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ABCG2 requires a single aromatic amino acid to "clamp" substrates and inhibitors into the binding pocket.

Gose T, Shafi T, Fukuda Y, Das S, Wang Y, Allcock A, Gavan McHarg A, Lynch J, Chen T, Tamai I, Shelat A, Ford RC, Schuetz JD.

FASEB J. 2020 Feb 17. doi: 10.1096/fj.201902338RR. [Epub ahead of print]


Can technology help achieve sustainable intensification? Evidence from milk recording on Irish dairy farms.

Balaine L, Dillon EJ, Läpple D, Lynch J.

Land use policy. 2020 Mar;92. pii: 104437. doi: 10.1016/j.landusepol.2019.104437. Epub 2020 Jan 20.


Long-lived regulatory T cells generated during severe bronchiolitis in infancy influence later progression to asthma.

Lynch JP, Werder RB, Curren BF, Sikder MAA, Ullah A, Sebina I, Rashid RB, Zhang V, Upham JW, Hill GR, Steptoe RJ, Phipps S.

Mucosal Immunol. 2020 Feb 17. doi: 10.1038/s41385-020-0268-8. [Epub ahead of print]


Factors associated with similarity index (SI) scores among a large cohort of undergraduate nursing students.

Lynch J, Ramjan LM, Glew P, Salamonson Y.

Nurse Educ Pract. 2020 Feb 3;43:102735. doi: 10.1016/j.nepr.2020.102735. [Epub ahead of print] No abstract available.


Multiscale computational models can guide experimentation and targeted measurements for crop improvement.

Benes B, Guan K, Lang M, Long SP, Lynch JP, Marshall-Colón A, Peng B, Schnable J, Sweetlove L, Turk M.

Plant J. 2020 Feb 13. doi: 10.1111/tpj.14722. [Epub ahead of print]


Maize genomes to fields (G2F): 2014-2017 field seasons: genotype, phenotype, climatic, soil, and inbred ear image datasets.

McFarland BA, AlKhalifah N, Bohn M, Bubert J, Buckler ES, Ciampitti I, Edwards J, Ertl D, Gage JL, Falcon CM, Flint-Garcia S, Gore MA, Graham C, Hirsch CN, Holland JB, Hood E, Hooker D, Jarquin D, Kaeppler SM, Knoll J, Kruger G, Lauter N, Lee EC, Lima DC, Lorenz A, Lynch JP, McKay J, Miller ND, Moose SP, Murray SC, Nelson R, Poudyal C, Rocheford T, Rodriguez O, Romay MC, Schnable JC, Schnable PS, Scully B, Sekhon R, Silverstein K, Singh M, Smith M, Spalding EP, Springer N, Thelen K, Thomison P, Tuinstra M, Wallace J, Walls R, Wills D, Wisser RJ, Xu W, Yeh CT, de Leon N.

BMC Res Notes. 2020 Feb 12;13(1):71. doi: 10.1186/s13104-020-4922-8.


Self-Reported Burden in Elderly Patients With Localized Prostate Cancer Treated With Stereotactic Body Radiation Therapy (SBRT).

Aghdam N, Pepin A, Carrasquilla M, Johnson C, Danner M, Ayoob M, Yung T, Lei S, Collins BT, Kumar D, Suy S, Lynch J, Collins SP.

Front Oncol. 2020 Jan 22;9:1528. doi: 10.3389/fonc.2019.01528. eCollection 2019.


Setting Priorities to Inform Assessment of Care Homes' Readiness to Participate in Healthcare Innovation: A Systematic Mapping Review and Consensus Process.

Bunn F, Goodman C, Corazzini K, Sharpe R, Handley M, Lynch J, Meyer J, Dening T, Gordon AL.

Int J Environ Res Public Health. 2020 Feb 5;17(3). pii: E987. doi: 10.3390/ijerph17030987.


Examining Bias and Reporting in Oral Health Prediction Modeling Studies.

Du M, Haag D, Song Y, Lynch J, Mittinty M.

J Dent Res. 2020 Feb 6:22034520903725. doi: 10.1177/0022034520903725. [Epub ahead of print]


Shape is only a weak predictor of deep knee flexion kinematics in healthy and osteoarthritic knees.

