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Items: 1 to 50 of 363

1.

Increased stress associated with head-out plethysmography testing can exacerbate respiratory effects and lead to mortality in rats.

Lynch JJ 3rd, Rossignol E, Moehrle JJ, Van Vleet TR, Marsh KC, Parman T, Mirsalis J, Ottinger SE, Segreti JA, Rao M, Mittelstadt SW.

J Pharmacol Toxicol Methods. 2019 May 11:106580. doi: 10.1016/j.vascn.2019.106580. [Epub ahead of print]

PMID:
31085318
2.

Emergency Department Risk Stratification After Opiate Overdose Is Just the Beginning.

Clemency BM, Lynch JJ, Creighton T, Lindstrom HA.

Acad Emerg Med. 2019 Apr 23. doi: 10.1111/acem.13772. [Epub ahead of print] No abstract available.

PMID:
31012508
3.

Digital and Mechanical Characterization of Ureteral Stent Luminal Reduction in Response to Extrinsic Compression Forces.

Davis NF, Mulvihill JJE, Lynch JJ, Browne E, Bolton DM, Jack GS, Walsh MT.

J Endourol. 2018 Dec;32(12):1148-1153. doi: 10.1089/end.2018.0573. Epub 2018 Oct 23.

PMID:
30221548
4.

Screening Strategies and Methods for Better Off-Target Liability Prediction and Identification of Small-Molecule Pharmaceuticals.

Van Vleet TR, Liguori MJ, Lynch JJ 3rd, Rao M, Warder S.

SLAS Discov. 2019 Jan;24(1):1-24. doi: 10.1177/2472555218799713. Epub 2018 Sep 10.

PMID:
30196745
5.

Analysis of Three Commonly Used Tibia Length Measurement Techniques.

Lynch JJ, Maijanen H, Prescher A.

J Forensic Sci. 2019 Jan;64(1):181-185. doi: 10.1111/1556-4029.13868. Epub 2018 Jul 12.

PMID:
30001468
6.

Z-Transform Method for Pairwise Osteometric Pair-matching.

Warnke-Sommer JD, Lynch JJ, Pawaskar SS, Damann FE.

J Forensic Sci. 2019 Jan;64(1):23-33. doi: 10.1111/1556-4029.13813. Epub 2018 May 14.

PMID:
29758091
7.

Reanalysis of the Trotter Tibia Quandary and its Continued Effect on Stature Estimation of Past-Conflict Service Members.

Lynch JJ, Brown C, Palmiotto A, Maijanen H, Damann F.

J Forensic Sci. 2019 Jan;64(1):171-174. doi: 10.1111/1556-4029.13806. Epub 2018 Apr 23.

PMID:
29684942
8.

An Automated Two-dimensional Pairwise form Registration Method for Pair-matching of Fragmented Skeletal Remains.

Lynch JJ.

J Forensic Sci. 2018 Nov;63(6):1790-1795. doi: 10.1111/1556-4029.13787. Epub 2018 Apr 10.

PMID:
29637565
9.

An Automated Two-Dimensional Form Registration Method for Osteological Pair-Matching.

Lynch JJ.

J Forensic Sci. 2018 Jul;63(4):1236-1242. doi: 10.1111/1556-4029.13670. Epub 2017 Oct 16.

PMID:
29044522
10.

Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis.

Hulverson MA, Choi R, Arnold SLM, Schaefer DA, Hemphill A, McCloskey MC, Betzer DP, Müller J, Vidadala RSR, Whitman GR, Rivas KL, Barrett LK, Hackman RC, Love MS, McNamara CW, Shaughnessy TK, Kondratiuk A, Kurnick M, Banfor PN, Lynch JJ, Freiberg GM, Kempf DJ, Maly DJ, Riggs MW, Ojo KK, Van Voorhis WC.

Int J Parasitol. 2017 Oct;47(12):753-763. doi: 10.1016/j.ijpara.2017.08.006. Epub 2017 Sep 9.

11.

Use of Microcomputed Tomography to Measure the Relaxin-induced Expansion of Intrapubic Ligaments in Mice.

Zimmerman HA, Kennan RP, Zhang C, Shah K, Johns DG, Lynch JJ, Dajee M.

Comp Med. 2017 Aug 1;67(4):330-334.

12.

The Automation of Regression Modeling in Osteometric Sorting: An Ordination Approach.

Lynch JJ.

