID:
26237334
31.

Risk Factors in Arrest of Rural and Urban Female Victims of Intimate Partner Violence.

Lynch KR, Logan TK.

Violence Vict. 2015;30(3):488-501.

PMID:
26118268
32.

The Impact of Gender Stereotypes on Legal Perceptions of Lesbian Intimate Partner Violence.

Wasarhaley NE, Lynch KR, Golding JM, Renzetti CM.

J Interpers Violence. 2017 Mar;32(5):635-658. doi: 10.1177/0886260515586370. Epub 2016 Sep 29.

PMID:
25990382
33.

Impeaching Rape Victims in Criminal Court: Does Concurrent Civil Action Hurt Justice?

Golding JM, Lynch KR, Wasarhaley NE.

J Interpers Violence. 2016 Nov;31(19):3129-3149. doi: 10.1177/0886260515584342. Epub 2016 Jul 11.

PMID:
25944837
34.

Sphingosine-1-phosphate receptor 1 agonism attenuates lung ischemia-reperfusion injury.

Stone ML, Sharma AK, Zhao Y, Charles EJ, Huerter ME, Johnston WF, Kron IL, Lynch KR, Laubach VE.

Am J Physiol Lung Cell Mol Physiol. 2015 Jun 15;308(12):L1245-52. doi: 10.1152/ajplung.00302.2014. Epub 2015 Apr 24.

35.

Structure-activity relationship studies of the lipophilic tail region of sphingosine kinase 2 inhibitors.

Congdon MD, Childress ES, Patwardhan NN, Gumkowski J, Morris EA, Kharel Y, Lynch KR, Santos WL.

Bioorg Med Chem Lett. 2015 Nov 1;25(21):4956-4960. doi: 10.1016/j.bmcl.2015.03.041. Epub 2015 Mar 23.

36.

Decreased peritoneal ovarian cancer growth in mice lacking expression of lipid phosphate phosphohydrolase 1.

Nakayama J, Raines TA, Lynch KR, Slack-Davis JK.

PLoS One. 2015 Mar 13;10(3):e0120071. doi: 10.1371/journal.pone.0120071. eCollection 2015.

37.

Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors.

Patwardhan NN, Morris EA, Kharel Y, Raje MR, Gao M, Tomsig JL, Lynch KR, Santos WL.

J Med Chem. 2015 Feb 26;58(4):1879-1899. doi: 10.1021/jm501760d. Epub 2015 Feb 13.

38.

Drugging sphingosine kinases.

Santos WL, Lynch KR.

ACS Chem Biol. 2015 Jan 16;10(1):225-33. doi: 10.1021/cb5008426. Epub 2014 Nov 19. Review.

39.

Sphingosine 1-phosphate receptor-1 enhances mitochondrial function and reduces cisplatin-induced tubule injury.

Bajwa A, Rosin DL, Chroscicki P, Lee S, Dondeti K, Ye H, Kinsey GR, Stevens BK, Jobin K, Kenwood BM, Hoehn KL, Lynch KR, Okusa MD.

J Am Soc Nephrol. 2015 Apr;26(4):908-25. doi: 10.1681/ASN.2013121351. Epub 2014 Aug 21.

40.

Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD.

Awojoodu AO, Keegan PM, Lane AR, Zhang Y, Lynch KR, Platt MO, Botchwey EA.

Blood. 2014 Sep 18;124(12):1941-50. doi: 10.1182/blood-2014-01-543652. Epub 2014 Jul 29.

41.

Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle.

Taddeo EP, Laker RC, Breen DS, Akhtar YN, Kenwood BM, Liao JA, Zhang M, Fazakerley DJ, Tomsig JL, Harris TE, Keller SR, Chow JD, Lynch KR, Chokki M, Molkentin JD, Turner N, James DE, Yan Z, Hoehn KL.

Mol Metab. 2013 Nov 26;3(2):124-34. doi: 10.1016/j.molmet.2013.11.003. eCollection 2014 Apr.

42.

Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane.

Kenwood BM, Weaver JL, Bajwa A, Poon IK, Byrne FL, Murrow BA, Calderone JA, Huang L, Divakaruni AS, Tomsig JL, Okabe K, Lo RH, Cameron Coleman G, Columbus L, Yan Z, Saucerman JJ, Smith JS, Holmes JW, Lynch KR, Ravichandran KS, Uchiyama S, Santos WL, Rogers GW, Okusa MD, Bayliss DA, Hoehn KL.

Mol Metab. 2013 Nov 28;3(2):114-23. doi: 10.1016/j.molmet.2013.11.005. eCollection 2014 Apr.

43.

Who bought the drinks? Juror perceptions of intoxication in a rape trial.

Lynch KR, Wasarhaley NE, Golding JM, Simcic T.

J Interpers Violence. 2013 Nov;28(16):3205-22. doi: 10.1177/0886260513496900. Epub 2013 Aug 7.

PMID:
23929601
44.

Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis.

Awojoodu AO, Ogle ME, Sefcik LS, Bowers DT, Martin K, Brayman KL, Lynch KR, Peirce-Cottler SM, Botchwey E.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13785-90. doi: 10.1073/pnas.1221309110. Epub 2013 Aug 5.

45.

Measurement of muon capture on the proton to 1% precision and determination of the pseudoscalar coupling gP.

Andreev VA, Banks TI, Carey RM, Case TA, Clayton SM, Crowe KM, Deutsch J, Egger J, Freedman SJ, Ganzha VA, Gorringe T, Gray FE, Hertzog DW, Hildebrandt M, Kammel P, Kiburg B, Knaack S, Kravtsov PA, Krivshich AG, Lauss B, Lynch KR, Maev EM, Maev OE, Mulhauser F, Petitjean C, Petrov GE, Prieels R, Schapkin GN, Semenchuk GG, Soroka MA, Tishchenko V, Vasilyev AA, Vorobyov AA, Vznuzdaev ME, Winter P; MuCap Collaboration.

Phys Rev Lett. 2013 Jan 4;110(1):012504. Epub 2013 Jan 3.

PMID:
23383785
46.

Dendritic cell sphingosine 1-phosphate receptor-3 regulates Th1-Th2 polarity in kidney ischemia-reperfusion injury.

Bajwa A, Huang L, Ye H, Dondeti K, Song S, Rosin DL, Lynch KR, Lobo PI, Li L, Okusa MD.

J Immunol. 2012 Sep 1;189(5):2584-96. doi: 10.4049/jimmunol.1200999. Epub 2012 Aug 1.

47.

Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate.

Kharel Y, Raje M, Gao M, Gellett AM, Tomsig JL, Lynch KR, Santos WL.

Biochem J. 2012 Oct 1;447(1):149-57. doi: 10.1042/BJ20120609.

48.

Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases.

Gellett AM, Kharel Y, Sunkara M, Morris AJ, Lynch KR.

Biochem Biophys Res Commun. 2012 Jun 15;422(4):758-63. doi: 10.1016/j.bbrc.2012.05.077. Epub 2012 May 22.

49.

Building a better sphingosine kinase-1 inhibitor.

Lynch KR.

Biochem J. 2012 May 15;444(1):e1-2. doi: 10.1042/BJ20120567.

PMID:
22533672
50.

Effect of alkyl chain length on sphingosine kinase 2 selectivity.

Knott K, Kharel Y, Raje MR, Lynch KR, Santos WL.

Bioorg Med Chem Lett. 2012 Nov 15;22(22):6817-20. doi: 10.1016/j.bmcl.2012.01.050. Epub 2012 Jan 26.

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