Lynch JT, Perriman DM, Scarvell JM, Pickering MR, Warmenhoven J, Galvin CR, Neeman T, Besier TF, Smith PN.

J Orthop Res. 2020 Feb 4. doi: 10.1002/jor.24622. [Epub ahead of print]


How many words are Australian children hearing in the first year of life?

Brushe ME, Lynch JW, Reilly S, Melhuish E, Brinkman SA.

BMC Pediatr. 2020 Feb 3;20(1):52. doi: 10.1186/s12887-020-1946-0.


Breast cancer patients' experiences of adherence and persistence to oral endocrine therapy: A qualitative evidence synthesis.

Clancy C, Lynch J, OConnor P, Dowling M.

Eur J Oncol Nurs. 2019 Nov 30;44:101706. doi: 10.1016/j.ejon.2019.101706. [Epub ahead of print]



Reid G, Lynch JP 3rd, Fishbein MC, Clark NM.

Semin Respir Crit Care Med. 2020 Feb;41(1):99-114. doi: 10.1055/s-0039-3401992. Epub 2020 Jan 30.


Evaluation of Suspected Counterfeit Pharmaceutical Tablets Declared to Contain Controlled Substances Using Handheld Raman Spectrometers.

Lanzarotta A, Kimani MM, Thatcher MD, Lynch J, Fulcher M, Witkowski MR, Batson JS.

J Forensic Sci. 2020 Jan 27. doi: 10.1111/1556-4029.14287. [Epub ahead of print]


The history of OCV in India and barriers remaining to programmatic introduction.

Mogasale V, Kanungo S, Pati S, Lynch J, Dutta S.

Vaccine. 2020 Jan 22. pii: S0264-410X(20)30031-1. doi: 10.1016/j.vaccine.2020.01.016. [Epub ahead of print]


A group intervention to improve quality of life for people with advanced dementia living in care homes: the Namaste feasibility cluster RCT.

Froggatt K, Best A, Bunn F, Burnside G, Coast J, Dunleavy L, Goodman C, Hardwick B, Jackson C, Kinley J, Davidson Lund A, Lynch J, Mitchell P, Myring G, Patel S, Algorta GP, Preston N, Scott D, Silvera K, Walshe C.

Health Technol Assess. 2020 Jan;24(6):1-140. doi: 10.3310/hta24060.


Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent.

Zhanel GG, Esquivel J, Zelenitsky S, Lawrence CK, Adam HJ, Golden A, Hink R, Berry L, Schweizer F, Zhanel MA, Bay D, Lagacé-Wiens PRS, Walkty AJ, Lynch JP 3rd, Karlowsky JA.

Drugs. 2020 Jan 22. doi: 10.1007/s40265-020-01257-4. [Epub ahead of print] Review.


Varus alignment of the proximal tibia is associated with structural progression in early to moderate varus osteoarthritis of the knee.

Palmer JS, Jones LD, Monk AP, Nevitt M, Lynch J, Beard DJ, Javaid MK, Price AJ.

Knee Surg Sports Traumatol Arthrosc. 2020 Jan 21. doi: 10.1007/s00167-019-05840-5. [Epub ahead of print]


Clustering Blood Pressure Trajectories in Septic Shock in the Emergency Department.

Prasad V, Lynch JC, Filbin MR, Reisner AT, Heldt T.

Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:494-497. doi: 10.1109/EMBC.2019.8857191.


Children and adolescents with type 1 and type 2 diabetes mellitus in the Pediatric Diabetes Consortium Registries: comparing clinical characteristics and glycaemic control.

Van Name MA, Cheng P, Gal RL, Kollman C, Lynch J, Nelson B, Tamborlane WV; Pediatric Diabetes Consortium.

Diabet Med. 2020 Jan 14. doi: 10.1111/dme.14233. [Epub ahead of print]


Current and future cholera vaccines.

Shaikh H, Lynch J, Kim J, Excler JL.