J Forensic Sci. 2018 May;63(3):798-804. doi: 10.1111/1556-4029.13597. Epub 2017 Jul 21.

PMID:
28731575
13.

An Analysis on the Choice of Alpha Level in the Osteometric Pair-matching of the Os Coxa, Scapula, and Clavicle.

Lynch JJ.

J Forensic Sci. 2018 May;63(3):793-797. doi: 10.1111/1556-4029.13599. Epub 2017 Jul 18.

PMID:
28718882
14.

Solution-Processed Cu2Se Nanocrystal Films with Bulk-Like Thermoelectric Performance.

Forster JD, Lynch JJ, Coates NE, Liu J, Jang H, Zaia E, Gordon MP, Szybowski M, Sahu A, Cahill DG, Urban JJ.

Sci Rep. 2017 Jun 5;7(1):2765. doi: 10.1038/s41598-017-02944-1.

15.

Preclinical abuse liability assessment of ABT-126, an agonist at the α7 nicotinic acetylcholine receptor (nAChR).

Hudzik TJ, Basso AM, Lynch JJ 3rd, Bracken WM, Mohler EG, Kohlhaas KL, Xu H, Haig G, Gault L.

Pharmacol Biochem Behav. 2017 Jul;158:22-31. doi: 10.1016/j.pbb.2017.05.010. Epub 2017 Jun 1.

16.

The Power of Exclusion using Automated Osteometric Sorting: Pair-Matching.

Lynch JJ, Byrd J, LeGarde CB.

J Forensic Sci. 2018 Mar;63(2):371-380. doi: 10.1111/1556-4029.13560. Epub 2017 May 26.

PMID:
28547802
17.

Effects of carvedilol on structural and functional outcomes and plasma biomarkers in the mouse transverse aortic constriction heart failure model.

Hampton C, Rosa R, Szeto D, Forrest G, Campbell B, Kennan R, Wang S, Huang CH, Gichuru L, Ping X, Shen X, Small K, Madwed J, Lynch JJ.

SAGE Open Med. 2017 Mar 30;5:2050312117700057. doi: 10.1177/2050312117700057. eCollection 2017.

18.

Potential functional and pathological side effects related to off-target pharmacological activity.

Lynch JJ 3rd, Van Vleet TR, Mittelstadt SW, Blomme EAG.

J Pharmacol Toxicol Methods. 2017 Sep;87:108-126. doi: 10.1016/j.vascn.2017.02.020. Epub 2017 Feb 16. Review.

PMID:
28216264
19.

Sexual Dimorphism of the First Rib: A Comparative Approach Using Metric and Geometric Morphometric Analyses.

Lynch JJ, Cross P, Heaton V.

J Forensic Sci. 2017 Sep;62(5):1251-1258. doi: 10.1111/1556-4029.13421. Epub 2017 Feb 7.

PMID:
28168691
20.

Discovery of MK-1832, a Kv1.5 inhibitor with improved selectivity and pharmacokinetics.

Wolkenberg SE, Nolt MB, Bilodeau MT, Trotter BW, Manley PJ, Kett NR, Nanda KK, Wu Z, Cato MJ, Kane SA, Kiss L, Spencer RH, Wang J, Lynch JJ, Regan CP, Stump GL, Li B, White R, Yeh S, Dinsmore CJ, Lindsley CW, Hartman GD.

Bioorg Med Chem Lett. 2017 Feb 15;27(4):1062-1069. doi: 10.1016/j.bmcl.2016.12.054. Epub 2017 Jan 16.

PMID:
28131713
21.

Early echocardiographic predictors of outcomes in the mouse transverse aortic constriction heart failure model.

Hampton C, Rosa R, Campbell B, Kennan R, Gichuru L, Ping X, Shen X, Small K, Madwed J, Lynch JJ.

J Pharmacol Toxicol Methods. 2017 Mar - Apr;84:93-101. doi: 10.1016/j.vascn.2016.12.001. Epub 2016 Dec 9.

PMID:
27956205
22.

The FIELDS Instrument Suite for Solar Probe Plus: Measuring the Coronal Plasma and Magnetic Field, Plasma Waves and Turbulence, and Radio Signatures of Solar Transients.