Vaccine. 2019 Dec 24. pii: S0264-410X(19)31653-6. doi: 10.1016/j.vaccine.2019.12.011. [Epub ahead of print]


Augmented immune responses to a booster dose of oral cholera vaccine in Bangladeshi children less than 5 years of age: Revaccination after an interval of over three years of primary vaccination with a single dose of vaccine.

Chowdhury F, Bhuiyan TR, Akter A, Bhuiyan MS, Khan AI, Tauheed I, Ahmed T, Ferdous J, Dash P, Basher SR, Hakim A, Lynch J, Kim JH, Excler JL, Kim DR, Clemens JD, Qadri F.

Vaccine. 2020 Feb 11;38(7):1753-1761. doi: 10.1016/j.vaccine.2019.12.034. Epub 2019 Dec 24.


The Relationship of Three-Dimensional Joint Space Width on Weight Bearing CT With Pain and Physical Function.

Kothari MD, Rabe KG, Anderson DD, Nevitt MC, Lynch JA, Segal NA, Franz H; Multicenter Osteoarthritis Study Group.

J Orthop Res. 2019 Dec 16. doi: 10.1002/jor.24566. [Epub ahead of print]


The Balance Between Open and Robotic Training among Graduating Urology Residents-Does Surgical Technique Need Monitoring?

Merrill SB, Sohl BS, Thompson RH, Reese AC, Parekh DJ, Lynch JH, Grob BM, Williams DH, Lee RK, Zaslau S, Guzzo TJ, Shenot PJ, Lehman EB, Raman JD.

J Urol. 2019 Dec 11:101097JU0000000000000689. doi: 10.1097/JU.0000000000000689. [Epub ahead of print]


Understanding Misdemeanor Enforcement: The Roles of Calls for Service and Community Characteristics.

Glazener EM, Kozlowski MM, Lynch JP, Smith JS.

J Community Psychol. 2020 Jan;48(1):13-35. doi: 10.1002/jcop.22285. Epub 2019 Dec 9.


Investigating gene expression profiles of whole blood and peripheral blood mononuclear cells using multiple collection and processing methods.

Gautam A, Donohue D, Hoke A, Miller SA, Srinivasan S, Sowe B, Detwiler L, Lynch J, Levangie M, Hammamieh R, Jett M.

PLoS One. 2019 Dec 6;14(12):e0225137. doi: 10.1371/journal.pone.0225137. eCollection 2019.


Risk Factors for BI/NAP1/027 Clostridioides difficile Infections and Clinical Outcomes Compared With Non-NAP1 Strains.

Mani NS, Lynch JB, Fang FC, Chan JD.

Open Forum Infect Dis. 2019 Oct 12;6(12):ofz433. doi: 10.1093/ofid/ofz433. eCollection 2019 Dec.


Measuring early childhood development in multiple contexts: the internal factor structure and reliability of the early Human Capability Index in seven low and middle income countries.

Sincovich A, Gregory T, Zanon C, Santos DD, Lynch J, Brinkman SA.

BMC Pediatr. 2019 Dec 3;19(1):471. doi: 10.1186/s12887-019-1852-5.


Capillary Proliferation in Systemic-Sclerosis-Related Pulmonary Fibrosis: Association with Pulmonary Hypertension.

Seki A, Anklesaria Z, Saggar R, Dodson MW, Schwab K, Liu MC, Charan Ashana D, Miller WD, Vangala S, DerHovanessian A, Channick R, Shaikh F, Belperio JA, Weigt SS, Lynch JP, Ross DJ, Sullivan L, Khanna D, Shapiro SS, Sager J, Gargani L, Stanziola A, Bossone E, Schraufnagel DE, Fishbein G, Xu H, Fishbein MC, Wallace WD, Saggar R.

ACR Open Rheumatol. 2019 Mar 15;1(1):26-36. doi: 10.1002/acr2.1003. eCollection 2019 Mar.


Role of maternal age at birth in child development among Indigenous and non-Indigenous Australian children in their first school year: a population-based cohort study.

Hanly M, Falster K, Banks E, Lynch J, Chambers GM, Brownell M, Dillon A, Eades S, Jorm L.

Lancet Child Adolesc Health. 2020 Jan;4(1):46-57. doi: 10.1016/S2352-4642(19)30334-7. Epub 2019 Nov 19.


Why men with a low-risk prostate cancer select and stay on active surveillance: A qualitative study.

Seaman AT, Taylor KL, Davis K, Nepple KG, Lynch JH, Oberle AD, Hall IJ, Volk RJ, Reisinger HS, Hoffman RM.

PLoS One. 2019 Nov 20;14(11):e0225134. doi: 10.1371/journal.pone.0225134. eCollection 2019.


Genetic components of root architecture and anatomy adjustments to water-deficit stress in spring barley.

Oyiga BC, Palczak J, Wojciechowski T, Lynch JP, Naz AA, Léon J, Ballvora A.

Plant Cell Environ. 2019 Nov 16. doi: 10.1111/pce.13683. [Epub ahead of print]


The morphology of proximal tibiofibular joint (PTFJ) predicts incident radiographic osteoarthritis: data from Osteoarthritis Initiative.

Chang J, Zhu Z, Han W, Zhao Y, Kwoh CK, Lynch JA, Hunter DJ, Ding C.

Osteoarthritis Cartilage. 2020 Feb;28(2):208-214. doi: 10.1016/j.joca.2019.11.001. Epub 2019 Nov 13.


Endotype-phenotyping may predict a treatment response in progressive fibrosing interstitial lung disease.

Hoffmann-Vold AM, Weigt SS, Saggar R, Palchevskiy V, Volkmann ER, Liang LL, Ross D, Ardehali A, Lynch JP 3rd, Belperio JA.

EBioMedicine. 2019 Dec;50:379-386. doi: 10.1016/j.ebiom.2019.10.050. Epub 2019 Nov 12.


Refinement of the rodent pentylenetetrazole proconvulsion assay, which is a good predictor of convulsions in repeat-dose toxicology studies.

Breidenbach L, Hempel K, Mittelstadt SW, Lynch JJ 3rd.

J Pharmacol Toxicol Methods. 2020 Jan - Feb;101:106653. doi: 10.1016/j.vascn.2019.106653. Epub 2019 Nov 12.


Outcome Study of the Pipeline Embolization Device with Shield Technology in Unruptured Aneurysms (PEDSU).

Atasoy D, Kandasamy N, Hart J, Lynch J, Yang SH, Walsh D, Tolias C, Booth TC.

AJNR Am J Neuroradiol. 2019 Dec;40(12):2094-2101. doi: 10.3174/ajnr.A6314. Epub 2019 Nov 14.


Rediscovery of the rare Andean blindsnake Anomalepis colombia Marx 1953 (Serpentes: Anomalepididae) in the wild.

Vanegas-Guerrero J, Martins A, Quiñones-Betancurt E, Lynch JD.

Zootaxa. 2019 Jun 26;4623(3):zootaxa.4623.3.13. doi: 10.11646/zootaxa.4623.3.13.


Prey-size plastics are invading larval fish nurseries.

Gove JM, Whitney JL, McManus MA, Lecky J, Carvalho FC, Lynch JM, Li J, Neubauer P, Smith KA, Phipps JE, Kobayashi DR, Balagso KB, Contreras EA, Manuel ME, Merrifield MA, Polovina JJ, Asner GP, Maynard JA, Williams GJ.

Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24143-24149. doi: 10.1073/pnas.1907496116. Epub 2019 Nov 11.


A longitudinal study of polychlorinated biphenyls and neuropsychological function among older adults from New York State.

Tanner EM, Bloom MS, Kannan K, Lynch J, Wang W, Yucel R, Fitzgerald EF.

Int J Hyg Environ Health. 2020 Jan;223(1):1-9. doi: 10.1016/j.ijheh.2019.10.012. Epub 2019 Nov 6.


Prevalence of self-reported mental disorders in pregnancy and associations with adverse neonatal outcomes: a population-based cross-sectional study.

Mongan D, Lynch J, Hanna D, Shannon C, Hamilton S, Potter C, Gorman C, McCambridge O, Morrow R, Mulholland C.

BMC Pregnancy Childbirth. 2019 Nov 8;19(1):412. doi: 10.1186/s12884-019-2572-4.