Bale SD, Goetz K, Harvey PR, Turin P, Bonnell JW, de Wit TD, Ergun RE, MacDowall RJ, Pulupa M, Andre M, Bolton M, Bougeret JL, Bowen TA, Burgess D, Cattell CA, Chandran BDG, Chaston CC, Chen CHK, Choi MK, Connerney JE, Cranmer S, Diaz-Aguado M, Donakowski W, Drake JF, Farrell WM, Fergeau P, Fermin J, Fischer J, Fox N, Glaser D, Goldstein M, Gordon D, Hanson E, Harris SE, Hayes LM, Hinze JJ, Hollweg JV, Horbury TS, Howard RA, Hoxie V, Jannet G, Karlsson M, Kasper JC, Kellogg PJ, Kien M, Klimchuk JA, Krasnoselskikh VV, Krucker S, Lynch JJ, Maksimovic M, Malaspina DM, Marker S, Martin P, Martinez-Oliveros J, McCauley J, McComas DJ, McDonald T, Meyer-Vernet N, Moncuquet M, Monson SJ, Mozer FS, Murphy SD, Odom J, Oliverson R, Olson J, Parker EN, Pankow D, Phan T, Quataert E, Quinn T, Ruplin SW, Salem C, Seitz D, Sheppard DA, Siy A, Stevens K, Summers D, Szabo A, Timofeeva M, Vaivads A, Velli M, Yehle A, Werthimer D, Wygant JR.

Space Sci Rev. 2016 Dec;204(1-4):49-82. doi: 10.1007/s11214-016-0244-5. Epub 2016 Mar 31.

23.

Preclinical pharmacology and pharmacokinetics of CERC-301, a GluN2B-selective N-methyl-D-aspartate receptor antagonist.

Garner R, Gopalakrishnan S, McCauley JA, Bednar RA, Gaul SL, Mosser SD, Kiss L, Lynch JJ, Patel S, Fandozzi C, Lagrutta A, Briscoe R, Liverton NJ, Paterson BM, Vornov JJ, Mazhari R.

Pharmacol Res Perspect. 2015 Dec 23;3(6):e00198. doi: 10.1002/prp2.198. eCollection 2015 Dec. Review.

24.

Linking changes in community composition and function under climate change.

Mokany K, Thomson JJ, Lynch JJ, Jordan GJ, Ferrier S.

Ecol Appl. 2015 Dec;25(8):2132-41.

PMID:
26910944
25.

Translational Biomarkers of Neurotoxicity: A Health and Environmental Sciences Institute Perspective on the Way Forward.

Roberts RA, Aschner M, Calligaro D, Guilarte TR, Hanig JP, Herr DW, Hudzik TJ, Jeromin A, Kallman MJ, Liachenko S, Lynch JJ 3rd, Miller DB, Moser VC, O'Callaghan JP, Slikker W Jr, Paule MG.

Toxicol Sci. 2015 Dec;148(2):332-40. doi: 10.1093/toxsci/kfv188. Review.

26.

Diastolic Mitral Regurgitation in a Patient With Complex Native Mitral and Aortic Valve Endocarditis: A Rare Phenomenon With Potential Catastrophic Consequences.

Pulido JN, Lynch JJ, Mauermann WJ, Michelena HI, Rehfeldt KH.

Semin Cardiothorac Vasc Anesth. 2016 Mar;20(1):100-3. doi: 10.1177/1089253215570063. Epub 2015 Feb 2.

PMID:
25648613
27.

Mechanistic insight into the formation of cationic naked nanocrystals generated under equilibrium control.

Doris SE, Lynch JJ, Li C, Wills AW, Urban JJ, Helms BA.

J Am Chem Soc. 2014 Nov 5;136(44):15702-10. doi: 10.1021/ja508675t. Epub 2014 Oct 24.

PMID:
25302526
28.

Neck hematoma complicating endotracheal extubation.

Barbara DW, Smith BC, Lynch JJ.

Can J Anaesth. 2014 Jul;61(7):676-7. doi: 10.1007/s12630-014-0158-1. Epub 2014 Apr 12. No abstract available.

PMID:
24728976
29.

The incidence of vasoplegia in adult patients with right-sided congenital heart defects undergoing cardiac surgery and the correlation with serum vasopressin concentrations.

Wittwer ED, Lynch JJ, Oliver WC Jr, Dearani JA, Burkhart HM, Mauermann WJ.

J Thorac Cardiovasc Surg. 2014 Aug;148(2):625-30. doi: 10.1016/j.jtcvs.2013.10.037. Epub 2013 Nov 23.

30.

Robotic mitral valve repair: a review of anesthetic management of the first 200 patients.