Effect of Stellate Ganglion Block Treatment on Posttraumatic Stress Disorder Symptoms: A Randomized Clinical Trial.

Rae Olmsted KL, Bartoszek M, Mulvaney S, McLean B, Turabi A, Young R, Kim E, Vandermaas-Peeler R, Morgan JK, Constantinescu O, Kane S, Nguyen C, Hirsch S, Munoz B, Wallace D, Croxford J, Lynch JH, White R, Walters BB.

JAMA Psychiatry. 2019 Nov 6:1-9. doi: 10.1001/jamapsychiatry.2019.3474. [Epub ahead of print]


Effect of Surgical Versus Medical Therapy on Diabetic Kidney Disease Over 5 Years in Severely Obese Adolescents With Type 2 Diabetes.

Bjornstad P, Hughan K, Kelsey MM, Shah AS, Lynch J, Nehus E, Mitsnefes M, Jenkins T, Xu P, Xie C, Inge T, Nadeau K.

Diabetes Care. 2020 Jan;43(1):187-195. doi: 10.2337/dc19-0708. Epub 2019 Nov 4.


Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease.

Klarin D, Busenkell E, Judy R, Lynch J, Levin M, Haessler J, Aragam K, Chaffin M, Haas M, Lindström S, Assimes TL, Huang J, Min Lee K, Shao Q, Huffman JE, Kabrhel C, Huang Y, Sun YV, Vujkovic M, Saleheen D, Miller DR, Reaven P, DuVall S, Boden WE, Pyarajan S, Reiner AP, Trégouët DA, Henke P, Kooperberg C, Gaziano JM, Concato J, Rader DJ, Cho K, Chang KM, Wilson PWF, Smith NL, O'Donnell CJ, Tsao PS, Kathiresan S, Obi A, Damrauer SM, Natarajan P; INVENT Consortium; Veterans Affairs’ Million Veteran Program.

Nat Genet. 2019 Nov;51(11):1574-1579. doi: 10.1038/s41588-019-0519-3. Epub 2019 Nov 1.


Potentially preventable hospitalisations in children: a comparison of definitions.

Procter AM, Pilkington RM, Lynch JW, Smithers LG, Chittleborough CR.

Arch Dis Child. 2019 Oct 30. pii: archdischild-2019-316945. doi: 10.1136/archdischild-2019-316945. [Epub ahead of print]


Improved calculation of warming-equivalent emissions for short-lived climate pollutants.

Cain M, Lynch J, Allen MR, Fuglestvedt JS, Frame DJ, Macey AH.

NPJ Clim Atmos Sci. 2019 Sep 4;2:29. doi: 10.1038/s41612-019-0086-4.


Reversible cerebral vasoconstrictive syndrome preceded by minor head trauma.

Houlihan LM, Halloran PJO, Lynch J, Widdess-Walsh P, Brennan P, Javadpour M.

Br J Neurosurg. 2019 Oct 25:1-3. doi: 10.1080/02688697.2019.1672858. [Epub ahead of print]


Complications associated with perioperative use of tyrosine kinase inhibitor in cytoreductive nephrectomy.

Carvalho FLF, Zheng C, Witmer K, O'neill J, Lynch JH, Kowalczyk KJ.

Sci Rep. 2019 Oct 24;9(1):15272. doi: 10.1038/s41598-019-51548-4.


How information about perpetrators' nature and nurture influences assessments of their character, mental states, and deserved punishment.

Lynch JM, Lane JD, Berryessa CM, Rottman J.

PLoS One. 2019 Oct 22;14(10):e0224093. doi: 10.1371/journal.pone.0224093. eCollection 2019.


A four-stage process for intervention description and guide development of a practice-based intervention: refining the Namaste Care intervention implementation specification for people with advanced dementia prior to a feasibility cluster randomised trial.

Walshe C, Kinley J, Patel S, Goodman C, Bunn F, Lynch J, Scott D, Lund AD, Stacpoole M, Preston N, Froggatt K.

BMC Geriatr. 2019 Oct 21;19(1):275. doi: 10.1186/s12877-019-1275-z.

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