Rodrigues ES, Lynch JJ, Suri RM, Burkhart HM, Li Z, Mauermann WJ, Rehfeldt KH, Nuttall GA.

J Cardiothorac Vasc Anesth. 2014 Feb;28(1):64-68. doi: 10.1053/j.jvca.2013.05.042. Epub 2013 Oct 18.

PMID:
24144629
31.

Comparison of electroencephalography and cerebral oximetry to determine the need for in-line arterial shunting in patients undergoing carotid endarterectomy.

Mauermann WJ, Crepeau AZ, Pulido JN, Lynch JJ, Lobbestael A, Oderich GS, Worrell GA.

J Cardiothorac Vasc Anesth. 2013 Dec;27(6):1253-9. doi: 10.1053/j.jvca.2013.02.013. Epub 2013 Aug 27.

PMID:
23993767
32.

Left Atrial Thrombosis Despite Dabigatran Therapy.

Pandit A, Hakim FA, Srivathsan K, Lynch JJ.

J Atr Fibrillation. 2013 Aug 31;6(2):891. doi: 10.4022/jafib.891. eCollection 2013 Aug-Sep.

33.

Assessment of the abuse liability of ABT-288, a novel histamine H₃ receptor antagonist.

Hudzik TJ, Basso A, Boyce-Rustay JM, Bracken W, Browman KE, Drescher K, Esbenshade TA, Loberg LI, Lynch JJ 3rd, Brioni JD.

Psychopharmacology (Berl). 2013 Jul;228(2):187-97. doi: 10.1007/s00213-013-3027-7. Epub 2013 Feb 28.

PMID:
23455597
34.

Simulation-based postcardiotomy extracorporeal membrane oxygenation crisis training for thoracic surgery residents.

Burkhart HM, Riley JB, Lynch JJ, Suri RM, Greason KL, Joyce LD, Nuttall GA, Stulak J, Schaff HV, Dearani JA.

Ann Thorac Surg. 2013 Mar;95(3):901-6. doi: 10.1016/j.athoracsur.2012.12.015. Epub 2013 Jan 29.

PMID:
23374448
35.

The new antiarrhythmic drug vernakalant: ex vivo study of human atrial tissue from sinus rhythm and chronic atrial fibrillation.

Wettwer E, Christ T, Endig S, Rozmaritsa N, Matschke K, Lynch JJ, Pourrier M, Gibson JK, Fedida D, Knaut M, Ravens U.

Cardiovasc Res. 2013 Apr 1;98(1):145-54. doi: 10.1093/cvr/cvt006. Epub 2013 Jan 22.

PMID:
23341576
36.

Comparison of the intrinsic vasorelaxant and inotropic effects of the antiarrhythmic agents vernakalant and flecainide in human isolated vascular and cardiac tissues.

Lynch JJ Jr, Regan CP, Beatch GN, Gleim GW, Morabito CJ.

J Cardiovasc Pharmacol. 2013 Mar;61(3):226-32. doi: 10.1097/FJC.0b013e31827afd29.

PMID:
23188129
37.

MK-0448, a specific Kv1.5 inhibitor: safety, pharmacokinetics, and pharmacodynamic electrophysiology in experimental animal models and humans.

Pavri BB, Greenberg HE, Kraft WK, Lazarus N, Lynch JJ, Salata JJ, Bilodeau MT, Regan CP, Stump G, Fan L, Mehta A, Wagner JA, Gutstein DE, Bloomfield D.

Circ Arrhythm Electrophysiol. 2012 Dec;5(6):1193-201. doi: 10.1161/CIRCEP.111.969782. Epub 2012 Oct 11.

PMID:
23060423
38.
39.

Rate-dependent effects of vernakalant in the isolated non-remodeled canine left atria are primarily due to block of the sodium channel: comparison with ranolazine and dl-sotalol.

Burashnikov A, Pourrier M, Gibson JK, Lynch JJ, Antzelevitch C.

Circ Arrhythm Electrophysiol. 2012 Apr;5(2):400-8. doi: 10.1161/CIRCEP.111.968305. Epub 2012 Feb 9.

40.

Capsaicin-induced inhibition of platelet aggregation is not mediated by transient receptor potential vanilloid type 1.

Mittelstadt SW, Nelson RA, Daanen JF, King AJ, Kort ME, Kym PR, Lubbers NL, Cox BF, Lynch JJ 3rd.

Blood Coagul Fibrinolysis. 2012 Jan;23(1):94-7. doi: 10.1097/MBC.0b013e32834ddf18.

PMID:
22089942
41.

Coronary artery spasm after Cryo Maze III procedure.

Rajbanshi BG, Rodrigues E, Lynch JJ, Gulati R, Sundt TM 3rd.

Ann Thorac Surg. 2011 Nov;92(5):1884-7. doi: 10.1016/j.athoracsur.2011.04.113. Epub 2011 Oct 31.

PMID:
22051287
42.

Comparison of electrophysiological and antiarrhythmic effects of vernakalant, ranolazine, and sotalol in canine pulmonary vein sleeve preparations.

Sicouri S, Pourrier M, Gibson JK, Lynch JJ, Antzelevitch C.

Heart Rhythm. 2012 Mar;9(3):422-9. doi: 10.1016/j.hrthm.2011.10.021. Epub 2011 Oct 20.

43.

Acute coronary syndrome after mitral valve surgery: a rare complication secondary to mechanical occlusion of the circumflex artery.

Varela NL, Pulido JN, Lynch JJ, Mauermann WJ, Rehfeldt KH.

Int Anesthesiol Clin. 2011 Spring;49(2):32-41. doi: 10.1097/AIA.0b013e3181ff4e10. No abstract available.

PMID:
21441797
44.

Comparison of methods for the assessment of locomotor activity in rodent safety pharmacology studies.

Lynch JJ 3rd, Castagné V, Moser PC, Mittelstadt SW.

J Pharmacol Toxicol Methods. 2011 Jul-Aug;64(1):74-80. doi: 10.1016/j.vascn.2011.03.003. Epub 2011 Mar 23.

PMID:
21406241
45.

Design, synthesis and SAR of a series of 1,3,5-trisubstituted benzenes as thrombin inhibitors.

Isaacs RC, Newton CL, Cutrona KJ, Mercer SP, Payne LS, Stauffer KJ, Williams PD, Cook JJ, Krueger JA, Lewis SD, Lucas BJ, Lyle EA, Lynch JJ, McMasters DR, Naylor-Olsen AM, Michener MT, Wallace AA.

Bioorg Med Chem Lett. 2011 Mar 1;21(5):1536-40. doi: 10.1016/j.bmcl.2010.12.105. Epub 2010 Dec 28.

PMID:
21295467
46.

P3 optimization of functional potency, in vivo efficacy and oral bioavailability in 3-aminopyrazinone thrombin inhibitors bearing non-charged groups at the P1 position.

Isaacs RC, Newton CL, Cutrona KJ, Mercer SP, Dorsey BD, McDonough CM, Cook JJ, Krueger JA, Lewis SD, Lucas BJ, Lyle EA, Lynch JJ, Miller-Stein C, Michener MT, Wallace AA, White RB, Wong BK.

Bioorg Med Chem Lett. 2011 Mar 1;21(5):1532-5. doi: 10.1016/j.bmcl.2010.12.108. Epub 2010 Dec 28.

PMID:
21295466
47.

Effect of calcitonin gene-related peptide receptor antagonism on the systemic blood pressure responses to mechanistically diverse vasomodulators in conscious rats.

Lynch JJ Jr, Detwiler TJ, Kane SA, Regan CP.

J Cardiovasc Pharmacol. 2010 Nov;56(5):518-25. doi: 10.1097/FJC.0b013e3181f5d414.

PMID:
20729756
48.

Passive millimeter wave imaging sensors for commercial markets.

Lynch JJ, Macdonald PA, Moyer HP, Nagele RG.

Appl Opt. 2010 Jul 1;49(19):E7-12. doi: 10.1364/AO.49.0000E7.

PMID:
20648124
49.

Use of paravertebral blockade to facilitate early extubation after minimally invasive cardiac surgery.

Lynch JJ, Mauermann WJ, Pulido JN, Rehfeldt KH, Torres NE.

Semin Cardiothorac Vasc Anesth. 2010 Mar;14(1):47-8. doi: 10.1177/1089253210363009.

PMID:
20472625
50.

Curbside consultation re-imagined: Borrowing from the conflict management toolkit.

Edelstein LM, Lynch JJ, Mokwunye NO, DeRenzo EG.

HEC Forum. 2010 Mar;22(1):41-9. doi: 10.1007/s10730-010-9120-y.

PMID:
20431918

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